Fat Loss | Blog Posts on Fat Loss

22/05/202223/05/2022

Best SARMs Stack for Cutting (Updated 2022)

SARMs are getting increasingly more popular amongst bodybuilders, competitors and athletes, so one of the most common questions we get is to recommend the best SARMs stack for cutting. It’s not surprising when you consider that these compounds can help build muscle, give a denser, harder look to muscle and help burn body fat beyond our natural potential.

That’s the holy grail – adding mass and not losing it again when you diet! Not to mention, to speed up the process of losing body fat and revealing those chiselled abs!

Which are the best SARMs for fat loss? Here’s our take on it…

What Are SARMs & How Do They Work For Dieting?

SARMs are “selective androgen receptor modulators”, compounds which selectively bind to androgen receptors in the body’s tissues to help manipulate our natural hormone levels. Androgens are hormones which signal the body to make changes – like the way testosterone signals the body to grow.

By binding to some of the receptors which receive these hormonal messages, SARMs can specifically boost some of those signals. The key here is in the “selective” part of the name. SARMs don’t bind to every receptor (unlike anabolic hormones, which do). They only bind to receptors in bone tissue and muscle tissue. This selective nature means you get more specific in what you want the SARM to do, and you can avoid a lot of the side effects associated with steroids.

Most SARMs were initially developed as a possible way to create certain medical conditions, specifically those related to loss of bone density, muscle mass, and strength. They caught the eye of researchers because they were able to bind only to the affected tissues, and not to anything else like internal organs.

SARMs can be taken as orals which makes them easier and more user-friendly than anabolics.

But what about using SARMs for fat loss? In this article, we will look at how to use SARMs for cutting (fat loss dieting) whether you want to do that for your health, your appearance, or as a bodybuilder.

The Best SARMs for Cutting

In order to put together the best SARMs stack for cutting, we’ll take a look at the different SARMs that are best for fat loss, and the reason why they make a good choice for your dieting phase.

Each of the different compounds below has superb fat-shedding qualities and these are often interchanged depending on the preferences of the individual user. In short, the best SARMs stack for cutting is the one that works for you! See which compounds fit your preferences and do your research – that is always the best way.

Andarine S4

Andarine, or S4, is a strong and potent SARM which is thought to increase fat oxidation and reduce lipoprotein lipase which is linked to fat accumulation in the body. Initially developed to combat conditions such as osteoporosis and muscle wastage, S-4 is one of the most researched SARMs which is always a positive aspect.

Andarine also helps increase muscle mass and strength. Even low doses of Andarine can help you maintain all your gains when you go into a calorie deficit to get lean. All in all, a good choice for cutting or body recomposition.

Best dose: start at 25mg/day split into 2-3 doses (4-6 hours apart), never go higher than 50mg/day and keep cycles to an 8-12 week maximum.

Ostarine

Ostarine MK 2866 really helps boost muscle gain because it increases the body’s levels of nitrogen and protein. This makes it a good choice for protecting muscle mass when you diet, avoiding that stringy, over-dieted look.

LGD-3303 (Not LGD-4033!)

A quick update here: LGD-3303 has now been patented by pharmaceutical company Ligand Pharmaceuticals Incorporated and is no longer available on the market.

LGD-3303 is a potent and highly selective androgen receptor full agonist in skeletal muscle, a classic target tissue for androgen action. By comparison, in the prostate and sebaceous glands, the compound is a weak partial agonist. The sparing of these non-target tissues by effective, pharmacologic doses of LGD-3303 provides a novel and potentially safer treatment for osteoporosis.

Source: Ligand Pharmaceuticals Incorporated

Released September 17, 2007

Here’s where our recommendation on the best SARMs stack for cutting is different from any other you may have seen online. Most will recommend Ligandrol but we beg to differ. LGD-3303 is the leaner, dryer, fuller and more vascular successor of Ligandrol (LGD 4033). For that reason, it undoubtedly takes the throne.

Cardarine

Cardarine GW 501516 isn’t actually a SARM but a PPAR gamma receptor agonist that binds to PPARδ receptors instead of androgen receptors like a SARM normally would.

Cardarine supports healthy cholesterol levels and increases your basal metabolic rate, which helps your body to burn more energy (aka fat) even when at rest. You might also feel an energy boost, which definitely helps when you are dieting in a calorie deficit! Cardarine is a compound we stack with pretty much anything; this one’s a winner all-round… even when bulking to mitigate fat gain.

Stenabolic

Stenabolic SR 9009 is another on this list which isn’t actually a SARM (it’s a REV-ERB agonist) but it deserves a place on this list. As a REV-ERBα agonist, it can help manipulate certain functions relating to the metabolism, so you feel more energised, burn more stored fat, and get a boost to your metabolic rate even at rest. Stenabolic is also a compound we love to stack with pretty much anything.

MK-677

MK-677 is a growth hormone secretagogue and stacks well with virtually anything. It is a very versatile compound that can be used for both bulking or cutting, depending on the accompanying diet and training plan (increased calories will support bulking and reduced calorie intake supports fat loss).

Glucose Disposal Agents

Although Glucose Disposal Agents aren’t SARMs, they deserve a mention. Nutrient partitioning often gets forgotten about but is so effective when it comes to body composition. A glucose disposal agent decreases the amount of insulin secreted by the body when eating a high-carbohydrate meal and shuttles glucose into muscle cells instead of storing them in fat cells. This results in reduced fat gain and a potential increase in lean muscle gain.

The Best SARMs Stack for Cutting

As we’ve already pointed out, you can stack different SARMs to assist you during a cut and there are different ways to mix and match the compounds that work best for the individual.

One of the best SARMs stack for cutting we’ve researched is for the more advanced and experienced:

Andarine S-4 – 50mg per day, 25mg in the a.m. and 25mg 4-6 hours later
Ostarine MK-2866 – 20mg per day, dosed once a day in the a.m.
GW/SR (SR-9009/Cardarine Blend) – 1 capsule in the a.m, 1 capsule in the p.m.
MK-677 – 20mg per day, dosed once per day (can be reduced to 10mg if appetite increase is unmanageable).

5 Keys To Getting Shredded

Remember that there are several aspects to getting that lean, shredded look. Sure, you need to reduce your body fat. But you also want to increase muscle mass, and – crucially – retain as much muscle as possible even as you diet to lose fat. It’s a difficult task, but SARMs can make it much easier.

1 A calorie deficit

You need to be in a calorie deficit to lose body fat, it doesn’t matter what kind of diet you follow – a calorie deficit is crucial. This means making sure your total “calories out” are higher than your “calories in”

2 Sufficient protein intake

Eating enough protein will help you build muscle, maintain muscle, and it will help keep you feeling fuller (protein has the highest Thermic Effect Of Food of any macronutrient) which will help diet compliance

3 Training frequency

We now know that training frequency is the most important factor in muscle gain and muscle retention, ideally train each major muscle group every 72 hours

4 Load and volume

Within that training, you need to put enough load (weight) and volume (weight x sets x reps) through the muscles

5 Appetite and energy management

Get control of your appetite, eating habits, and your energy output to increase your success with getting super-lean and shredded!

What’s the Best PCT for SARMs?

Although PCT is a very subjective matter, it’s often recommended to run a PCT such as Pro PCT (6-OXO).

Pumping Iron Pro PCT (6-OXO) is an advanced SARMs and prohormone PCT that contains 6-OXO, a potent aromatase inhibitor which should only be used by experienced users of SARMs and prohormones. This supplement is intended for male athletes only and shouldn’t be used by women. PRO PCT can be used to prevent estrogen related side effects on-cycle as well as a powerful recovery agent for post cycle therapy (PCT)

Strongest aromatase inhibitor on the market
Increases lean muscle mass
Reduces conversion of testosterone to estradiol
Supports muscle retention
Increases testosterone:estrogen ratio
Suitable for vegans (HMPC Veg Cap)

13/02/202108/03/2021

In Fat Loss, Prohormonesby Nicola Joyce

Best Prohormones for Cutting (Updated 2021)

The best prohormones for cutting and getting shredded are those that don’t cause water retention and provide the chiselled, well-defined physique throughout the cycle.

Getting lean and shredded is one of the most popular goals on the gym floor. Every guy wants to get super-lean at least once in his life. And when you decide to do it you’ll want to go all out. After all, there’s no point grinding through a diet and doing extra cardio if you’re only going to get mediocre results at the end of it.

If you’re planning your next cut, you might be wondering whether SARMs or prohormones could help you get that bit leaner than before…

The answer is yes, there are compounds out there that can help you burn more fat, get leaner and – crucially – hang on to muscle whilst you melt away fat.

What are the best prohormones for cutting? Let’s find out.

What Are Prohormones?

Pro hormones are different from SARMs and they are definitely not anabolic steroids either. Prohormones are really “pro-steroids”) because they act as precursors to anabolic growth hormones in your body, encouraging your body to churn out more of those muscle-building, fat burning, strength gaining hormones.

Are Prohormones Legal?

You need to do your research about the legality of prohormones (which is why you’re here!) In the USA, a lot of prohormones were banned under the 2014 Designer Anabolic Steroid Control Act of 2014 in the USA. That said, a few remain outside of this ban. These currently include:

1-Androsterone (1-DHEA or 1-androstene-3b-ol-17-one)
4-Androsterone (4-DHEA or 4-androstene-3b-ol-17-one)
1,4-OHP
Epiandrosterone (Epi-Andro)
6-Keto-progesterone

And do remember that all prohormones are banned by WADA, so if you are planning on doing any tested competitions – included natural or drug-free bodybuilding contest – you won’t be able to use prohormones at all.

How Do Prohormones Help You Get Leaner?

If you are thinking about using prohormones on your next cutting diet, you will want to know exactly how they would potentially help. The best prohormones for cutting and getting shredded are those that don’t cause water retention and provide the chiselled, well-defined physique throughout the entirety of the cycle.

As you know, there are a few factors that lead to some dropping body fat, retaining muscle and rocking that lean, full look.

1 Losing body fat.

The key to this is a calorie deficit, but anything that helps boost the metabolism and hang on to lean muscle will help. Prohormones can do both those things.

2 Energy output

The more energy you can burn (as long as you don’t overeat to compensate!) the more fat you’ll lose. Prohormones can give you an energy boost and training endurance.

3 Training intensity

You need to lift heavy and often to burn fat and keep muscle on in a diet. Prohormones give you the energy and drive that you need to train through a deficit.

4 Muscle retention

The more muscle tissue you can retain on a diet, the better you’ll look (and the healthier your metabolic rate will be). Prohormones can help you keep hold of more muscle.

Prohormones act as a precursor to the hormones testosterone and dihydrotestosterone, encouraging your endocrine (hormonal) system – including your pituitary and thyroid glands – to use this excess of anabolic hormones to build more muscle.

The Best Prohormones For Cutting

Here are the three most popular and effective prohormones for rapid fat loss on a cutting diet.

Mutagenic Labz Mutation-X is a potent blend of Trenavar and SD Matrix which is highly anabolic and promotes serious levels of protein synthesis. Each dose has 10mg Trenavar (also known as Estra-4,9,11-triene-3,17-dione, or Trendione), 10mg SD Matrix, plus 5mg Piperine. This blend combines two of the best prohormones for cutting in one product.
Pumping Iron M-Tren gives amazingly dry, lean gains in muscle mass so you can expect at increasing strength and visible physique changes, no bloat, no water retention and full muscles. Great for a body recoup or cutting cycle.
Mutagenic Labz M-Sten is highly anabolic and best for experienced prohormone users. It’s the purest Methylsten product you’ll find (at least we think so!) Each dose delivers 10mg Methylstenbolone plus 5mg Piperine. Expect dry, hard muscle gains, fast fat loss, amazing pumps and a full lean look to your physique.

When you’re supplementing with prohormones, it’s important that you use the right product depending on your goals. The best prohormones for cutting are considered ‘dry’ compounds.

Prohormones fall into two main categories; wet and dry. A ‘wet’ compound will cause you to retain water during the cycle and generally be bulkier, which aids muscle protein synthesis (these prohormones are usually more potent than the dry compounds). This is great if you’re bulking but not so much if you want visible abs.

The other options are ‘dry’ compounds. These compounds will cause you to shed water and will often increase muscle hardness and fullness, as well as density and vascularity.

Stacking Prohormones

You can stack prohormones or just get the blends such as the Mutagenic Labz Mutation-X mentioned above which has done the lab work for you. Unless you are an advanced user, we don’t think it’s worth the risk of working out your own stack when you can buy a combined product that has already been created by experts.

If you’re ready to stack, we would recommend stacking Androtest and one other product.

When stacking prohormones, bear in mind that you do not need to run the products at full doses as you would if taken alone.

Prohormone Side Effects

You wouldn’t take any medication or drug without checking potential side effects, would you? So the same goes for prohormones.

Some people report increased blood pressure, acne, hair loss, liver stress, or reduced HDL cholesterol from prohormone use.

We think the best way to try and avoid any of this is by purchasing quality, trusted products (rather than trying to stack your own), always sticking to the dosage recommendations, never running a super-long cycle and always doing a PCT and natural testosterone booster afterwards to look after your health.

How To Take Prohormones For Dieting

If you buy prohormones from a trusted source, you’ll also be getting the best advice about doses and cycle length. Stick to this advice, don’t be a hero and just rely on the product to do its job.

Remember, even prohormones can’t help you lose fat if you aren’t also dieting. They’re not a magic pill (although they might feel like it!) so be sure you have your diet in check, your training is intense and regular and you stay active with a good step count or extra cardio if you have a sedentary lifestyle.

What’s The Best Cycle Support for Prohormones?

As with any pro-hormone, long term use of prohormones could have adverse effects on your liver, so you should use cycle support such as TUDCA.

The Pumping Iron TUDCA is a state of the art liver detox product that works perfectly as a detox product alone or alongside a prohormone cycle. A crucial aspect to successfully running your prohormone cycle is preserving your best health, so you can feel well in your body and revitalised after your post cycle therapy to enjoy your new-found strength and results in the long term.

Protects the liver and restore natural bile acid production
Dissolves dietary fats so that they can be more easily broken down by lipases
Enables absorption of fats and fat-soluble vitamins A, D, E, and K in the gut
Protects the gut from infection by stimulating the gut immune system
Break down and eliminate cholesterol gallstones
Removes excess cholesterol
Eliminates Bilirubin from the body
Digests proteins and starches
Removes toxins from the body
Protects the gut from infections
Reduce anxiety and promote sleep
TUDCA is vastly more superior to Milk Thistle

What’s the Best PCT for Prohormones?

After taking pro hormones you should run a PCT such as Pro PCT (6-OXO).

Strongest aromatase inhibitor on the market
Increases lean muscle mass
Reduces conversion of testosterone to estradiol
Supports muscle retention
Increases testosterone:estrogen ratio
Suitable for vegans (HMPC Veg Cap)

Stenabolic SR9009 - The Secret Fat Loss Wonder Drug

25/01/202108/03/2021

In Fat Loss, SARMsby Nicola Joyce

Stenabolic SR9009 – The Secret Fat Loss Wonder Drug (Updated 2021)

We write about SARMs at Pumping Iron Store but this is something a little different. Although you will often hear Stenabolic SR9009 talked about in the same conversation as SARMs, it is not, in fact, a SARM. This article will tell you about Stenabolic, why it was developed, what it is, the benefits and side effects and what to expect.

Although Stenabolic SR9009 was developed to study the circadian rhythm, studies have shown this drug to improve the overall health and quality of life of anyone who uses it. Dubbed as ‘exercise in a bottle’, research on Stenabolic shows that it can help to lose weight, decrease cholesterol, inflammation and even anxiety.

What Is Stenabolic SR9009?

As we have briefly mentioned, Stenabolic is not a SARM. It is a compound that was developed by researchers in a bid to treat or manage medical conditions. Stenabolic is a REV-ERB (specifically a REV-ERBα antagonist) which means it impacts the metabolism, including the circadian rhythm. It’s pretty complicated to explain, but here’s our best layman’s version:

Your body’s circadian rhythm is a pattern your system cycles through every 24 hours. Experts think it is linked to sunrise and sunset. It governs things like sleep, waking, energy levels, and hunger. Part of the cycle that keeps your circadian rhythm going involves “switching” genes on and off throughout the 24-hour cycle.

Stenabolic was initially developed for its effects on the circadian rhythm and was found to improve mood, control anxiety, reduce inflammation, and even have a positive impact on weight gain. Sounds good for bodybuilding, right?

Stenabolic was also found to increase the activity of REV-ERB nuclear hormone receptors, and this boosts the bioavailability of nutrients in your body. For us as bodybuilders, this means better nutrient uptake and more of the nutrients we eat gets to our muscle tissue.

One thing you must consider about SR9009 is that there is no human research on it. There’s plenty of research from animal studies (especially mice studies) but none on human subjects. There is plenty of anecdotal evidence and feedback from guys who use it to augment their training. So be sure to go into this with your eyes open and full awareness of the lack of human research.

How Does Stenabolic SR9009 Work?

The processes behind SR9009 are pretty complicated and well beyond a short article here. If you’re the deep-dive research kind of reader, take a look at this paper published in Nature Reviews Drug Discovery in 2014 or this 2016 paper published in the International Journal of Molecular Sciences.

SR9009 has a significant impact on REV-ERBA, which impacts circadian control and has knock-on effects on the immune system, sleeping patterns, energy production, and general activity.

Activation of Rev-ErbA-α by SR9009 increases exercise capacity by increasing mitochondria counts in skeletal muscle.

REV-ERB is particularly influential in the tissues of the muscles, body fat, and liver. This suggests it could help boost fat burning, “switching off” the genes which store fat and increasing the number of mitochondria in the muscles.

OK, that’s a lot of scientific talk (and a couple of papers for you to look at). But what about the real-life stuff – how does SR 9009 benefit bodybuilders and people who want to get big, ripped, and lean?

Benefits of Stenabolic SR9009

Increases oxygen consumption
Prevents the creation of new fat cells in the liver
Increases the number of mitochondria in the muscle cells
Increases glucose and lipid metabolism
Decreases triglyceride levels in the blood
Reduces cholesterol breakdown in the liver
Promotes fat loss through glucose consumption
Regulates blood sugar levels
SR9009 has even been used to treat type-2 Diabetes
Delays the ageing process
Reduces inflammation
Decreases anxiety

1 Weight loss & fat loss

SR9009 has been shown to increase weight loss even without altering dietary intake. It has also been shown to reduce amounts of free fatty acids, triglycerides, and cholesterol. It could be great as a fat burner when you’re dieting or trying to get rid of that last bit of body fat.

2 Mood & energy

SR9009 is thought to be able to affect sleep patterns, which is beneficial to recovery and general health. It has been shown to increase energy levels and could even be used to increase wakefulness. Some studies also suggest SR 9009 could reduce anxiety.

3 Endurance

SR9009 has been shown to increase the total amount of mitochondria, which has a direct impact on endurance levels for physical activity. More endurance = more training = more gains.

4 Reduced inflammation

Inflammation can pose a big problem for bodybuilders who train hard, and Stenabolic SR9009 may be able to tackle this issue (by reducing TNF alpha in the body – these cells are a key player in systemic inflammation).

Does Stenabolic Have Side Effects?

We don’t know of any side effects with Stenabolic SR 9009 but there haven’t been any human studies so it’s difficult to say this with total confidence.

Stenabolic has shown no liver toxicity.

However, we do know that SR9009 doesn’t impact the body’s natural hormone levels so you won’t need to run a PCT if you use Stenabolic.

Best Dosage & Cycle Length for Stenabolic

Stenabolic has a half-life of 4 hours so you’ll need to split your total daily dose into 2-3 doses per day. So, if you’re taking 20mg/day, take 5mg every 4 hours (say, at 8 am, 12 pm, 4 pm, 8 pm).

Start at 10mg-20mg/day (maximum) and increase only to 30mg if you need to.

Most will run Stenabolic SR9009 cycles of 8-12 weeks, followed by the same time off.

Does SR-9009 Require a PCT?

Stenabolic (SR-9009) is not suppressive and does not generally require a PCT.

19/09/201929/09/2019

In SARMs, Fat Lossby Nicola Joyce

Cardarine Review: Your Guide To GW-501516

Read our Cardarine review to understand what it is and why it seems to be shaking things up in the bodybuilding industry! What exactly is Cardarine and what are the benefits for muscle gain and fat loss?

Cardarine (also known as GW 501516) is a very interesting compound that you might have seen cropping up more and more in the bodybuilding and fitness community recently. It is often referred to as a SARM, mainly because it’s often found in the same category as other SARMs and often stacked alongside them. GW actually a PPAR-delta activator. In this article, we discuss what this means, how GW501516 works and why many bodybuilders are turning to Cardarine to help them gain muscle, lose fat, improve their physique and train harder in the gym.

What is Cardarine GW 501516?

Although some people call Cardarine a SARM, it is not actually a selective androgen receptor modulator. Cardarine is actually a PPAR-delta activator but it works in similar ways to a SARM and that’s why bodybuilders and gym trainees are attracted to it for muscle gain, strength gain and fat loss.

Cardarine was originally developed as a potential medical asset for prevention of tumours but it soon showed other benefits: it could help reduce body fat, control body weight, raise the metabolic rate, increase rates of muscle growth, and boost endurance. No wonder bodybuilders are keen to take a closer look!

Like all drugs of its type, Cardarine is banned by WADA and can not be used in professional sport or in any tested competitions – that includes drug tested bodybuilding contests.

Cardarine Review Alongside Trenbolone

Cardarine pairs well with Trenbolone because it can counteract a lot of the negative side effects such as night sweats, reduced endurance, loss of libido, shortness of breath, increased blood pressure and a poor balance between cholesterol levels (high LDL and low HDL).

Tren severely reduces your cardiovascular potential so using Cardarine alongside a Tren cycle makes a very noticeable improvement. Cardarine improves endurance levels and helps athletes to push further, recover faster and greatly improves their cardiovascular health.

Studies have shown that GW-501516 has a positive impact on the balance between HDL and LDL cholesterol which can offset the negative side effects of Trenbolone.

In one study, Cardarine increased HDL cholesterol and decreased triglycerides, insulin, and LDL cholesterol, which may altogether decrease the risk of heart disease.

A number of studies have also shown that Cardarine helps to lower high blood pressure.

Cardarine Review – Before & After Photos

Cardarine is one of the best compounds when it comes to boosting fat loss and increasing your endurance, energy and stamina. This PPAR modulator has been proven through valid research to have many health benefits but its performance benefits are its top advantages.

When it comes to fat loss, you’ll notice a major difference as well as an increase in vascularity as Cardarine promotes the burning of fat as a source of fuel. You’ll also see dramatically reduced recovery times after working out, and even a boost in your mood.

cardarine before and after — Cardarine 12-week cycle before and after photos

Incredible endurance enhancement
Dramatically reduced recovery time
Works from the first dose
Improves your mood
Enhances fat loss
Ideal for interval/cardio training
Stackable with other SARMs
Is NOT a stimulant and doesn’t increase heart-rate
Can be stacked with any other fat burners for maximum fat-burning potential

Read our blog to see more SARMs Before and After Photos.

How Does Cardarine Work?

Cardarine GW 501516 binds to the PPAR-delta nuclear receptors which are mostly in your muscles and stimulates some of the genes which govern how your body uses energy. By doing these two things, Cardarine can:

Help you burn more body fat – by preventing fatty acid chains from being formed, and therefore stopping your body from storing fat, so your system has to use stood fat for energy
Preserve existing muscle mass – when you are in an energy deficit and your body is forced to use fat for fuel, Cardarine can also protect muscle mass from catabolism
Faster recovery – Cardarine may increase the amount of oxygen which gets to your muscles, helping you recover from training sessions

Cardarine Review for Bodybuilding

1 Fat burning

Cardarine can help you burn more body fat by encouraging your body to use stored fat for fuel, by stimulating glucose, and by activating some of the genes involves in fat burning.

2 Bulking and cutting

Cardarine can be stacked with other SARMs to encourage fat loss, boost training performance, and help you maintain muscle mass when dieting – ideal for cutting and bulking cycles.

3 Brain health

Cardarine can improve blood flow to the brain, protecting brain vessels, boosting the growth of nerve cells, and reducing problematic inflammation.

4 Training endurance

Cardarine stimulates your body’s use of glucose for fuel, which means you can probably train longer and harder. More training = more muscle gain!

5 Muscle growth

Cardarine activates the PPAR-delta which boosts muscle fibres, gives you increased energy and means you can train for longer too.

6 Heart health

Cardarine may have a protective benefit for your blood vessels, reducing oxidative damage and plaque build-up, and increasing your levels of nitric oxide.

How To Dose Cardarine

Cardarine is kind of an all-rounder, you can use it for cutting or bulking cycles. It has a half life of 16 hours, so you will need to split your daily total dose into two doses. Start with 10mg/day (5mg twice per day), ideally with one dose 2-3 hours before you train. Run Cardarine for a maximum of 12 weeks, followed by a 6 week off-cycle break.

Can You Stack Cardarine?

A Cardarine Review wouldn’t be complete without some stack suggestions, so here they are! GW can be stacked with most other compounds. It mitigates fat-gain during bulking cycles, increases fat-loss during cutting cycles, and enhances endurance and performance all-round. Here are the most popular SARMs stacks:

Body-Recomposition Stack

Cardarine GW-501516
Ligandrol LGD-4033
Andarine S-4

Cutting Stack

Testolone RAD-140
Cardarine GW-501516
Stenabolic SR-9009
Andarine S-4

Strength Stack

Testolone RAD-140
Cardarine GW-501516
Andarine S-4

Bridging Stack

Andarine S-4
Ostarine MK-2866
Cardarine GW-501516
Stenabolic SR-9009

Endurance Stack

Cardarine GW-501516
Stenabolic SR-9009

Bulking Stack (with minimum fat-gain)

Cardarine GW-501516
Ostarine MK-2866
Ligandrol LGD-4033
Testolone RAD-140

Does Cardarine Have Any Side-Effects?

Like any compound, you should be sensible about using Cardarine. This includes looking out for side effects. Cardarine won’t suppress your natural hormone levels. It is always recommended to start off with lower doses and assess response and adaptation. If there is anything we haven’t covered in this Cardarine Review, see our Guide to Cardarine for more information.

16/09/201922/09/2019

In Fat Loss, SARMsby Nicola Joyce

Andarine S4: Benefits, Dosages (Complete Guide)

Andarine (also known as S4) is a powerful selective androgen receptor modulator which can support muscle growth, mass, and density. This article will tell you everything you need to know about this increasingly favourable compound.

What Is Andarine S4?

Andarine S4 is a SARM (a selective androgen receptor modulator) sometimes also known as SARM S4. Like many SARMs, it has positive benefits on muscle mass, muscle gain and anabolism (helping you build muscle tissue and minimise muscle loss). But Andarine is stronger and more potent than many other SARMs.

Different SARMs have different levels of potency and this shows up in the results you can expect (and in what timeframe). What you need to know about Andarine is that it is pretty strong as SARMs go – so you can expect measurable results in a short time frame.

But there are some side effects to watch out for and we’ll detail those further in this article. However, Andarine is selective in which receptors it binds too, so side effects should be minimal if you are healthy and stick to recommended dosages.

Andarine works by binding to androgen receptors (in muscle tissue and bone tissue) which encourages your body to grow muscle. As a by-product of this, you’ll get stronger in the gym, you’ll be able to lift more and recover faster which will lead to yet more muscle gain.

Andarine S4 has been through human trials but no studies were published. There is some limited information which suggests that S-4 was described as the ideal SARM due to its single-day dosing, complete oral bioavailability and significant anabolic effects.

Understand The Benefits Of Andarine S4

Andarine can be used for bulking, cutting, body recomposition, strength gains, or competition prep but please remember you can not use Andarine – or any SARM – if you compete in drug-tested sport, including tested bodybuilding competitions because SARMs are banned by WADA.

Dense muscle tissue – Andarine is renowned for giving that hard, dry look to muscles (which is why bodybuilder like it). Ideal if you want a full, pumped look
Fat loss – Andarine seems to help with fat loss, possibly because it increases the metabolism of body fat and suppresses HSL (hormone-sensitive lipase)
Strength gains – Andarine helps you build strength, and you may notice significant strength gains within a few weeks
Dry gains – you shouldn’t experience water retention with SARM S4, meaning your muscle gains will look dry, not watery
High bioavailability – meaning Andarine is absorbed into your system quickly, so it gets to work rapidly, even at low doses

You can see why S-4 is popular with bodybuilders, powerlifters, and other strength and power athletes. Just be careful with tested competition – like we’ve said, Andarine is banned (as are all SARMs) by WADA.

Are There Any Side Effects Of Andarine S4?

You should stay open to the possibility of side effects with any compound or medicine. Andarine is no different. Remember, SARMs were originally developed as potential medical solutions to physical issues, and most drugs have some potential side effects.

So what are the side effects of Andarine, and how can you minimise the chance of them happening? There are two key side effects to be aware of:

Night vision disturbance – some people report a kind of yellow tinge to their vision at night (probably because SARM S4 binds to receptors in the eyes). This shouldn’t be a problem – unless you work shifts, or need to drive or operate any kind of machinery at night. Most of these reports come from people taking high doses of Andarine.
Testosterone suppression – S4 does impact your natural test levels, and you will need to do a PCT (post cycle therapy) after using Andarine. Another way to keep this risk to a minimum is to run short cycles of 8 weeks maximum.

How To Use Andarine, Best Dosages

The best way to minimise the risks of any side effects is to get informed about how to use Andarine. This includes how much (dosages), how often (should you split the dose), and for how long (cycle length).

Andarine is a strong SARM, which means you can see good results even at low doses, so there is no need to take high doses – in fact, this just opens you up to more risk of side effects, for no need.

Start with 20mg-25mg Andarine a day.
Split your dose (whatever dose you take) into 2-3 doses per day. Take a dose in the morning, and one with your pre-training meal. If you are taking 1/3 dose, do this 4 hours after your previous dose.
After 2 weeks, assess your progress and results
If your progress has slowed down or stopped, increase the dose by 5mg per week for the rest of your cycle.
Do not keep increasing the dose all the while you are getting results – only increase it if your results stop.
Never go higher than 50mg/day (in fact, 35mg/day is a high dose).
Never take Andarine S4 for longer than 8 weeks (6-8 weeks is the least risky).

Andarine vs Other Popular SARMs

S4 is sometimes stacked with Ostarine (for cutting). Ostarine can be beneficial for building muscle mass and body recomposition. Andarine can also be stacked with Cardarine (for strength training), or with Ligandrol (for bulking). Remember, Andarine is already a strong SARM so there is no real need to stack.

Andarine S4 is a powerful SARM which is a kind of all-rounder, helping build muscle mass, burn body fat, and boost strength. But remember it is banned by WADA and can not be used for any tested sport or competition.

MK-677 Before and After Photos: Impressive Results

30/08/201929/09/2019

In Fat Loss, SARMsby Nicola Joyce

MK-677 Before and After Photos

As you might know, MK-677 is one of the most interesting compounds currently being used by athletes and bodybuilders, so we’ve pulled together a variety of MK-677 before and after photos to see just what’s realistically possible. Ibutamoren is a very potent but slow-acting compound that takes a while to kick in but when it does, results are impressive.

Perhaps you’ve read that MK-677 is a SARM, or seen it referred to as Ibutamoren or Nutrobal and you’re probably wondering exactly what this wonder-compound is (and how it can help you with your strength and physique goals). The first thing you need to know is that Ibutamoren is not a SARM. Let’s find out more about this muscle-building, fat-stripping compound so you can make an informed decision about your cutting stack.

What Exactly Is Ibutamoren MK-677?

Ibutamoren is often marketed as a SARM (selective androgen receptor modulator) but it’s actually not a SARM at all. It’s a chemical compound which can boost your body’s natural hormone levels so you can speed up muscle growth for bigger, denser muscles, more mass, greater strength, and an easier time when you next try to lean down.

MK-677 is a growth hormone secretagogue; a substance that causes growth hormone and IGF-1 to be secreted in your body. It does this by imitating ghrelin, binding to ghrelin receptors in the brain, and encouraging your natural production of GH and IGF-1. Using Ibutamoren boosts your body’s own levels of these anabolic hormones without disturbing other hormones like testosterone or cortisol. This means it is safe for long-term use and doesn’t require any form of PCT.

Ibutamoren & Bodybuilding

As mentioned, Ibutamoren boosts your body’s levels of the anabolic hormones GH (growth hormone) and IGF-1. This means it has impressive anabolic properties but without the side effects associated with actual anabolic steroids.

Ibutamoren is taken orally and can help you increase muscle mass, boost muscle size and improve your strength in training too (which will obviously also lead to better gains). It can also help you lose more body fat during a cutting diet or a body recomposition phase.

This 1998 double-blind, randomised human study shows impressive results in a group of males given Ibutamoren MK-677 – they showed increased lean mass, GH secretion, and even energy expenditure in just two months. That same study showed that serum IGF-I increased by approximately 40% with Ibutamoren MK-677 treatment.

Our MK-677 before and after photos will follow soon, keep reading…

8 Benefits of MK-677

#1 Muscle retention

Ibutamoren has been shown to reverse protein loss and associated muscle wasting – good news for bodybuilders who want to diet to lose fat but hate the idea of sacrificing hard-earned muscle mass. Muscle gain made with HGH is longer-lasting, so any gains you make on Ibutamoren are likely to last longer, too.

#2 Muscle gain

Ibutamoren MK-677 doesn’t just help you hang on to muscle mass in the face of a possibly catabolic environment. It can also boost the growth of new muscle cells. It does this by stimulating secretion of GH and IGF-1 which increase protein synthesis. That means hefty gains if you’re already eating and training right.

#3 Bone density

All that extra growth hormone will mean better bone density in the short term and the long term, which is good news for your gains now, and for your health, once you get older. Look better and stay more active in later life? Yes, please.

#4 Sleep and recovery

Ibutamoren may improve the amount of REM sleep you get (and the quality of your sleep), which means better recovery between training and more time in that muscle-gaining anabolic state. Better sleep also means more energy for training the next day, plus less hunger and fewer cravings.

#5 Nootropics

Ibutamoren is also popular with the nootropic crowd because it is thought to have brain benefits. This means better wellbeing and mood, with more motivation and focus on training and cardio.

#6 Fat loss

Using Ibutamoren may encourage your body to use stored fat for energy, and remember that it protects muscle at the same time. This means true lean gains: fat loss with muscle gain for that full, pumped, shredded look. Our MK-677 before and after photos are specifically showing the fat-loss results that people have experienced.

#7 Anti-ageing and longevity

Ibutamoren may promote longevity by increasing growth hormone and IGF-1. IGF-1 is known to have beneficial effects on ageing and longevity, however, our natural production of growth hormone declines from mid-puberty throughout life. In a study with 65 healthy adults, daily administration of MK-677 increased GH and IGF-1 levels without negative side-effects. In another study with 24 obese males, MK-677 rejuvenated the growth hormone profile.

#8 Skin tightening

Ibutamoren is known for its positive effects on the quality of hair, skin and nails. Not only does it increase fat oxidation but you’ll also notice that it will also tighten the loose skin and improve the skin quality. This is also one of the reasons why it is often used for anti-ageing, as mentioned above. In fact, many women use MK-677 to combat wrinkles and cellulite!

MK-677 Before and After Photos

These MK-677 before and after photos show cycles of different lengths. It is worth noting that this compound shows greater results if used long-term and progress will also depend on different individual factors. Your diet, training, recovery and whether you decide to stack MK-677 will greatly affect your potential. Anecdotally, people are finding very noticeable and significant effects so it’s safe to say that MK-677 is worth its weight in gold.

mk 677 before and after 02 — MK-677 Before and After – 8 Week Cycle

mk 677 before and after 03 — MK-677 Before and After – 12 Week Cycle

mk 677 before and after 01 — MK-677 Before and After – 16 Week Cycle

If you looking for more than just MK-677 before and after photos, check out our SARMs Before and After Photos to see what else is available.

MK-677 Dosage & Stacking

Ibutamoren MK-677 can be taken by itself or as part of a stack with other compounds. It has a long half-life of 24 hours which means you can take your daily dose in one go – but it does spike growth hormone, so you might like to split your dose to avoid tiredness after the GH spike.

Most users will tend to use 20-25mg per day although MK-677 is still very effective at doses as low as 10mg, which can be useful for people who feel tired or hungry at higher doses. Start at 10mg for the first week to assess how you feel if it’s your first time using the compound.

The efficacy of MK-677 increases and improves with longer-term use, so the recommended cycle length is 3-6 months for optimum results. Some people like to stay on MK-677 year-round. Our MK-677 before and after photos show different cycle lengths but keep in mind that everyone is different and your training, diet, recovery and stacking will hugely affect results.

Recommended dosages:

Building muscle: 25mg per day
Fat loss: 20mg per day
Heal an injury: 10-20mg per day
Anti-ageing: 10-20mg per day

If you are new to Ibutamoren, start with 10mg for one week to assess your response before increasing dosages, if necessary.

Stacking MK-677 with SARMs

Ibutamoren has very minor side-effects, but it should still not be taken lightly. You still have to be careful when choosing your dose, especially if you plan on stacking it with other SARMs. And then you also have to figure out how to stack them.

But if you do choose the right dose and stack your SARMs properly, then you can expect amazing results in a short amount of time. Ibutamoren can actually enhance the effects of the SARMs that you’re currently taking.

MK-677 is often stacked with Cardarine, Ligandrol and Testolone but it is an exceptionally versatile compound and can be stacked with anything else. See our Stacks for recommendations based on your goals.

Our Best-Selling MK-677

You need to be sure the MK-677 you use is good quality, pure and well dosed. Be wary of any product which isn’t clearly labelled or can’t tell you how much of the active ingredient you are getting (we call this “micro-dosing” in the industry, and it’s bad news!).

Check out Mutagenic Labz MK-677 for a quality, reliable source of Ibutamoren Mesylate. Each capsule gives you 10mg of MK-677 so you can start small and build up your dose, or stay on a low dose for a longer period of time.

Cardarine GW-501516: A Complete Guide to GW501516

05/07/201912/05/2022

In Fat Loss, SARMs, Supplementsby Nicola Joyce

Cardarine GW-501516: A Helpful Guide 2019

In this article, we’ll cover everything you need to know about the PPAR-delta activator Cardarine (GW-501516), how long it takes to work, the ideal cycle length, safety and vital information you need before you consider adding it to your supplement regime.

A lot of the compounds we write about at PumpingIron.com are SARMs (selective androgen receptor modulators). This article is about something a little different, although often classed into the same category. GW501516 can help burn fat, boost metabolism, increase training endurance and protect muscle tissue but it isn’t actually a SARM. It’s a non-hormonal PPAR-delta activator which doesn’t work on the androgen capacitors at all.

If you’re curious about Cardarine, here’s everything you need to know and if we haven’t covered something, simply e-mail us and we’ll be happy to answer your questions!

Is Cardarine (GW-501516) a SARM?

As we said, Cardarine isn’t actually a SARM (anyone who tells you it is doesn’t know what they’re talking about). A SARM activates androgen receptors in muscles and other tissue. Cardarine is a PPAR-delta activator but it can produce results similar to those of SARMs.

Background Information

The best way to understand what to expect from a compound is to look at why it was developed (and what was discovered by researchers). GW501516 was originally developed by a drug company in the 1990s as a way to prevent tumours (especially on the colon and prostate). But there were some surprising discoveries.

During their studies into increased endurance and fat burning, the researchers began to understand more about the PPAR-delta pathway. They realised that activation of this pathway had an astounding impact on muscle growth, endurance and energy whilst decreasing blood lipids and subcutaneous fat. And – you guessed it – the compound GW-501516 can bind to this PPAR-delta pathway.

It turned out Cardarine could help reduce body fat, boost metabolic rate, improve the strength of blood vessels. This has a positive impact on cardiovascular health, increases muscle growth rate and even reduces recovery time. We’ll go into these factors in greater depth later in this article.

One thing we need to make clear: Cardarine is not currently sold for human consumption. It is classed as a ‘research compound’, sold for research purposes only.

How Long Does Cardarine Take to Work?

It’s important to understand how the Cardarine works in the body. Like we’ve already said, it binds to PPAR-delta in muscle cells and it stimulates certain genes which facilitate the body’s use of energy. Once you know that, you can see how it can boost your metabolic rate, improve physical performance and even help burn more fat (whilst increasing and protecting muscle mass).

You’ll notice the effects almost instantly; timing one of your dosages about thirty minutes before a high-intensity training session is an ideal protocol. The difference in energy, endurance and stamina will be noticeable almost immediately.

Burn Fat & Recover Faster with GW-501516

How exactly does Cardarine burn body fat? It’s not as simple as just torching fat right off your body. It starts with preventing the formation of fatty acids chains which, in turn, stops your body actually storing fat. This means your body needs to tap into your subcutaneous fat stores for energy – just like when you diet. But there’s one big difference to when you burn body fat by dieting. GW-501516 has those sought-after anti-catabolic properties, which means you get leaner without losing valuable muscle tissue.

What about boosting recovery between training sessions? It seems Cardarine can help your muscle fibres (specifically the slow-twitch fibres) use oxygen more efficiently, and this can help improve rates of recovery between training. It can also mean better endurance during training sessions. Good news if you train for hypertrophy, with a lower-load and higher-rep style of training.

Cardarine & Bodybuilding

You can already guess that this is an attractive compound for bodybuilders with its potential for muscle gain, training recovery and fat burning. (Side note: it’s also getting a lot of interest with the nootropics crowd.)

Cardarine could be used by itself or with other compounds as a cycle; you can stack it with prohormones, SARMs or other fat-burners. You can also use it to bridge between cycles or throughout a PCT (post cycle therapy) phase. Either way, it should be cycled for best results. Plan your cycle length for 8-12 weeks before having a 4-8 week break.

GW501516 has a half-life of 12-24 hours so you can decide whether to split your dose or to take it once per day. A dosage of 10mg-20mg per day is recommended.

Stacking Cardarine with Other Compounds

Cardarine can be used as a standalone supplement but is often stacked with other compounds. Most commonly, it has great synergistic effects with MK-677, RAD-140, Ostarine, LGD-3303 and Andarine.

It can also be used to combat negative side-effects of some anabolics (such as Trenbolone) and address potential lipid health issues. Cardarine is beneficial during PCT because it can lessen your chances of a fat-regain or rebound after running a steroid or prohormone cycle.

7 Things You Need To Know About Cardarine

#1 Fat Burner

It boosts your body’s fat-burning capacity by stimulating glucose and activating the ABCA1 and CPT1 fat-burning genes. Interestingly, there was a human study done on Cardarine’s potential for receding fatty acids, VLDL proteins and triglycerides (human studies on Cardarine are pretty rare, so it’s worth a look at this one).

#2 Training Endurance

It can stimulate the body’s glucose uptake, encouraging your body to use glucose as its primary fuel source. This means you get more energised for training and can train harder for longer. Since Cardarine can activate PPAR-delta pathways, it can also improve strength endurance. This 2015 study (on mice) suggests Cardarine can increase the specific muscle fibres associated with peak training performance.

#3 Lean Gains

It is a popular choice for stacking with SARMs and other compounds to protect lean muscle tissue whilst dieting to get shredded. As we’ve said, it can help burn body fat without the problem of losing muscle mass or looking over-dieted and scrawny.

#4 Brain Health

It can have a positive effect on blood vessels (see #5) and this means protection for your brain blood vessels (plus more blood to the brain). You might also like to know PPAR activators are thought to boost nerve cell development of nerve cells.

#5 Cardiovascular Health

It can prevent oxidative damage to blood vessels, helping reduce build-up in the arteries and (most exciting for bodybuilders) increasing your nitric oxide (NO) levels. This could mean Cardarine may reduce inflammation and associated tissue damage – a key factor in recovery and muscle growth during hypertrophy.

#6 Liver & Kidney Health

MCP-1 activity is a key factor in kidney disease and Cardarine can reduce this activity. Additionally, Cardarine acts directly on your liver (a powerhouse for storing fats for fuel in the body), using PPAR-delta activation to use fatty acids for energy. Cardarine could even reduce the body’s production of IL-6 and thereby prohibit insulin resistance.

#7 Muscle fibres

Activating PPAR-delta also means Cardarine can encourage better muscle fibre development. This means increased training endurance and the potential for greater muscle growth.

Choosing & Using Cardarine GW-501516

The bottom line is that Cardarine GW501516 is not currently legal for human consumption so it is sold for research purposes. Not for training, cutting, bulking, or bodybuilding.

You also need to bear in mind that Cardarine is banned for any tested bodybuilding competitions (yes, even trace amounts found accidentally in another product). At the moment, almost all the (limited) research on Cardarine GW501516 is on animals.

Don’t risk wasting your money on cheap, fake dupes!

One of the best selling products Mutagenic Labz Amalgamation combines a blend of GW-501516 and SR-9009, a very effective fat-loss combo. If you’re not keen on Cardarine just yet, Check out Mutagenic Labz Assimilation – our safe, legal and insanely effective GDA (Glucose Disposal Agent) to help you get leaner and build more muscle faster.

Disclaimer: By publishing this post we are not recommending using GW501516. It’s our duty to inform and educate you on all compounds. All of the information we have given here can be corroborated by published scientific reviews and literature. We recommend Mutagenic Labz Assimilation.

13/02/201926/03/2021

In Fat Loss, SARMsby Nicola Joyce

SARMs Results: Complete Rundown (2021)

When it comes to SARMs results, there’s a huge variety of compounds to choose from and all have different strengths. Although SARMs are highly versatile, they do produce slightly different results, have different potencies and can be utilised in different phases for different goals.

So, what are the effects and benefits of different SARMs compounds?

SARMs – selective androgen receptor modulators – are the most exciting modern development in supplements, sweeping aside the need to even think about risking your health on illegal substances like anabolic steroids or prohormones. SARMs can give you some astounding results with little to no side effects, no hormonal suppression, and no known health risks.

But what exactly can you expect from taking SARMs? It’s all very well reading about the benefits and looking at other people’s before and after photos. Wouldn’t it be useful to know what to expect from the most popular SARMs compounds, so you can select the precise ones to get the physique you want?

Most SARMs have some effect on rates of muscle gain, the appearance of muscle, as well as on strength, training performance, and rate of fat loss. But they are all slightly different. How are the various SARMs different, and what can you expect when you take them alongside a good diet and regular training?

Let’s find out.

SARMs Results

Results From ACP-105 SARM

ACP-105 is one of the newer SARMs and has been researched in relation to treating bone and tissue conditions including osteoporosis and muscle wasting conditions. Although ACP-105 is not one of the stronger SARMs, it has powerful anabolic effects and is comparable in some ways to synthetic testosterone. However, it seems to have minimal suppressive effects on the body’s natural hormone levels which is great news. It is what’s known as a partial agonist.

ACP-105 results include strength gains, muscular endurance, and better muscle mass gains. It is known to be one of the weaker SARMs (for want of a better word), so don’t expect insane results – just visible, pleasing ones!

SARMs results to expect from ACP-105:

Muscle and strength gains
Improves the rate of fat loss
Better muscle recovery from training
Increased rate of muscle growth
Improved blood circulation
Non-toxic to the liver

Cardarine (GW-510516) PPAR Modulator

Cardarine is not actually a SARM – it is a PPAR-delta activator. This means it doesn’t directly influence the androgen receptors. Cardarine was initially researched for its fat-burning potential and further developed to potentially treat health issues around the heart and blood vessels. It is known to have a range of benefits for athletic performance and bodybuilding, including reduction of inflammation and increased fat-burning potential.

Helps maintain good blood flow to the brain
PPAR-delta activation increases fat burn and energy use
May even reverse symptoms of metabolic syndrome including liver fat and triglycerides
Lowers cholesterol
Increases nitric oxide to minimise oxidative damage to blood vessel
Lowers risk of heart disease
Suppresses inflammation (another benefit of activating the PPAR-delta pathway)
Encourages the liver to use fatty acids (to glucose) as energy which can reduce blood sugar
Better development of muscle fibres for strength, endurance, mass

Results From Ostarine (MK-2866) SARM

Ostarine has been researched for its potential to reverse the effects of catabolism in muscle-wasting diseases and the ageing population. It is still in the clinical trial stage, making it one of the SARMs more likely to be approved for clinical use. Ostarine is favoured by bodybuilders for its effects on muscle gain and strength gain with minimal risk of side effects.

SARMs results to expect from MK-2866:

Increases muscle mass and strength
Gives a dry, lean muscle gain appearance
Supports better fat loss without muscle loss
No water retention
Better pumps during training
Can reverse muscle loss (potentially when dieting in a calorie deficit)
No known impact on hormone levels
Beneficial for bone strength and bone density
Can lower cholesterol and blood glucose
May activate muscle satellite cells to help regenerate muscle tissue and connective tissue
No need for PCT or liver support supplements

Results From Ibutamoren (MK-677) Growth Hormone Secretagogue

Ibutamoren isn’t a SARM but a growth hormone secretagogue that is known to stimulate your natural production of growth hormone to increase GH levels. By increasing the body’s secretion of GH, it also increases IGF-1 (insulin-like growth factor) both of which are key anabolic hormones. Ibutamoren binds to a part of the brain that plays a part in appetite.

Increases growth hormone secretion
Increases IGF-1
Improves muscle mass gain
Can reduce muscle loss during dieting phases
Boosts ability to lose body fat
Bone strength and bone density
Can improve sleep
Some nootropic effects for better cognition and mood
May even help with hangovers!

Results From LGD-3303 SARM

LGD-3303 is one of the newer SARMs – don’t confuse it with LGD-4033 (Ligandrol). 3303 and 4033 do have similarities but you need to know the difference. Anecdotally, we hear that LGD-3303 is the stronger SARM and perhaps better for fat loss on a cut. LGD-3303 was developed as a potential for treating osteoporosis, and may be beneficial for treating loss of muscle tissue in older people.

SARMs results to expect from LGD-3303:

Great bioavailability
Minimal water retention
Good choice for dieting phase (less water retention)
No negative effect on androgenic organs
Increases bone density and bone mass
Muscular fullness and hardness
Can help offset catabolism to retain muscle mass
Increased endurance for training sessions

Results From Ligandrol (LGD-4033) SARM

LGD-4033 is often called the most potent of the SARM compounds. It was developed to improve patients’ recovery from fractures, because of its effect on tissue regeneration and strength.

SARMs results to expect from LGD-4033:

Muscle mass gains (good choice for a bulk)
Fat loss (although may temporarily be masked by some water retention)
Strength increases
Bone density and bone strength
Positive effects on catabolism including cachexia
Can help retain muscle whilst dieting
Increased sense of wellbeing and libido

Results From Stenabolic (SR-9009) REV-ERB agonist

SR9009 is not a SARM, it is a REV-ERB agonist. It mediates optimal metabolic function being described often as an exercise mimetic, or something which can provide similar effects as can be expected from exercise.

Stenabolic was developed for its effects on the circadian rhythm – it enhances REV-ERB (the proteins which stabilise our internal body clock). It has been shown to impact a number of health factors including anxiety, endurance, cholesterol, and inflammation. SR9009 has the ability to affect weight loss without dieting, according to a 7-day study on mice.

Can impact the genes under circadian control
Potential to boost fat burn and increase mitochondria activity
“Turns off” the genes which encourage fat storage
Potent metabolism booster and fat burner
Enhances endurance and stamina
Enhance REV-ERB activity
Reduces fat and cholesterol
Reduces inflammation
Improves heart function
Promotes wakefulness
Combats anxiety
Non-stimulant and non-hormonal
Reduces levels of triglycerides and total cholesterol in the blood
Muscular endurance for improved training performance
Supports better mood and energy, reduces anxiety

Results From Testolone (RAD-140) SARM

Testolone mimics testosterone but avoids the side effects of traditional testosterone supplements. It is being used in research for increasing muscle mass and protecting brain cells from degeneration.

SARMs results to expect from RAD-140:

More anabolic than testosterone
Anabolic to androgenic ratio of 90:1
A great addition to a prohormone cycle
Best for bulking cycles
Improves libido and sexual performance
Best SARM for muscle growth and size
Reduces fat and increases muscle mass
Ideal to enhance body composition
Rapid muscle recovery
A safer alternative to anabolic steroids
No androgenic side effects such as male pattern baldness
Excellent stacking potential with other SARMs and prohormones
PCT required

Results From Andarine (S-4) SARM

Like many SARMs, Andarine was developed for its potential to treat muscle wasting conditions and osteoporosis. It has been shown to increase strength, muscle mass, and bone density, muscle mass.

SARMs results to expect from S-4:

Potent hardening agent for exceptional body re-composition
One of the most researched SARMs in the industry
Highly anabolic
Preserves and improves lean body mass during diet phases
Increases oxidation of fatty tissue
Non-liver-toxic
No aromatization
The ultimate SARM with an exceptional potency

Results From S-23 SARM

S23 is a new SARM, which has been found to trigger an anabolic response for a positive effect on muscle and bone and muscle tissue. A safer alternative to anabolic steroids, S-23 is extremely effective for burning stubborn body fat. Considered by many as a powerful version of S-4 (Andarine), S-23 is one of the best performance-enhancing drugs to harden muscle for a dry, grainy look.

SARMs results to expect from S-23:

Increases both skeletal and muscle mass
Promotes long-lasting muscle mass and endurance gains
Ideal for muscle hardening
Completely sets off catabolism in a calorie deficit
Increases bone strength and reduces fat mass
Improves libido in men and women
Helps users to retain gains long after a cycle
No bloating or fluid retention

Results From YK-11 SARM

YK11 is being talked about as a myostatin inhibitor which can boost physical and mental aspects of bodybuilding. It offers a lot of benefits without any apparent side effects.

SARMs results to expect from YK-11:

Highly anabolic compound with fewer side effects than a steroid
Enhances muscle mass via myostatin inhibition
Increases muscle building with fewer side effects than prohormones
No estrogenic side effects
No hepatoxicity so safe to stack with another SARM or prohormone
Faster muscle growth than any natural test booster
Much improved recovery

Before you use any SARM, be sure to buy a reliable product from a trustworthy manufacturer and distributor. Always start with the lowest possible dose and asses your progress as you go along. Side effects have mostly been reported at high doses (higher than the recommended doses), or long cycles. Be smart and sensible, and you’ll reap the rewards of these incredible compounds.