sarms vs prohormones blog

SARMs Vs Prohormones: 2 Ways to Get Big

Everything you need to compare SARMs Vs Prohormones for bodybuilding.

Prohormones and SARMs will help you to gain a significant amount of muscle and strength and, if used with quality cycle support (High Strength 1000mg TUDCA) and proper PCT, this can be achieved with little to no side effects.

Are SARMs and prohormones the same thing? What is the difference between SARMs and prohormones? What do they do, and which should you choose to reach your physique and strength goals?

People decide to take extra supplements for a number of reasons. Perhaps they’ve hit a training plateau and haven’t made progress for 6 months or more. Maybe they want a harder, denser look to their muscles. Or maybe they just want to push past what they can achieve without supplements.

Then the question turns to what kind of supplements to take? Anabolic steroids are illegal and come with some pretty hefty side effects and health risks, many of which can never be reversed. Then there are SARMs (selective androgen receptor modulators) and prohormones. Are they the same thing? What’s the difference? Which one is more effective at helping build muscle, add mass, and gain strength?

What Are SARMs?

SARMs are Selective Androgen Receptor Modulators. They work by selectively sending messages to growth cells in the body (including muscle and bone tissue), leading to rapid growth. Plus they can also help you retain lean tissue when dieting, keeping you out of the usual catabolic state so you can lose fat without also losing muscle. They can have a similar effect to anabolic steroids but without the health risks.

It is worth noting that SARMs are banned by WADA so competitive athletes should be aware that the use of SARMs is prohibited in sport.

Benefits Of SARMs

Different SARMs can have different results but the key benefits of using SARMs include:

  • Muscle gain
  • Reducing body fat (without losing muscle)
  • Increased strength
  • Faster recovery times
  • Can boost natural metabolic rate
  • Increased mood (for training focus and motivation)
  • Does not aromatise to oestrogen or DHT, or suppress natural test levels

Top 5 Most Popular SARMs

Some of the most popular SARMs are:

SARMs Side Effects

SARMs vs prohormones, the main difference is liver toxicity and suppression.

SARMs are widely accepted to be safer and free from side effects when used at lower doses and within the recommended cycle length. SARMs are non-liver-toxic and don’t require liver and organ support. You should always take SARMs as instructed (this includes doses). If you stray from the professional advice about how to take SARMs, you do open yourself up to side effects – it’s just common sense.

What Are Prohormones?

Prohormones are chemical compounds that work as precursors of a particular hormone when they are consumed, converting into that hormone within the body thanks to the interaction of enzymes. By taking prohormones, you give your body with elements it needs to create the hormones faster. Bodybuilders use prohormones which convert into anabolic (growth) hormones.

Prohormones have been around for a very long time, although many have been illegalised and no longer available on the market today. In their place, a myriad of new compounds are available and completely legal to buy.

An important note is that prohormones can show up on drug tests, suggesting anabolic steroid use so competitive athletes, government workers and military personnel would come under scrutiny from using these supplements.

Are Prohormones Safe?

The prohormones that are currently on the market are very different to the old-school compounds that are no longer available, which were much stronger and carried a lot more health risks.

The prohormones that you find on the market today can be considered quite safe, as long as you ensure to follow guidelines and use your common sense:

  • Research and understand the compounds you are planning to use
  • Use quality cycle support for liver and organ support
  • Essential: TUDCA (Liver Support) throughout your cycle
  • Essential: Pro PCT for 4 weeks after your cycle
  • Understand how to run proper PCT after your cycle
  • Don’t exceed the recommended cycle length
  • Stay within the recommended dosages
  • Do not consume any alcohol on cycle

Benefits Of Prohormones

Prohormones are highly effective and are somewhat mild compared to steroids such as Winstrol. They will guarantee quick progress. A typical cycle will usually get you at least 5-10lbs of lean muscle mass in a short space of time (3-4 weeks).

  • Highly potent muscle mass gain
  • Rapid reduction of body fat
  • Powerful increase in strength
  • Faster recovery
  • Improved nutrient partitioning
  • Muscle gain with less fat gain on a bulk
  • Increased motivation and aggression in the gym

Top 3 Most Popular Prohormones

Three of the most popular prohormones are

  • Methystenbolone – 2,17a-dimethyl-5a-androsta-1-en-17b-ol-3-one
  • Epistane – 2a, 3a epithio-17a-methyl-5a-androstan-17b-ol
  • Superdrol – 2a,17a-dimethyl-4-androstadiene-3-one,17b

Side Effects Of Prohormones

SARMs vs prohormones, the main difference is the suppression of your natural testosterone levels and liver toxicity. Prohormone use requires liver support as they are liver toxic. They should also be followed by PCT because they are suppressive. Stacking prohormones can leave you prone to more extreme side effects, including

Prohormones will help you to gain a significant amount of muscle and strength and, if used with quality cycle support (High Strength 1000mg TUDCA) and proper PCT, this can be achieved with little to no side effects such as:

  • Headaches, dizziness
  • High blood pressure
  • Hair loss
  • Acne and other skin issues
  • Water retention
  • Lowering of libido
  • Mood swings, low mood
  • Risk of gynecomastia

SARMs Vs Prohormones

SARMs Vs Prohormones are often compared when guys are looking at ways to maximise muscle gain and get more progress. So should you choose SARMs or Prohormones? Here’s the bottom line.

  • Prohormones are liver toxic, SARMs are non-liver-toxic
  • Many of the original prohormones are no longer available due to side effects
  • Prohormones carry a higher risk of side-effects
  • Prohormones are much stronger and more effective than SARMs
  • Prohormones are highly suppressive and require proper PCT
  • SARMs do not always need a PCT, depending on type, dosage and cycle length
  • There are barely any side effects with SARMs unless you run high doses
  • Neither SARMs nor prohormones are allowed in drug tested sport (regulated by WADA or any organisation that complies to the WADA banned list)
  • SARMs can be stacked with any other supplements, prohormones are limited

Check out our wide range of quality SARMs from trusted manufacturers here.

TB-500: Injury Repair and Muscle Growth

TB-500: Injury Repair and Muscle Growth (Updated 2022)

TB-500 (Thymosin Beta-4) is a potent recovery agent with a tremendous ability to enhance up injury repair and recovery, however, its many benefits also include growth of muscle mass and improved performance. TB-500 is naturally produced in the body, in higher concentration at the site of tissue damage and supports the production of new blood and muscle cells.

It also has incredibly powerful anti-inflammatory effects which can oftentimes offer instant pain relief. Its powerful healing effects have been identified specifically in the tendons, ligaments, muscle, skin, heart and eyes.

Before you read any further you should know that this peptide is banned in almost all competitive sports and events. Also, while it is readily available, Thymosin Beta-4 (also known as TB-500) is sold for research purposes only, not for human consumption.

Benefits of TB-500

  • Increases muscle growth
  • Increases endurance and stamina levels
  • Decreases inflammation in joints
  • Promotes hair growth
  • Rapid healing of wounds
  • Repair of tendons and ligaments
  • Improved flexibility of joints
  • Promotes the regeneration of blood vessels
  • Repairs damaged heart tissue following a heart attack
  • Heals ulcers and lesions (including stomach and intestinal ulcers)
  • Protects and restores neurons after brain injury

What is TB-500?

TB-500 is a synthesised peptide, essentially a short-chain version of the naturally occurring Thymosin Beta-4. It has not been used to treat humans in any tangible method but although it is not considered a veterinary-specific drug, it is often used in the treatment of horses and occasionally dogs.

As there’s little research on human trials we can only go on what we’ve heard and data compiled from various veterinary trials. Its properties are similar to those of HGH and results also appear similar.

Users report increased strength, muscle growth, enhanced recovery and relief from chronic and severe pain as well as improved endurance. There are also reports of increased hair growth, better condition hair and even a lessening of grey hair.

How does TB-500 Work?

In simple terms, TB-500 boosts your body’s protein efficiency. This means that the functions of those proteins are dramatically improved. It increases red blood cell production and improves metabolism and essentially supercharges your body’s ability to grow new cells.

Additionally, thanks to its molecular composition TB-500 is remarkably light and can, therefore, race your system finding areas to improve. It is this that makes it particularly good when it comes to targeting inflammation and pain.

How to Use TB-500

TB-500 is taken as any other peptides; you’ll need to reconstitute it before injecting the solution either subcutaneously or intramuscularly. To take SubQ, find an area of fatty tissue, the abdomen is good but avoid the navel vicinity.

Next, simply clean your hands, wipe the area with a sterile swab, pinch the area with your fingers and then inject your prepared syringe. To take intramuscularly, locate an area of muscular tissue, usually one where you are experiencing pain, and jab the syringe deep into the muscle tissue. It can be a difficult and painful process, but the rewards should outweigh the trouble.

TB-500 Dosage

The dosage depends on the purpose you are using it for, and/or the type of injury or damage that you need to treat. A general guideline would be between 4-8mg of TB-500 per week for the initial loading phase of 4 to 6 weeks, followed by 2-6mg every 2 weeks to maintain its effects. The effects wear off within 2-3 weeks of injection.

Loading phase:

      • Duration: 4-6 weeks
      • Dosage: 4-8mg of TB-500 per week
      • Frequency: 2mg per injection, between 2-4 times per week (depending on the total dosage you choose)

Maintenance phase:

    • Duration: as long as you need
    • Dosage: 2-6mg of TB-500 every 2 weeks
    • Frequency: 2mg per injection, between 2-3 times every 2 weeks (depending on the total 2-week dosage you choose)

Side Effects

The most common side-effect that has been reported by bodybuilders who use this peptide is that of lethargy and possible headaches. Some report experiencing a head rush immediately after injecting it, although this shouldn’t last longer than a minute.

We lack a lot of data on TB-500 but we do know that the medical community is divided over whether or not it has been linked to cancer; some say it increased the rate at which cancer cells grow, while others suggest it may actually promote white blood cells with which to fight it.

Combine TB-500 and BPC-157 for Healing Injury and Repair

BPC-157 and TB-500, which both stimulate wound healing via various biological mechanisms, have synergistic effects when used together. Clinically developed to boost maximum recovery as well as healing together with adjustability, joint flexibility, and also protection against injury.

BPC stands for Body Protective Compound, and that is exactly its function. It was originally discovered to be a protective peptide within our gut and to have a healing effect in both our upper and lower GI tract.

It should be understood that BPC 157 is only a small part of the whole BPC protein, but it is essential for its functionality because it is where binding spots for enzymes are located. The structure of this stable gastric pentadecapeptide consists of 15 amino acids, and looks a little something like this: Gly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val.[1]

Benefits of BPC-157

Some of the world’s top researchers around the worldare working to determine whether BPC 157 contains life-changing properties.

The list of benefits is growing by the day:

  • Useful adjunct to healing almost anything related to the GI tract
  • Heals mitochondrial damage
  • Accelerated healing of ligaments, bones, and tendons
  • Reduces inflammation in autoimmune conditions like rheumatoid arthritis,
  • Protects endothelium and the formation of scar tissue
  • Improves brain health & mood
  • Blocks long term effects of corticosteroid injections
  • Stabilized production of certain hormones and neurotransmitters (eg. serotonin)
  • Protection of the cardiovascular system
  • Reduced drug-induced damage
  • Better general body repair and wound healing
  • Improved body’s response to allergens and viruses

Researcher Ben Greenfield has written extensively about both of them, featuring them in his new book Boundless.

“I’ve personally used peptides BPC-157 and TB-500 to enhance healing and recovery.

“…BPC-157 also accelerates wound healing and, via interaction with the nitric oxide system, protects endothelial tissue and builds blood vessels”

“…TB-500 can be injected in or near any damaged muscle site and sore or injured joint with surprising healing effects”

The similarities between TB-500 and BPC-157

The main similarities between TB-500 and BPC-157 are as follows:

  • Both research peptides have demonstrated anti-inflammatory properties
  • Both research peptides promote angiogenesis (i.e. the formation of new blood vessels)
  • Some researchers contend that TB-500 and BPC-157 increase blood circulation by different mechanisms, but the end result is the same

The differences between TB-500 and BPC-157

There are some obvious differences between these two research peptides.

  • TB-500 has a systemic effect, which means it works regardless of where the injection is made
  • BPC-157 has a localized effect and must be injected near the site of the injury
  • TB-500 works to distribute actin, whereas BPC-157 is directly responsible for increasing actin production.

Keep in mind that the only way to definitively prove the difference between TB-500 and BPC-157 would be to conduct a large-scale clinical trial in which the same type of injury is being treated.

While this type of research has yet to be conducted, it is clear that BPC-157 and TB-500 do not counteract one another.

If anything, anecdotal evidence shows that they work synergistically to speed up the healing process and further accelerate the rate of recovery.

Recommended Dosage for TB-500 and BPC-157

When it comes to TB-500 vs. BPC-157, researchers should know that these research peptides have no safe or recommended dosage.

However, past studies indicate that researchers have dosed them accordingly in the past:

  • BPC-157: 250 mcg injected intramuscularly, daily – once in the morning on an empty stomach and once again right before bed
  • TB-500: 2-4 mg injected intramuscularly, twice a week in evenly spaced doses (ex. Monday and Thursday)

Cycle length is very individual and can vary depending on the specific requirements of the research subject.

Injury Repair & Recovery Stack (MK-677, BPC-157, TB-500)

The Injury Repair & Recovery Stack combines three of the best healing compounds on the market; MK-677, BPC-157 and TB-500. These compounds stimulate wound healing via various biological mechanisms and have synergistic effects when used together. Clinically developed to boost maximum recovery as well as healing together with adjustability, joint flexibility, and also protection against injury.

Pumping Iron Injury Repair & Recovery Stack
Pumping Iron Injury Repair & Recovery Stack
Best SARMs Stack for Cutting

Best SARMs Stack for Cutting (Updated 2022)

SARMs are getting increasingly more popular amongst bodybuilders, competitors and athletes, so one of the most common questions we get is to recommend the best SARMs stack for cutting. It’s not surprising when you consider that these compounds can help build muscle, give a denser, harder look to muscle and help burn body fat beyond our natural potential.

That’s the holy grail – adding mass and not losing it again when you diet! Not to mention, to speed up the process of losing body fat and revealing those chiselled abs!

Which are the best SARMs for fat loss? Here’s our take on it…

What Are SARMs & How Do They Work For Dieting?

SARMs are “selective androgen receptor modulators”, compounds which selectively bind to androgen receptors in the body’s tissues to help manipulate our natural hormone levels. Androgens are hormones which signal the body to make changes – like the way testosterone signals the body to grow.

By binding to some of the receptors which receive these hormonal messages, SARMs can specifically boost some of those signals. The key here is in the “selective” part of the name. SARMs don’t bind to every receptor (unlike anabolic hormones, which do). They only bind to receptors in bone tissue and muscle tissue. This selective nature means you get more specific in what you want the SARM to do, and you can avoid a lot of the side effects associated with steroids.

Most SARMs were initially developed as a possible way to create certain medical conditions, specifically those related to loss of bone density, muscle mass, and strength. They caught the eye of researchers because they were able to bind only to the affected tissues, and not to anything else like internal organs.

SARMs can be taken as orals which makes them easier and more user-friendly than anabolics.

But what about using SARMs for fat loss? In this article, we will look at how to use SARMs for cutting (fat loss dieting) whether you want to do that for your health, your appearance, or as a bodybuilder.

The Best SARMs for Cutting

In order to put together the best SARMs stack for cutting, we’ll take a look at the different SARMs that are best for fat loss, and the reason why they make a good choice for your dieting phase.

Each of the different compounds below has superb fat-shedding qualities and these are often interchanged depending on the preferences of the individual user. In short, the best SARMs stack for cutting is the one that works for you! See which compounds fit your preferences and do your research – that is always the best way.

Andarine S4

Andarine, or S4, is a strong and potent SARM which is thought to increase fat oxidation and reduce lipoprotein lipase which is linked to fat accumulation in the body. Initially developed to combat conditions such as osteoporosis and muscle wastage, S-4 is one of the most researched SARMs which is always a positive aspect.

Andarine also helps increase muscle mass and strength. Even low doses of Andarine can help you maintain all your gains when you go into a calorie deficit to get lean. All in all, a good choice for cutting or body recomposition.

Best dose: start at 25mg/day split into 2-3 doses (4-6 hours apart), never go higher than 50mg/day and keep cycles to an 8-12 week maximum.

Ostarine

Ostarine MK 2866 really helps boost muscle gain because it increases the body’s levels of nitrogen and protein. This makes it a good choice for protecting muscle mass when you diet, avoiding that stringy, over-dieted look.

LGD-3303 (Not LGD-4033!)

A quick update here: LGD-3303 has now been patented by pharmaceutical company Ligand Pharmaceuticals Incorporated and is no longer available on the market.

LGD-3303 is a potent and highly selective androgen receptor full agonist in skeletal muscle, a classic target tissue for androgen action. By comparison, in the prostate and sebaceous glands, the compound is a weak partial agonist. The sparing of these non-target tissues by effective, pharmacologic doses of LGD-3303 provides a novel and potentially safer treatment for osteoporosis.

Source: Ligand Pharmaceuticals Incorporated

Here’s where our recommendation on the best SARMs stack for cutting is different from any other you may have seen online. Most will recommend Ligandrol but we beg to differ. LGD-3303 is the leaner, dryer, fuller and more vascular successor of Ligandrol (LGD 4033). For that reason, it undoubtedly takes the throne.

Cardarine

Cardarine GW 501516 isn’t actually a SARM but a PPAR gamma receptor agonist that binds to PPARδ receptors instead of androgen receptors like a SARM normally would.

Cardarine supports healthy cholesterol levels and increases your basal metabolic rate, which helps your body to burn more energy (aka fat) even when at rest. You might also feel an energy boost, which definitely helps when you are dieting in a calorie deficit! Cardarine is a compound we stack with pretty much anything; this one’s a winner all-round… even when bulking to mitigate fat gain.

Stenabolic

Stenabolic SR 9009 is another on this list which isn’t actually a SARM (it’s a REV-ERB agonist) but it deserves a place on this list. As a REV-ERBα agonist, it can help manipulate certain functions relating to the metabolism, so you feel more energised, burn more stored fat, and get a boost to your metabolic rate even at rest. Stenabolic is also a compound we love to stack with pretty much anything.

MK-677

MK-677 is a growth hormone secretagogue and stacks well with virtually anything. It is a very versatile compound that can be used for both bulking or cutting, depending on the accompanying diet and training plan (increased calories will support bulking and reduced calorie intake supports fat loss).

Glucose Disposal Agents

Although Glucose Disposal Agents aren’t SARMs, they deserve a mention. Nutrient partitioning often gets forgotten about but is so effective when it comes to body composition. A glucose disposal agent decreases the amount of insulin secreted by the body when eating a high-carbohydrate meal and shuttles glucose into muscle cells instead of storing them in fat cells. This results in reduced fat gain and a potential increase in lean muscle gain.

The Best SARMs Stack for Cutting

As we’ve already pointed out, you can stack different SARMs to assist you during a cut and there are different ways to mix and match the compounds that work best for the individual.

One of the best SARMs stack for cutting we’ve researched is for the more advanced and experienced:

  • Andarine S-4 – 50mg per day, 25mg in the a.m. and 25mg 4-6 hours later
  • Ostarine MK-2866 – 20mg per day, dosed once a day in the a.m.
  • GW/SR (SR-9009/Cardarine Blend) – 1 capsule in the a.m, 1 capsule in the p.m.
  • MK-677 – 20mg per day, dosed once per day (can be reduced to 10mg if appetite increase is unmanageable).

5 Keys To Getting Shredded

Remember that there are several aspects to getting that lean, shredded look. Sure, you need to reduce your body fat. But you also want to increase muscle mass, and – crucially – retain as much muscle as possible even as you diet to lose fat. It’s a difficult task, but SARMs can make it much easier.

1 A calorie deficit

You need to be in a calorie deficit to lose body fat, it doesn’t matter what kind of diet you follow – a calorie deficit is crucial. This means making sure your total “calories out” are higher than your “calories in”

2 Sufficient protein intake

Eating enough protein will help you build muscle, maintain muscle, and it will help keep you feeling fuller (protein has the highest Thermic Effect Of Food of any macronutrient) which will help diet compliance

3 Training frequency

We now know that training frequency is the most important factor in muscle gain and muscle retention, ideally train each major muscle group every 72 hours

4 Load and volume

Within that training, you need to put enough load (weight) and volume (weight x sets x reps) through the muscles

5 Appetite and energy management

Get control of your appetite, eating habits, and your energy output to increase your success with getting super-lean and shredded!

What’s the Best PCT for SARMs?

Although PCT is a very subjective matter, it’s often recommended to run a PCT such as Pro PCT (6-OXO).

Pumping Iron Pro PCT (6-OXO) is an advanced SARMs and prohormone PCT that contains 6-OXO, a potent aromatase inhibitor which should only be used by experienced users of SARMs and prohormones. This supplement is intended for male athletes only and shouldn’t be used by women. PRO PCT can be used to prevent estrogen related side effects on-cycle as well as a powerful recovery agent for post cycle therapy (PCT)

  • Strongest aromatase inhibitor on the market
  • Increases lean muscle mass
  • Reduces conversion of testosterone to estradiol
  • Supports muscle retention
  • Increases testosterone:estrogen ratio
  • Suitable for vegans (HMPC Veg Cap)

 

sarms cycle guide dosages blog

Best SARMs Cycle Guide and Dosages (Updated 2022)

This SARMs Cycle Guide is your go-to reference for the safest and most effective research methods when it comes to selective androgen receptor modulators. If you’re unsure about the many different compounds, their half-life and recommended dosages, then you’re in the right place.

If you’ve made the decision to run a SARMs cycle to help you increase muscle mass, gain more strength and lose body fat without sacrificing muscle, then you need to know how to do it. This article will run you through exactly how to use the most popular SARMs, including their recommended dosages.

What Are SARMs?

SARMs are Selective Androgen Receptor Modulators, chemicals which work selectively on the body’s androgen receptors to help you gain muscle and strength in a targeted way, with limited side effects.

Why Use SARMs?

SARMs are thought to have similar effects to anabolic steroids and prohormones but without the risks and side effects. SARMs are non-toxic and will not impact your body’s test levels, so there is no need for PCT (post cycle therapy) and no risk of hormone-associated side effects like gynecomastia. SARMs are known to help you gain muscle mass, build strength, and lose body fat whilst retaining muscle. If you want that big, lean look with full dense muscles, SARMs can probably help you get there.

The last decade has witnessed unprecedented discovery effort to develop selective androgen receptor modulators (SARMs) that improve physical function and bone health without adversely affecting the prostate and cardiovascular outcomes. [R]

How To Take SARMs

SARMs are widely available and not associated with side effects unless you exceed the recommended dosage. That’s why you should read up on how to take SARMs so you get maximum benefits without any risks. It’s really pretty simple to achieve your goals as long as you stay within the guidelines and buy from a trusted supplier.

SARMs are available as a powder (provided in a capsule or tablet) or suspended in a liquid. All SARMs are a raw powder isolate in their original form; it is a misconception that liquid SARMs are more effective – this is simply not the case. Ultimately, whether you do your research with capsules, tablets or liquids, will come down to personal preference.

Popular SARMs Cycles & Dosages

Each SARMs cycle is different, with various types of delivery methods, as well as varying concentrations and strengths. That said, every SARMs user sticks to a dosage range. In general, most compound dosages range from 5mg to 30mg per dose. Be aware that some SARMs have more powerful effects, even at lower doses. So always start low to assess your response and increase (in 5mg) as necessary.

Ostarine MK-2866

Ostarine is one of the entry-level SARMs; it’s relatively mild and widely renowned for its overall ‘sense of wellbeing’ effects. It’s a superb healing, recovery and joint-repair compound, making it a favourite amongst athletes. MK-2866 is widely available and very popular, either as a standalone product or stacked with other SARMs.

Ostarine is known for helping you hang on to muscle mass when you are dieting to lose fat. Usually, in a calorie deficit, you would lose fat but you would also lose some lean mass (muscle). Ostarine helps to prevent catabolism so you get leaner but preserve your hard-earned muscle mass.

Ostarine is mildly suppressive on your body’s test production (suppression levels are greater if you run your SARMs cycle for longer, or use higher doses). For this reason, many people choose to use PCT after Ostarine. For short cycles of 4-8 weeks, most people will not require PCT to recover.

  • Common dosage: 10mg-25mg per day
  • Half-life: 24 hours – full dosage can be taken once per day
  • Recommended cycle length: 8-12 weeks
  • PCT? For cycles 4-8 weeks, no PCT required. For higher-dosage cycles or longer than 8 weeks, PCT is recommended

Lingadrol LGD-4033

Lingadrol is much stronger than Ostarine but has similar effects – fat loss, muscle retention and muscle gain. It can suppress natural testosterone and the HPG axis (the hypothalamus, pituitary, and gonadal glands), so pay attention to your post-cycle therapy and recovery. Use a SERM (Selective Estrogen Receptor Modulator) between cycles of Lingadrol to protect your body’s hormones.

  • Common dosage: 4-10mg per day
  • Half-life: 30 hours – full dosage can be taken once per day and LGD will build up in the system over the course of your cycle
  • Recommended cycle length: 8-12 weeks
  • PCT cycle? Yes, a full PCT including a SERM is recommended after Lingadrol

Testolone RAD-140

Testolone is one of the newer SARMs, one of the more potent compounds in the range. It is known for its ability to help you build dense muscle mass. This is a highly anabolic SARM so only use low doses. It does inhibit natural test production, so a PCT is vital. Best used during a bulk, ideally a 12-week cycle length.

  • Common dosage: 10mg-20mg per day
  • Half-life: 16-20 hours – full dosage can be taken once per day
  • Recommended cycle length: 8-12 weeks
  • PCT cycle? Yes, a full PCT including a SERM is recommended after RAD-140

Ibutamoren MK-677

MK-677, although not a SARM but often found in the same category, is also known as Nutrobal or Ibutamoren. It is a selective agonist of the growth hormone receptor, so it works by raising your body’s levels of IGF-1.

Be aware that it also mimics your appetite hormone, so your appetite is likely to increase. Great for a bulking phase (or for hard gainers who struggle to get the calories in) but maybe not so good if you have a big appetite already. Best for bulking and adding mass, as well as boosting fat loss considerably.

  • Common dosage: 10mg-25mg per day
  • Half-life: 24 hours – full dosage can be taken once per day
  • Recommended cycle length: Long-term (minimum of 4 months for best results)
  • PCT? No, MK-677 is non-hormonal and doesn’t cause any suppression, PCT is not necessary

Cardarine GW-501516

Cardarine is actually a PPAR-delta modulator (not a SARM) that works by stimulating protein receptors which help the body create muscle tissue. But so many people group it in with SARMs that we thought it best to include it here. Effects of Cardarine include muscle gain, endurance and energy.

  • Common dosage: 7mg-20mg per day
  • Half-life: 16-24 hours – full dosage can be taken once per day
  • Recommended cycle length: 8-12 weeks
  • PCT? No – Cardarine is non-hormonal and will not affect your test levels

Andarine S-4

Andarine is one of the newer SARMs. S-4 is considered to be more potent when compared to other similar SARMs such as LGD-4033. It is very effective at lower doses and can significantly increase levels of lean muscle mass while reducing body fat levels. S-4 is renowned for increasing vascularity to give the ‘chiselled’, sharp look all bodybuilders seek to achieve.

Andarine is known for building muscle mass and bone density. Stick to lower doses to avoid side effects (some unwanted side-effects such as temporary night-blindness have been reported but only at very high doses!).

  • Common dosage: 25-75mg per day
  • Half-life: 3-4 hours – dosage ideally split 3 times per day for best results
  • Recommended cycle length: 8-12 weeks
  • PCT cycle: Yes, PCT is advised

S-23

One of the most potent SARMs on the market, some say that S-23 is the closest thing to conventional steroids that you can get. An excellent cutting compound, it boosts fat loss whilst offering impressive lean, dry gains. This compound is renowned for developing a dense, hard aesthetic with no water retention. If you’re looking for grainy-looking muscles, then you should definitely consider S-23. Often stacked alongside LGD-4033 or Andarine (S-4).

  • Common dosage: 10-20mg per day
  • Half-life: 6 hours – splitting the dosage twice per day is ideal
  • Recommended cycle length: 8-12 weeks
  • PCT cycle: Yes, PCT is advised

LGD-3303

LGD-3303 is one of the newer SARMs on the market and rapidly gaining a reputation to be one of the best SARMs for overall sheer mass and strength gains. It is also known for providing a noticeable muscular fullness despite being a dry compound.

LGD-3303 offers superb oral bioavailability, is non-steroidal and binds to the androgen receptor with an extremely high affinity and selectivity. The androgenic effects in the body are minimal at the effective dosage for muscle building purposes, thus making it a very promising SARM.

LGD-3303 has also shown to stimulate aspects of female sexual behaviour and can potentially serve as a potential therapy for women with sexual desire disorders.

  • Common dosage: 10-20mg per day
  • Half-life: 12 hours – splitting the dosage twice per day is ideal
  • Recommended cycle length: 8-12 weeks
  • PCT cycle: Yes, PCT is advised

A quick update here: LGD-3303 has now been patented by pharmaceutical company Ligand Pharmaceuticals Incorporated and is no longer available on the market.

LGD-3303 is a potent and highly selective androgen receptor full agonist in skeletal muscle, a classic target tissue for androgen action. By comparison, in the prostate and sebaceous glands, the compound is a weak partial agonist. The sparing of these non-target tissues by effective, pharmacologic doses of LGD-3303 provides a novel and potentially safer treatment for osteoporosis.

Source: Ligand Pharmaceuticals Incorporated

YK-11

YK-11 appears to be a super-SARM based on the reviews, while in reality, YK-11 is not a typical SARM. It is a new synthetic steroid based on 5-α-dihydrotestosterone (DHT) which is a stronger form of testosterone that targets androgen receptors in the prostate, sex organs, hair, and liver. YK-11 has gained a lot of interest in the bodybuilding world due to its potency and ability to rapidly build muscle mass with minimal side effects.

Research has shown that YK-11 inhibits myostatin. It induces muscle cells to make more follistatin which is a strong myostatin inhibitor. Myostatin (also known as growth differentiation factor 8) is a protein produced by muscle cells which acts on muscle cells to inhibit myogenesis. Research through the years shows that when you block myostatin, it allows for significantly more muscle mass.

There is little information available on the half-life of YK11. Anecdotal experiences tell us that YK11 half-life is relatively short, meaning it should be dosed multiple times per day for optimal results.

  • Common dosage: 5-15mg per day
  • Half-life: Approximately 4-6 hours – splitting the dosage twice per day is ideal
  • Recommended cycle length: 8-12 weeks
  • PCT cycle: Yes, PCT is advised

SARMs Stacks & Dosages

SARMs are used for lots of reasons: building muscle, adding mass, increasing strength, boosting energy and mood, as well as getting leaner without losing muscle mass. What happens when you stack two or more SARMs together in the same cycle? And how should you dose a stack of SARMs? Be mindful about the combination of SARMs in a stack, the duration of your cycle and the doses. And always take a post-cycle break which is equal to the length of your cycle. With any SARMs cycle, start on the lowest dose and only increase if you need to. Lowest is always best.

Bulking SARMs Cycle

The Advanced Bulking Stack is a combination of RAD-140, LGD-4033 and Ostarine for ultimate muscle mass, strength and size gains.

RAD-140 is a dry compound (this means no water retention) paired with LGD-4033 which does carry some water resulting in higher potential for muscle protein synthesis; ultimately aiding the bulking process.

The Ostarine is renowned for its healing properties particularly joint repair and bone health. It also offers a host of other impressive benefits; it can enhance tissue regeneration, reduce inflammation and support joint health.

These compounds also work synergistically with MK-677 to amplify results.

Recommended SARMs cycle length: 12 weeks

Cutting SARMs Cycle

The Pumping Iron Cutting Stack is designed to boost your metabolism and accelerate fat loss with a combination of S-4, Cardarine and Ostarine.

A must-have if you’re looking to take your physique to the next level, whether you’re bulking, dieting or looking for body recomposition.

This stack will effectively speed up results whilst improving your overall shape, fullness, hardness and even enhances your performance (endurance, stamina, energy levels and strength).

Recommended SARMs cycle length: 12 weeks

The Best SARMs Dosages

SARMs are widely known to be effective at helping build muscle, strength, mass, and endurance whilst also helping you lose body fat. As with any drug or compound, be sensible and smart about how you use SARMs.

Always check out the recommended dose and always start low. Not only does this give you somewhere to go (if you start high, you leave yourself with nowhere to progress) but it also means you can assess the results at low doses. At lower dosages, you may be able to avoid the need for any PCT. Be smart with your SARMs cycle and see what amazing benefits you still get from SARMs.

What’s the Best PCT for SARMs?

Although PCT is a very subjective matter, it’s often recommended to run a PCT such as Pro PCT (6-OXO).

Pumping Iron Pro PCT (6-OXO) is an advanced SARMs and prohormone PCT that contains 6-OXO, a potent aromatase inhibitor which should only be used by experienced users of SARMs and prohormones. This supplement is intended for male athletes only and shouldn’t be used by women. PRO PCT can be used to prevent estrogen related side effects on-cycle as well as a powerful recovery agent for post cycle therapy (PCT)

  • Strongest aromatase inhibitor on the market
  • Increases lean muscle mass
  • Reduces conversion of testosterone to estradiol
  • Supports muscle retention
  • Increases testosterone:estrogen ratio
  • Suitable for vegans (HMPC Veg Cap)
bodybuilder steroids supplements prohormones pct guide

PCT: A Guide to Post Cycle Therapy (Updated 2022)

Post-Cycle Therapy, or PCT for short, is essentially the process of levelling your body’s hormone levels after a SARMs, steroid or prohormone cycle. Simply put, your body may cease to produce or at least lower your natural hormone production when subjected to significantly raised levels of exogenous substances.

To run the most effective PCT, there are 5 goals we want to achieve:

  1. To restart HPTA
  2. Prevent catabolism as our cortisol level rises
  3. Prevent fat gain while retaining enough calories to maintain the muscle
  4. Minimise the loss of strength
  5. To balance our hormones in order to reduce potential negative effects

HPTA Restart Protocol

Restarting the HPTA has been covered many times, a quick evolutionary search on SERMs and you will find many articles relating to the use of both Clomid and Nolvadex, these can be combined together or used solo. To restart HPTA Clomid is a solid choice but you can also use Nolvadex. Both are effective in aiding recovery.

Ostarine Prevents Catabolism During PCT

At this transition point, your body will quickly begin to produce testosterone. It’s here you must be careful not to allow excess cortisol from chewing up your hard-earned muscle. At the same time, your body will have little to no nitrogen which will cause your muscles to crave nutrients that you don’t have.

To counter these effects, prevent catabolism and lessen the amount of muscle loss, a sensible solution is to introduce a non-suppressive anabolic; and this is the greatest opportunity for SARMs to really shine. A low dose at 10mg of Ostarine (MK-2866) will help preserve your muscle gain and increase your nitrogen and IGF levels. This will also help you continue smashing your workouts and even improve muscle pumps.

Cardarine Prevents Fat Gain During PCT

After you’ve dealt with your cortisol levels, you’ll find that the excess testosterone binds with it, rendering it inactive. To prevent fat gain yet keeping your calories up requires a PPAR modulator such as Cardarine (GW-50156). This will regulate the rate at which you burn fat. It does this in a number of ways but essentially it promotes glycogen retention in muscle tissue. This allows the body to alter its metabolism and increase the amount of fat burned instead of using carbs or protein as fuel.

This is a true win/win and means your body retains muscles and yet fat retention is reduced. This, in turn, will give you more stamina and can have the added bonus of reducing cravings.

Balancing Your Hormones During PCT

The drawback to most PCT is the potentially negative side effects. To counter these you need to ensure you keep your hormones balanced. As testosterone levels rise, estrogen levels are also significantly increased and sometimes at a faster rate. Estrogen flooding causes skin problems and can even cause gynecomastia (swelling of the nipples).

To counteract this, Aromasin can be used to inhibit aromatase whilst only increasing your IGF levels by approximately 30%. Aromasin will also prevent estrogen rebound and therefore save you from developing man-boobs. Taken on alternate days, a 12.5mgs dose of Aromasin is great for PCT. It helps up your testosterone levels by actually lowering estrogen.

Benefits of an Aromatase Inhibitor

Although some supplements and SARMs do not convert to estrogen, you will still get the odd one or two guys who experience estrogen-related side effects during their cycle. In such cases, a mild over-the-counter PCT supplement with an aromatase inhibitor is ideal. Mild suppression of testosterone will throw your estrogen levels out of balance and therefore can cause side effects in those who are more prone.

The extent of these side effects will always depend on several factors:

  • Which compound you are using
  • The dose
  • The length of your cycle
  • Your individual predisposition to suppression

For most prohormones and SARMs, your best solution is Arimistane or 6-OXO.

What is 6-OXO?

6-Oxo in Pumping Iron Pro PCT is used to block the conversion of testosterone to estradiol. When the body has more testosterone, the anabolic potential is significantly increased. This will help to build more lean muscle and increase overall body strength.

By having more testosterone, not only will you have increased muscle mass but there is a greater capacity to decrease body fat. Favourable testosterone to estrogen ratio is critical for achieving optimal body composition.

Pumping Iron Pro PCT (6-OXO)
Pumping Iron Pro PCT (6-OXO)

 

  • 6-OXO is the strongest legal aromatase inhibitor on the market
  • Increases lean muscle mass
  • Reduces conversion of testosterone to estradiol
  • Supports muscle retention
  • Increases testosterone:estrogen ratio

What is Arimistane?

Arimistane is a powerful Aromatase Inhibitor (AI) and cortisol blocker that effectively reduces circulating levels of estrogen in the body. It acts as a suicide inhibitor to decrease the number of androgens in the body that can change to estrogen.

Arimistane is a great compound to use for PCT after a prohormone cycle as it increases testosterone whilst lowering estrogen levels. This also means it’s an effective natural muscle builder so you can expect a noticeable increase in muscle growth, strength, muscle hardness and definition.

Enhanced Athlete Arim-RX
Enhanced Athlete Arim-RX

 

  • Blocks high levels of estrogen and cortisol
  • Increases testosterone levels
  • Increases muscle mass
  • Reduces fat storage
  • Improves recovery
  • Improves vascularity
  • Drying and muscle hardening effect
  • Boosts libido

What is Blue Ox?

Enhanced Labs Blue Ox is a natural test booster supplement for men that supports a balanced mood and optimal strength. Blue Ox is often stacked alongside more potent PCT compounds.

Whether you’re off-cycle or just pure natty, our Blue Ox booster is chock-full of essential ingredients that excel in boosting virility and libido.

  • 120 Capsules
  • PCT Regeneration
  • Boost strength and muscle
  • Maintain muscle mass between cycles
  • Increase libido and sexual performance
  • Support healthy energy levels
  • Mood support

 

Enhanced Athlete Blue Ox Test Booster
Enhanced Athlete Blue Ox Test Booster

 

  • Clinically formulated to naturally elevate testosterone levels
  • Contains 9 naturally derived pharmaceutical grade ingredients to increase the body’s own natural testosterone production through multiple different pathways
  • Contains natural anti-estrogen ingredients to regulate estrogen production and remove the metabolites that can cause health concerns like water retention and gynecomastia
  • All of the ingredients in Blue OX have been scientifically verified in human studies

How to do a SARMs PCT

PCT protocol is a highly debated and subjective matter depending on the individual so we can’t advise you on what you should/shouldn’t do but we can give you some guidance. In general, a person cannot be sure which option is best for them unless they do blood tests before and post cycle. Every individual is different and the many factors that will affect your requirements include:

  • Your starting point/baseline
  • Any previous supplement/cycle history
  • Your predisposition/genetics
  • Your age
  • Which compound(s) you are using
  • The dosage(s)
  • The length of your cycle
  • How your body reacts to the compound(s)
  • Side effects encountered – if any

There are some options you can look at:

  1. Aromatase Inhibitor: Suitable for Ostarine and (for some people) potentially other SARMs (such as LGD-4033, LGD-3303, S-4), and/or shorter cycles up to 8 weeks): A mild over-the-counter PCT stack that includes an aromatase inhibitor (Arimistane) such as Arim-RX combined with a high-quality natural testosterone booster such as Blue Ox.
  2. SERMs: For potent compounds (such as RAD-140, YK-11, S-23), advanced stacks and long cycles: A full PCT which includes a SERM (selective estrogen receptor modulator, not to be confused with SARMs), such as Nolvadex and Clomid.
  3. 6-OXO – A very potent aromatase inhibitor that is effective for most people and most compounds including prohormones and SARMs, often combined with a natural testosterone booster such as Blue Ox.

A SERMs PCT protocol for an advanced cycle may look like:

  • Nolvadex (Weeks 1-4): 40mg/40mg/20mg/20mg
  • or Clomid (Weeks 1-4): 50mg/50mg/25mg/25mg

Preparation is key. One thing we can recommend is always having both options on hand in case you find that you need to run a full PCT, even if you haven’t anticipated this possibility.

A proper PCT is equally as important as your cycle. Don’t wait until near the end of your cycle to find the products that you need.

You can also make a judgement on the signs of testosterone suppression if you experience any of these (low energy, low libido, sadness, loss of strength and motivation, chronically poor performance in the gym) after finishing the cycle which will give you an idea of how suppressed you are. This also applies after you complete your PCT to assess the indicators of a successful PCT. Always ensure to take enough time off between cycles to ensure adequate recovery; listen to your body and if in doubt, take more time off.

Read more about Bridging Prohormone Cycles with SARMs to get the most out of your PCT protocol.

The Best Prohormones for Cutting

Best Prohormones for Cutting (Updated 2022)

The best prohormones for cutting and getting shredded are those that don’t cause water retention and provide the chiselled, well-defined physique throughout the cycle.

Getting lean and shredded is one of the most popular goals on the gym floor. Every guy wants to get super-lean at least once in his life. And when you decide to do it you’ll want to go all out. After all, there’s no point grinding through a diet and doing extra cardio if you’re only going to get mediocre results at the end of it.

If you’re planning your next cut, you might be wondering whether SARMs or prohormones could help you get that bit leaner than before…

The answer is yes, there are compounds out there that can help you burn more fat, get leaner and – crucially – hang on to muscle whilst you melt away fat.

What are the best prohormones for cutting? Let’s find out.

What Are Prohormones?

Pro hormones are different from SARMs and they are definitely not anabolic steroids either. Prohormones are really “pro-steroids”) because they act as precursors to anabolic growth hormones in your body, encouraging your body to churn out more of those muscle-building, fat burning, strength gaining hormones.

Are Prohormones Legal?

You need to do your research about the legality of prohormones (which is why you’re here!) In the USA, a lot of prohormones were banned under the 2014 Designer Anabolic Steroid Control Act of 2014 in the USA. That said, a few remain outside of this ban. These currently include:

  • 1-Androsterone (1-DHEA or 1-androstene-3b-ol-17-one)
  • 4-Androsterone (4-DHEA or 4-androstene-3b-ol-17-one)
  • 1,4-OHP
  • Epiandrosterone (Epi-Andro)
  • 6-Keto-progesterone

And do remember that all prohormones are banned by WADA, so if you are planning on doing any tested competitions – included natural or drug-free bodybuilding contest – you won’t be able to use prohormones at all.

How Do Prohormones Help You Get Leaner?

If you are thinking about using prohormones on your next cutting diet, you will want to know exactly how they would potentially help. The best prohormones for cutting and getting shredded are those that don’t cause water retention and provide the chiselled, well-defined physique throughout the entirety of the cycle.

As you know, there are a few factors that lead to some dropping body fat, retaining muscle and rocking that lean, full look.

1 Losing body fat.

The key to this is a calorie deficit, but anything that helps boost the metabolism and hang on to lean muscle will help. Prohormones can do both those things.

2 Energy output

The more energy you can burn (as long as you don’t overeat to compensate!) the more fat you’ll lose. Prohormones can give you an energy boost and training endurance.

3 Training intensity

You need to lift heavy and often to burn fat and keep muscle on in a diet. Prohormones give you the energy and drive that you need to train through a deficit.

4 Muscle retention

The more muscle tissue you can retain on a diet, the better you’ll look (and the healthier your metabolic rate will be). Prohormones can help you keep hold of more muscle.

Prohormones act as a precursor to the hormones testosterone and dihydrotestosterone, encouraging your endocrine (hormonal) system – including your pituitary and thyroid glands – to use this excess of anabolic hormones to build more muscle.

The Best Prohormones For Cutting

Here are the three most popular and effective prohormones for rapid fat loss on a cutting diet.

  1. Pumping Iron Pro DMZ is a blend of methylstenbolone and dymethazine for extreme mass and strength gains. Expect dry, hard muscle gains, fast fat loss, amazing pumps and a full lean look to your physique.For advanced users only.
  2. Pumping Iron M-Tren gives amazingly dry, lean gains in muscle mass so you can expect at increasing strength and visible physique changes, no bloat, no water retention and full muscles. Great for a body recoup or cutting cycle.
  3. Pumping Iron S-DROL is the original. The legend – extreme gains in size, power, strength, harness, vascularity and fat loss.

When you’re supplementing with prohormones, it’s important that you use the right product depending on your goals. The best prohormones for cutting are considered ‘dry’ compounds.

Prohormones fall into two main categories; wet and dry. A ‘wet’ compound will cause you to retain water during the cycle and generally be bulkier, which aids muscle protein synthesis (these prohormones are usually more potent than the dry compounds). This is great if you’re bulking but not so much if you want visible abs.

The other options are ‘dry’ compounds. These compounds will cause you to shed water and will often increase muscle hardness and fullness, as well as density and vascularity.

Stacking Prohormones

You can stack prohormones or just get the blends such as the Mutagenic Labz Mutation-X mentioned above which has done the lab work for you. Unless you are an advanced user, we don’t think it’s worth the risk of working out your own stack when you can buy a combined product that has already been created by experts.

If you’re ready to stack, we would recommend stacking Androtest and one other product.

When stacking prohormones, bear in mind that you do not need to run the products at full doses as you would if taken alone.

Prohormone Side Effects

You wouldn’t take any medication or drug without checking potential side effects, would you? So the same goes for prohormones.

Some people report increased blood pressure, acne, hair loss, liver stress, or reduced HDL cholesterol from prohormone use.

We think the best way to try and avoid any of this is by purchasing quality, trusted products (rather than trying to stack your own), always sticking to the dosage recommendations, never running a super-long cycle and always doing a PCT and natural testosterone booster afterwards to look after your health.

How To Take Prohormones For Dieting

If you buy prohormones from a trusted source, you’ll also be getting the best advice about doses and cycle length. Stick to this advice, don’t be a hero and just rely on the product to do its job.

Remember, even prohormones can’t help you lose fat if you aren’t also dieting. They’re not a magic pill (although they might feel like it!) so be sure you have your diet in check, your training is intense and regular and you stay active with a good step count or extra cardio if you have a sedentary lifestyle.

What’s The Best Cycle Support for Prohormones?

As with any pro-hormone, long term use of prohormones could have adverse effects on your liver, so you should use cycle support such as TUDCA.

The Pumping Iron TUDCA is a state of the art liver detox product that works perfectly as a detox product alone or alongside a prohormone cycle. A crucial aspect to successfully running your prohormone cycle is preserving your best health, so you can feel well in your body and revitalised after your post cycle therapy to enjoy your new-found strength and results in the long term.

What’s the Best PCT for Prohormones?

After taking pro hormones you should run a PCT such as Pro PCT (6-OXO).

Pumping Iron Pro PCT (6-OXO) is an advanced SARMs and prohormone PCT that contains 6-OXO, a potent aromatase inhibitor which should only be used by experienced users of SARMs and prohormones. This supplement is intended for male athletes only and shouldn’t be used by women. PRO PCT can be used to prevent estrogen related side effects on-cycle as well as a powerful recovery agent for post cycle therapy (PCT)

  • Strongest aromatase inhibitor on the market
  • Increases lean muscle mass
  • Reduces conversion of testosterone to estradiol
  • Supports muscle retention
  • Increases testosterone:estrogen ratio
  • Suitable for vegans (HMPC Veg Cap)
What is RAD-150 (TLB-150 Benzoate)?

What is RAD-150 (TLB-150 Benzoate)?

If you’ve researched the SARM RAD-140, then you may be wondering: what is RAD-150 (TLB-150 Benzoate)? 

RAD-150 is the latest compound gaining all the attention when it comes to research chemicals and the bodybuilding industry. With its predecessor RAD-140 taking the top spot when it comes to best-selling SARMs, everyone is wondering how RAD-150 compares and why its rapidly gaining the same level of popularity.

What is RAD-150 (TLB-150 Benzoate)?

Selective androgen receptor modulators (SARMs) are tissue-selective research drugs similar to steroids. But unlike steroids, SARMs don’t cause systematic effects. That means they only bind to muscle tissue androgen receptors and leave the rest of your body alone.

The latest SARM to hit shelves in the UK is RAD-150, also known as TLB-150 Benzoate. This research chemical is an anabolic ester. That means it better mimics the role of natural testosterone in the body as compared to non-esterized SARMs.

If you’re curious about RAD-150’s potential benefits and what sets it apart from other SARMs, keep reading for everything you need to know.

What Are Research Chemicals?

You may know that SARMs such as RAD-150 are research chemicals. What you may not know is what that actually means.

Research chemicals are compounds scientists use in pre-clinical or clinical research. For example, scientists first discovered SARMs when they were researching chemicals for prostate cancer treatment.

The thing about research chemicals is that they were originally intended for laboratory settings and not for human consumption. When you purchase SARMs from Pumping Iron, you’re consenting to the legal use of these products.

How Does RAD-150 Work?

Like all SARMs, RAD-150 binds to androgen receptors in skeletal muscle tissue. When these receptors get activated, they cause a host of downstream effects. These effects boost muscle hypertrophy, which is the same process that occurs during weight lifting.

Is RAD-150 Safe?

A 2020 study of SARM research chemicals found that many products on the market aren’t what they say they are. The researchers found that some products studied:

  • Claimed to contain active ingredients but these ingredients weren’t present in the supplements
  • Included prohibited analytes that weren’t listed on the label
  • Lacked information about the product’s safety and toxicity

This is why you should always buy research chemicals from a reputable brand. To ensure your safety, only choose SARMs from brands you can trust, like Pumping Iron.

The Benefits of RAD-150

RAD-150 provides many of the same benefits as other SARMs. For example, this research chemical can encourage lean muscle growth and reduce body fat. RAD-150 may also speed up muscle regeneration after a workout.

That’s not all, though. Some users also report increased libido and improved sexual performance after using RAD-150.

RAD-150 Side Effects

So far, the most touted side effect of RAD-150 is insomnia. This makes sense considering this research chemical has a longer half-life. Skipping days between doses or taking smaller doses may help reduce or eliminate this side effect.

The Difference Between RAD-150 and RAD-140

If you’re familiar with SARMs, you may be wondering: isn’t there a RAD-140 research chemical on the market already? RAD-140 or testolone first emerged as a safer form of Testosterone replacement therapy. It’s also a potential breast cancer tumour suppressor.

RAD-140 is the predecessor to RAD-150. They’re highly similar chemicals that look almost identical, giving them many benefits in common. For example, RAD-140 and RAD-150:

  • Enhance muscle gains
  • Boost fat loss
  • Improve strength

So, what’s the difference? As we’ve mentioned, RAD-150 is an anabolic ester. RAD-150’s structure includes an additional benzoate ester group, which offers even more benefits like the ones we’re telling you about next.

Esterized vs Non-Esterized SARMs

Esterification is the process of adding an ester group to a compound. Researchers produce esters through a chemical reaction, usually of an acid (e.g., carboxylic acid) and an alcohol. This produces a more alkaline product.

In RAD-150, the increased alkalinity makes for a more stable compound. It also makes RAD-150 more similar to natural testosterone. That means it can bind better to androgen receptors.

Because RAD-150 is an anabolic ester, it tends to act faster and last longer than other SARMs. Anabolic compounds have increased bioavailability, meaning your body absorbs them quicker. They also have a longer half-life, which allows your body to eliminate them slower.

This is why you can expect RAD-150 research chemicals to take effect rapidly and last for 48 hours or longer. Overall, RAD-150 offers way more bang for your buck than non-esterized RAD-140.

Stacking RAD-140 and RAD-150

Stacking SARMs together or alongside similar products produce synergies. Synergy refers to the fact that two chemicals together can sometimes produce more robust effects or added benefits than if those chemicals are used alone.

For example, stacking may:

  • Speed up recovery times
  • Boost fat loss
  • Enhance bulking cycles

RAD-140 and RAD-150 are ideal for stacking. Stack these SARMs with growth hormones or other bodybuilding supplements to harness these synergies and more.

Where to Buy RAD-150 (TLB0150 Benzoate)

Selective androgen receptor modulators can help you build strength and lean muscle while reducing fat content.

RAD-150 (TLB-150 Benzoate) is the latest SARM on the market. It promises even more impressive benefits. This includes a quicker onset and longer-lasting effects than any other SARM on the market.

What is Epistane Prohormone

Everything you Need to Know About Epistane (Updated 2021)

Epistane is a pro-hormone popular with bodybuilders and strength athletes especially those new to prohormone use but what is Epistane and how does it work? Epistane is an excellent prohormone for people who want fast results in increasing lean body mass, improving fitness, boosting strength and losing weight.

What is Epistane?

Epistane (2a, 3a-epithio-17a-methyl-17b-hydroxy-5a-adrostan) is a methylated derivative of Epitiostanol (Thiodrol).

The compound is a derivative of DHT and increases testosterone production. As a DHT derivative, Epistane is known to dramatically increase strength and aggression. It also produces very noticeable physique changes for the user. It’s suitable for use during cutting, recomposition or bulking cycles.

Epistane is not an injectable, it is taken orally (another benefit). It works by binding to androgen receptors across all skeletal and muscle stem cells. This sends messages from the androgen receptors to cells across the body, inducing protein synthesis and nitrogen retention.

This all results in improved strength, muscle mass and weight loss across the whole body with minimal side effects. And that, in a nutshell, is why Epistane is such a popular pro-hormone choice for bodybuilders and athletes looking for positive results quickly!

An added advantage of this product is its libido-boosting effects. If you want to enhance your sex drive and performance, you won’t be disappointed when you use this supplement.

Who Should Use Epistane?

Epistane actively causes muscle growth and fat loss. As you can imagine, this makes it a popular product for bulking and cutting cycles. So, if you are a keen athlete or bodybuilder looking for noticeable results in increased lean muscle mass or fat loss (plus increased stamina and training performance) then Epistane could be the ideal product. Epistane is often drier and has less androgenic and aromatic effects than most other pro hormones, thus it appeals to beginners or those seeking a very basic cycle.

Side note: Epistane is also an excellent prohormone if you are new to taking prohormones, although it is not limited to beginners by any means.

Adult Men Only!

Because Epistane is a derivative of DHT and increases testosterone production, it is generally advised that only males over the age of 21 should take Epistane.

What is Epistane Best For?

Epistane can deliver a range of fantastic benefits for bodybuilders and athletes, especially if you’ve already nailed a healthy diet with sufficient protein. Here are the 10 most exciting benefits of Epistane for bodybuilders.

  • Improved training performance (in weeks!)
  • Overall fat loss
  • Strength gains
  • Visible muscle mass increase across the body
  • Quicker muscle and skeletal repair (adds to training performance)
  • No bloating or water retention (like some other anabolic steroids)
  • Can help improve your general well-being
  • Promotes dry, hard muscle gains
  • Much faster post-workout recovery time
  • Very minimal side effects

How Fast Can You Expect Results with Epistane?

Various research projects have shown that Epistane has noticeable benefits within just a couple of weeks.

What is the Best Epistane Dosage?

First-time users of Epistane should use no more than 30mg daily. The dosage is split into several 10mg doses throughout the day every 6 hours due to the short half-life.

Experienced users can use up to 40mg per day, however, it’s important to understand that increased dosage will also increase the risk of potential side effects.

Some experienced users report using as much as 60mg per day, however, this is down to individual judgement and only for very advanced users.

Cycle length is usually 4 weeks but some advanced users have been known to run their cycles up to 6 weeks.

What’s The Best Cycle Support for Epistane?

As with any pro-hormone, long term use of Epistane could have adverse effects on your liver, so you should use cycle support such as TUDCA.

The Pumping Iron TUDCA is a state of the art liver detox product that works perfectly as a detox product alone or alongside a prohormone cycle. A crucial aspect to successfully running your prohormone cycle is preserving your best health, so you can feel well in your body and revitalised after your post cycle therapy to enjoy your new-found strength and results in the long term.

What’s the Best PCT for Epistane?

After taking Epistane you should run a PCT such as Pro PCT (6-OXO).

Pumping Iron Pro PCT (6-OXO) is an advanced SARMs and prohormone PCT that contains 6-OXO, a potent aromatase inhibitor which should only be used by experienced users of SARMs and prohormones. This supplement is intended for male athletes only and shouldn’t be used by women. PRO PCT can be used to prevent estrogen related side effects on-cycle as well as a powerful recovery agent for post cycle therapy (PCT)

  • Strongest aromatase inhibitor on the market
  • Increases lean muscle mass
  • Reduces conversion of testosterone to estradiol
  • Supports muscle retention
  • Increases testosterone:estrogen ratio
  • Suitable for vegans (HMPC Veg Cap)

What is Epistane Stacked With?

Epistane is often stacked with SARMs and other compounds such as MK-677 for synergistic effects. We would not recommend stacking it with other prohormones.

Epistane Overview

If you want amazing results in increasing lean muscle mass, decreasing fat levels and improving endurance, all whilst leading a healthy lifestyle and enjoying regular gym workouts, then Epistane is the product for you! It cannot convert to Estrogen or DHT, so the effects are anabolic – and you can expect results in 2-4 weeks.

Read our Guide to PCT for more information.

Laxogenin: A Natural Anabolic for Lean Muscle Gains

Laxogenin: 100% Natural Anabolic for Lean Muscle Gains

Laxogenin is a plant-derived (100% natural) supplement that offers a safe and non-liver-toxic method of gaining muscle mass as well as many all-round benefits to your health and wellbeing. Some of the notable benefits include building lean muscle, promoting fat loss, lowering cortisol levels and enhancing physical performance and recovery.

5 Alpha Hydroxy Laxogenin commonly referred to as “laxo” for short, has been shown to enhance protein synthesis by over 200%! It is structurally similar to ecdysterone, first discovered in Russia. Research has shown that Laxogenin exhibits similar anabolic properties to anabolic steroids such as Anavar; one of the most popular oral anabolic steroids of all time. However, unlike Anavar, Laxogenin exerts its effects without impacting your own body’s hormone levels meaning there is no suppression of testosterone or associated side effects seen with steroid use.

  • Build lean muscle mass
  • Promote fat loss
  • Enhance physical performance
  • Optimise recovery
  • Lowers the stress hormone cortisol (which causes fat storage and muscle breakdown)

 

Is Laxogenin Suppressive?

Laxogenin belongs to a category of plant hormones called brassinosteroids which have a similar structure to animal steroid hormones. However, plant steroids function through a completely different pathway than human steroid hormones and therefore doesn’t affect the endocrine system. It does not convert to the male sex hormones testosterone and dihydrotestosterone, nor does it convert to estrogen so you won’t need to worry about any adverse effects such as gynecomastia.

This is the highlight – this compound is completely safe for both men and women alike. The ideal supplement of choice for anyone seeking to avoid negative side effects.

Natural Muscle Building with Laxogenin

Laxogenin was first discovered in plants, from the same family that includes mustard leaves – in that form, it’s almost one of your five a day! It has some of the same properties as Anavar (or Oxandrolone), one of the most popular oral anabolic steroids of all time.

At the moment Laxogenin isn’t mainstream. That’s because most of the research that’s been done has been in the old school USSR. Word gets out though, maybe through weightlifters from back in the day – and those guys knew what they were doing.

Plant brassinosteroids and their synthetic derivatives may offer a novel therapeutic strategy for promoting growth, repair, and maintenance of skeletal muscles.

Benefits of Laxogenin

  • Accelerated recovery
  • Reduction in post-workout muscle soreness
  • Powerful anti-inflammatory effects; helps with joint pains
  • Massive pumps and vascularity
  • Faster gains in strength
  • Improved resistance to physical and mental fatigue
  • Safe for both men and women
  • 100% Natural
  • Doesn’t affect your hormones like testosterone and estrogen
  • Safe for women
  • It acts quickly and combines well with protein supplements
  • Fast-acting – ideal for anyone looking to build muscle and strength quickly
  • Can be stacked with pretty much any other compound
  • Can be used for PCT (post cycle therapy) particularly after a prohormone cycle

Supports Fat Loss

The key to what Laxogenin does isn’t totally clear, but what seems to happen is it knocks back production of cortisol, which is a stress hormone – if your cortisol levels are up you can’t grow or produce muscle. With the brakes on the cortisol, your muscles have more chance to bulk up to support your strength. One great side effect is it makes it hard to gain fat, too.

Get the Most of Your Cycle

Laxogenin can be used in many different ways to optimise results whether you’re on-cycle, off-cycle or running a PCT. Its main advantages are:

  • Stacks well with SARMs and prohormones as it doesn’t affect testosterone and estrogen
  • It’s a great alternative to prohormones if you prefer zero suppression
  • An excellent choice to add to your PCT (post cycle therapy)

Thanks to Laxogenin not messing about with your hormones, you can use it long term without hassle. We’ve seen a growing number of people use it for up to 4 months with great results building muscle, reducing body fat, boosting performance and easing mental fatigue.

Mutagenic Labz Metamorphosiz combines Laxogenin (25mg) with Epicatechin 150mg – take 2 capsules per day for best results. Take it with food for better absorption.

Are SARMs Legal?

Are SARMs Legal? (5 Olympic Athletes Banned)

Are SARMs Legal? Confused about Selective Androgen Receptor Modulators and wondering are SARMs legal in your country? We’ve got all the answers.

Are SARMs banned where I live? Can I use SARMs and compete in sport? These are some of the questions you might have if you are considering using SARMs to build muscle, lose fat, or boost your training performance.

SARMs are a relatively new type of compound, so it’s not surprising people have a lot of questions. We’ve gathered the answers together here in one essential article, so you have all the information in one place.

SARMs As Supplements

In general, SARMs are not considered illegal substances. In most countries are classed as “investigatory chemicals”. This might sound as if SARMs are therefore legal to use as sports supplements but this is where you need to be careful.

Firstly, you need to be certain of your own country’s regulations around SARMs (we will look at these in a moment). Second, you need to understand the difference between a compound being legal as an “investigatory chemical” (or research chemical) and as a food supplement or medicine.

To understand more about this distinction (and to get the current status of SARMs where you live), keep reading.

SARMs Banned In Sport

SARMs – selective androgen receptor modulators – are often used as performance-enhancing drugs by bodybuilders and other athletes. The list of effects includes strength gains, muscle mass, fat loss, endurance, and recovery.

The World Anti-Doping Agency (WADA) was founded by the International Olympic Committee to bring consistency to anti-doping rules, regulations and policies worldwide. What does WADA say about SARMs? You’ll need to know this information if you intend to compete in any drug-tested sport (including drug-tested bodybuilding federations or powerlifting competitions).

SARMS are currently prohibited by WADA, who placed them on their “prohibited at all times” list in 2008.

But what does this mean for those of you who want to use SARMs for your own training, and do not intend to compete in drug-tested sport?

Are SARMs Legal In Your Country?

Let’s look at the legal and regulatory status of SARMs (at the time of writing) in your country.

Are SARMs Legal in the UK?

The United Kingdom has no current legislation restricting SARM. It is legal to buy and sell SARMs in the UK but selling them as a food supplement or as medicine is illegal.

Are SARMs Legal in the USA?

The United States has no current legislation restricting SARMs, but this might change under the Controlled Substances Act if S. 2742 (115th): SARMs Control Act of 2018 (a bill to amend the Controlled Substances Act to more effectively regulate selective androgen receptor modulators).

Norway, Denmark, Sweden

SARMs may be seized if found by customs

Ireland

There is no current legislation to control SARMs use, but SARMs may be controlled on import.

Australia?

SARMs will likely be seized on import.

Canada

There is no current legislation to control SARMs use, but SARMs may be controlled on import.

France, Germany, Italy

There is generally no issues with import of SARMs.

Why Were SARMs Originally Developed?

SARMs were developed as medical drugs to treat various conditions, including those where muscle wasting and loss of bone density becomes a problem. The first SARMs were developed in the 1940s when researchers worked out how to modify the structure of testosterone molecules.

These early SARMs were used to treat conditions that weakened the body (by loss of muscle mass), caused a loss of strength and even organ failure. But they were considered steroidal drugs because they were derived from testosterone. Even back then, these SARM drugs had the ability to help patients rebuild muscle mass, regain strength and retain mass when they would usually have lost tissue.

In the 1990s, the current breed of SARMs began to be developed. These drugs were non-steroidal, safer than the earlier SARMs and largely without side-effects. Since then, a lot of work has been done to make SARMs more bioavailable, less toxic and generally safer.

A number of SARMs are in the clinical trial stage, but none have yet got to late-stage clinical trials (phase IV) on humans – this would give us the assessing the use of SARMs in the general public and looking at long-term effects. A lot of the big pharma and life science companies are invested in researching and developing SARMs though, so it might not be long until we see SARMs in human clinical trials.

The SARMs you can get today bind to certain receptors in certain cells, so they only impact specific areas of the body. This selective characteristic makes them powerful for muscle gain, strength gain, and retention of lean muscle tissue.

Athletes Banned For SARMs Use

Some of you competitive athletes may be wondering, are SARMs legal in sports? SARMs are banned by WADA and many sports and sporting organisations adhere to the WADA list. This includes all of the sports NGBs who make up the Association of Summer Olympic International Federations, the Commonwealth Games Federation, the IFBB for bodybuilding, and the IPF for powerlifting. You can see all the current signatories to the WADA list here.

Thomas Goller, German hurdler, was banned for 2 years in 2010 for use of Boldenone and SARMs.

Also in 2010, Bobby-Gaye Wilkins, the Jamaican sprinter, was banned from competitive athletics for 2 years after testing positive for the SARM Andarine.

Russian long jump athlete Svetlana Biryukova received a 2-year doping ban in 2014 for SARMs use.

In the same year, two-time Olympian Martin Maric (discus throw athlete for Croatia) was suspended from track and field for 2 years after testing positive for the SARM Ostarine.

Also in 2014, the race walker Irina Yumanova (Russia) was banned for 2 years for SARM use. Her coach – Viktor Chegin – was banned for life from all sport-related activities in 2016 after a number of his athletes were disqualified for doping-related offences over a period of 10 years.

Why Are SARMs Banned By WADA?

Getting back to the “prohibited at all times” status on the WADA list, why does the World Anti-Doping Agency ban SARMs for use in drug-tested sport, when they are no illegal for general use?

SARMs work! SARMs can be very effective as performance enhancers, so it stands to reason that WADA – which aims to stamp out any “unfair play” – would ban SARMs for giving an unfair advantage.

Even if you don’t need to heed WADA’s legislation, you should take a second to think about their decision over SARMs. The very fact that SARMs are banned by WADA tells us that these compounds have a definite impact on athletic performance and on other factors like muscle mass, strength, power and endurance.

SARMs should not be taken lightly. If you choose to use SARMs, always get them from a trusted, professional source, and always take them as recommended. In almost all cases, SARMs deliver amazing results even at small doses. There is no need to stray above and beyond the recommended dosage or frequency.

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