Best SARMs Stack for Cutting

Best SARMs Stack for Cutting (Updated 2022)

SARMs are getting increasingly more popular amongst bodybuilders, competitors and athletes, so one of the most common questions we get is to recommend the best SARMs stack for cutting. It’s not surprising when you consider that these compounds can help build muscle, give a denser, harder look to muscle and help burn body fat beyond our natural potential.

That’s the holy grail – adding mass and not losing it again when you diet! Not to mention, to speed up the process of losing body fat and revealing those chiselled abs!

Which are the best SARMs for fat loss? Here’s our take on it…

What Are SARMs & How Do They Work For Dieting?

SARMs are “selective androgen receptor modulators”, compounds which selectively bind to androgen receptors in the body’s tissues to help manipulate our natural hormone levels. Androgens are hormones which signal the body to make changes – like the way testosterone signals the body to grow.

By binding to some of the receptors which receive these hormonal messages, SARMs can specifically boost some of those signals. The key here is in the “selective” part of the name. SARMs don’t bind to every receptor (unlike anabolic hormones, which do). They only bind to receptors in bone tissue and muscle tissue. This selective nature means you get more specific in what you want the SARM to do, and you can avoid a lot of the side effects associated with steroids.

Most SARMs were initially developed as a possible way to create certain medical conditions, specifically those related to loss of bone density, muscle mass, and strength. They caught the eye of researchers because they were able to bind only to the affected tissues, and not to anything else like internal organs.

SARMs can be taken as orals which makes them easier and more user-friendly than anabolics.

But what about using SARMs for fat loss? In this article, we will look at how to use SARMs for cutting (fat loss dieting) whether you want to do that for your health, your appearance, or as a bodybuilder.

The Best SARMs for Cutting

In order to put together the best SARMs stack for cutting, we’ll take a look at the different SARMs that are best for fat loss, and the reason why they make a good choice for your dieting phase.

Each of the different compounds below has superb fat-shedding qualities and these are often interchanged depending on the preferences of the individual user. In short, the best SARMs stack for cutting is the one that works for you! See which compounds fit your preferences and do your research – that is always the best way.

Andarine S4

Andarine, or S4, is a strong and potent SARM which is thought to increase fat oxidation and reduce lipoprotein lipase which is linked to fat accumulation in the body. Initially developed to combat conditions such as osteoporosis and muscle wastage, S-4 is one of the most researched SARMs which is always a positive aspect.

Andarine also helps increase muscle mass and strength. Even low doses of Andarine can help you maintain all your gains when you go into a calorie deficit to get lean. All in all, a good choice for cutting or body recomposition.

Best dose: start at 25mg/day split into 2-3 doses (4-6 hours apart), never go higher than 50mg/day and keep cycles to an 8-12 week maximum.

Ostarine

Ostarine MK 2866 really helps boost muscle gain because it increases the body’s levels of nitrogen and protein. This makes it a good choice for protecting muscle mass when you diet, avoiding that stringy, over-dieted look.

LGD-3303 (Not LGD-4033!)

A quick update here: LGD-3303 has now been patented by pharmaceutical company Ligand Pharmaceuticals Incorporated and is no longer available on the market.

LGD-3303 is a potent and highly selective androgen receptor full agonist in skeletal muscle, a classic target tissue for androgen action. By comparison, in the prostate and sebaceous glands, the compound is a weak partial agonist. The sparing of these non-target tissues by effective, pharmacologic doses of LGD-3303 provides a novel and potentially safer treatment for osteoporosis.

Source: Ligand Pharmaceuticals Incorporated

Here’s where our recommendation on the best SARMs stack for cutting is different from any other you may have seen online. Most will recommend Ligandrol but we beg to differ. LGD-3303 is the leaner, dryer, fuller and more vascular successor of Ligandrol (LGD 4033). For that reason, it undoubtedly takes the throne.

Cardarine

Cardarine GW 501516 isn’t actually a SARM but a PPAR gamma receptor agonist that binds to PPARδ receptors instead of androgen receptors like a SARM normally would.

Cardarine supports healthy cholesterol levels and increases your basal metabolic rate, which helps your body to burn more energy (aka fat) even when at rest. You might also feel an energy boost, which definitely helps when you are dieting in a calorie deficit! Cardarine is a compound we stack with pretty much anything; this one’s a winner all-round… even when bulking to mitigate fat gain.

Stenabolic

Stenabolic SR 9009 is another on this list which isn’t actually a SARM (it’s a REV-ERB agonist) but it deserves a place on this list. As a REV-ERBα agonist, it can help manipulate certain functions relating to the metabolism, so you feel more energised, burn more stored fat, and get a boost to your metabolic rate even at rest. Stenabolic is also a compound we love to stack with pretty much anything.

MK-677

MK-677 is a growth hormone secretagogue and stacks well with virtually anything. It is a very versatile compound that can be used for both bulking or cutting, depending on the accompanying diet and training plan (increased calories will support bulking and reduced calorie intake supports fat loss).

Glucose Disposal Agents

Although Glucose Disposal Agents aren’t SARMs, they deserve a mention. Nutrient partitioning often gets forgotten about but is so effective when it comes to body composition. A glucose disposal agent decreases the amount of insulin secreted by the body when eating a high-carbohydrate meal and shuttles glucose into muscle cells instead of storing them in fat cells. This results in reduced fat gain and a potential increase in lean muscle gain.

The Best SARMs Stack for Cutting

As we’ve already pointed out, you can stack different SARMs to assist you during a cut and there are different ways to mix and match the compounds that work best for the individual.

One of the best SARMs stack for cutting we’ve researched is for the more advanced and experienced:

  • Andarine S-4 – 50mg per day, 25mg in the a.m. and 25mg 4-6 hours later
  • Ostarine MK-2866 – 20mg per day, dosed once a day in the a.m.
  • GW/SR (SR-9009/Cardarine Blend) – 1 capsule in the a.m, 1 capsule in the p.m.
  • MK-677 – 20mg per day, dosed once per day (can be reduced to 10mg if appetite increase is unmanageable).

5 Keys To Getting Shredded

Remember that there are several aspects to getting that lean, shredded look. Sure, you need to reduce your body fat. But you also want to increase muscle mass, and – crucially – retain as much muscle as possible even as you diet to lose fat. It’s a difficult task, but SARMs can make it much easier.

1 A calorie deficit

You need to be in a calorie deficit to lose body fat, it doesn’t matter what kind of diet you follow – a calorie deficit is crucial. This means making sure your total “calories out” are higher than your “calories in”

2 Sufficient protein intake

Eating enough protein will help you build muscle, maintain muscle, and it will help keep you feeling fuller (protein has the highest Thermic Effect Of Food of any macronutrient) which will help diet compliance

3 Training frequency

We now know that training frequency is the most important factor in muscle gain and muscle retention, ideally train each major muscle group every 72 hours

4 Load and volume

Within that training, you need to put enough load (weight) and volume (weight x sets x reps) through the muscles

5 Appetite and energy management

Get control of your appetite, eating habits, and your energy output to increase your success with getting super-lean and shredded!

What’s the Best PCT for SARMs?

Although PCT is a very subjective matter, it’s often recommended to run a PCT such as Pro PCT (6-OXO).

Pumping Iron Pro PCT (6-OXO) is an advanced SARMs and prohormone PCT that contains 6-OXO, a potent aromatase inhibitor which should only be used by experienced users of SARMs and prohormones. This supplement is intended for male athletes only and shouldn’t be used by women. PRO PCT can be used to prevent estrogen related side effects on-cycle as well as a powerful recovery agent for post cycle therapy (PCT)

  • Strongest aromatase inhibitor on the market
  • Increases lean muscle mass
  • Reduces conversion of testosterone to estradiol
  • Supports muscle retention
  • Increases testosterone:estrogen ratio
  • Suitable for vegans (HMPC Veg Cap)

 

sarms cycle guide dosages blog

Best SARMs Cycle Guide and Dosages (Updated 2022)

This SARMs Cycle Guide is your go-to reference for the safest and most effective research methods when it comes to selective androgen receptor modulators. If you’re unsure about the many different compounds, their half-life and recommended dosages, then you’re in the right place.

If you’ve made the decision to run a SARMs cycle to help you increase muscle mass, gain more strength and lose body fat without sacrificing muscle, then you need to know how to do it. This article will run you through exactly how to use the most popular SARMs, including their recommended dosages.

What Are SARMs?

SARMs are Selective Androgen Receptor Modulators, chemicals which work selectively on the body’s androgen receptors to help you gain muscle and strength in a targeted way, with limited side effects.

Why Use SARMs?

SARMs are thought to have similar effects to anabolic steroids and prohormones but without the risks and side effects. SARMs are non-toxic and will not impact your body’s test levels, so there is no need for PCT (post cycle therapy) and no risk of hormone-associated side effects like gynecomastia. SARMs are known to help you gain muscle mass, build strength, and lose body fat whilst retaining muscle. If you want that big, lean look with full dense muscles, SARMs can probably help you get there.

The last decade has witnessed unprecedented discovery effort to develop selective androgen receptor modulators (SARMs) that improve physical function and bone health without adversely affecting the prostate and cardiovascular outcomes. [R]

How To Take SARMs

SARMs are widely available and not associated with side effects unless you exceed the recommended dosage. That’s why you should read up on how to take SARMs so you get maximum benefits without any risks. It’s really pretty simple to achieve your goals as long as you stay within the guidelines and buy from a trusted supplier.

SARMs are available as a powder (provided in a capsule or tablet) or suspended in a liquid. All SARMs are a raw powder isolate in their original form; it is a misconception that liquid SARMs are more effective – this is simply not the case. Ultimately, whether you do your research with capsules, tablets or liquids, will come down to personal preference.

Popular SARMs Cycles & Dosages

Each SARMs cycle is different, with various types of delivery methods, as well as varying concentrations and strengths. That said, every SARMs user sticks to a dosage range. In general, most compound dosages range from 5mg to 30mg per dose. Be aware that some SARMs have more powerful effects, even at lower doses. So always start low to assess your response and increase (in 5mg) as necessary.

Ostarine MK-2866

Ostarine is one of the entry-level SARMs; it’s relatively mild and widely renowned for its overall ‘sense of wellbeing’ effects. It’s a superb healing, recovery and joint-repair compound, making it a favourite amongst athletes. MK-2866 is widely available and very popular, either as a standalone product or stacked with other SARMs.

Ostarine is known for helping you hang on to muscle mass when you are dieting to lose fat. Usually, in a calorie deficit, you would lose fat but you would also lose some lean mass (muscle). Ostarine helps to prevent catabolism so you get leaner but preserve your hard-earned muscle mass.

Ostarine is mildly suppressive on your body’s test production (suppression levels are greater if you run your SARMs cycle for longer, or use higher doses). For this reason, many people choose to use PCT after Ostarine. For short cycles of 4-8 weeks, most people will not require PCT to recover.

  • Common dosage: 10mg-25mg per day
  • Half-life: 24 hours – full dosage can be taken once per day
  • Recommended cycle length: 8-12 weeks
  • PCT? For cycles 4-8 weeks, no PCT required. For higher-dosage cycles or longer than 8 weeks, PCT is recommended

Lingadrol LGD-4033

Lingadrol is much stronger than Ostarine but has similar effects – fat loss, muscle retention and muscle gain. It can suppress natural testosterone and the HPG axis (the hypothalamus, pituitary, and gonadal glands), so pay attention to your post-cycle therapy and recovery. Use a SERM (Selective Estrogen Receptor Modulator) between cycles of Lingadrol to protect your body’s hormones.

  • Common dosage: 4-10mg per day
  • Half-life: 30 hours – full dosage can be taken once per day and LGD will build up in the system over the course of your cycle
  • Recommended cycle length: 8-12 weeks
  • PCT cycle? Yes, a full PCT including a SERM is recommended after Lingadrol

Testolone RAD-140

Testolone is one of the newer SARMs, one of the more potent compounds in the range. It is known for its ability to help you build dense muscle mass. This is a highly anabolic SARM so only use low doses. It does inhibit natural test production, so a PCT is vital. Best used during a bulk, ideally a 12-week cycle length.

  • Common dosage: 10mg-20mg per day
  • Half-life: 16-20 hours – full dosage can be taken once per day
  • Recommended cycle length: 8-12 weeks
  • PCT cycle? Yes, a full PCT including a SERM is recommended after RAD-140

Ibutamoren MK-677

MK-677, although not a SARM but often found in the same category, is also known as Nutrobal or Ibutamoren. It is a selective agonist of the growth hormone receptor, so it works by raising your body’s levels of IGF-1.

Be aware that it also mimics your appetite hormone, so your appetite is likely to increase. Great for a bulking phase (or for hard gainers who struggle to get the calories in) but maybe not so good if you have a big appetite already. Best for bulking and adding mass, as well as boosting fat loss considerably.

  • Common dosage: 10mg-25mg per day
  • Half-life: 24 hours – full dosage can be taken once per day
  • Recommended cycle length: Long-term (minimum of 4 months for best results)
  • PCT? No, MK-677 is non-hormonal and doesn’t cause any suppression, PCT is not necessary

Cardarine GW-501516

Cardarine is actually a PPAR-delta modulator (not a SARM) that works by stimulating protein receptors which help the body create muscle tissue. But so many people group it in with SARMs that we thought it best to include it here. Effects of Cardarine include muscle gain, endurance and energy.

  • Common dosage: 7mg-20mg per day
  • Half-life: 16-24 hours – full dosage can be taken once per day
  • Recommended cycle length: 8-12 weeks
  • PCT? No – Cardarine is non-hormonal and will not affect your test levels

Andarine S-4

Andarine is one of the newer SARMs. S-4 is considered to be more potent when compared to other similar SARMs such as LGD-4033. It is very effective at lower doses and can significantly increase levels of lean muscle mass while reducing body fat levels. S-4 is renowned for increasing vascularity to give the ‘chiselled’, sharp look all bodybuilders seek to achieve.

Andarine is known for building muscle mass and bone density. Stick to lower doses to avoid side effects (some unwanted side-effects such as temporary night-blindness have been reported but only at very high doses!).

  • Common dosage: 25-75mg per day
  • Half-life: 3-4 hours – dosage ideally split 3 times per day for best results
  • Recommended cycle length: 8-12 weeks
  • PCT cycle: Yes, PCT is advised

S-23

One of the most potent SARMs on the market, some say that S-23 is the closest thing to conventional steroids that you can get. An excellent cutting compound, it boosts fat loss whilst offering impressive lean, dry gains. This compound is renowned for developing a dense, hard aesthetic with no water retention. If you’re looking for grainy-looking muscles, then you should definitely consider S-23. Often stacked alongside LGD-4033 or Andarine (S-4).

  • Common dosage: 10-20mg per day
  • Half-life: 6 hours – splitting the dosage twice per day is ideal
  • Recommended cycle length: 8-12 weeks
  • PCT cycle: Yes, PCT is advised

LGD-3303

LGD-3303 is one of the newer SARMs on the market and rapidly gaining a reputation to be one of the best SARMs for overall sheer mass and strength gains. It is also known for providing a noticeable muscular fullness despite being a dry compound.

LGD-3303 offers superb oral bioavailability, is non-steroidal and binds to the androgen receptor with an extremely high affinity and selectivity. The androgenic effects in the body are minimal at the effective dosage for muscle building purposes, thus making it a very promising SARM.

LGD-3303 has also shown to stimulate aspects of female sexual behaviour and can potentially serve as a potential therapy for women with sexual desire disorders.

  • Common dosage: 10-20mg per day
  • Half-life: 12 hours – splitting the dosage twice per day is ideal
  • Recommended cycle length: 8-12 weeks
  • PCT cycle: Yes, PCT is advised

A quick update here: LGD-3303 has now been patented by pharmaceutical company Ligand Pharmaceuticals Incorporated and is no longer available on the market.

LGD-3303 is a potent and highly selective androgen receptor full agonist in skeletal muscle, a classic target tissue for androgen action. By comparison, in the prostate and sebaceous glands, the compound is a weak partial agonist. The sparing of these non-target tissues by effective, pharmacologic doses of LGD-3303 provides a novel and potentially safer treatment for osteoporosis.

Source: Ligand Pharmaceuticals Incorporated

YK-11

YK-11 appears to be a super-SARM based on the reviews, while in reality, YK-11 is not a typical SARM. It is a new synthetic steroid based on 5-α-dihydrotestosterone (DHT) which is a stronger form of testosterone that targets androgen receptors in the prostate, sex organs, hair, and liver. YK-11 has gained a lot of interest in the bodybuilding world due to its potency and ability to rapidly build muscle mass with minimal side effects.

Research has shown that YK-11 inhibits myostatin. It induces muscle cells to make more follistatin which is a strong myostatin inhibitor. Myostatin (also known as growth differentiation factor 8) is a protein produced by muscle cells which acts on muscle cells to inhibit myogenesis. Research through the years shows that when you block myostatin, it allows for significantly more muscle mass.

There is little information available on the half-life of YK11. Anecdotal experiences tell us that YK11 half-life is relatively short, meaning it should be dosed multiple times per day for optimal results.

  • Common dosage: 5-15mg per day
  • Half-life: Approximately 4-6 hours – splitting the dosage twice per day is ideal
  • Recommended cycle length: 8-12 weeks
  • PCT cycle: Yes, PCT is advised

SARMs Stacks & Dosages

SARMs are used for lots of reasons: building muscle, adding mass, increasing strength, boosting energy and mood, as well as getting leaner without losing muscle mass. What happens when you stack two or more SARMs together in the same cycle? And how should you dose a stack of SARMs? Be mindful about the combination of SARMs in a stack, the duration of your cycle and the doses. And always take a post-cycle break which is equal to the length of your cycle. With any SARMs cycle, start on the lowest dose and only increase if you need to. Lowest is always best.

Bulking SARMs Cycle

The Advanced Bulking Stack is a combination of RAD-140, LGD-4033 and Ostarine for ultimate muscle mass, strength and size gains.

RAD-140 is a dry compound (this means no water retention) paired with LGD-4033 which does carry some water resulting in higher potential for muscle protein synthesis; ultimately aiding the bulking process.

The Ostarine is renowned for its healing properties particularly joint repair and bone health. It also offers a host of other impressive benefits; it can enhance tissue regeneration, reduce inflammation and support joint health.

These compounds also work synergistically with MK-677 to amplify results.

Recommended SARMs cycle length: 12 weeks

Cutting SARMs Cycle

The Pumping Iron Cutting Stack is designed to boost your metabolism and accelerate fat loss with a combination of S-4, Cardarine and Ostarine.

A must-have if you’re looking to take your physique to the next level, whether you’re bulking, dieting or looking for body recomposition.

This stack will effectively speed up results whilst improving your overall shape, fullness, hardness and even enhances your performance (endurance, stamina, energy levels and strength).

Recommended SARMs cycle length: 12 weeks

The Best SARMs Dosages

SARMs are widely known to be effective at helping build muscle, strength, mass, and endurance whilst also helping you lose body fat. As with any drug or compound, be sensible and smart about how you use SARMs.

Always check out the recommended dose and always start low. Not only does this give you somewhere to go (if you start high, you leave yourself with nowhere to progress) but it also means you can assess the results at low doses. At lower dosages, you may be able to avoid the need for any PCT. Be smart with your SARMs cycle and see what amazing benefits you still get from SARMs.

What’s the Best PCT for SARMs?

Although PCT is a very subjective matter, it’s often recommended to run a PCT such as Pro PCT (6-OXO).

Pumping Iron Pro PCT (6-OXO) is an advanced SARMs and prohormone PCT that contains 6-OXO, a potent aromatase inhibitor which should only be used by experienced users of SARMs and prohormones. This supplement is intended for male athletes only and shouldn’t be used by women. PRO PCT can be used to prevent estrogen related side effects on-cycle as well as a powerful recovery agent for post cycle therapy (PCT)

  • Strongest aromatase inhibitor on the market
  • Increases lean muscle mass
  • Reduces conversion of testosterone to estradiol
  • Supports muscle retention
  • Increases testosterone:estrogen ratio
  • Suitable for vegans (HMPC Veg Cap)
What is RAD-150 (TLB-150 Benzoate)?

What is RAD-150 (TLB-150 Benzoate)?

If you’ve researched the SARM RAD-140, then you may be wondering: what is RAD-150 (TLB-150 Benzoate)? 

RAD-150 is the latest compound gaining all the attention when it comes to research chemicals and the bodybuilding industry. With its predecessor RAD-140 taking the top spot when it comes to best-selling SARMs, everyone is wondering how RAD-150 compares and why its rapidly gaining the same level of popularity.

What is RAD-150 (TLB-150 Benzoate)?

Selective androgen receptor modulators (SARMs) are tissue-selective research drugs similar to steroids. But unlike steroids, SARMs don’t cause systematic effects. That means they only bind to muscle tissue androgen receptors and leave the rest of your body alone.

The latest SARM to hit shelves in the UK is RAD-150, also known as TLB-150 Benzoate. This research chemical is an anabolic ester. That means it better mimics the role of natural testosterone in the body as compared to non-esterized SARMs.

If you’re curious about RAD-150’s potential benefits and what sets it apart from other SARMs, keep reading for everything you need to know.

What Are Research Chemicals?

You may know that SARMs such as RAD-150 are research chemicals. What you may not know is what that actually means.

Research chemicals are compounds scientists use in pre-clinical or clinical research. For example, scientists first discovered SARMs when they were researching chemicals for prostate cancer treatment.

The thing about research chemicals is that they were originally intended for laboratory settings and not for human consumption. When you purchase SARMs from Pumping Iron, you’re consenting to the legal use of these products.

How Does RAD-150 Work?

Like all SARMs, RAD-150 binds to androgen receptors in skeletal muscle tissue. When these receptors get activated, they cause a host of downstream effects. These effects boost muscle hypertrophy, which is the same process that occurs during weight lifting.

Is RAD-150 Safe?

A 2020 study of SARM research chemicals found that many products on the market aren’t what they say they are. The researchers found that some products studied:

  • Claimed to contain active ingredients but these ingredients weren’t present in the supplements
  • Included prohibited analytes that weren’t listed on the label
  • Lacked information about the product’s safety and toxicity

This is why you should always buy research chemicals from a reputable brand. To ensure your safety, only choose SARMs from brands you can trust, like Pumping Iron.

The Benefits of RAD-150

RAD-150 provides many of the same benefits as other SARMs. For example, this research chemical can encourage lean muscle growth and reduce body fat. RAD-150 may also speed up muscle regeneration after a workout.

That’s not all, though. Some users also report increased libido and improved sexual performance after using RAD-150.

RAD-150 Side Effects

So far, the most touted side effect of RAD-150 is insomnia. This makes sense considering this research chemical has a longer half-life. Skipping days between doses or taking smaller doses may help reduce or eliminate this side effect.

The Difference Between RAD-150 and RAD-140

If you’re familiar with SARMs, you may be wondering: isn’t there a RAD-140 research chemical on the market already? RAD-140 or testolone first emerged as a safer form of Testosterone replacement therapy. It’s also a potential breast cancer tumour suppressor.

RAD-140 is the predecessor to RAD-150. They’re highly similar chemicals that look almost identical, giving them many benefits in common. For example, RAD-140 and RAD-150:

  • Enhance muscle gains
  • Boost fat loss
  • Improve strength

So, what’s the difference? As we’ve mentioned, RAD-150 is an anabolic ester. RAD-150’s structure includes an additional benzoate ester group, which offers even more benefits like the ones we’re telling you about next.

Esterized vs Non-Esterized SARMs

Esterification is the process of adding an ester group to a compound. Researchers produce esters through a chemical reaction, usually of an acid (e.g., carboxylic acid) and an alcohol. This produces a more alkaline product.

In RAD-150, the increased alkalinity makes for a more stable compound. It also makes RAD-150 more similar to natural testosterone. That means it can bind better to androgen receptors.

Because RAD-150 is an anabolic ester, it tends to act faster and last longer than other SARMs. Anabolic compounds have increased bioavailability, meaning your body absorbs them quicker. They also have a longer half-life, which allows your body to eliminate them slower.

This is why you can expect RAD-150 research chemicals to take effect rapidly and last for 48 hours or longer. Overall, RAD-150 offers way more bang for your buck than non-esterized RAD-140.

Stacking RAD-140 and RAD-150

Stacking SARMs together or alongside similar products produce synergies. Synergy refers to the fact that two chemicals together can sometimes produce more robust effects or added benefits than if those chemicals are used alone.

For example, stacking may:

  • Speed up recovery times
  • Boost fat loss
  • Enhance bulking cycles

RAD-140 and RAD-150 are ideal for stacking. Stack these SARMs with growth hormones or other bodybuilding supplements to harness these synergies and more.

Where to Buy RAD-150 (TLB0150 Benzoate)

Selective androgen receptor modulators can help you build strength and lean muscle while reducing fat content.

RAD-150 (TLB-150 Benzoate) is the latest SARM on the market. It promises even more impressive benefits. This includes a quicker onset and longer-lasting effects than any other SARM on the market.

Are SARMs Legal?

Are SARMs Legal? (5 Olympic Athletes Banned)

Are SARMs Legal? Confused about Selective Androgen Receptor Modulators and wondering are SARMs legal in your country? We’ve got all the answers.

Are SARMs banned where I live? Can I use SARMs and compete in sport? These are some of the questions you might have if you are considering using SARMs to build muscle, lose fat, or boost your training performance.

SARMs are a relatively new type of compound, so it’s not surprising people have a lot of questions. We’ve gathered the answers together here in one essential article, so you have all the information in one place.

SARMs As Supplements

In general, SARMs are not considered illegal substances. In most countries are classed as “investigatory chemicals”. This might sound as if SARMs are therefore legal to use as sports supplements but this is where you need to be careful.

Firstly, you need to be certain of your own country’s regulations around SARMs (we will look at these in a moment). Second, you need to understand the difference between a compound being legal as an “investigatory chemical” (or research chemical) and as a food supplement or medicine.

To understand more about this distinction (and to get the current status of SARMs where you live), keep reading.

SARMs Banned In Sport

SARMs – selective androgen receptor modulators – are often used as performance-enhancing drugs by bodybuilders and other athletes. The list of effects includes strength gains, muscle mass, fat loss, endurance, and recovery.

The World Anti-Doping Agency (WADA) was founded by the International Olympic Committee to bring consistency to anti-doping rules, regulations and policies worldwide. What does WADA say about SARMs? You’ll need to know this information if you intend to compete in any drug-tested sport (including drug-tested bodybuilding federations or powerlifting competitions).

SARMS are currently prohibited by WADA, who placed them on their “prohibited at all times” list in 2008.

But what does this mean for those of you who want to use SARMs for your own training, and do not intend to compete in drug-tested sport?

Are SARMs Legal In Your Country?

Let’s look at the legal and regulatory status of SARMs (at the time of writing) in your country.

Are SARMs Legal in the UK?

The United Kingdom has no current legislation restricting SARM. It is legal to buy and sell SARMs in the UK but selling them as a food supplement or as medicine is illegal.

Are SARMs Legal in the USA?

The United States has no current legislation restricting SARMs, but this might change under the Controlled Substances Act if S. 2742 (115th): SARMs Control Act of 2018 (a bill to amend the Controlled Substances Act to more effectively regulate selective androgen receptor modulators).

Norway, Denmark, Sweden

SARMs may be seized if found by customs

Ireland

There is no current legislation to control SARMs use, but SARMs may be controlled on import.

Australia?

SARMs will likely be seized on import.

Canada

There is no current legislation to control SARMs use, but SARMs may be controlled on import.

France, Germany, Italy

There is generally no issues with import of SARMs.

Why Were SARMs Originally Developed?

SARMs were developed as medical drugs to treat various conditions, including those where muscle wasting and loss of bone density becomes a problem. The first SARMs were developed in the 1940s when researchers worked out how to modify the structure of testosterone molecules.

These early SARMs were used to treat conditions that weakened the body (by loss of muscle mass), caused a loss of strength and even organ failure. But they were considered steroidal drugs because they were derived from testosterone. Even back then, these SARM drugs had the ability to help patients rebuild muscle mass, regain strength and retain mass when they would usually have lost tissue.

In the 1990s, the current breed of SARMs began to be developed. These drugs were non-steroidal, safer than the earlier SARMs and largely without side-effects. Since then, a lot of work has been done to make SARMs more bioavailable, less toxic and generally safer.

A number of SARMs are in the clinical trial stage, but none have yet got to late-stage clinical trials (phase IV) on humans – this would give us the assessing the use of SARMs in the general public and looking at long-term effects. A lot of the big pharma and life science companies are invested in researching and developing SARMs though, so it might not be long until we see SARMs in human clinical trials.

The SARMs you can get today bind to certain receptors in certain cells, so they only impact specific areas of the body. This selective characteristic makes them powerful for muscle gain, strength gain, and retention of lean muscle tissue.

Athletes Banned For SARMs Use

Some of you competitive athletes may be wondering, are SARMs legal in sports? SARMs are banned by WADA and many sports and sporting organisations adhere to the WADA list. This includes all of the sports NGBs who make up the Association of Summer Olympic International Federations, the Commonwealth Games Federation, the IFBB for bodybuilding, and the IPF for powerlifting. You can see all the current signatories to the WADA list here.

Thomas Goller, German hurdler, was banned for 2 years in 2010 for use of Boldenone and SARMs.

Also in 2010, Bobby-Gaye Wilkins, the Jamaican sprinter, was banned from competitive athletics for 2 years after testing positive for the SARM Andarine.

Russian long jump athlete Svetlana Biryukova received a 2-year doping ban in 2014 for SARMs use.

In the same year, two-time Olympian Martin Maric (discus throw athlete for Croatia) was suspended from track and field for 2 years after testing positive for the SARM Ostarine.

Also in 2014, the race walker Irina Yumanova (Russia) was banned for 2 years for SARM use. Her coach – Viktor Chegin – was banned for life from all sport-related activities in 2016 after a number of his athletes were disqualified for doping-related offences over a period of 10 years.

Why Are SARMs Banned By WADA?

Getting back to the “prohibited at all times” status on the WADA list, why does the World Anti-Doping Agency ban SARMs for use in drug-tested sport, when they are no illegal for general use?

SARMs work! SARMs can be very effective as performance enhancers, so it stands to reason that WADA – which aims to stamp out any “unfair play” – would ban SARMs for giving an unfair advantage.

Even if you don’t need to heed WADA’s legislation, you should take a second to think about their decision over SARMs. The very fact that SARMs are banned by WADA tells us that these compounds have a definite impact on athletic performance and on other factors like muscle mass, strength, power and endurance.

SARMs should not be taken lightly. If you choose to use SARMs, always get them from a trusted, professional source, and always take them as recommended. In almost all cases, SARMs deliver amazing results even at small doses. There is no need to stray above and beyond the recommended dosage or frequency.

Best Dosage for MK 677: Ultimate Guide for Mega Mass

Best Dosage for MK 677: Ultimate Guide 2021

Discover the reason this compound has been making waves in the bodybuilding industry but most important of all, the best dosage for MK 677.

MK-677 also known as Ibutamoren is a ground-breaking compound often classed into the same category as SARMs, although technically it isn’t actually a SARM. MK677 is a growth hormone secretagogue which essentially elevates your own natural production of growth hormone which has a whole host of health and fitness benefits all-round.

Not only does Ibutamoren improve recovery, muscle mass and fat loss, it even has remarkable anti-ageing properties as well as improving skin texture, hair and nails.

People are getting great results using MK-677 but obviously their results depend on a lot of factors including how they research it and their commitment to diet, training and recovery.

Although there is plenty of information about MK-677, we cover the different ways in which it can be researched and the best dosage for MK 677 for different purposes.

What is MK-677?

MK-677 is a growth hormone secretagogue – basically, it is a compound that encourages the body to secrete more growth hormone. Now you already know that growth hormone (GH) is a powerful hormone which is highly anabolic, helping you to grow new tissue (including muscle tissue) and retain more lean muscle when you are dieting or training hard.

Like most SARMs and similar compounds, MK 677 started life as a manmade compound developed as a potential medical aid. In this case, it was developed and studied as a possible alternative for patients with hormonal deficiencies and problems related to a lack of bone density.

Early studies suggested MK 677 could reverse catabolism (tissue breakdown) to boost bone density and the density of other tissues including muscle. It was also found to aid sleep and mental function in some study subjects.

Most notably – for us, anyway – MK 677 could boost the body’s production of growth hormone but without suppressing any of the natural hormonal biological processes. This meant much fewer side effects than anabolic steroids.

How Does MK 677 Work For Muscle Gain?

Although MK 677 isn’t a SARM, it really can help you boost muscle mass, strength, and density if you are already training well in the gym. It does this by encouraging your body to secrete higher levels of two key anabolic hormones: growth hormone (GH) and growth factors (IGF-1).

How? By imitating the hormone ghrelin (which stimulates appetite) and binding to ghrelin receptors. This has a number of beneficial knock-on effects including cognitive strength, better mood, a healthier appetite and gains!

One important thing to know is MK 677 doesn’t impact your body’s natural hormone levels (like anabolics tend to do), so you won’t need to do a PCT (post cycle therapy) if you use MK 677.

7 Benefits of MK-677

Here are the top 7 benefits for bodybuilders and strength athletes.

1 Build muscle mass

MK 677 can help your body pack on muscle mass by encouraging more growth hormone and IGF-1. These are two highly anabolic hormones which support better MPS (muscle protein synthesis), increase nitrogen retention, and boost your strength.

2 Minimise catabolism, retain muscle mass when dieting

MK 677 can also reduce muscle loss, which is a real problem when dieting for fat loss. The more muscle you can retain, the better you will look when you are lean. Think that full, dense look rather than a scrawny over-dieted look!

3 Faster fat loss

The anabolic hormones we already mentioned (GH and IGF-1) can actually help you torch through body fat, making MK 677 a useful compound for dieting or recouping. Just remember, you can’t use it if you are entering a tested competition as it is banned under WADA rules.

4 Increased bone density

Bone density might not sound like a priority for bodybuilders, but it should be. After all, what do you think is the foundational structure for all that muscle mass? Your skeleton. A healthy, strong skeleton means you can lift heavier and put more stress through your joints, ultimately meaning you can build more muscle – and keep training later into life.

5 Improved training recovery

Deep restful sleep and the ability to recover between training sessions are key components of optimal recovery. MK-677 has neuroprotective benefits, meaning you are more likely to have a great night’s sleep with plenty of REM sleep (key for recovery). As you know, good sleep means better training motivation, more energy, better performance in the gym and even the ability to stay away from junk food and snacks!

6 Skin condition and tightness

Any competitive bodybuilder will tell you that skin condition is a real bonus. Great skin makes muscles look even better. Even low doses of MK 677 can have a positive impact on skin cells, helping you look full and healthy.

7 Mood, focus, and training motivation

MK 677 can boost your brain function, helping you feel better and perform better. This means more energy and better focus for the gym as well as a better overall outlook – all of which will help you stick to your training and diet programme.

Understand The Side Effects Of MK 677

Now, you must understand that MK 677 is a manmade compound which was first developed as a possible medication. Therefore – like most medications – it can have side effects. The chance of these is greatly heightened if you incorrectly dose MK 677 which is why we’ve written this article about the best dosage for MK 677.

The good news is that MK 677 shouldn’t suppress your natural testosterone levels if you are otherwise healthy. So you won’t need to run a PCT.

  • Muscle cramps – you may experience some mild muscle cramps using MK 677
  • Bigger appetite – this is quite likely at higher dosages as MK 677 stimulates ghrelin
  • Water retention – this can happen at the start of a cycle but tends to subside after 2-3 weeks
  • Reduced insulin sensitivity – may occur if you are not completely healthy
  • Increased blood pressure – only likely in unhealthy individuals

In short, we advise you to always exercise caution with any compound. If in doubt, do not use it. Know the risks, do your research, and make an informed decision.

Best Dosage for MK 677

The first thing to mention is that MK-677 has a half-life of 24 hours, which means you can take it just once per day but some people do prefer to split the dosage.

As MK 677 can spike GH levels, some people find this makes them feel tired. Anecdotally, some people have found that splitting the dosage can help to reduce some side effects such as fatigue.

The options are:

  • Split your dose in two, take one during the day and one before bed
  • Take your daily dose in one go, before bed
  • Tkae your daily dose in one go, upon waking

The best dosage for MK 677 will depend on your goals and the main purpose of your research. This compound has benefits even at low doses, so there is absolutely no need to take high doses, contrary to popular belief.

Always start with the lowest dosage (usually half of your final dosage) for the first week to assess your response.

MK-677 is a long-term compound that will take a few weeks to see results because MK 677 is manipulating your natural GH levels. Results will take time to appear to the eye but will be sustainable, quality results.

Dosage for MK 677 (Gaining Mass and Boosting Fat Loss)

The best dosage for MK 677 when looking to gain muscle mass and lose body fat is between 20-25mg per day.

Some users have reported better results at higher doses of around the 25mg range buta higher dosage will also tend to exhibit more pronounced appetite and lethargy. Lowering the dosage and finding what works best for you is always the best protocol.

This 1998 double-blind, randomised human study shows impressive results in a group of males given Ibutamoren MK-677 – they showed increased lean mass, GH secretion, and even energy expenditure in just two months. That same study showed that serum IGF-I increased by approximately 40% with Ibutamoren MK-677 treatment.

See our MK-677 Before and After Photos.

Dosage for MK 677 (Anti-Ageing, Recovery, Injury Repair, Healing)

Ibutamoren works well at lower doses. The average is around 5mg and this is enough to produce numerous GH pulses over the course of a day. For anti-ageing and recovery, the best dosage for MK 677 is as low as 5-10mg per day, maintained long-term.

Along with benefits to bone health, MK-677 is renowned for its anti-ageing properties because HGH helps to promote growth and recovery in older cells.

Coupled with the anti-inflammatory effects of IGF-1, will help to promote cell health and prevent breakdown. Furthermore, higher IGF-1 levels also help to maintain brain development.

Does MK-677 Require a PCT?

Stenabolic (SR-9009) is not suppressive and does not generally require a PCT.

Stenabolic SR9009 - The Secret Fat Loss Wonder Drug

Stenabolic SR9009 – The Secret Fat Loss Wonder Drug (Updated 2021)

We write about SARMs at Pumping Iron Store but this is something a little different. Although you will often hear Stenabolic SR9009 talked about in the same conversation as SARMs, it is not, in fact, a SARM. This article will tell you about Stenabolic, why it was developed, what it is, the benefits and side effects and what to expect.

Although Stenabolic SR9009 was developed to study the circadian rhythm, studies have shown this drug to improve the overall health and quality of life of anyone who uses it. Dubbed as ‘exercise in a bottle’, research on Stenabolic shows that it can help to lose weight, decrease cholesterol, inflammation and even anxiety.

What Is Stenabolic SR9009?

As we have briefly mentioned, Stenabolic is not a SARM. It is a compound that was developed by researchers in a bid to treat or manage medical conditions. Stenabolic is a REV-ERB (specifically a REV-ERBα antagonist) which means it impacts the metabolism, including the circadian rhythm. It’s pretty complicated to explain, but here’s our best layman’s version:

Your body’s circadian rhythm is a pattern your system cycles through every 24 hours. Experts think it is linked to sunrise and sunset. It governs things like sleep, waking, energy levels, and hunger. Part of the cycle that keeps your circadian rhythm going involves “switching” genes on and off throughout the 24-hour cycle.

Stenabolic was initially developed for its effects on the circadian rhythm and was found to improve mood, control anxiety, reduce inflammation, and even have a positive impact on weight gain. Sounds good for bodybuilding, right?

Stenabolic was also found to increase the activity of REV-ERB nuclear hormone receptors, and this boosts the bioavailability of nutrients in your body. For us as bodybuilders, this means better nutrient uptake and more of the nutrients we eat gets to our muscle tissue.

One thing you must consider about SR9009 is that there is no human research on it. There’s plenty of research from animal studies (especially mice studies) but none on human subjects. There is plenty of anecdotal evidence and feedback from guys who use it to augment their training. So be sure to go into this with your eyes open and full awareness of the lack of human research.

How Does Stenabolic SR9009 Work?

The processes behind SR9009 are pretty complicated and well beyond a short article here. If you’re the deep-dive research kind of reader, take a look at this paper published in Nature Reviews Drug Discovery in 2014 or this 2016 paper published in the International Journal of Molecular Sciences.

SR9009 has a significant impact on REV-ERBA, which impacts circadian control and has knock-on effects on the immune system, sleeping patterns, energy production, and general activity.

Activation of Rev-ErbA-α by SR9009 increases exercise capacity by increasing mitochondria counts in skeletal muscle.

REV-ERB is particularly influential in the tissues of the muscles, body fat, and liver. This suggests it could help boost fat burning, “switching off” the genes which store fat and increasing the number of mitochondria in the muscles.

OK, that’s a lot of scientific talk (and a couple of papers for you to look at). But what about the real-life stuff – how does SR 9009 benefit bodybuilders and people who want to get big, ripped, and lean?

Benefits of Stenabolic SR9009

  • Increases oxygen consumption
  • Prevents the creation of new fat cells in the liver
  • Increases the number of mitochondria in the muscle cells
  • Increases glucose and lipid metabolism
  • Decreases triglyceride levels in the blood
  • Reduces cholesterol breakdown in the liver
  • Promotes fat loss through glucose consumption
  • Regulates blood sugar levels
  • SR9009 has even been used to treat type-2 Diabetes
  • Delays the ageing process
  • Reduces inflammation
  • Decreases anxiety

1 Weight loss & fat loss

SR9009 has been shown to increase weight loss even without altering dietary intake. It has also been shown to reduce amounts of free fatty acids, triglycerides, and cholesterol. It could be great as a fat burner when you’re dieting or trying to get rid of that last bit of body fat.

2 Mood & energy

SR9009 is thought to be able to affect sleep patterns, which is beneficial to recovery and general health. It has been shown to increase energy levels and could even be used to increase wakefulness. Some studies also suggest SR 9009 could reduce anxiety.

3 Endurance

SR9009 has been shown to increase the total amount of mitochondria, which has a direct impact on endurance levels for physical activity. More endurance = more training = more gains.

4 Reduced inflammation

Inflammation can pose a big problem for bodybuilders who train hard, and Stenabolic SR9009 may be able to tackle this issue (by reducing TNF alpha in the body – these cells are a key player in systemic inflammation).

Does Stenabolic Have Side Effects?

We don’t know of any side effects with Stenabolic SR 9009 but there haven’t been any human studies so it’s difficult to say this with total confidence.

Stenabolic has shown no liver toxicity.

However, we do know that SR9009 doesn’t impact the body’s natural hormone levels so you won’t need to run a PCT if you use Stenabolic.

Best Dosage & Cycle Length for Stenabolic

Stenabolic has a half-life of 4 hours so you’ll need to split your total daily dose into 2-3 doses per day. So, if you’re taking 20mg/day, take 5mg every 4 hours (say, at 8 am, 12 pm, 4 pm, 8 pm).

Start at 10mg-20mg/day (maximum) and increase only to 30mg if you need to.

Most will run Stenabolic SR9009 cycles of 8-12 weeks, followed by the same time off.

Does SR-9009 Require a PCT?

Stenabolic (SR-9009) is not suppressive and does not generally require a PCT.

Best Testolone RAD-140 Dosage

RAD-140 Dosage and Complete Cycle Guide for Maximum Gains

Arguably one of the most talked-about compounds on the bodybuilding scene today, we’re going to look at the optimum RAD-140 dosage and cycle protocol that will give you the gains that you’re looking for.

RAD 140 – also known as Testolone – is a popular SARM with benefits including muscle gain and fat loss. But, as with any compound, it’s important that anyone considering to research Testolone knows the best RAD-140 dosage and cycle protocols to take. So here is everything we currently know about what dose to use, cycle length and stacking methods for best results.

What is RAD-140?

Testolone was developed as an investigational drug which might be able to treat muscle wasting diseases and help patients build muscle. It is a SARM (selective androgen receptor modulator), which works by selectively binding to some androgen receptors in the body – specifically those in muscle tissue and bone tissue. These receptors “talk to” the steroid hormones called androgens, including testosterone.

RAD 140 is thought to help increase muscle mass, boost fat burning and fat loss, and may even have neuroprotective benefits. It is also popular with men who are experiencing low testosterone levels and want to boost their physical performance and physique alongside getting their test levels up.

However, there have been no human studies on RAD 140 so far, and the long term risks and benefits are unknown. As with any SARM, do your research.

Like all SARMs, RAD 140 is on the WADA banned list so you should not use it if you are going to compete in tested events or take part in professional sports.

5 Benefits of Testolone

SARMs are popular with bodybuilders and people wanting to get bigger, stronger, and leaner. RAD 140 is no different in that respect. Here are the top benefits of Testolone for people who train in the gym.

1 Muscle growth

RAD 140 boosts the body’s development of proteins and muscle cells and can help stimulate muscle growth. Because SARMs are selective in the receptors they bind to, RAD 140 shouldn’t give unwanted side effects.

2 Repair and recovery

RAD 140 has been found to trigger the MAPK pathway which plays a part in protecting and repairing cells, and some users report better sleep. In one study scientists were able to use RAD-140 to activates receptors in damaged sections of the brain. The resulting reaction was a signal known as the MAPK pathway which is known to protect brain cells.

3 Bulking

Some SARMs are stronger and better for muscle gain, others are good for cutting. RAD 140 seems to be a better choice for a bulk.

4 Brain health

RAD 140 interacts with androgen receptors, and androgens are important for protecting brain health. RAD 140 may be able to help improve memory and cognitive health.

5 Fat loss

RAD 140 has been shown to improve cholesterol levels and boost muscle mass which can also help you burn fat and get leaner for better body composition.

With all these potential benefits, it’s no surprise bodybuilders are attracted to Testolone for training, fat loss, muscle gain, and recovery.

Best RAD-140 Dosage and Cycles

The lack of human studies means it’s difficult to give specific advice on how to dose RAD 140, but we can tell you what other people do. Anecdotal evidence is currently the best source of information regarding the research of SARMs. Below are some examples of popular RAD-140 dosage and cycle research methods.

Male esearchers begin at a dose of 10mg/day and increase to no more than 30mg/day.

Although RAD-140 is not recommended for women, those who do decide to research this drug will start with 5mg/day and increase to no more than 10mg/day.

A cycle length will generally last between 8-12 weeks following by a 4-week PCT and “off-cycle” break period.

RAD-140 is suppressive. It is critical that you are familiar and prepared with your PCT protocol before you start your cycle to avoid unwanted side-effects.

Some people stack Testolone with other SARMs, popular choices seem to be Ligandrol (for bulking), Ibutamoren, Ostarine, or Cardarine (for cutting).

Best RAD-140 Dosage for Bulking

The best RAD-140 dosage for gaining mass is 20mg-30mg/day for 12 weeks, with an off-cycle of 12 weeks. This lengthen cycle means you get maximum benefits of the strength gains, so you can train harder and lift more for the duration of a successful bulk. You’ll avoid most of the training fatigue typically experienced during a serious training block, and consequently, you’ll be able to keep training harder and increase your lifts throughout your bulking cycle.

RAD-140 Bulking Cycle

Testolone RAD-140 – 10mg per day, dosed once a day in the a.m.
Ligandrol LGD-4033 – 10mg per day dosed once a day in the a.m.
Ostarine MK-2866 – 25mg per day, dosed once a day in the a.m.

Best RAD-140 Dosage for Cutting

Testolone can also be used on a cut. Remember, it was originally developed to help prevent muscle wastage – and this is exactly what you want to do when you are in an extended calorie deficit. If you can hang on to more muscle when you are dieting, not only will you look better but your metabolic rate will stay higher.

The best RAD-140 dosage for cutting is slightly lower than that of a bulking phase if you are in a caloric deficit and primarily aiming for its anti-catabolic properties.

RAD-140 Cycle for Cutting

Testolone RAD-140 – 10mg per day, dosed once a day in the a.m.
Cardarine GW-501516 – 20mg per day, dosed once a day in the a.m.
Stenabolic SR-9009 – 30mg per day, 5mg split doses 2-3 hours apart

Best RAD-140 Dosage for Recomposition

Body-recomposition allows a person to build lean muscle mass whilst dropping body fat simultaneously. We said it here, yes it’s possible to lose body fat and gain muscle at the same time. With that in mind, the RAD-140 dosage is higher than on a ‘cut’ and adding Andarine into the mix to maximise lean gains.

RAD-140 Cycle for Body-Recomposition

Testolone RAD-140 – 20mg per day, dosed once a day in the a.m.
Cardarine GW-501516 – 20mg per day, dosed once a day in the a.m.
Stenabolic SR-9009 – 30mg per day, 5mg split doses 2-3 hours apart
Andarine S-4 – 50mg per day, 25mg in the a.m. and 25mg 4-6 hours later

Best RAD-140 Dosage for Strength

This stack makes use of the powerful synergistic effects of RAD-140 and S-4 when stacked together. Throwing Cardarine into the mix further maximises performance, which ultimately carries over to strength gains.

RAD-140 Cycle for Strength & Power

Testolone RAD-140 – 20mg per day, dosed once a day in the a.m.
Cardarine GW-501516 – 20mg per day, dosed once a day in the a.m.
Andarine S-4 – 50mg per day, 25mg in the a.m. and 25mg 4-6 hours later

Best RAD-140 Dosage for Lean Gains

This stack is the same as the re-composition stack but your own diet manipulation is what comes into play. Increasing your calorie and/or protein intake will optimise results for lean mass gains, increasing muscle protein synthesis whilst mitigating fat gain.

RAD-140 Cycle for Maximum Lean Mass Gains

Testolone RAD-140 – 20mg per day, dosed once a day in the a.m.
Cardarine GW-501516 – 20mg per day, dosed once a day in the a.m.
Stenabolic SR-9009 – 30mg per day, 5mg split doses 2-3 hours apart
Andarine S-4 – 50mg per day, 25mg in the a.m. and 25mg 4-6 hours later

Does Testolone Need A PCT?

All SARMs have the potential to suppress the body’s natural hormone levels and impact testosterone production, to varying degrees.

RAD-140 is one of the more potent SARMs and it is suppressive. It is critical that you are familiar and prepared with your PCT protocol before you start your cycle to avoid unwanted side-effects.

cardarine review photos blog

Cardarine Review: Your Guide To GW-501516

Read our Cardarine review to understand what it is and why it seems to be shaking things up in the bodybuilding industry! What exactly is Cardarine and what are the benefits for muscle gain and fat loss?

Cardarine (also known as GW 501516) is a very interesting compound that you might have seen cropping up more and more in the bodybuilding and fitness community recently. It is often referred to as a SARM, mainly because it’s often found in the same category as other SARMs and often stacked alongside them. GW actually a PPAR-delta activator. In this article, we discuss what this means, how GW501516 works and why many bodybuilders are turning to Cardarine to help them gain muscle, lose fat, improve their physique and train harder in the gym.

What is Cardarine GW 501516?

Although some people call Cardarine a SARM, it is not actually a selective androgen receptor modulator. Cardarine is actually a PPAR-delta activator but it works in similar ways to a SARM and that’s why bodybuilders and gym trainees are attracted to it for muscle gain, strength gain and fat loss.

Cardarine was originally developed as a potential medical asset for prevention of tumours but it soon showed other benefits: it could help reduce body fat, control body weight, raise the metabolic rate, increase rates of muscle growth, and boost endurance. No wonder bodybuilders are keen to take a closer look!

Like all drugs of its type, Cardarine is banned by WADA and can not be used in professional sport or in any tested competitions – that includes drug tested bodybuilding contests.

Cardarine Review Alongside Trenbolone

Cardarine pairs well with Trenbolone because it can counteract a lot of the negative side effects such as night sweats, reduced endurance, loss of libido, shortness of breath, increased blood pressure and a poor balance between cholesterol levels (high LDL and low HDL).

Tren severely reduces your cardiovascular potential so using Cardarine alongside a Tren cycle makes a very noticeable improvement. Cardarine improves endurance levels and helps athletes to push further, recover faster and greatly improves their cardiovascular health.

Studies have shown that GW-501516 has a positive impact on the balance between HDL and LDL cholesterol which can offset the negative side effects of Trenbolone.

In one study, Cardarine increased HDL cholesterol and decreased triglycerides, insulin, and LDL cholesterol, which may altogether decrease the risk of heart disease.

A number of studies have also shown that Cardarine helps to lower high blood pressure.

Cardarine Review – Before & After Photos

Cardarine is one of the best compounds when it comes to boosting fat loss and increasing your endurance, energy and stamina. This PPAR modulator has been proven through valid research to have many health benefits but its performance benefits are its top advantages.

When it comes to fat loss, you’ll notice a major difference as well as an increase in vascularity as Cardarine promotes the burning of fat as a source of fuel. You’ll also see dramatically reduced recovery times after working out, and even a boost in your mood.

cardarine before and after
Cardarine 12-week cycle before and after photos
  • Incredible endurance enhancement
  • Dramatically reduced recovery time
  • Works from the first dose
  • Improves your mood
  • Enhances fat loss
  • Ideal for interval/cardio training
  • Stackable with other SARMs
  • Is NOT a stimulant and doesn’t increase heart-rate
  • Can be stacked with any other fat burners for maximum fat-burning potential

Read our blog to see more SARMs Before and After Photos.

How Does Cardarine Work?

Cardarine GW 501516 binds to the PPAR-delta nuclear receptors which are mostly in your muscles and stimulates some of the genes which govern how your body uses energy. By doing these two things, Cardarine can:

  • Help you burn more body fat – by preventing fatty acid chains from being formed, and therefore stopping your body from storing fat, so your system has to use stood fat for energy
  • Preserve existing muscle mass – when you are in an energy deficit and your body is forced to use fat for fuel, Cardarine can also protect muscle mass from catabolism
  • Faster recovery – Cardarine may increase the amount of oxygen which gets to your muscles, helping you recover from training sessions

Cardarine Review for Bodybuilding

1 Fat burning

Cardarine can help you burn more body fat by encouraging your body to use stored fat for fuel, by stimulating glucose, and by activating some of the genes involves in fat burning.

2 Bulking and cutting

Cardarine can be stacked with other SARMs to encourage fat loss, boost training performance, and help you maintain muscle mass when dieting – ideal for cutting and bulking cycles.

3 Brain health

Cardarine can improve blood flow to the brain, protecting brain vessels, boosting the growth of nerve cells, and reducing problematic inflammation.

4 Training endurance

Cardarine stimulates your body’s use of glucose for fuel, which means you can probably train longer and harder. More training = more muscle gain!

5 Muscle growth

Cardarine activates the PPAR-delta which boosts muscle fibres, gives you increased energy and means you can train for longer too.

6 Heart health

Cardarine may have a protective benefit for your blood vessels, reducing oxidative damage and plaque build-up, and increasing your levels of nitric oxide.

How To Dose Cardarine

Cardarine is kind of an all-rounder, you can use it for cutting or bulking cycles. It has a half life of 16 hours, so you will need to split your daily total dose into two doses. Start with 10mg/day (5mg twice per day), ideally with one dose 2-3 hours before you train. Run Cardarine for a maximum of 12 weeks, followed by a 6 week off-cycle break.

Can You Stack Cardarine?

A Cardarine Review wouldn’t be complete without some stack suggestions, so here they are! GW can be stacked with most other compounds. It mitigates fat-gain during bulking cycles, increases fat-loss during cutting cycles, and enhances endurance and performance all-round. Here are the most popular SARMs stacks:

Body-Recomposition Stack

  • Cardarine GW-501516
  • Ligandrol LGD-4033
  • Andarine S-4

Cutting Stack

  • Testolone RAD-140
  • Cardarine GW-501516
  • Stenabolic SR-9009
  • Andarine S-4

Strength Stack

  • Testolone RAD-140
  • Cardarine GW-501516
  • Andarine S-4

Bridging Stack

  • Andarine S-4
  • Ostarine MK-2866
  • Cardarine GW-501516
  • Stenabolic SR-9009

Endurance Stack

  • Cardarine GW-501516
  • Stenabolic SR-9009

Bulking Stack (with minimum fat-gain)

  • Cardarine GW-501516
  • Ostarine MK-2866
  • Ligandrol LGD-4033
  • Testolone RAD-140

Does Cardarine Have Any Side-Effects?

Like any compound, you should be sensible about using Cardarine. This includes looking out for side effects. Cardarine won’t suppress your natural hormone levels. It is always recommended to start off with lower doses and assess response and adaptation. If there is anything we haven’t covered in this Cardarine Review, see our Guide to Cardarine for more information.

andarine s4 benefits dosages blog

Andarine S4: Benefits, Dosages (Complete Guide)

Andarine (also known as S4) is a powerful selective androgen receptor modulator which can support muscle growth, mass, and density. This article will tell you everything you need to know about this increasingly favourable compound.

What Is Andarine S4?

Andarine S4 is a SARM (a selective androgen receptor modulator) sometimes also known as SARM S4. Like many SARMs, it has positive benefits on muscle mass, muscle gain and anabolism (helping you build muscle tissue and minimise muscle loss). But Andarine is stronger and more potent than many other SARMs.

Different SARMs have different levels of potency and this shows up in the results you can expect (and in what timeframe). What you need to know about Andarine is that it is pretty strong as SARMs go – so you can expect measurable results in a short time frame.

But there are some side effects to watch out for and we’ll detail those further in this article. However, Andarine is selective in which receptors it binds too, so side effects should be minimal if you are healthy and stick to recommended dosages.

Andarine works by binding to androgen receptors (in muscle tissue and bone tissue) which encourages your body to grow muscle. As a by-product of this, you’ll get stronger in the gym, you’ll be able to lift more and recover faster which will lead to yet more muscle gain.

Andarine S4 has been through human trials but no studies were published. There is some limited information which suggests that S-4 was described as the ideal SARM due to its single-day dosing, complete oral bioavailability and significant anabolic effects.

Understand The Benefits Of Andarine S4

Andarine can be used for bulking, cutting, body recomposition, strength gains, or competition prep but please remember you can not use Andarine – or any SARM – if you compete in drug-tested sport, including tested bodybuilding competitions because SARMs are banned by WADA.

  1. Dense muscle tissue – Andarine is renowned for giving that hard, dry look to muscles (which is why bodybuilder like it). Ideal if you want a full, pumped look
  2. Fat loss – Andarine seems to help with fat loss, possibly because it increases the metabolism of body fat and suppresses HSL (hormone-sensitive lipase)
  3. Strength gains – Andarine helps you build strength, and you may notice significant strength gains within a few weeks
  4. Dry gains – you shouldn’t experience water retention with SARM S4, meaning your muscle gains will look dry, not watery
  5. High bioavailability – meaning Andarine is absorbed into your system quickly, so it gets to work rapidly, even at low doses

You can see why S-4 is popular with bodybuilders, powerlifters, and other strength and power athletes. Just be careful with tested competition – like we’ve said, Andarine is banned (as are all SARMs) by WADA.

Are There Any Side Effects Of Andarine S4?

You should stay open to the possibility of side effects with any compound or medicine. Andarine is no different. Remember, SARMs were originally developed as potential medical solutions to physical issues, and most drugs have some potential side effects.

So what are the side effects of Andarine, and how can you minimise the chance of them happening? There are two key side effects to be aware of:

  • Night vision disturbance – some people report a kind of yellow tinge to their vision at night (probably because SARM S4 binds to receptors in the eyes). This shouldn’t be a problem – unless you work shifts, or need to drive or operate any kind of machinery at night. Most of these reports come from people taking high doses of Andarine.
  • Testosterone suppression – S4 does impact your natural test levels, and you will need to do a PCT (post cycle therapy) after using Andarine. Another way to keep this risk to a minimum is to run short cycles of 8 weeks maximum.

How To Use Andarine, Best Dosages

The best way to minimise the risks of any side effects is to get informed about how to use Andarine. This includes how much (dosages), how often (should you split the dose), and for how long (cycle length).

Andarine is a strong SARM, which means you can see good results even at low doses, so there is no need to take high doses – in fact, this just opens you up to more risk of side effects, for no need.

  • Start with 20mg-25mg Andarine a day.
  • Split your dose (whatever dose you take) into 2-3 doses per day. Take a dose in the morning, and one with your pre-training meal. If you are taking 1/3 dose, do this 4 hours after your previous dose.
  • After 2 weeks, assess your progress and results
  • If your progress has slowed down or stopped, increase the dose by 5mg per week for the rest of your cycle.
  • Do not keep increasing the dose all the while you are getting results – only increase it if your results stop.
  • Never go higher than 50mg/day (in fact, 35mg/day is a high dose).
  • Never take Andarine S4 for longer than 8 weeks (6-8 weeks is the least risky).

Andarine vs Other Popular SARMs

S4 is sometimes stacked with Ostarine (for cutting). Ostarine can be beneficial for building muscle mass and body recomposition. Andarine can also be stacked with Cardarine (for strength training), or with Ligandrol (for bulking). Remember, Andarine is already a strong SARM so there is no real need to stack.

Andarine S4 is a powerful SARM which is a kind of all-rounder, helping build muscle mass, burn body fat, and boost strength. But remember it is banned by WADA and can not be used for any tested sport or competition.

MK-677 Before and After Photos: Impressive Results

MK-677 Before and After Photos

As you might know, MK-677 is one of the most interesting compounds currently being used by athletes and bodybuilders, so we’ve pulled together a variety of MK-677 before and after photos to see just what’s realistically possible. Ibutamoren is a very potent but slow-acting compound that takes a while to kick in but when it does, results are impressive.

Perhaps you’ve read that MK-677 is a SARM, or seen it referred to as Ibutamoren or Nutrobal and you’re probably wondering exactly what this wonder-compound is (and how it can help you with your strength and physique goals). The first thing you need to know is that Ibutamoren is not a SARM. Let’s find out more about this muscle-building, fat-stripping compound so you can make an informed decision about your cutting stack.

What Exactly Is Ibutamoren MK-677?

Ibutamoren is often marketed as a SARM (selective androgen receptor modulator) but it’s actually not a SARM at all. It’s a chemical compound which can boost your body’s natural hormone levels so you can speed up muscle growth for bigger, denser muscles, more mass, greater strength, and an easier time when you next try to lean down.

MK-677 is a growth hormone secretagogue; a substance that causes growth hormone and IGF-1 to be secreted in your body. It does this by imitating ghrelin, binding to ghrelin receptors in the brain, and encouraging your natural production of GH and IGF-1. Using Ibutamoren boosts your body’s own levels of these anabolic hormones without disturbing other hormones like testosterone or cortisol. This means it is safe for long-term use and doesn’t require any form of PCT.

Ibutamoren & Bodybuilding

As mentioned, Ibutamoren boosts your body’s levels of the anabolic hormones GH (growth hormone) and IGF-1. This means it has impressive anabolic properties but without the side effects associated with actual anabolic steroids.

Ibutamoren is taken orally and can help you increase muscle mass, boost muscle size and improve your strength in training too (which will obviously also lead to better gains). It can also help you lose more body fat during a cutting diet or a body recomposition phase.

This 1998 double-blind, randomised human study shows impressive results in a group of males given Ibutamoren MK-677 – they showed increased lean mass, GH secretion, and even energy expenditure in just two months. That same study showed that serum IGF-I increased by approximately 40% with Ibutamoren MK-677 treatment.

Our MK-677 before and after photos will follow soon, keep reading…

8 Benefits of MK-677

#1 Muscle retention

Ibutamoren has been shown to reverse protein loss and associated muscle wasting – good news for bodybuilders who want to diet to lose fat but hate the idea of sacrificing hard-earned muscle mass. Muscle gain made with HGH is longer-lasting, so any gains you make on Ibutamoren are likely to last longer, too.

#2 Muscle gain

Ibutamoren MK-677 doesn’t just help you hang on to muscle mass in the face of a possibly catabolic environment. It can also boost the growth of new muscle cells. It does this by stimulating secretion of GH and IGF-1 which increase protein synthesis. That means hefty gains if you’re already eating and training right.

#3 Bone density

All that extra growth hormone will mean better bone density in the short term and the long term, which is good news for your gains now, and for your health, once you get older. Look better and stay more active in later life? Yes, please.

#4 Sleep and recovery

Ibutamoren may improve the amount of REM sleep you get (and the quality of your sleep), which means better recovery between training and more time in that muscle-gaining anabolic state. Better sleep also means more energy for training the next day, plus less hunger and fewer cravings.

#5 Nootropics

Ibutamoren is also popular with the nootropic crowd because it is thought to have brain benefits. This means better wellbeing and mood, with more motivation and focus on training and cardio.

#6 Fat loss

Using Ibutamoren may encourage your body to use stored fat for energy, and remember that it protects muscle at the same time. This means true lean gains: fat loss with muscle gain for that full, pumped, shredded look. Our MK-677 before and after photos are specifically showing the fat-loss results that people have experienced.

#7 Anti-ageing and longevity

Ibutamoren may promote longevity by increasing growth hormone and IGF-1. IGF-1 is known to have beneficial effects on ageing and longevity, however, our natural production of growth hormone declines from mid-puberty throughout life. In a study with 65 healthy adults, daily administration of MK-677 increased GH and IGF-1 levels without negative side-effects. In another study with 24 obese males, MK-677 rejuvenated the growth hormone profile.

#8 Skin tightening

Ibutamoren is known for its positive effects on the quality of hair, skin and nails. Not only does it increase fat oxidation but you’ll also notice that it will also tighten the loose skin and improve the skin quality. This is also one of the reasons why it is often used for anti-ageing, as mentioned above. In fact, many women use MK-677 to combat wrinkles and cellulite!

MK-677 Before and After Photos

These MK-677 before and after photos show cycles of different lengths. It is worth noting that this compound shows greater results if used long-term and progress will also depend on different individual factors. Your diet, training, recovery and whether you decide to stack MK-677 will greatly affect your potential. Anecdotally, people are finding very noticeable and significant effects so it’s safe to say that MK-677 is worth its weight in gold.

mk 677 before and after 02
MK-677 Before and After – 8 Week Cycle
mk 677 before and after 03
MK-677 Before and After – 12 Week Cycle
mk 677 before and after 01
MK-677 Before and After – 16 Week Cycle

If you looking for more than just MK-677 before and after photos, check out our SARMs Before and After Photos to see what else is available.

MK-677 Dosage & Stacking

Ibutamoren MK-677 can be taken by itself or as part of a stack with other compounds. It has a long half-life of 24 hours which means you can take your daily dose in one go – but it does spike growth hormone, so you might like to split your dose to avoid tiredness after the GH spike.

Most users will tend to use 20-25mg per day although MK-677 is still very effective at doses as low as 10mg, which can be useful for people who feel tired or hungry at higher doses. Start at 10mg for the first week to assess how you feel if it’s your first time using the compound.

The efficacy of MK-677 increases and improves with longer-term use, so the recommended cycle length is 3-6 months for optimum results. Some people like to stay on MK-677 year-round. Our MK-677 before and after photos show different cycle lengths but keep in mind that everyone is different and your training, diet, recovery and stacking will hugely affect results.

Recommended dosages:

  • Building muscle: 25mg per day
  • Fat loss: 20mg per day
  • Heal an injury: 10-20mg per day
  • Anti-ageing: 10-20mg per day

If you are new to Ibutamoren, start with 10mg for one week to assess your response before increasing dosages, if necessary.

Stacking MK-677 with SARMs

Ibutamoren has very minor side-effects, but it should still not be taken lightly. You still have to be careful when choosing your dose, especially if you plan on stacking it with other SARMs. And then you also have to figure out how to stack them.

But if you do choose the right dose and stack your SARMs properly, then you can expect amazing results in a short amount of time. Ibutamoren can actually enhance the effects of the SARMs that you’re currently taking.

MK-677 is often stacked with Cardarine, Ligandrol and Testolone but it is an exceptionally versatile compound and can be stacked with anything else. See our Stacks for recommendations based on your goals.

Our Best-Selling MK-677

You need to be sure the MK-677 you use is good quality, pure and well dosed. Be wary of any product which isn’t clearly labelled or can’t tell you how much of the active ingredient you are getting (we call this “micro-dosing” in the industry, and it’s bad news!).

Check out Mutagenic Labz MK-677 for a quality, reliable source of Ibutamoren Mesylate. Each capsule gives you 10mg of MK-677 so you can start small and build up your dose, or stay on a low dose for a longer period of time.

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