TB-500: Injury Repair and Muscle Growth

TB-500: Injury Repair and Muscle Growth (Updated 2022)

TB-500 (Thymosin Beta-4) is a potent recovery agent with a tremendous ability to enhance up injury repair and recovery, however, its many benefits also include growth of muscle mass and improved performance. TB-500 is naturally produced in the body, in higher concentration at the site of tissue damage and supports the production of new blood and muscle cells.

It also has incredibly powerful anti-inflammatory effects which can oftentimes offer instant pain relief. Its powerful healing effects have been identified specifically in the tendons, ligaments, muscle, skin, heart and eyes.

Before you read any further you should know that this peptide is banned in almost all competitive sports and events. Also, while it is readily available, Thymosin Beta-4 (also known as TB-500) is sold for research purposes only, not for human consumption.

Benefits of TB-500

  • Increases muscle growth
  • Increases endurance and stamina levels
  • Decreases inflammation in joints
  • Promotes hair growth
  • Rapid healing of wounds
  • Repair of tendons and ligaments
  • Improved flexibility of joints
  • Promotes the regeneration of blood vessels
  • Repairs damaged heart tissue following a heart attack
  • Heals ulcers and lesions (including stomach and intestinal ulcers)
  • Protects and restores neurons after brain injury

What is TB-500?

TB-500 is a synthesised peptide, essentially a short-chain version of the naturally occurring Thymosin Beta-4. It has not been used to treat humans in any tangible method but although it is not considered a veterinary-specific drug, it is often used in the treatment of horses and occasionally dogs.

As there’s little research on human trials we can only go on what we’ve heard and data compiled from various veterinary trials. Its properties are similar to those of HGH and results also appear similar.

Users report increased strength, muscle growth, enhanced recovery and relief from chronic and severe pain as well as improved endurance. There are also reports of increased hair growth, better condition hair and even a lessening of grey hair.

How does TB-500 Work?

In simple terms, TB-500 boosts your body’s protein efficiency. This means that the functions of those proteins are dramatically improved. It increases red blood cell production and improves metabolism and essentially supercharges your body’s ability to grow new cells.

Additionally, thanks to its molecular composition TB-500 is remarkably light and can, therefore, race your system finding areas to improve. It is this that makes it particularly good when it comes to targeting inflammation and pain.

How to Use TB-500

TB-500 is taken as any other peptides; you’ll need to reconstitute it before injecting the solution either subcutaneously or intramuscularly. To take SubQ, find an area of fatty tissue, the abdomen is good but avoid the navel vicinity.

Next, simply clean your hands, wipe the area with a sterile swab, pinch the area with your fingers and then inject your prepared syringe. To take intramuscularly, locate an area of muscular tissue, usually one where you are experiencing pain, and jab the syringe deep into the muscle tissue. It can be a difficult and painful process, but the rewards should outweigh the trouble.

TB-500 Dosage

The dosage depends on the purpose you are using it for, and/or the type of injury or damage that you need to treat. A general guideline would be between 4-8mg of TB-500 per week for the initial loading phase of 4 to 6 weeks, followed by 2-6mg every 2 weeks to maintain its effects. The effects wear off within 2-3 weeks of injection.

Loading phase:

      • Duration: 4-6 weeks
      • Dosage: 4-8mg of TB-500 per week
      • Frequency: 2mg per injection, between 2-4 times per week (depending on the total dosage you choose)

Maintenance phase:

    • Duration: as long as you need
    • Dosage: 2-6mg of TB-500 every 2 weeks
    • Frequency: 2mg per injection, between 2-3 times every 2 weeks (depending on the total 2-week dosage you choose)

Side Effects

The most common side-effect that has been reported by bodybuilders who use this peptide is that of lethargy and possible headaches. Some report experiencing a head rush immediately after injecting it, although this shouldn’t last longer than a minute.

We lack a lot of data on TB-500 but we do know that the medical community is divided over whether or not it has been linked to cancer; some say it increased the rate at which cancer cells grow, while others suggest it may actually promote white blood cells with which to fight it.

Combine TB-500 and BPC-157 for Healing Injury and Repair

BPC-157 and TB-500, which both stimulate wound healing via various biological mechanisms, have synergistic effects when used together. Clinically developed to boost maximum recovery as well as healing together with adjustability, joint flexibility, and also protection against injury.

BPC stands for Body Protective Compound, and that is exactly its function. It was originally discovered to be a protective peptide within our gut and to have a healing effect in both our upper and lower GI tract.

It should be understood that BPC 157 is only a small part of the whole BPC protein, but it is essential for its functionality because it is where binding spots for enzymes are located. The structure of this stable gastric pentadecapeptide consists of 15 amino acids, and looks a little something like this: Gly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val.[1]

Benefits of BPC-157

Some of the world’s top researchers around the worldare working to determine whether BPC 157 contains life-changing properties.

The list of benefits is growing by the day:

  • Useful adjunct to healing almost anything related to the GI tract
  • Heals mitochondrial damage
  • Accelerated healing of ligaments, bones, and tendons
  • Reduces inflammation in autoimmune conditions like rheumatoid arthritis,
  • Protects endothelium and the formation of scar tissue
  • Improves brain health & mood
  • Blocks long term effects of corticosteroid injections
  • Stabilized production of certain hormones and neurotransmitters (eg. serotonin)
  • Protection of the cardiovascular system
  • Reduced drug-induced damage
  • Better general body repair and wound healing
  • Improved body’s response to allergens and viruses

Researcher Ben Greenfield has written extensively about both of them, featuring them in his new book Boundless.

“I’ve personally used peptides BPC-157 and TB-500 to enhance healing and recovery.

“…BPC-157 also accelerates wound healing and, via interaction with the nitric oxide system, protects endothelial tissue and builds blood vessels”

“…TB-500 can be injected in or near any damaged muscle site and sore or injured joint with surprising healing effects”

The similarities between TB-500 and BPC-157

The main similarities between TB-500 and BPC-157 are as follows:

  • Both research peptides have demonstrated anti-inflammatory properties
  • Both research peptides promote angiogenesis (i.e. the formation of new blood vessels)
  • Some researchers contend that TB-500 and BPC-157 increase blood circulation by different mechanisms, but the end result is the same

The differences between TB-500 and BPC-157

There are some obvious differences between these two research peptides.

  • TB-500 has a systemic effect, which means it works regardless of where the injection is made
  • BPC-157 has a localized effect and must be injected near the site of the injury
  • TB-500 works to distribute actin, whereas BPC-157 is directly responsible for increasing actin production.

Keep in mind that the only way to definitively prove the difference between TB-500 and BPC-157 would be to conduct a large-scale clinical trial in which the same type of injury is being treated.

While this type of research has yet to be conducted, it is clear that BPC-157 and TB-500 do not counteract one another.

If anything, anecdotal evidence shows that they work synergistically to speed up the healing process and further accelerate the rate of recovery.

Recommended Dosage for TB-500 and BPC-157

When it comes to TB-500 vs. BPC-157, researchers should know that these research peptides have no safe or recommended dosage.

However, past studies indicate that researchers have dosed them accordingly in the past:

  • BPC-157: 250 mcg injected intramuscularly, daily – once in the morning on an empty stomach and once again right before bed
  • TB-500: 2-4 mg injected intramuscularly, twice a week in evenly spaced doses (ex. Monday and Thursday)

Cycle length is very individual and can vary depending on the specific requirements of the research subject.

Injury Repair & Recovery Stack (MK-677, BPC-157, TB-500)

The Injury Repair & Recovery Stack combines three of the best healing compounds on the market; MK-677, BPC-157 and TB-500. These compounds stimulate wound healing via various biological mechanisms and have synergistic effects when used together. Clinically developed to boost maximum recovery as well as healing together with adjustability, joint flexibility, and also protection against injury.

Pumping Iron Injury Repair & Recovery Stack
Pumping Iron Injury Repair & Recovery Stack
bodybuilder steroids supplements prohormones pct guide

PCT: A Guide to Post Cycle Therapy (Updated 2022)

Post-Cycle Therapy, or PCT for short, is essentially the process of levelling your body’s hormone levels after a SARMs, steroid or prohormone cycle. Simply put, your body may cease to produce or at least lower your natural hormone production when subjected to significantly raised levels of exogenous substances.

To run the most effective PCT, there are 5 goals we want to achieve:

  1. To restart HPTA
  2. Prevent catabolism as our cortisol level rises
  3. Prevent fat gain while retaining enough calories to maintain the muscle
  4. Minimise the loss of strength
  5. To balance our hormones in order to reduce potential negative effects

HPTA Restart Protocol

Restarting the HPTA has been covered many times, a quick evolutionary search on SERMs and you will find many articles relating to the use of both Clomid and Nolvadex, these can be combined together or used solo. To restart HPTA Clomid is a solid choice but you can also use Nolvadex. Both are effective in aiding recovery.

Ostarine Prevents Catabolism During PCT

At this transition point, your body will quickly begin to produce testosterone. It’s here you must be careful not to allow excess cortisol from chewing up your hard-earned muscle. At the same time, your body will have little to no nitrogen which will cause your muscles to crave nutrients that you don’t have.

To counter these effects, prevent catabolism and lessen the amount of muscle loss, a sensible solution is to introduce a non-suppressive anabolic; and this is the greatest opportunity for SARMs to really shine. A low dose at 10mg of Ostarine (MK-2866) will help preserve your muscle gain and increase your nitrogen and IGF levels. This will also help you continue smashing your workouts and even improve muscle pumps.

Cardarine Prevents Fat Gain During PCT

After you’ve dealt with your cortisol levels, you’ll find that the excess testosterone binds with it, rendering it inactive. To prevent fat gain yet keeping your calories up requires a PPAR modulator such as Cardarine (GW-50156). This will regulate the rate at which you burn fat. It does this in a number of ways but essentially it promotes glycogen retention in muscle tissue. This allows the body to alter its metabolism and increase the amount of fat burned instead of using carbs or protein as fuel.

This is a true win/win and means your body retains muscles and yet fat retention is reduced. This, in turn, will give you more stamina and can have the added bonus of reducing cravings.

Balancing Your Hormones During PCT

The drawback to most PCT is the potentially negative side effects. To counter these you need to ensure you keep your hormones balanced. As testosterone levels rise, estrogen levels are also significantly increased and sometimes at a faster rate. Estrogen flooding causes skin problems and can even cause gynecomastia (swelling of the nipples).

To counteract this, Aromasin can be used to inhibit aromatase whilst only increasing your IGF levels by approximately 30%. Aromasin will also prevent estrogen rebound and therefore save you from developing man-boobs. Taken on alternate days, a 12.5mgs dose of Aromasin is great for PCT. It helps up your testosterone levels by actually lowering estrogen.

Benefits of an Aromatase Inhibitor

Although some supplements and SARMs do not convert to estrogen, you will still get the odd one or two guys who experience estrogen-related side effects during their cycle. In such cases, a mild over-the-counter PCT supplement with an aromatase inhibitor is ideal. Mild suppression of testosterone will throw your estrogen levels out of balance and therefore can cause side effects in those who are more prone.

The extent of these side effects will always depend on several factors:

  • Which compound you are using
  • The dose
  • The length of your cycle
  • Your individual predisposition to suppression

For most prohormones and SARMs, your best solution is Arimistane or 6-OXO.

What is 6-OXO?

6-Oxo in Pumping Iron Pro PCT is used to block the conversion of testosterone to estradiol. When the body has more testosterone, the anabolic potential is significantly increased. This will help to build more lean muscle and increase overall body strength.

By having more testosterone, not only will you have increased muscle mass but there is a greater capacity to decrease body fat. Favourable testosterone to estrogen ratio is critical for achieving optimal body composition.

Pumping Iron Pro PCT (6-OXO)
Pumping Iron Pro PCT (6-OXO)

 

  • 6-OXO is the strongest legal aromatase inhibitor on the market
  • Increases lean muscle mass
  • Reduces conversion of testosterone to estradiol
  • Supports muscle retention
  • Increases testosterone:estrogen ratio

What is Arimistane?

Arimistane is a powerful Aromatase Inhibitor (AI) and cortisol blocker that effectively reduces circulating levels of estrogen in the body. It acts as a suicide inhibitor to decrease the number of androgens in the body that can change to estrogen.

Arimistane is a great compound to use for PCT after a prohormone cycle as it increases testosterone whilst lowering estrogen levels. This also means it’s an effective natural muscle builder so you can expect a noticeable increase in muscle growth, strength, muscle hardness and definition.

Enhanced Athlete Arim-RX
Enhanced Athlete Arim-RX

 

  • Blocks high levels of estrogen and cortisol
  • Increases testosterone levels
  • Increases muscle mass
  • Reduces fat storage
  • Improves recovery
  • Improves vascularity
  • Drying and muscle hardening effect
  • Boosts libido

What is Blue Ox?

Enhanced Labs Blue Ox is a natural test booster supplement for men that supports a balanced mood and optimal strength. Blue Ox is often stacked alongside more potent PCT compounds.

Whether you’re off-cycle or just pure natty, our Blue Ox booster is chock-full of essential ingredients that excel in boosting virility and libido.

  • 120 Capsules
  • PCT Regeneration
  • Boost strength and muscle
  • Maintain muscle mass between cycles
  • Increase libido and sexual performance
  • Support healthy energy levels
  • Mood support

 

Enhanced Athlete Blue Ox Test Booster
Enhanced Athlete Blue Ox Test Booster

 

  • Clinically formulated to naturally elevate testosterone levels
  • Contains 9 naturally derived pharmaceutical grade ingredients to increase the body’s own natural testosterone production through multiple different pathways
  • Contains natural anti-estrogen ingredients to regulate estrogen production and remove the metabolites that can cause health concerns like water retention and gynecomastia
  • All of the ingredients in Blue OX have been scientifically verified in human studies

How to do a SARMs PCT

PCT protocol is a highly debated and subjective matter depending on the individual so we can’t advise you on what you should/shouldn’t do but we can give you some guidance. In general, a person cannot be sure which option is best for them unless they do blood tests before and post cycle. Every individual is different and the many factors that will affect your requirements include:

  • Your starting point/baseline
  • Any previous supplement/cycle history
  • Your predisposition/genetics
  • Your age
  • Which compound(s) you are using
  • The dosage(s)
  • The length of your cycle
  • How your body reacts to the compound(s)
  • Side effects encountered – if any

There are some options you can look at:

  1. Aromatase Inhibitor: Suitable for Ostarine and (for some people) potentially other SARMs (such as LGD-4033, LGD-3303, S-4), and/or shorter cycles up to 8 weeks): A mild over-the-counter PCT stack that includes an aromatase inhibitor (Arimistane) such as Arim-RX combined with a high-quality natural testosterone booster such as Blue Ox.
  2. SERMs: For potent compounds (such as RAD-140, YK-11, S-23), advanced stacks and long cycles: A full PCT which includes a SERM (selective estrogen receptor modulator, not to be confused with SARMs), such as Nolvadex and Clomid.
  3. 6-OXO – A very potent aromatase inhibitor that is effective for most people and most compounds including prohormones and SARMs, often combined with a natural testosterone booster such as Blue Ox.

A SERMs PCT protocol for an advanced cycle may look like:

  • Nolvadex (Weeks 1-4): 40mg/40mg/20mg/20mg
  • or Clomid (Weeks 1-4): 50mg/50mg/25mg/25mg

Preparation is key. One thing we can recommend is always having both options on hand in case you find that you need to run a full PCT, even if you haven’t anticipated this possibility.

A proper PCT is equally as important as your cycle. Don’t wait until near the end of your cycle to find the products that you need.

You can also make a judgement on the signs of testosterone suppression if you experience any of these (low energy, low libido, sadness, loss of strength and motivation, chronically poor performance in the gym) after finishing the cycle which will give you an idea of how suppressed you are. This also applies after you complete your PCT to assess the indicators of a successful PCT. Always ensure to take enough time off between cycles to ensure adequate recovery; listen to your body and if in doubt, take more time off.

Read more about Bridging Prohormone Cycles with SARMs to get the most out of your PCT protocol.

Laxogenin: A Natural Anabolic for Lean Muscle Gains

Laxogenin: 100% Natural Anabolic for Lean Muscle Gains

Laxogenin is a plant-derived (100% natural) supplement that offers a safe and non-liver-toxic method of gaining muscle mass as well as many all-round benefits to your health and wellbeing. Some of the notable benefits include building lean muscle, promoting fat loss, lowering cortisol levels and enhancing physical performance and recovery.

5 Alpha Hydroxy Laxogenin commonly referred to as “laxo” for short, has been shown to enhance protein synthesis by over 200%! It is structurally similar to ecdysterone, first discovered in Russia. Research has shown that Laxogenin exhibits similar anabolic properties to anabolic steroids such as Anavar; one of the most popular oral anabolic steroids of all time. However, unlike Anavar, Laxogenin exerts its effects without impacting your own body’s hormone levels meaning there is no suppression of testosterone or associated side effects seen with steroid use.

  • Build lean muscle mass
  • Promote fat loss
  • Enhance physical performance
  • Optimise recovery
  • Lowers the stress hormone cortisol (which causes fat storage and muscle breakdown)

 

Is Laxogenin Suppressive?

Laxogenin belongs to a category of plant hormones called brassinosteroids which have a similar structure to animal steroid hormones. However, plant steroids function through a completely different pathway than human steroid hormones and therefore doesn’t affect the endocrine system. It does not convert to the male sex hormones testosterone and dihydrotestosterone, nor does it convert to estrogen so you won’t need to worry about any adverse effects such as gynecomastia.

This is the highlight – this compound is completely safe for both men and women alike. The ideal supplement of choice for anyone seeking to avoid negative side effects.

Natural Muscle Building with Laxogenin

Laxogenin was first discovered in plants, from the same family that includes mustard leaves – in that form, it’s almost one of your five a day! It has some of the same properties as Anavar (or Oxandrolone), one of the most popular oral anabolic steroids of all time.

At the moment Laxogenin isn’t mainstream. That’s because most of the research that’s been done has been in the old school USSR. Word gets out though, maybe through weightlifters from back in the day – and those guys knew what they were doing.

Plant brassinosteroids and their synthetic derivatives may offer a novel therapeutic strategy for promoting growth, repair, and maintenance of skeletal muscles.

Benefits of Laxogenin

  • Accelerated recovery
  • Reduction in post-workout muscle soreness
  • Powerful anti-inflammatory effects; helps with joint pains
  • Massive pumps and vascularity
  • Faster gains in strength
  • Improved resistance to physical and mental fatigue
  • Safe for both men and women
  • 100% Natural
  • Doesn’t affect your hormones like testosterone and estrogen
  • Safe for women
  • It acts quickly and combines well with protein supplements
  • Fast-acting – ideal for anyone looking to build muscle and strength quickly
  • Can be stacked with pretty much any other compound
  • Can be used for PCT (post cycle therapy) particularly after a prohormone cycle

Supports Fat Loss

The key to what Laxogenin does isn’t totally clear, but what seems to happen is it knocks back production of cortisol, which is a stress hormone – if your cortisol levels are up you can’t grow or produce muscle. With the brakes on the cortisol, your muscles have more chance to bulk up to support your strength. One great side effect is it makes it hard to gain fat, too.

Get the Most of Your Cycle

Laxogenin can be used in many different ways to optimise results whether you’re on-cycle, off-cycle or running a PCT. Its main advantages are:

  • Stacks well with SARMs and prohormones as it doesn’t affect testosterone and estrogen
  • It’s a great alternative to prohormones if you prefer zero suppression
  • An excellent choice to add to your PCT (post cycle therapy)

Thanks to Laxogenin not messing about with your hormones, you can use it long term without hassle. We’ve seen a growing number of people use it for up to 4 months with great results building muscle, reducing body fat, boosting performance and easing mental fatigue.

Mutagenic Labz Metamorphosiz combines Laxogenin (25mg) with Epicatechin 150mg – take 2 capsules per day for best results. Take it with food for better absorption.

How To Run A SARMs PCT (Updated 2020)

The Best SARMs PCT for You (Updated 2021)

One of the most commonly asked questions we get – do you need PCT for SARMs and what are the best SARMs PCT products to use?

First and foremost, SARMs PCT protocol is a highly debated and subjective matter depending on the individual so we can’t advise you on what you should/shouldn’t do but we can give you some guidance. In general, a person cannot be sure which option is best for them unless they get bloodwork done pre and post cycle. Every individual is different and the many factors that will affect your requirements include:

  • Your starting point/baseline
  • Any previous supplement/cycle history
  • Your predisposition/genetics
  • Your age
  • Which compound(s) you are using
  • The dosage(s)
  • The length of your cycle
  • How your body reacts to the compound(s)

The Three Different SARMs PCT Protocols

In general, there are two options to look at when considering your SARMs PCT protocol. These guidelines are NOT instructions – it is down to you as the individual to make a judgement call (or get bloodwork done) in order to choose the best and most effective course of action:

  1. A mild over-the-counter PCT stack that includes an aromatase inhibitor (Arimistane) such as Arim-RX, combined with a high-quality natural testosterone booster such as Black Ox. This is almost always the best option after an Ostarine cycle. For some people, this is also a suitable option for other mid-range SARMs such as LGD-4033, LGD-3303, S-4), and/or shorter cycles up to 8 weeks.
  2. A potent over-the-counter PCT such as Pumping Iron Pro PCT (6-OXO) which is powerful enough for SARMs and pro hormones alike.
  3. A full PCT which includes a SERM, such as Nolvadex and/or Clomid. Ensure to do thorough research on PCT protocols before you consider researching SARMs. This option is often recommended for potent compounds (such as RAD-140, YK-11, S-23), advanced stacks and longer cycles of 12 weeks.

There is also added benefit of adding Cardarine and a low dose of Ostarine to your chosen SARMs PCT protocol, which we go into detail further below.

What is Pro PCT (6-Oxo)?

Pumping Iron Pro PCT is an advanced SARMs and prohormone PCT that contains 6-OXO, a potent aromatase inhibitor which should only be used by experienced users of SARMs and prohormones. This supplement is intended for male athletes only and shouldn’t be used by women. PRO PCT can be used to prevent estrogen related side effects on-cycle as well as a powerful recovery agent for post cycle therapy (PCT)

  • Strongest aromatase inhibitor on the market
  • Increases lean muscle mass
  • Reduces conversion of testosterone to estradiol
  • Supports muscle retention
  • Increases testosterone:estrogen ratio
  • Suitable for vegans (HMPC Veg Cap)

What are SERMs?

SERMs (Selective Estrogen Receptor Modulators) – not to be confused with SARMs – help to control the effects of estrogen and ultimately helps you to avoid gyno (gynecomastia), maintain the muscle mass you’ve gained during your cycle and to boost your testosterone levels. The pharmaceutical grade SERMs are most effective but in some cases, you can use an over-the-counter supplement if your cycle consists of a very mild compound that isn’t too suppressive. The more potent the compound (or the stronger your cycle) the better your SERM needs to be.

The two most common and effective SERMs are:

  1. Clomid (Clomiphene Citrate) is a pharmaceutical drug that has the ability to inhibit estrogen formation. Clomid is often used for heavy cycles or those stacking several compounds. This is because Clomid is the strongest PCT compound but which also carries the greatest side effects. Most users prefer to stick to Nolvadex for their SARMs PCT unless they have no other choice.
  2. Nolvadex (Tamoxifen Citrate) is a pharmaceutical drug used after most steroid cycles to help the user recover. It is a mild yet effective compound which is it’s often preferred over Clomid.

Some users will use a low dosage of Clomid and Nolvadex in their PCT protocol rather than pick one, or the other. This prevents the potential emotional side effects users can experience by using a high dosage of a single SERM. To further enhance recovery, it is recommended to include a good natural testosterone booster, a liver/organ detox supplement, an aromatase inhibitor, Ostarine and Cardarine.

A quick search on SERMs and you will find many articles relating to the use of both Clomid and Nolvadex, these can be combined together or used solo.

Preparation is key. One thing we can recommend is always having both options on hand in case you find that you need to run a full PCT, even if you haven’t anticipated this possibility.

Signs of Testosterone Suppression

You can also make a judgement on the signs of testosterone suppression if you experience any of these:

  • Low energy
  • Low libido
  • Feelings of sadness
  • Loss of strength and motivation
  • Chronically poor performance in the gym

Assess how you feel after finishing the cycle and this should give you an idea of the degree of testosterone suppression. This also applies after you complete your SARMs PCT to assess the indicators of a successful post cycle therapy. Always ensure to take enough time off between cycles to ensure adequate recovery; listen to your body and if in doubt, take more time off.

Should You Use an Aromatase Inhibitor During your SARMs Cycle?

Although some supplements and SARMs do not convert to estrogen, you will still get the odd one or two guys who experience estrogen-related side effects during their cycle. In such cases, a mild over-the-counter SARMs PCT supplement with an aromatase inhibitor is ideal. Mild suppression of testosterone will throw your estrogen levels out of balance and therefore can cause side effects in those who are more prone.

For most prohormones and SARMs PCT, your best solution is Regen-T or Arim-RX.

Ostarine Prevents Catabolism During PCT

At this transition point, your body will quickly begin to produce testosterone. It’s here you must be careful not to allow excess cortisol from chewing up your hard-earned muscle. At the same time, your body will have little to no nitrogen which will cause your muscles to crave nutrients that you don’t have.

To counter these effects, prevent catabolism and lessen the amount of muscle loss, a sensible solution is to introduce a non-suppressive anabolic; and this is the greatest opportunity for this SARM to really shine. A low dose at 10mg of Ostarine (MK-2866) will help preserve your muscle gain and increase your nitrogen and IGF levels. This will also help you continue smashing your workouts and even improve muscle pumps.

Cardarine Prevents Fat Gain During PCT

After you’ve dealt with your cortisol levels, you’ll find that the excess testosterone binds with it, rendering it inactive. To prevent fat gain yet keeping your calories up requires a PPAR modulator such as Cardarine (GW-50156). This will regulate the rate at which you burn fat. It does this in a number of ways but essentially it promotes glycogen retention in muscle tissue. This allows the body to alter its metabolism and increase the amount of fat burned instead of using carbs or protein as fuel.

This is a true win/win and means your body retains muscles and yet fat retention is reduced. This, in turn, will give you more stamina and can have the added bonus of reducing cravings.

Find the latest SARMs PCT supplements here.

The Best Epicatechin Dosage for Bodybuilding (2019)

The Best Epicatechin Dosage for Bodybuilding (2019)

Wondering about the best Epicatechin dosage for bodybuilding? In the bodybuilding world, we talk about a lot of chemicals. From SARMs to prohormones, peptides and everything in between. Yet somewhere down the line after all the benefits we nearly always hear the term side effects. Well, not today guys… because epicatechin (also known as epicat) really is one of the good guys. What is it and is it really any good?

What is Epicatechin?

Epicat is a flavonol. This means a naturally occurring phytochemical and organic compound found in plants. Essentially it’s what puts the super in superfood and it won’t surprise you to hear that it’s found in a good number of these from Green to Tea to Dark Chocolate.

What Does Epicat Do?

Don’t let its humble origins fool you, epicat is one serious bioactive. Over the years numerous studies have proved time and time again that Epicatechin can enhance muscle growth and strength as well as improving vascularity, blood flow and stamina.

Other benefits include its ability to boost the production of nitric oxide and increasing the sensitivity of insulin. All of which adds up to promoting muscle growth and burning fat. One study has found that daily supplementation with Epicatechin also increases endurance levels.

One of its most notable features, Epicatechin has powerful antioxidant properties which mean Epicat is a natural collateral leveller and has also been linked to improved brain function and healthier hearts.

How does Epicat Work?

Studies suggest that epicat is a natural myostatin inhibitor. Myostatin is a protein which effectively governs the limits of muscle growth. The magic comes from follistatin which is known to affect the levels of myostatin in the body and research indicates that it increases the body’s follistatin level.
In short, epicat reduces the effectiveness of myostatin and less effective myostatin means more muscle.

Epicatechin Dosage for Bodybuilding

It’s safe to take a decent amount of epicat and studies suggests that the most effective ratio of 2mg per kg. The highest density of naturally concurring epicatechin comes from pure cocoa at 3mg per gram. Obviously, it’s going to be hard to get that sort of levels just by eating chocolate, although it might be nice to try, so supplements are clearly the way to go. From previous trials, users who were taking daily epicatechin dosage between 150-200mg have reported optimum results in terms of general fitness, muscle building and endurance, which suggests that this would be the best epicatechin dosage to aim for.

Does Epicat Really Have No Side Effects?

Despite numerous studies and countless research projects, science has yet to directly link a single negative effect on the use of epicatechin. In fact, if anything the opposite is true. A 2007 Harvard University study demonstrated that it lowered the risk of mortality from Diabetes, Strokes, Cancer and Heart disease by 10%.

Epicat is Safe for Women

One of the best things about epicat is the fact that it’s beneficial for both men and women alike. Unlike so many other muscle-building supplements, it’s not hormone-based and can produce great effects regardless of chromosomes.

In conclusion

Epicatechin is the real deal. However, it is worth noting that results from Epicat won’t quite be on the same level as you’d expect from SARMs but it will certainly give you the edge you’re looking for. An organic bioactive substance that has no known side effects, promotes muscle, improves stamina and blood flow and has even been proven to protect against death itself… what’s not to love? Oh, and did we mention you can get it in chocolate?

Mutagenic Labz Metamorphosiz

The Mutagenic Labz Metamorphosiz is a blend of Epicat and Laxogenin. The product is natural and can be used by both men and women. Metamorphosiz is also a great product to use while on PCT to help keep hard-earned muscle gains as the ingredients have zero interaction with HPTA. See our Guide To PCT for some helpful tips.

  • 100% Natural
  • Epicatechin (EGCG 98%) 150mg
  • Laxogenin 25mg
  • Indole 3 carbinol 75mg
  • Piperine 5mg
  • Massive pumps and vascularity
  • Can be used by both men and women
  • Best-selling natural muscle builder
  • Shown to increase in protein synthesis and muscle recovery
  • Boost strength and muscle mass
  • Comparable to the effects of prohormones but without impacting your hormones
  • Powerful anti-inflammatory effects; helps with joint pains
  • Increases endurance
Bridging with SARMs

Bridging with SARMs (3 Best Compounds)

One of the biggest challenges you’ll face after a steroid or prohormone cycle is keeping the gains and that’s where bridging with SARMs is a game-changer. It’s the fear of losing gains that encourages the poor habit of staying ‘on-cycle’ for extended periods of time. Clearly, this is not ideal since it can seriously damage your health and organs; our bodies aren’t designed to take that kind of strain. So how can you deal with ‘off-cycle’ blues?

The answer is bridging with SARMs. Simply put, SARMs are built for this.

What is Bridging?

If you are not familiar with bridging, this is the phase of recovery or ‘time-off’ between steroid or prohormone cycles. As some of you will know, it is the time you’re desperately fighting to maintain the same strength, power and endurance as you had during your cycle. This is the time you try to maintain the gains that you’ve worked so hard for.

As a general guideline, the minimum time-off should be the total time on-cycle plus the length of the PCT. For example a 12-week cycle with 4 weeks PCT is a 16-week cycle in total. This would reflect the duration of 16 weeks off, after the PCT.

Inevitably, this is a time when you will lose some strength and you will experience a dip in energy, which can cause physical and mental strain.

Don’t despair. This is a time when SARMs truly shine.

This is where “bridging” comes into play. For athletes on SARMs, a perfect bridge is one that allows one to maintain a huge majority of gains whilst helping to restore hormonal balance.

Benefits of Bridging with SARMs

SARMs still don’t get the credit they deserve in the bodybuilding community but good quality SARMs, at the right dose, can provide the perfect bridge when taking time off. Although there is some confusion, SARMs are not anabolics and some can benefit your recovery phase, providing the dosage is low.

SARMs like Ostarine and Andarine were designed specifically to prevent muscle loss and lend themselves perfectly to that function. Not only that, but used at a low dose they can give the impression of still being ‘on-cycle’ and can help firm up your neural drive. Physiologically, they increase anabolic activity and thus will not only prevent muscle loss but also aid recovery.

Top 3 SARMS for Bridging

#1 Ostarine (MK-2866)

Ostarine prevents catabolism during your bridging phase, and also improves insulin resistance and lowers blood glucose levels.

At this transitioning point, your body will begin to produce testosterone but you must be careful not to allow excess cortisol from chewing up your hard-earned muscle. At the same time, your body will have little to no nitrogen which will cause your muscles to crave nutrients that you don’t have.

To counter these effects, prevent catabolism and lessen the amount of muscle loss, a low dose Ostarine helps to preserve your muscle mass and increase your nitrogen and IGF levels. This will also help you continue smashing your workouts and even improve muscle pumps.

#2 Cardarine (GW-501516)

Although not a SARM, it’s often found in the same category. Cardarine prevents fat gain. After you’ve dealt with your cortisol levels, you’ll find that the excess testosterone binds with it, rendering it inactive.

To prevent fat gain yet keeping your calories up requires a PPAR modulator such as Cardarine (GW-50156). This will regulate the rate at which you burn fat. It does this in a number of ways but essentially it promotes glycogen retention in muscle tissue. This allows the body to alter its metabolism and increase the amount of fat burned instead of using carbs or protein as fuel.

This is a true win/win and means your body retains muscles and yet fat retention is reduced. This, in turn, will give you more stamina and can have the added bonus of reducing cravings.

#3 Andarine (S-4)

Andarine is one of the most researched SARMs, often used for bridging because it is very minimally suppressive. Andarine has shown the most favourable ratio of anabolic/androgenic effects. This means more gains and fewer unwanted side-effects. This is also why it makes a fantastic SARM for women.

This dry compound yields superb results famed for the hard, chiselled look. It not only increased muscle mass and calcium production for increased bone density but it did so in a highly selective manner. When applied to humans, this means it is able to selectively stimulate anabolic activity, allowing the user to mostly surpass any of the nasty side effects associated with products of similar potency.

The 12 Week SARMs Bridge

This is an example of the ideal SARMs bridge, which would follow your prohormone or steroid cycle. Bridging with SARMs would begin immediately after completing your cycle and PCT (i.e. the bridge is going to fill the ‘off-cycle’ period that would usually follow your cycle).

Weeks 1-12 – Andarine (S-4) 50mg per day (25mg in the AM and 25mg in the PM)
Weeks 1-12 – Cardarine (GW-510516) 20mg per day (full dose 30 minutes before workout)
Weeks 1-12 – Ostarine (MK-2866) 10mg per day  (full dose once per day in the AM)
Weeks 9-12 – Arimistane/DAA

Weeks 13-16 – Mini PCT:
Clomid 50/25/25/25
Cardarine (GW-501516) 20mg per day

How to Bridge Between Cycles Effectively

There are 3 key factors to consider when bridging with SARMs, and each is equally important. It’s not just about the supplements you use; its the foundation you lay and that comes from the following:

Mindset:

You can’t just let yourself go when you move ‘off-cycle’. Your chemistry may be changing, but you can’t allow your focus to slip. Keeping up a solid mental state is essential if you don’t want to lose your gains. Losing your aggression and neural drive can be as damaging as losing muscle gain so it’s important to keep your mind sharp.

Diet:

You don’t need us to tell you how important diet is to bodybuilding. Indeed some would say it’s the most important aspect of all. It’s essential that when you move ‘off-cycle’ you adjust your diet accordingly. Increasing your protein intake and equalizing your carbohydrate and fat intake will help you keep your muscle mass. There’s no hard and fast rule to this, but just keep in mind that your diet ‘off-cycle’ should not be the same as your ‘on-cycle’ diet.

Training:

In order to bridge successfully, it’s important to stay on top of your training. One way to achieve this is to ensure that when you’re ‘on-cycle’ you focus more on lower weight and higher reps, whilst your off-cycle training should be heavy. Heavier training, when you’re off-cycle or bridging, will effectively build strength and help to maintain the muscle mass you build during your cycle.

In conclusion

All of the above factors are important when bridging with SARMs. To get the most of your cycle, as well as your bridge, each phase requires a subtle balance of all factors to optimise progress as well as health. Be prepared and be well-read. Read our Guide to PCT After Prohormone Cycle to ensure you optimise results, health and recovery.

Dry Gains with M-Sten (25lbs in 4 Weeks)

Insane Dry Gains with M-Sten (25lbs in 4 Weeks)

If you’ve taken an interest in prohormones, there’s no doubt you’ve heard about M-Sten, or Methyl Sten, short for Methylstenbolone, which was first brought to the market as Ultradrol.

Methystenbolone is one of the strongest prohormones on the market which makes it one of the most popular bulking compounds in the prohormone category. Where M-Sten stands out from the rest is the quality of lean muscle gain; its advantage is very little water retention, greater vascularity and definition.

Another advantage of M-Sten is that it doesn’t convert to estrogen. That means no problems “down below”, either with performance or bladder.

Methylstenbolone is banned by WADA so is not recommended for drug-tested athletes.

What are the Benefits of Methylstenbolone?

Gains of an M-Sten cycle are impressive, with a reported lean mass gain of up to 25 lbs in 4 weeks. What you can expect from an M-Sten cycle:

  • Dry gains – minimal water retention
  • Doesn’t convert to estrogen
  • Boosts strength levels
  • Helps promote the development of fuller muscles
  • Considerable size and mass gains
  • Allows you to train longer and harder, which means you get results quicker
  • There are quite a few reports about 3% body fat reduction while gaining as much as 6 pounds of muscle in a 4-week cycle

How to Cycle M-Sten

Gearing up for lean muscle gain means you need to eat more and better than usual; your diet should be on point for best results. Drink lots of water – M-Sten is not liver-friendly. For the same reason, avoid alcohol, that’s the last thing your liver needs on a prohormone cycle. Do it right and you’ll be seeing results in the first couple of weeks.

We recommend 4 weeks on M-Sten initially, and no more than 6 for experienced users.

Depending on your goals, you can adapt your dosages – for cutting, lower dosages work perfectly, whereas for bulking, tapering up the dosage will optimise results. Here are a few protocols you might want to consider:

Newbie Users: 4-week cycle (Week 1-2, 1 capsule per day
, Week 3-4, 2 capsules per day)

Experienced Users: 4-week cycle (Week 1, 1 capsule per day
, Week 2-4, 2 capsules per day)

Advanced Users: 4-week cycle (
Week 1, 1 capsule per day
, Week 2-3, 2 capsules per day
, Week 4, 3 capsules per day)

Do I need to run PCT after a Methylstenbolone Cycle?

Yes. It’s not just your cycle that matters; your Post Cycle Therapy is the phase that makes all the difference. Having a solid PCT protocol will ensure you keep your gains, restore your testosterone levels, balance your hormones and ensure you don’t suffer from those ‘post-cycle blues’. Run your PCT for 4 weeks – we recommend the Mutagenic Labz Regen-T (Total PCT).

Another little-known secret to the perfect PCT is bridging your prohormone cycle with SARMs.

Signs that show you need to pay more attention to your PCT:

  • Feeling tired when you normally wouldn’t
  • Being more aggressive and not knowing why
  • Lower sex drive
  • Back pumps (taurine can help)
  • Joint pain

What are the Side Effects of M-Sten?

It’s not all good news though, but you knew that, right? M-Sten is pretty toxic, to avoid liver damage you’re going to need a quality liver support such as Mutagenic Labz TUDCA Plus.

M-Sten can affect your kidneys too; if you get dark urine while you’re using, that’ll be down to elements that aren’t being metabolized by your body.

M-Sten can also affect your blood pressure and cholesterol, so maintaining a good diet is critical.

Although it doesn’t convert to estrogen, any prohormone will mess with your hormone levels, which means estrogen could be produced because of other factors.

Stacking M-Sten

The Mutagenic Labz Hulk Stack includes M-Sten, Assimilation and Metamorphosiz.

  • Ideal for: Lean Bulking, Cutting/Shredding, Strength, Endurance, Fullness, Huge Pumps, Vascularity, Lean Mass Gain
  • No Bloating or water retention
  • Does not aromatise
  • Highly anabolic
  • Cycle protocol: 4 weeks (8 weeks off)
RAD-140 Advice Before You Buy Testolone

RAD-140 Advice Before You Buy Testolone

RAD-140, also known as Testolone, is selective androgen receptor modulator – or SARM for short. These compounds are gaining a solid reputation within the bodybuilding world as safer and healthier alternatives to anabolic steroids.

RAD-140 began life as a type of testosterone replacement therapy but whether it actually serves as one is disputed.

Similar to other SARMs like S-4 (Andarine) and LGD-4033 (Ligandrol), RAD-140 is known to mimic the results of testosterone albeit without the side effects.
This works because they both focus on the same receptors.

The effects they produce influence muscle and bone tissue as well as the liver.

The Benefits of SARMS

The advantage of SARMs over testosterone is their selective nature. They tend to target muscle and bone tissue over other organs thus allowing SARMs to treat hormone-related and muscle-wasting conditions with less danger of organ damage.

SARMs properties allow them to bind to androgen receptors found in different parts of the body. These receptors are used to interacting with a special group of steroid hormones called androgens. These androgens, testosterone, dihydrotestosterone (DHT), and androstenedione are naturally produced in the body.

Their selective nature means SARMs have become more popular than testosterone or steroids in the bodybuilding world. Because of its testosterone-like properties, RAD-140 is popular for men with lower testosterone levels, but who are unsure of taking traditional testosterone replacement therapy (TRT).

For many, it is another way to amp their physical appearance and increase their sex drive. The compound was also considered as a treatment for muscle wasting conditions and as a potential treatment for breast cancer.

It was developed by Radius Health, a billion dollar ‘Big Pharma’ company, in 2010. Due to its relatively recent inception RAD-140 is the new kid on the SARMS block. The drug is so new that human trials for RAD-140 only began in 2017 and the few results available are somewhat inconclusive.

As it’s not been legally proven to be safe for human consumption and resulting trials haven’t exactly shaken the earth… you might ask, what’s the big deal?
Well, whether the drug proves fit for purpose in a medical sense is a moot point. We all know that Big Pharma is unlikely to approve anything until they’ve found ways to capitalise on the revenue. So it’s with little surprise that in a later iteration RAD-140 found its way onto the bodybuilding stage and right now it’s the new rock and roll.

What Results To Expect From Testolone

The core benefits of Testolone are as follows:

  • Huge increases in lean muscle mass
  • Superior strength gains
  • Supports enhanced strength and explosive power
  • Improved muscular endurance and stamina
  • Fat burning
  • More anabolic than testosterone
  • No androgenic side effects such as male pattern baldness
  • Excellent stacking potential with other SARMs and prohormones
  • Reduced recovery time
  • Increases libido
  • Heightened aggression
  • Increased brain function

RAD-140 is an orally administered SARM designed to seek out, bind to and activate the body’s androgen receptors. This means that in the case of the prostate and breast tissue, RAD-140 blocks AR activation and AR cellular proliferation.

The benefit of this reaction, at least in a bodybuilding senses means that RAD-140 can actively increase bone and muscle mass. This is a powerful aid to any athletes looking to increase muscles mass without increasing androgen levels.
In layman’s terms, RAD-140 is one of the most recognised SARMs for building muscle mass.

In one study scientists were able to use RAD-140 to activates receptors in damaged sections of the brain. The resulting reaction was a signal known as the MAPK pathway which is known to protect brain cells.

Androgens are an important player when it comes to protecting our brains. Tests have proved that androgens have the ability to improve brain cell growth, protect memory, and tackle the underlying cause of Alzheimer’s disease.

How RAD-140 Works

RAD-140 is drawn towards androgen receptors specifically in bone and muscle tissue. Targetting results in the areas we want, this aspect is what makes SARMs so special and ideal for those looking to build lean muscle mass and prevent that muscle from wasting away again.

Once it binds to the androgen receptors, RAD-140 increases nitrogen retention and boosts the synthesis of protein. It’s this reaction that enables users to develop lean muscle.

The good news is that unlike testosterone, testolone is not aromatized or converted into DHT. It also won’t bind to androgen receptors in the prostate or the liver. It’s not known what causes RAD-140 to be so selective, but it’s a moot point as the results speak for themselves.

RAD-140’s structure is unlike that of steroid hormones. The biggest advantage of this is that your body can’t convert it into hormones like oestrogen thus negating the unwelcome side effects. A common problem for anabolic steroid users.

Taken in higher doses, and we’ll talk more about that later, it can also promote fat loss and there are reports it can improve brain function.

RAD-140 Medical Trials: A Tale of Mice and Men

Human trials, as mentioned are currently underway, but evidence from a trial on mice proved the compound to be very successful in increasing muscle.
There’s also a wealth of anecdotal evidence from user studies, almost all of which are overwhelmingly positive.

How To Use RAD-140

Because RAD-140 is a SARM it’s taken orally, usually in the form of capsules or liquid SARMs. The reason for this is simple. Compounds like steroids are not choosy about which tissues they affect, therefore it can be dangerous to ingest them. After all, the last thing you need is a steroid deciding it wants to bind to your heart or other major organs. By contrast, SARMs are selective in terms of binding and will only bind to specific receptors. This means that unlike steroids, which need to be administered directly by intramuscular injection, RAD-140 is safe to take as an oral supplement.

RAD-140 Dosage

RAD-140 is considered to have a similar potency to the compound LGD-4033 which demonstrates solid results from a daily dose of 20/30mg.

Naturally, this dosage is dependent on your size and intended results.
RAD-140 is generally considered to work better for men and some sources go further suggesting that women avoid it altogether.

If you are female and do want to try it then we would strongly urge you to read up on both sides of the argument before going ahead. If you do decide to try it then we recommend a lower daily dose of 5/10mg maximum.

RAD-140 Side Effects

As a new drug, potential users should be mindful of the lack of clinical trials and results. Clearly, this suggests there is insufficient data to establish whether the drug is safe for human consumption. On the flip side of that argument, RAD-140 has seen considerable use in the bodybuilding community. There is, therefore, a wealth of anecdotal evidence from potential users to support this standpoint, but we urge you to draw your own conclusions.

The good news is that neither the few clinical trails nor much of the personal evidence suggests there is much to worry about in terms of ill effects.
One side effect to be aware of and prepare for is suppression; your body’s natural testosterone production is lowered or potentially shut down.

Suppression is triggered by the SARM’s ability to fool the body into thinking it has an abundance of testosterone. Suppression can lead to fatigue, low sex drive and a lack of motivation or aggression.

Other minor reported side effects of RAD-140 include mild headaches, nausea and skin conditions like acne and rashes.

Naturally, the chances of side effects increase with higher doses and staying within safe recommended limits greatly reduces the extent of the side effects you’ll experience.

Reduced Androgenic Side Effects

As a non-hormonal compound, RAD-140 won’t aromatize or convert to DHT. In fact, quite the opposite; RAD-140 can reduce swelling in the prostate gland. This may be due to a side effect of exogenous testosterone. This factor means it’s a good addition to an anabolic steroid cycle.

You may read or hear something about RAD-140 being described as a partial antagonist. This stems from a preclinical characterisation. This might sound like RAD-140 is less androgenic than other SARMs but this is not strictly accurate. The truth is most SARMs are known by the term ‘partial agonist’ in androgen affected tissues, but while RAD-140 is classified in its preclinical profile as a partial antagonist, in certain conditions it can have both properties.

You may, therefore, hear that RAD-140 is the only SARM with antagonistic effects on the prostate gland but that statement is potentially misleading.
All selective androgen receptor ligands have demonstrated partial agonist activity around the prostate. This includes RAD-140 regardless of its preclinical profile.
As a final note, you can play around with this online ovulation calculator and see your most fertile days if you’re trying to conceive a baby.

Does RAD-140 Cause Hair Loss?

Due to its myotrophic/androgenic properties, there is a low risk that RAD-140 could promote hair loss if taken at a sufficiently high dosage.

There are substantial anecdotal reports of users losing hair to RAD-140, but in each case, the reported dosage was far higher than normal.

It should be noted that by adding it to an anabolic steroid stack, RAD-140 could reduce the risk of hair loss.

Does RAD-140 Cause Gynecomastia?

All SARMs carry the risk of gynecomastia (gyno) due to their impact on the Hypothalamus-Pituitary-Testes-Axis. That said, the risk is much lower with RAD-140.

Suppressing testosterone production is enough to cause a hormone imbalance and such an imbalance may be enough to trigger gynecomastia development.
If in doubt also seek professional medical advice.

RAD-140 Vs Anabolic Steroids

RAD-140 is often considered the next best thing to steroids, at least in terms of results. There are multiple reports of huge lean muscle and strength gains and even some suggestion that it can help burn fat at the same time.

In terms of practicality, there really is no competition, despite the fact testolone hasn’t been around long it has already proven itself to be a viable alternative to traditional steroids. Not only is it non-specific and therefore safe to take in oral form, but RAD-140 also has most of the upsides of anabolic steroids and practically none of the downsides (except suppression).

There are no reports of testicular reduction or an enlarged prostate. Indeed, the most significant complaint is that it may cause a reduction in testosterone levels.
RAD-140 is renowned for its potency and as a result reports of dramatic results are commonplace.

There is some anecdotal evidence to suggest the anabolic to androgenic ratio of RAD-140 is as high as 90:1. It is this huge swing that allows the compound to deliver enormous muscle mass and it’s not unknown for users to gain 10lbs+ of lean muscle from one cycle.

RAD-140 Vs Testosterone

As mentioned, the compound was at least partially developed as an alternative to Testosterone. It makes sense that they share a number of properties, although one study highlighted an interesting difference.

In tests it was discovered that taken alongside anabolic steroids, RAD-140 was able to reduce the side effects of testosterone. It’s not known exactly why this phenomenon occurred, but it’s likely that it’s related to RAD-140’s inability to aromatise or convert into DHT. Either way, the results seemed conclusive.

What Results to Expect from Testolone

Despite the lack of official trial data, there is a wealth of information available from private users of Testolone. We’ve researched most of the reports thoroughly and what follows is a condensed version of our findings:

Increased muscle mass

An early animal trial on RAD-140 demonstrated an average weight gain of more than 10% over a 28 day period. This was achieved using a stand-alone low dosage of RAD-140. Researchers noted no adverse side effects, even those traditionally associated with testosterone

Strength gain

One of RAD-140’s most attractive properties is its ability to make you stronger. Over the course of a 28 days cycle, the effects are noticeable from as early as two weeks in. Lifts will become easier and your sets will feel more intense. You’ll break records, set new benchmarks and best of all these effects will last.

Increased bone density

As with all other SARMs, over time RAD-140 will improve the mineral density of your bones. You may even find that the compound prevents and aids recovery of previous bone injuries.

Stamina, speed & endurance

RAD-140 has gained a lot of fans in the bodybuilding community, many of whom report significant increases in all of the above.

Aggression

Aggression, focus, call it what you will, when it comes to RAD-140 you will notice a clarity of mind far beyond your daily norm. This ‘aggression’ should not be confused with ‘roid rage’ and although there are limited reports of irritability at the early stages you’re unlikely to feel the need to let rip anywhere other than the gym. It’s a good idea to make sure you focus on getting enough sleep.

Less apathy

One universal report about RAD-140 is the compound’s elixir-like quality. You’ll bounce out of bed, spend the day on top of the world before bouncing back in again.

How To Cycle RAD-140

Testolone, or RAD-140, is best taken in six to twelve-week cycles followed by a course of PCT (Post Cycle Therapy).

In the short term

In the first couple of weeks, RAD-140 users will begin to feel physically stronger. This due to the compound’s ability to help the body build muscle. This increased strength will allow you to train harder and longer and in turn build even more muscle.

Midway

Halfway into your cycle, you should start to see a significant physical change. Increase weight, visible muscle growth and naturally, you’ll be able to train even harder now.

Two Thirds In

Throughout the process, you will continue to gain weight and strength and if your dose and program are on target, you can expect to see gains muscle mass gains anywhere between 10 to 15 lbs (4.5 to 7.5 kg).

Does RAD-140 Require Post Cycle Therapy (PCT)?

Almost all supplements can suppress the body’s own innate ability to create certain chemicals. In the case of SARMS, this usually equates to an inability to produce testosterone. As mentioned above, an eight-week cycle is sufficient to make measurable gains from RAD-140 and we strongly urge you to follow this with a rigorous period of PCT.

The best way to do this is to take both Clomid and Nolvadex to bring the body’s hormone levels back in balance. We advise a four-week course of PCT after each RAD-140 cycle. This will also depend on the dose.

Stacking RAD-140

Testolone stacks well with most other SARMs and prohormones. Despite the lack of clinical trials it appears to be a safe bet when it comes to supplements and this means it’s safer than most to stack alongside others. Stacking reports are of course entirely anecdotal and you’ll need to use your own judgement to decide whether stacking it right for you. There have been some positive reviews from users stacking Testolone with YK-11.

The key takeaway noted from most of these reports is that the stacks appear to significantly improve the acceleration of the muscle building effects. Best results were posted by those taking the stacks on a two to one ratio. That’s twice as much RAD-140 as YK11 (for example, 20mg Testolone v’s 10mg of YK11). This stack alleges tangible muscle and strength improvement in just three days.
Other SARMs with positive reported results, when stacked with RAD-140, include Ligandrol and Ostarine. Again these stacks appear to amplify the effect of both compounds.

RAD-140 Price and Availability

RAD-140 is readily available on the market but it’s worth remembering that the SARMs and supplement market can be a lawless place. Therefore it is a good idea to source your supply from a reliable source and not from the back of the gym.

Naturally, we provide an excellent range of RAD-140 products with independently tested Certificate of Analysis (CoA) documents to reassure you of what you buy, but there are others out there too, just be sure to avoid the black market.

Testolone is not the cheapest SARM on the block, but as the drug becomes more accepted in the mainstream you can expect to see the price fall. For now, however, many users consider its price point acceptable, especially considering the achievable results.

Other Important Factors

Bioavailability

RAD-140 has good bioavailability. Research gleaned from primate tests suggested an absorption rate in the 70% region.

Half-Life

The jury is somewhat out on the half-life. Much will depend on the purity of your source but reports indicate that the average half-life of RAD-140 sits around the 18-hour mark. If this figure is accurate, and we believe it is, then taking Testolone once per day should provide the desired results.

Legality

As with most SARMS, there is a legal grey area surrounding Testolone. It is not an illegal substance but it is worth noting that SARMs are banned by WADA and in most sports – it is listed on the World Anti-Doping Agency’s prohibited list.

In conclusion

Miracle elixirs and potions of youth are common phrases in the bodybuilding world. With a little research and some closer examination, however, these magical cure-alls are more often than not little more than glorified snake oil.
Testolone or RAD-140 holds up to closer scrutiny better than most.

At the end of the day, we have to conclude that despite its chequered past in the Big Pharma world, RAD-140 does appear to have much to offer the bodybuilding world. You’ll want to make sure you keep within the guidelines and always be prepared to seek professional medical advice if things go south.

Due Diligence and Disclaimers

We have done our best to present an honest and open article on the pros and cons of RAD-140. It should be noted however that this article is our opinion only. We are not trained medical professionals and make no claim to be so. It is our aim only to provide information to allow the reader to make up their own mind on whether this drug is for them or not.

All claims and statements in this article are true to the best of our knowledge. While it is true that this drug is an untested substance and banned in most sporting events, we believe there is sufficient anecdotal evidence to suggest it’s not only safe to use but can offer much in the way of rewards.

After all, if we relied on big pharma to decide what’s safe, we’d end up with zero cures, wealthy chemists and a never-ending stream of expensive treatments.
So, decide for yourself if Testolone is the SARM is for you.

LGD-4033: Amazing Benefits of Ligandrol

LGD-4033: Amazing Benefits of Ligandrol

Hailed as the ‘King of SARMs’, LGD-4033, also known as Ligandrol or LGD for short, is quickly becoming the SARM of choice for bodybuilders, weightlifters, crossfitters and even fitness models. In the bodybuilding world, SARMs are often used as a safer substitute for anabolic steroids. SARMs have many of the advantages of steroids without the nasty side effects but the purpose for taking them both remains the same; to enhance fat loss while building muscle, to improve performance and strength, as well as to promote healing and recovery.

See our guide to Bridging Prohormone Cycles with SARMs.

Dropping fat while you’re trying to increase muscle mass seems counter-intuitive and with good reason. Biology doesn’t like the idea in general, so if you’re trying to achieve this effect you’re going to need some help. Ligandrol is probably the most effective. It’s taken orally and was developed to combat muscle-wasting conditions and osteoporosis.

How Does LGD-4033 Work?

LGD-4033 binds itself to targeted androgen receptors in muscle tissue. It is this selective nature which allows Ligandrol to be taken orally rather than by injection. Because of its selective nature, LGD-4033 naturally avoids major organs which makes it a lot safer than some of the alternatives and especially steroids.

LGD-4033 increases the body’s testosterone levels, which promotes muscle growth, improves the amount of energy produced by the body and generally boosts blood circulation. There has been some suggestion that LGD-4033 also improves bone density which would make sense considering its potential as a treatment for osteoporosis.

The Benefits of Ligandrol

The many benefits of Ligandrol reflect its extremely popular status as one of the best SARMs on the market today:

  • Promotes lean and dry muscle mass gains
  • Sustainable results, even at lower doses
  • Boosts fat loss
  • Increases libido
  • Increases stamina and endurance
  • Promotes recovery
  • Considered the best SARM for bulking amongst many
  • Ideal for body recomposition (losing body fat whilst gaining muscle)
  • Stacks brilliantly with Cardarine for effective cutting cycles
  • Gives amazing pumps and fullness
  • Increases cardiovascular strength by week 3
  • Gives a heightened sense of wellbeing without mood swings or crashes
  • More powerful than Ostarine
  • The closest SARM you can get to testosterone
  • No bloating or water retention
  • No male-pattern hair loss
  • No liver damage
  • No changes in cholesterol or blood pressure

LGD-4033 Increases Libido

SARMs are selective in their nature but they also affect the brain and offer a host of cognitive benefits. This explains their positive effects on libido and mood enhancement. There have been many anecdotal reports supporting that LGD4033 can greatly improve cognition, libido and energy; most users report an increased sense of wellbeing and stamina when using this SARM.

Ligandrol Side-Effects

Ligandrol is still new and there hasn’t been a great deal of research on it. The few studies that do exist suggest the SARM is easily tolerated by the body and few if any side effects have been recorded.

The studies and other anecdotal evidence does suggest that users will experience very slight suppression. In most cases, there is no need for a PCT but some may prefer to run a mild over-the-counter PCT supplement and a Testosterone Booster to optimise natural testosterone levels post-cycle.

LGD-4033 doesn’t increase estrogen levels so there is no risk of man boobs, puffy nipples or water retention.

Although safer than some of the other SARMs on the market and clearly safer than steroids, there is some anecdotal evidence to suggest that Ligandrol can cause headaches and nausea.

Dosage

The few studies that have taken place suggest that doses as low as 1mg per day are enough to have a significant effect on muscle growth and that doses as high as 25mg showed little, to no, side effects.

An entry-level dose of 5mg per day rising to 10mg if you’re on the heavier side. The results that have come in suggesting that a cycle of 2-3 weeks is enough to cause a significant effect but 4-8 weeks is ideal.

How to Take LGD-4033

The half-life of LGD 4033 is 24–36 hours, therefore it can be taken just once per day. Keep in mind is that its long half-life means that the levels of LGD-4033 will gradually build up in your system over the course of your cycle. Studies showed that blood levels nearly tripled after 3 weeks compared to the first day.

While most SARMS are often stacked together for optimum results, a lot of users see great results with LGD-4033 as a standalone. Stacking Ligandrol works best with MK-677, Cardarine, Ostarine and Testolone RAD-140.

In conclusion

LGD-4033 is a potent yet safe SARM that stacks well with other SARMs, prohormones and supplements, and the fact it can be taken orally is a bonus.

Fat Burners that Actually Work

Fat Burners that Actually Work

When you want to get into the best possible shape, fat burners can give the extra edge you need when everything else is in place. If your diet, training and recovery are refined, adding a little extra something might just be the push that you need. Here we’ll take a look at how these supplements actually work, how to use them effectively and their main benefits.

Fat burners are designed to do precisely what their name suggests – target and mobilise fat cells, to burn fat more rapidly. If you’re carrying more weight than you’d like in the form of fat, these nutritional supplements increase energy expenditure and fat metabolism while impairing the absorption of fat, boosting weight loss and increasing fat oxidation while you exercise. So, let’s take a closer look at how these supplements work for your benefit.

How Do Fat Burners Work?

There are several ingredients in fat burners which will stimulate a hormonal reaction in your body to break down fat and use it as a source of fuel. They cannot work effectively on their own, however; you have to eat a healthy diet designed for bodybuilding so that the fat burner can work to its maximum effect. When you eat for fat loss, you’ll find that these supplements help your body to burn extra calories all day long.

What Are Reasonable Expectations From a Fat Burner?

Although fat burners are scientifically proven to work, it’s important to have a reasonable expectation of what these supplements can achieve. They won’t melt an enormous amount of fat every week. However, you can enhance the rate at which you lose fat. It’s considered safe to lose around 1 to 3 pounds every week. If you lose weight more quickly than this, you run the risk of losing lean muscle mass – disastrous in bodybuilding terms.

Start Out Low

Although fat burners are specifically designed to support your fat loss, taking a larger amount of them won’t give you greater results. Make sure to check out the serving guideline so you can measure out the correct dose for your needs. Start with the lowest dosage on the packaging for a couple of weeks before increasing your serving.

How To Cycle Fat Burners

No fat burner will give results continuously. When you use them over an extended period, your tolerance level will go up and they will stop working as effectively. This is why cycling your fat burner supplement is so important. Use your fat burner for around 4 to 6 weeks and then take a break for a couple of weeks before recommencing taking the supplement at a lower dose.

Optimise Your Training

When you’re using fat burners, make building muscle your priority. You need a training programme which will maximise your fat loss at the same time as minimising the amount of muscle you lose. This will ensure you maintain a healthy body composition while boosting your muscle growth.

Don’t Cut Too Many Calories

Although you should consume fewer calories than you manage to burn, going too low is always a mistake. Restricting your calorie intake won’t lead to predictable weight loss and it certainly isn’t a sustainable or healthy way to shed fat.

Take Care With Stimulants

Some fat burners contain stimulants while others do not. Products which have a high caffeine level will make you feel energetic, but they can disturb your sleep quality and that can lead to higher fat gain. It’s important to choose the right product for you, and if you drink a lot of coffee or take other stimulants, it’s usually best to choose a stimulant-free fat burner.

Our best selling stimulant-based fat burner is Yamamoto® Nutrition Ai-BURN®. This premium quality fat burner is a dietary supplement that assists a calorie-controlled diet for optimal fat loss. Thanks to its plant extracts, the product promotes a stable body weight (Green Tea) and metabolic stimulation, particularly of lipids (Bitter Orange). Moreover, cocoa extract supports metabolism and plays a tonic function.

Stimulant-Free Fat Burners

If stimulants aren’t your thing, there are non-stim options such as the MyoBlox Rubix Fat Burner. Rubix™ works on multiple facets of fat loss to aid in improved metabolism and fat utilisation without caffeine or any other stimulant. It boosts metabolism and regulates insulin levels, suppresses appetite and supports fat loss from multiple pathways.

The Olympus Labs Assassinate is another best-selling non-stimulant fat burner that helps to reduce your appetite, prevents the storage of new fat cells and stimulates your metabolism. Assass1nate also doubles as a glucose disposal agent, which helps you to utilize your food as fuel instead of storing it as fat, especially your carbs. So make sure to take it with your carb-heavy meals.

What are the Best Fat Burners?

There are a number of ingredients found in fat burners, however, SARMs have been found to be some of the most effective compounds for fat loss on the market.

Similarly, PPAR-delta activator Cardarine can boost your body’s fat-burning capacity by stimulating glucose and activating the ABCA1 and CPT1 fat-burning genes, which shows superb results such as this human study on Cardarine’s potential for receding fatty acids, VLDL proteins and triglycerides.

Another highly effective compound often used for shedding the fat is Stenabolic SR-9009. Often categorised as a SARM, Stenabolic is a REV-ERB agonist that shows a considerable boost in fat-loss and endurance.

MK-677 (Nutrobal) is also very effective for fat loss but some may suffer from an increased appetite for the first week or two, so discipline is critical.

Summary

There are many excellent fat burning supplements available to help you achieve your bodybuilding goals, but always make sure to buy from reputable online retailers to ensure that you are getting the high-quality product that you’re paying for.

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