The Mutagenic Labz MK-677 (also known as ibutamoren mesylate) is a growth hormone secretagogue. Research supports a plethora of benefits of ibutamoren, associated with its ability to increase growth hormone and IGF-1 levels naturally. A great thing about MK-677 is that it increases growth hormone levels with no increase in cortisol (cortisol suppresses the immune system, reduces wound healing, impairs learning and memory. We do recommend running MK-677 on a long-term basis, as a general staple in your supplement protocol (3-6 months minimum) to yield optimum results.
- 10mg MK-677 per capsule
- 5mg Piperine for improved absorption
- Vegan-friendly (veggie caps are used for all Mutagenic Labz products)
- Great for bulking, cutting or body recomposition
- Enhances fat loss
- Promotes healing and injury repair
- Excellent as a bridge between prohormone cycles
- Great for increasing aerobic and anaerobic endurance
- Non-toxic to the liver
- Does not require PCT
- Safe for long-term use (3-6 months recommended)
Mutagenic Labz MK-677 is Not a SARM
This is the bit most sources won’t tell you. MK-677 is not a SARM at all – the best way to describe it is as a substance that causes growth hormone and IGF-1 to be secreted. IT does this by imitating ghrelin, binding to ghrelin receptors in the brain, and encouraging the production of GH and IGF-1. Using Ibutamoren can lead to a boost in your body’s own levels of these anabolic hormones, without disturbing other hormones (like testosterone or cortisol).
How Mutagenic Labz MK-677 Works
Mutagenic Labz MK-677 promotes the secretion of the growth hormone (GH) and increases insulin-like growth factor 1 (IGF-1). It increases growth hormone levels by mimicking the action of the hormone ghrelin and binding to one of the ghrelin receptors (GHSR) in the brain. Activated GHSR stimulates growth hormone release from the brain. Results occur from as little as 5mg per day and up to 30mg per day.
Combined with the appropriate diet and exercise regimen, Ibutamoren will effectively increase muscle protein synthesis alongside much improved fat loss, as well as rapid recovery.
One human study shows impressive results in a group of males given MK-677, showing a significant increase in lean muscle mass in just two months. That same study showed that serum IGF-I increased by approximately 40% with Ibutamoren MK-677 treatment.
Benefits of MK-677
- Increased IGF-1 and growth hormone serum levels
- Increases lean muscle mass
- Increases fat oxidation
- Supports faster recovery
- Promotes healing of wounds, bones, tendons and ligaments
- Supports joint repair and health
- Increases bone density
- Tightens skin and improves skin texture
- Greatly improves sleep quality
- Ideally used long term (minimum 3-6 months) for best results
- Stacks well with any other supplements
- Superb synergistic effects when stacked with prohormones and SARMs
Side Effects of MK-677
The most common side-effects experienced with Ibutamoren include slight lethargy, some experience increased appetite, although this isn’t always a negative side-effect for those who need some help gaining weight/bulking.
MK-677 is Safe For Women
Ibutamoren is fine to use for both men and women as it doesn’t affect the amount of testosterone or estrogen the body produces. This means that there is zero-risk of specific hormonal imbalances and unwanted side-effects like puffy nipples, heightened aggression or hair loss.
How to Use MK-677
The half-life of MK-677 is 24 hours so the dosage can be taken once per day.
Ibutamoren is usually taken at 25mg per day but also works well at lower doses. Even 5-10mg is enough to produce numerous GH pulses over the course of a day.
Some users have reported more pronounced effects at higher doses of around the 25mg range but there is significant anecdotal evidence to suggest a higher dose comes with more side-effects such as lethargy and increase in appetite.
Whether you take MK-677 in the morning or before bed is down to personal preference. Some people prefer pre-bed to avoid some of the side effects such as lethargy but may disrupt sleep if the user experiences hunger pangs.
Some people find that taken first thing in the morning will improve sleep quality but may experience more lethargy during the day. These side effects are dose-dependent. Ultimately you can experiment and find what works best for you.
Stacking Mutagenic Labz MK-677
Mutagenic Labz MK-677 stacks well with anything – most commonly SARMS and prohormones. If you do choose the right dose and stack your SARMs properly, you can expect to see amazing results in a short amount of time. MK-677 enhances the effects of the SARMs that you stack with it. MK-677 is also commonly stacked with Cardarine and SR-9009 and a Glucoe Disposal Agent for rapid fat loss.