The Peptide IGF1-LR3, or long arginine 3-IGF-1, is a synthetic protein and lengthened analogue of human insulin-like growth factor 1 (IGF-1). This peptide differs from native IGF-1 in that it possesses an arginine instead of a glutamic acid at the third position in its amino acid sequence (“arginine 3”), and also has an additional 13 amino acids at its N-terminus (MFPAMPLLSLFVN) (“long”), for a total of 83 amino acids (relative to the 70 of IGF-1). The consequences of these modifications are that IGF-1 LR3 retains the pharmacological activity of IGF-1 as an agonist of the IGF-1 receptor, has very low affinity for the Insulin-like growth factor-binding proteins (IGFBPs), and has improved metabolic stability. As a result, it is approximately three times more potent than IGF-1 and possesses a significantly longer half-life of about 20–30 hours (relative to IGF-1’s half-life of about 12–15 hours).
Results to Expect from Peptide IGF1-LR3
IGF-1 LR3 functionality can be traced to two organs: the pancreas and the liver. Specifically, it has been determined that the peptide works with the pancreas to improve the transport of insulin secretions to cellular units throughout the body. It has also been determined to boost the secretion of IGF-1 in the liver. The highly anabolic nature of this secretion allows it to play a vital role in the growth and repair of muscular and skeletal tissue. It can elevate its effectiveness by increasing IGF-1’s half-life by a significant amount. Without the presence of the peptide, IGF-1 only lasts for around 20 minutes. However, when IGF-LR3 is added into the mix, this half-life increases dramatically to around 20 hours.
According to a scientific study that has been based on animal test subjects, the inherent functionality of IGF-LR3 has enabled it to be hypothetically linked to several elevated bodily processes. For instance, its ability to boost IGF-1’s productivity enables it to be linked to a boost in muscle repair, an elevated rate of injury recovery, and a boosted level of endurance.
Products are sold strictly for research purposes only, not for human consumption.
Storage: Lyophilized peptides although stable at room temperature for 3 months, should be stored desiccated below -18°C. Upon reconstitution of the peptide, it should be stored at 4°C between 2-21 days and for future use below -18°C.