Stenabolic SR9009 - The Secret Fat Loss Wonder Drug

Stenabolic SR9009 – The Secret Fat Loss Wonder Drug (Updated 2024)

Stenabolic SR9009 is often discussed alongside SARMs, but it’s crucial to note that it is not classified as a SARM. This article aims to provide insights into Stenabolic, including its development, composition, benefits, side effects, and what users can anticipate.

Initially designed for circadian rhythm research, Stenabolic SR9009 has demonstrated significant potential to enhance the overall health and well-being of individuals. Termed ‘exercise in a bottle,’ research on Stenabolic suggests it can aid in weight loss, reduce cholesterol levels, inflammation, and even alleviate anxiety.

What Is Stenabolic SR9009?

Stenabolic SR9009 is a compound that was developed by researchers in a bid to treat or manage medical conditions.

Stenabolic is a REV-ERB (specifically a REV-ERBα agonist) which means it impacts the metabolism, including the circadian rhythm. It’s pretty complicated to explain, but here’s our best layman’s version:

Your body’s circadian rhythm is a pattern your system cycles through every 24 hours. Experts think it is linked to sunrise and sunset. It governs things like sleep, waking, energy levels, and hunger.

Part of the cycle that keeps your circadian rhythm going involves “switching” genes on and off throughout the 24-hour cycle.

History of SR-9009

Stenabolic was initially developed for its effects on the circadian rhythm and was found to improve mood, control anxiety, reduce inflammation, and even have a positive impact on weight gain. Sounds good for bodybuilding, right?

Stenabolic was also found to increase the activity of REV-ERB nuclear hormone receptors, and this boosts the bioavailability of nutrients in your body. For us as bodybuilders, this means better nutrient uptake and more of the nutrients we eat gets to our muscle tissue.

One thing you must consider about SR9009 is that there is no human research on it. There’s plenty of research from animal studies (especially mice studies) but none on human subjects.

There is plenty of anecdotal evidence and feedback from guys who use it to augment their training. So be sure to go into this with your eyes open and full awareness of the lack of human research.

How Does Stenabolic SR9009 Work?

The processes behind SR9009 are pretty complicated and well beyond a short article here. If you’re the deep-dive research kind of reader, take a look at this paper published in Nature Reviews Drug Discovery in 2014 or this 2016 paper published in the International Journal of Molecular Sciences.

SR9009 has a significant impact on REV-ERBA, which impacts circadian control and has knock-on effects on the immune system, sleeping patterns, energy production, and general activity.

Activation of Rev-ErbA-α by SR9009 increases exercise capacity by increasing mitochondria counts in skeletal muscle.

REV-ERB is particularly influential in the tissues of the muscles, body fat, and liver. This suggests it could help boost fat burning, “switching off” the genes which store fat and increasing the number of mitochondria in the muscles.

OK, that’s a lot of scientific talk (and a couple of papers for you to look at). But what about the real-life stuff – how does SR 9009 benefit bodybuilders and people who want to get big, ripped, and lean?

Benefits of Stenabolic SR9009

Stenabolic SR9009 has been shown to have several potential benefits, including increased endurance and stamina, improved metabolism and fat burning, and enhanced recovery after exercise.

It may also have neuroprotective and anti-inflammatory effects.

  • Increases oxygen consumption
  • Prevents the creation of new fat cells in the liver
  • Increases the number of mitochondria in the muscle cells
  • Increases glucose and lipid metabolism
  • Decreases triglyceride levels in the blood
  • Reduces cholesterol breakdown in the liver
  • Promotes fat loss through glucose consumption
  • Regulates blood sugar levels
  • SR9009 has even been used to treat type-2 Diabetes
  • Delays the ageing process
  • Reduces inflammation
  • Decreases anxiety

1 Weight loss & fat loss

SR9009 has been shown to increase weight loss even without altering dietary intake. It has also been shown to reduce amounts of free fatty acids, triglycerides, and cholesterol. It could be great as a fat burner when you’re dieting or trying to get rid of that last bit of body fat.

2 Mood & energy

SR9009 is thought to be able to affect sleep patterns, which is beneficial to recovery and general health. It has been shown to increase energy levels and could even be used to increase wakefulness. Some studies also suggest SR 9009 could reduce anxiety.

3 Endurance

SR9009 has been shown to increase the total amount of mitochondria, which has a direct impact on endurance levels for physical activity. More endurance = more training = more gains.

4 Reduced inflammation

Inflammation can pose a big problem for bodybuilders who train hard, and Stenabolic SR9009 may be able to tackle this issue (by reducing TNF alpha in the body – these cells are a key player in systemic inflammation).

Does Stenabolic Have Side Effects?

Since Stenabolic SR9009 is a research chemical and has not been extensively studied in humans, the potential side effects are not fully known. However, some users have reported side effects such as headache, nausea, and insomnia.

Stenabolic has shown no liver toxicity.

However, we do know that SR9009 doesn’t impact the body’s natural hormone levels so you won’t need to run a PCT if you use Stenabolic.

Is Stenabolic SR9009 legal?

Stenabolic SR9009 is not approved for human consumption, however it is legal to sell and purchase for research purposes.

Is Stenabolic SR9009 a Steroid?

Stenabolic SR9009 is not a steroid, but it is often grouped together with other performance-enhancing compounds due to its potential benefits for athletes and bodybuilders. It is important to note that using any performance-enhancing compound comes with potential risks and side effects.

Best Dosage & Cycle Length for Stenabolic

Stenabolic has a half-life of 4 hours so you’ll need to split your total daily dose into 2-3 doses per day. So, if you’re taking 20mg/day, take 5mg every 4 hours (say, at 8 am, 12 pm, 4 pm, 8 pm).

Start at 10mg-20mg/day (maximum) and increase only to 30mg if you need to.

Most will run Stenabolic SR9009 cycles of 8-12 weeks, followed by the same time off.

How to Use Stenabolic SR9009

Stenabolic SR9009 is typically taken orally in capsule form. The recommended dosage is usually between 20-30mg per day, although dosages may vary depending on individual needs and goals.

Can Stenabolic SR9009 be Stacked with other Supplements

Stenabolic SR9009 can be stacked with other supplements or compounds, but it is important to do so carefully and with the guidance of a healthcare professional. Some users have reported success in stacking SR9009 with other SARMs or compounds such as Cardarine, Ostarine, and Ligandrol.

Does SR-9009 Require a PCT?

Stenabolic (SR-9009) is not suppressive and does not generally require a PCT.

Glucose Disposal Agents: Hidden Secret to Fat Loss (2024)

Glucose Disposal Agents: Hidden Secret to Fat Loss (2024)

Glucose disposal agents (GDAs) are designed to help the body handle and use glucose more efficiently. They are becoming increasingly popular among fitness enthusiasts and those looking to lose fat and improve insulin sensitivity. In this article, we will explore the benefits of using glucose disposal agents for fat loss and improved insulin resistance.

What are Glucose Disposal Agents?

Glucose Disposal Agents (GDAs) are compounds or supplements designed to improve the body’s ability to handle glucose and regulate blood sugar levels. They work by enhancing the uptake of glucose by muscle cells, increasing insulin sensitivity, and promoting glycogen synthesis. This can lead to improved nutrient partitioning, where carbohydrates are more efficiently directed towards muscle cells for energy rather than being stored as fat.

What is Insulin Resistance?

First, let’s talk about insulin resistance. Insulin is a hormone that helps the body use and store glucose, which is the body’s primary source of energy. When the body becomes resistant to insulin, it can lead to a host of health problems, including weight gain, diabetes, and heart disease. Insulin resistance can occur when the body is exposed to high levels of glucose for prolonged periods of time, such as when consuming a diet high in refined carbohydrates.

Glucose Disposal Agents improve Insulin Sensitivity

Glucose Disposal Agents can help improve insulin sensitivity by increasing the body’s ability to use and store glucose. They do this by increasing the number of glucose transporters (GLUTs) in the cells, which are responsible for moving glucose into the cells. By increasing the number of GLUTs, GDAs help the body use glucose more efficiently and reduce the amount of glucose that is stored as fat.

How Glucose Disposal Agents can Aid Fat Loss

In addition to improving insulin sensitivity, Glucose Disposal Agents can also aid in fat loss. When the body is able to use glucose more efficiently, it is less likely to store it as fat. Furthermore, GDAs can also help reduce cravings for sugary foods, which can lead to overeating and weight gain.

Improve Endurance and Increase Muscle Mass with Glucose Disposal Agents

Another benefit of Glucose Disposal Agents is that they can help improve muscle mass and athletic performance. When the body is able to use glucose more efficiently, it can use it as a fuel source during exercise, rather than relying on stored fat. This can lead to improved endurance and increased muscle mass.

What is the Best GDA?

There are several different types of Glucose Disposal Agents available on the market, including berberine, alpha-lipoic acid, and cinnamon extract. Each of these supplements has been shown to improve insulin sensitivity and aid in fat loss. However, it is important to consult with a healthcare professional before starting any supplement regimen, as some GDAs can interact with certain medications and may not be suitable for certain individuals.

Ingredients to Look for in Glucose Disposal Agents


Chromium is an essential mineral that may play a key role in glucose metabolism, weight loss and blood sugar control. Supplementing with its form called chromium picolinate has been demonstrated to lead to beneficial reductions in body fat and overall weight among some study participants.

Garcinia Cambogia

Garcinia Cambogia, a fruit found in tropical climates worldwide, has gained recent attention as an effective weight loss supplement. Its active ingredient – hydroxycitric acid (HCA) – is thought to aid shedding excess pounds by blocking the production of fat and suppressing hunger pangs. With dozens of studies backing its efficacy, this natural dietary product could be your key to success!

Glucomannan (from Konjac Root)

Glucomannan is a type of dietary fiber that comes from the root of the konjac plant. It is believed to help with weight loss by promoting feelings of fullness and reducing overall calorie intake. Glucomannan, being a water-soluble fiber, can help to slow down the digestion process, which may lead to a more gradual rise in blood sugar levels, which in turn can help to improve insulin sensitivity.

Bitter Melon Extract

Bitter Melon (Momordica charantia) has been used for centuries to promote wellness in various cultures around the world. Recent studies suggest that certain components found within the extract, such as charantin, momordin and polypeptide-p, could contribute to a healthier weight by suppressing appetite and reducing fat accumulation while promoting glucose uptake into individual cells. It is clear why this vegetable remains so popular!

Berbenne Hydrochloride

Berberine Hydrochloride is an alkaloid found in several plants, It is commonly used as an herbal supplement that has various benefits, such as to lower blood sugar, cholesterol, and blood pressure, to improve gut health, and to support the immune system.

Cinnamon Bark Extract

Cinnamon Bark Extract is an increasingly popular supplement, derived from the bark of cinnamon trees. It contains cinnamaldehyde – which gives it its unique taste and smell – as well as being studied for potential health benefits such as helping in weight loss and glucose metabolism related to insulin sensitivity.

White Kidney Bean Extract

White Kidney Bean Extract is a type of carbohydrate blocker that is thought to help with weight loss by inhibiting the enzyme alpha-amylase, which is responsible for breaking down carbohydrates into sugar. By inhibiting the enzyme, White Kidney Bean Extract may reduce the absorption of carbohydrates, and  improve insulin sensitivity and glucose metabolism.

Alpha Lipoic Acid

Alpha Lipoic Acid (ALA) is an antioxidant found in small amounts in certain foods. Supplementing with Alpha Lipoic Acid (ALA) may be an effective way to reduce both body weight and fat, according to research. A study published in the International Journal of Medical Sciences observed a statistically significant decrease in individuals’ body weight and fat when taking ALA supplements; additionally, it found that insulin sensitivity was improved as well as glucose metabolism.

Fenugreek Extract

Fenugreek, or Trigonella foenum-graecum, has a long history of traditional use for its medicinal properties. This herb is commonly consumed in supplement form with potential efficacy seen in aiding weight loss and moderating blood sugar levels as well as boosting insulin sensitivity. The active compounds found within the extract are believed to help reduce food cravings while slowing down carbohydrate digestion – both processes that can lead to reduced calorie intake and improved metabolism.


Myricetin is a natural compound found in plant-based foods with incredible potential. This powerful flavonoid contains potent antioxidant properties and has been studied for its positive influence on weight loss and insulin sensitivity in metabolic disease sufferers. Research indicates Myricetin can inhibit the formation of new fat cells, while also normalizing blood sugar levels by improving overall insulin sensitivity within the body – making it an essential player against obesity & diabetes!

Banaba Powder

Banaba powder, native to Southeast Asia, is quickly becoming a popular dietary supplement with potential health benefits. Rich in corosolic acid – a triterpenoid compound – Banaba has been linked to improved weight loss and insulin sensitivity when used as part of an overall healthy lifestyle. With the additional support from studies to back its promise up, this powerful plant may just be your key missing link for healthier living!

African Mango Extract

African Mango Extract is an exciting dietary supplement derived from the seeds of African Mangoes, a tree native to West Africa. High in fiber and healthy fats with potential benefits including weight loss and improved insulin sensitivity, this natural extract has been gaining attention for its significant health implications – recent studies have shown that it could aid individuals trying to reduce body fat or increase their insulin sensitivity.

The SLIN Glucose Disposal Agent

Enhanced Labs Slin is a potent glucose disposal agent (GDA) designed to help partition carbohydrate absorption in the body. A Glucose Disposal Agent (GDA) and is essential for anyone who wants to enhance nutrient partitioning and stabilising blood glucose levels. Ultimately, this greatly improves your ability to gain lean muscle mass and reduce body fat levels.

  • 120 Capsules
  • Powerful carb blocker
  • Insulin mimetic
  • Minimises fat storage
  • Supports muscle growth
  • Helps to optimise blood glucose levels
  • Shuttles carbs into muscle cells
  • Perfect for carb-up before a competition
  • Promotes insane muscle fullness, crazy pumps and vascularity like never before
  • Helps build quality muscle mass that won’t disappear after use
  • Increases endurance levels
  • A must-have for any athlete or bodybuilder
Enhanced Labs SLIN (120 Capsules)
Enhanced Labs SLIN (120 Capsules)


In conclusion, glucose disposal agents are supplements that can help improve insulin sensitivity and aid in fat loss. By increasing the number of glucose transporters in the cells, GDAs help the body use glucose more efficiently and reduce the amount of glucose that is stored as fat. They can also help reduce cravings for sugary foods, improve muscle mass and athletic performance. However, it is important to consult with a healthcare professional before starting any supplement regimen.

The Best Prohormones for Cutting

Best Prohormones for Cutting (Updated 2024)

The best prohormones for cutting and getting shredded are those that don’t cause water retention and provide the chiselled, well-defined physique throughout the cycle.

Getting lean and shredded is one of the most popular goals on the gym floor. Every guy wants to get super-lean at least once in his life. And when you decide to do it you’ll want to go all out. After all, there’s no point grinding through a diet and doing extra cardio if you’re only going to get mediocre results at the end of it.

If you’re planning your next cut, you might be wondering whether SARMs or prohormones could help you get that bit leaner than before…

The answer is yes, there are compounds out there that can help you burn more fat, get leaner and – crucially – hang on to muscle whilst you melt away fat.

What are the best prohormones for cutting? Let’s find out.

What Are Prohormones?

Pro hormones are different from SARMs and they are definitely not anabolic steroids either. Prohormones are really “pro-steroids”) because they act as precursors to anabolic growth hormones in your body, encouraging your body to churn out more of those muscle-building, fat burning, strength gaining hormones.

Are Prohormones Legal?

You need to do your research about the legality of prohormones (which is why you’re here!) In the USA, a lot of prohormones were banned under the 2014 Designer Anabolic Steroid Control Act of 2014 in the USA. That said, a few remain outside of this ban. These currently include:

  • 1-Androsterone (1-DHEA or 1-androstene-3b-ol-17-one)
  • 4-Androsterone (4-DHEA or 4-androstene-3b-ol-17-one)
  • 1,4-OHP
  • Epiandrosterone (Epi-Andro)
  • 6-Keto-progesterone

And do remember that all prohormones are banned by WADA, so if you are planning on doing any tested competitions – included natural or drug-free bodybuilding contest – you won’t be able to use prohormones at all.

How Do Prohormones Help You Get Leaner?

If you are thinking about using prohormones on your next cutting diet, you will want to know exactly how they would potentially help. The best prohormones for cutting and getting shredded are those that don’t cause water retention and provide the chiselled, well-defined physique throughout the entirety of the cycle.

As you know, there are a few factors that lead to some dropping body fat, retaining muscle and rocking that lean, full look.

1 Losing body fat.

The key to this is a calorie deficit, but anything that helps boost the metabolism and hang on to lean muscle will help. The best prohormones for cutting can do both those things.

2 Energy output

The more energy you can burn (as long as you don’t overeat to compensate!) the more fat you’ll lose. Prohormones can give you an energy boost and training endurance.

3 Training intensity

You need to lift heavy and often to burn fat and keep muscle on in a diet. Prohormones give you the energy and drive that you need to train through a deficit.

4 Muscle retention

The more muscle tissue you can retain on a diet, the better you’ll look (and the healthier your metabolic rate will be). Prohormones can help you keep hold of more muscle.

Prohormones act as a precursor to the hormones testosterone and dihydrotestosterone, encouraging your endocrine (hormonal) system – including your pituitary and thyroid glands – to use this excess of anabolic hormones to build more muscle.

The Best Prohormones For Cutting

Here are the three best prohormones for cutting, producing lean/dry gains with no water retention:

  1. Pumping Iron Pro DMZ is a blend of methylstenbolone and dymethazine for extreme mass and strength gains. Expect dry, hard muscle gains, fast fat loss, amazing pumps and a full lean look to your physique.For advanced users only.
  2. Pumping Iron M-Tren gives amazingly dry, lean gains in muscle mass so you can expect at increasing strength and visible physique changes, no bloat, no water retention and full muscles. Great for a body recoup or cutting cycle.
  3. Pumping Iron S-DROL is the original. The legend – extreme gains in size, power, strength, harness, vascularity and fat loss.

When you’re supplementing with prohormones, it’s important that you use the right product depending on your goals. The best prohormones for cutting are considered ‘dry’ compounds.

Prohormones fall into two main categories; wet and dry. A ‘wet’ compound will cause you to retain water during the cycle and generally be bulkier, which aids muscle protein synthesis (these prohormones are usually more potent than the dry compounds). This is great if you’re bulking but not so much if you want visible abs.

The other options are ‘dry’ compounds. These compounds will cause you to shed water and will often increase muscle hardness and fullness, as well as density and vascularity.

Stacking Prohormones

You can stack prohormones or just get the blends such as the Pro-DMZ mentioned above which has done the lab work for you. Unless you are an advanced user, we don’t think it’s worth the risk of working out your own stack when you can buy a combined product that has already been created by experts.

When stacking prohormones, bear in mind that you do not need to run the products at full doses as you would if taken alone.

Prohormone Side Effects

Some people report increased blood pressure, acne, hair loss, liver stress, or reduced HDL cholesterol from prohormone use.

We think the best way to try and avoid any of this is by purchasing quality, trusted products (rather than trying to stack your own), always sticking to the dosage recommendations, never running a super-long cycle and always doing a PCT and natural testosterone booster afterwards to look after your health.

How To Take Prohormones For Dieting

If you buy prohormones from a trusted source, you’ll also be getting the best advice about doses and cycle length. Stick to this advice, don’t be a hero and just rely on the product to do its job.

Remember, even the best prohormones for cutting can’t help you lose fat if you aren’t also dieting. They’re not a magic pill (although they might feel like it!) so be sure you have your diet in check, your training is intense and regular and you stay active with a good step count or extra cardio if you have a sedentary lifestyle.

What’s The Best Cycle Support for Prohormones?

As with any pro-hormone, long term use of prohormones could have adverse effects on your liver, so you should use cycle support such as Pumping Iron High Strength TUDCA.

Pumping Iron TUDCA 1000mg (High Strength Liver Detox)
Pumping Iron TUDCA 1000mg (High Strength Liver Detox)


The Pumping Iron TUDCA is a state of the art liver detox product that works perfectly as a detox product alone or alongside a prohormone cycle. A crucial aspect to successfully running your prohormone cycle is preserving your best health, so you can feel well in your body and revitalised after your post cycle therapy to enjoy your new-found strength and results in the long term.

What’s the Best PCT for Prohormones?

After taking pro hormones you should run a PCT such as Pro PCT (6-OXO).

Pumping Iron Pro PCT (6-OXO) is an advanced SARMs and prohormone PCT that contains 6-OXO, a potent aromatase inhibitor which should only be used by experienced users of SARMs and prohormones. This supplement is intended for male athletes only and shouldn’t be used by women. PRO PCT can be used to prevent estrogen related side effects on-cycle as well as a powerful recovery agent for post cycle therapy (PCT).

  • Strongest aromatase inhibitor on the market
  • Increases lean muscle mass
  • Reduces conversion of testosterone to estradiol
  • Supports muscle retention
  • Increases testosterone:estrogen ratio
  • Suitable for vegans (HMPC Veg Cap)
Pumping Iron Pro PCT (6-OXO)
Pumping Iron Pro PCT (6-OXO)
Best SARMs Stack for Cutting

Best SARMs Stack for Cutting (Ultimate Guide 2024)

SARMs are getting increasingly more popular amongst bodybuilders, competitors and athletes, so one of the most common questions we get is to recommend the best SARMs stack for cutting. It’s not surprising when you consider that these compounds can help build muscle, give a denser, harder look to muscle and help burn body fat beyond our natural potential.

That’s the holy grail – adding mass and not losing it again when you diet! Not to mention, to speed up the process of losing body fat and revealing those chiselled abs!

Which are the best SARMs for fat loss? Here’s our take on it…

What Are SARMs & How Do They Work For Dieting?

SARMs are “selective androgen receptor modulators”, compounds which selectively bind to androgen receptors in the body’s tissues to help manipulate our natural hormone levels. Androgens are hormones which signal the body to make changes – like the way testosterone signals the body to grow.

By binding to some of the receptors which receive these hormonal messages, SARMs can specifically boost some of those signals. The key here is in the “selective” part of the name. SARMs don’t bind to every receptor (unlike anabolic hormones, which do). They only bind to receptors in bone tissue and muscle tissue. This selective nature means you get more specific in what you want the SARM to do, and you can avoid a lot of the side effects associated with steroids.

Most SARMs were initially developed as a possible way to create certain medical conditions, specifically those related to loss of bone density, muscle mass, and strength. They caught the eye of researchers because they were able to bind only to the affected tissues, and not to anything else like internal organs.

SARMs can be taken as orals which makes them easier and more user-friendly than anabolics.

But what about using SARMs for fat loss? In this article, we will look at how to use SARMs for cutting (fat loss dieting) whether you want to do that for your health, your appearance, or as a bodybuilder.

The Best SARMs for Cutting

In order to put together the best SARMs stack for cutting, we’ll take a look at the different SARMs that are best for fat loss, and the reason why they make a good choice for your dieting phase.

Each of the different compounds below has superb fat-shedding qualities and these are often interchanged depending on the preferences of the individual user. In short, the best SARMs stack for cutting is the one that works for you! See which compounds fit your preferences and do your research – that is always the best way.

Andarine S4

Andarine, or S4, is a strong and potent SARM which is thought to increase fat oxidation and reduce lipoprotein lipase which is linked to fat accumulation in the body. Initially developed to combat conditions such as osteoporosis and muscle wastage, S-4 is one of the most researched SARMs which is always a positive aspect.

Andarine also helps increase muscle mass and strength. Even low doses of Andarine can help you maintain all your gains when you go into a calorie deficit to get lean. All in all, a good choice for cutting or body recomposition.

Best dose: start at 25mg/day split into 2-3 doses (4-6 hours apart), never go higher than 50mg/day and keep cycles to an 8-12 week maximum.


Ostarine MK 2866 really helps boost muscle gain because it increases the body’s levels of nitrogen and protein. This makes it a good choice for protecting muscle mass when you diet, avoiding that stringy, over-dieted look.

LGD-3303 (Not LGD-4033!)

A quick update here: LGD-3303 has now been patented by pharmaceutical company Ligand Pharmaceuticals Incorporated and is no longer available on the market.

LGD-3303 is a potent and highly selective androgen receptor full agonist in skeletal muscle, a classic target tissue for androgen action. By comparison, in the prostate and sebaceous glands, the compound is a weak partial agonist. The sparing of these non-target tissues by effective, pharmacologic doses of LGD-3303 provides a novel and potentially safer treatment for osteoporosis.

Source: Ligand Pharmaceuticals Incorporated

Here’s where our recommendation on the best SARMs stack for cutting is different from any other you may have seen online. Most will recommend Ligandrol but we beg to differ. LGD-3303 is the leaner, dryer, fuller and more vascular successor of Ligandrol (LGD 4033). For that reason, it undoubtedly takes the throne.


Cardarine GW 501516 isn’t actually a SARM but a PPAR gamma receptor agonist that binds to PPARδ receptors instead of androgen receptors like a SARM normally would.

Cardarine supports healthy cholesterol levels and increases your basal metabolic rate, which helps your body to burn more energy (aka fat) even when at rest. You might also feel an energy boost, which definitely helps when you are dieting in a calorie deficit! Cardarine is a compound we stack with pretty much anything; this one’s a winner all-round… even when bulking to mitigate fat gain.


Stenabolic SR 9009 is another on this list which isn’t actually a SARM (it’s a REV-ERB agonist) but it deserves a place on this list. As a REV-ERBα agonist, it can help manipulate certain functions relating to the metabolism, so you feel more energised, burn more stored fat, and get a boost to your metabolic rate even at rest. Stenabolic is also a compound we love to stack with pretty much anything.


MK-677 is a growth hormone secretagogue and stacks well with virtually anything. It is a very versatile compound that can be used for both bulking or cutting, depending on the accompanying diet and training plan (increased calories will support bulking and reduced calorie intake supports fat loss).

Glucose Disposal Agents

Although Glucose Disposal Agents aren’t SARMs, they deserve a mention. Nutrient partitioning often gets forgotten about but is so effective when it comes to body composition. A glucose disposal agent decreases the amount of insulin secreted by the body when eating a high-carbohydrate meal and shuttles glucose into muscle cells instead of storing them in fat cells. This results in reduced fat gain and a potential increase in lean muscle gain.

The Best SARMs Stack for Cutting

As we’ve already pointed out, you can stack different SARMs to assist you during a cut and there are different ways to mix and match the compounds that work best for the individual.

One of the best SARMs stack for cutting we’ve researched is for the more advanced and experienced:

  • Andarine S-4 – 50mg per day, 25mg in the a.m. and 25mg 4-6 hours later
  • Ostarine MK-2866 – 20mg per day, dosed once a day in the a.m.
  • GW/SR (SR-9009/Cardarine Blend) – 1 capsule in the a.m, 1 capsule in the p.m.
  • MK-677 – 20mg per day, dosed once per day (can be reduced to 10mg if appetite increase is unmanageable).

5 Keys To Getting Shredded

Remember that there are several aspects to getting that lean, shredded look. Sure, you need to reduce your body fat. But you also want to increase muscle mass, and – crucially – retain as much muscle as possible even as you diet to lose fat. It’s a difficult task, but SARMs can make it much easier.

1 A calorie deficit

You need to be in a calorie deficit to lose body fat, it doesn’t matter what kind of diet you follow – a calorie deficit is crucial. This means making sure your total “calories out” are higher than your “calories in”

2 Sufficient protein intake

Eating enough protein will help you build muscle, maintain muscle, and it will help keep you feeling fuller (protein has the highest Thermic Effect Of Food of any macronutrient) which will help diet compliance

3 Training frequency

We now know that training frequency is the most important factor in muscle gain and muscle retention, ideally train each major muscle group every 72 hours

4 Load and volume

Within that training, you need to put enough load (weight) and volume (weight x sets x reps) through the muscles

5 Appetite and energy management

Get control of your appetite, eating habits, and your energy output to increase your success with getting super-lean and shredded!

What’s the Best PCT for SARMs?

Although PCT is a very subjective matter, it’s often recommended to run a PCT such as Pro PCT (6-OXO).

Pumping Iron Pro PCT (6-OXO)
Pumping Iron Pro PCT (6-OXO)


Pumping Iron Pro PCT (6-OXO) is an innovative, advanced solution for male athletes who use SARMs and prohormones. Formulated with a potent aromatase inhibitor – 6-OXO – this supplement can be used as both preventative care against estrogen related side effects while cycling or during post cycle therapy to aid in recovery.

  • Strongest aromatase inhibitor on the market
  • Increases lean muscle mass
  • Reduces conversion of testosterone to estradiol
  • Supports muscle retention
  • Increases testosterone:estrogen ratio
  • Suitable for vegans (HMPC Veg Cap)


Best Time to Take MK677: Morning vs Night Time

Best Time to Take MK677: Morning vs Night Time

The best time to take MK677 has become a point of interest for those seeking to maximize the benefits of this compound. Also known as Ibutamoren, MK677 has garnered significant attention for its potential to stimulate growth hormone levels and promote muscle growth and fat loss.

Yet, amid varying opinions and conflicting advice, the timing of MK677 administration remains a highly debated subject. In this article, we delve deep into the complexities surrounding the optimal dosing schedule of MK677, examining scientific insights and practical considerations to uncover its potential impact on effectiveness.

What is MK677, and how does it work?

MK677, also known as Ibutamoren, is a growth hormone secretagogue; a substance that stimulates the release of growth hormone from the pituitary gland and insulin-like growth factor 1 (IGF-1).

Despite being commonly referred to as a SARM, it doesn’t bind to androgen receptors like traditional SARMs. Instead, MK677 acts as a potent ghrelin receptor agonist, targeting the ghrelin receptor (GHSR) in the brain.

This case study shows effects of MK677 on body composition in healthy older adults:

To determine whether MK-677, an oral ghrelin mimetic, increases growth hormone secretion into the young-adult range without serious adverse effects, prevents the decline of fat-free mass, and decreases abdominal visceral fat in healthy older adults.

Conclusion: Over 12 months, the ghrelin mimetic MK-677 enhanced pulsatile growth hormone secretion, significantly increased fat-free mass, and was generally well tolerated.

Scientific Background:

Ghrelin is a hormone produced in the stomach and plays a crucial role in stimulating appetite and promoting growth hormone release from the pituitary gland. MK677 functions by mimicking the action of ghrelin, binding to and activating the ghrelin receptor in the hypothalamus. This activation leads to increased signaling in the growth hormone-releasing hormone (GHRH) neurons and subsequently the release of growth hormone from the pituitary gland.

Real-Life Applications:

  1. Increasing Growth Hormone Levels: MK677 is used to enhance growth hormone levels in individuals with growth hormone deficiency, and it can be beneficial for promoting growth in children with growth disorders.
  2. Muscle Mass and Strength: The elevation of growth hormone and IGF-1 levels by MK677 can help improve muscle mass, strength, and recovery in athletes and bodybuilders.
  3. Bone Density: MK677 may have potential benefits for increasing bone mineral density and bone health in certain individuals, especially the elderly and those with osteoporosis.
  4. Anti-Aging Effects: Some research suggests that increasing growth hormone levels with MK677 might have anti-aging effects, although more studies are needed to establish its long-term safety and efficacy in this context.
  5. Appetite Stimulation and Cachexia: MK677 has shown promise in stimulating appetite in individuals with certain medical conditions associated with decreased appetite, such as cancer-related cachexia and other wasting disorders.
  6. Improved Sleep Quality: Some users report improved sleep quality and better REM sleep when taking MK677, although individual responses can vary.

What Are the Common Side Effects of MK677?

Individual responses to MK677 can vary, and not everyone will experience all of these side effects. If someone is considering using MK677, it is vital to consult a healthcare professional to understand the potential risks and benefits based on their specific health profile. Additionally, proper dosage, timing, and cycling should be carefully considered to mitigate potential side effects.

  • Increased Appetite: MK677 is known to stimulate appetite, and some individuals may experience a significant increase in hunger while taking the compound.
  • Water Retention: Users may notice water retention or mild edema, which can lead to a bloated feeling or temporary weight gain.
  • Lethargy/Fatigue: Some individuals report feeling more tired or lethargic while taking MK677, which can be a result of hormonal changes or other factors.
  • Numbness or Tingling in Extremities: MK677 has been associated with a sensation of numbness or tingling in the hands and feet for some users.
  • Changes in Blood Sugar Levels: MK677 may cause fluctuations in blood sugar levels, particularly in individuals with existing glucose regulation issues.
Pumping Iron Ibutamoren (MK-677) 10mg x 60 Capsules
Pumping Iron Ibutamoren (MK-677) 10mg x 60 Capsules

Best Time to Take MK677: Morning vs Night Time

The best time to take MK677 depends on personal preferences, lifestyle, and the ability to manage its potential side effects. Some individuals may even choose to split their daily dosage, taking a portion in the morning and the rest before bedtime.

As you will see below, there are certain considerations to keep in mind and for each person, it will be a different experience. It is best advised to try the different protocols and decide for yourself which option works best for you:

Morning Administration:

  • May cause slight lethargy or decreased energy levels during the day
  • May cause slight appetite increase during the day
  • Some individuals prefer taking MK677 in the morning because their daily activities or busy work schedule allows easier management of appetite and energy levels
  • However, for other individuals, the increased appetite could be more noticeable during waking hours, and may be more challenging for those aiming to control their food intake or follow a specific diet plan

Nighttime Administration:

  • Some users find that taking MK677 before bedtime helps them better cope with the lethargy/fatigue side effect, as they can rest and sleep through this sensation
  • The growth hormone release stimulated by MK677 might be more in line with the body’s natural patterns, as growth hormone levels tend to peak during sleep
  • Some individuals prefer nighttime dosing so that they can sleep through some of the increased appetite side-effects
  • However, some individuals may find that dosing before bed will increase appetite enough to make it more difficult to fall asleep
  • The increased appetite associated with MK677 might be more noticeable in the evening, which could lead to overeating if not managed.

How Does Timing MK677 With Exercise or Training Sessions Impact Its Benefits?

The best time to take MK677 around your exercise or training sessions can have potential impacts on its benefits due to its ability to stimulate growth hormone release. Here are some considerations:

  1. Enhanced Recovery: Taking MK677 around the time of exercise or training sessions may promote enhanced recovery. Growth hormone plays a crucial role in tissue repair and muscle recovery, so increasing its levels during or after workouts might aid in the recovery process.
  2. Muscle Growth and Repair: MK677’s ability to increase growth hormone and IGF-1 levels can be particularly beneficial during periods of intense exercise, as it may support muscle growth and repair, leading to more significant gains in muscle mass over time.
  3. Increased Fat Loss: Some studies suggest that MK677 can aid in fat loss due to its effects on growth hormone and IGF-1, which may promote lipolysis (the breakdown of fat). Timing MK677 near workouts could potentially enhance fat-burning effects, especially in combination with appropriate exercise and diet.
  4. Strength and Performance: By optimizing growth hormone levels, MK677 may positively impact strength and performance, making it useful to take before strength training or high-intensity workouts to potentially enhance performance.
  5. Sleep and Recovery: As MK677 may cause lethargy or fatigue as a side effect, taking it at night after exercise might be more convenient for some individuals, as they can rest and sleep through this period, aiding overall recovery.
  6. Potential Appetite Stimulation: Timing MK677 around exercise might help manage the increased appetite side effect, as users can utilize the extra caloric intake to support their fitness goals, especially for individuals aiming to gain muscle mass.

Best Time to Take MK677: Will Timing Affect MK677 Effectiveness?

The best time to take MK677 is different for each individual and the best way is the way that works for you.

The effectiveness of MK677 will not be affected so much that it would be noticeable, so whichever way you choose, it will work and will be very effective.

However, if you want to understand more about timing and any influence to its effectiveness, here are some considerations:

  1. Growth Hormone Release: MK677 stimulates the release of growth hormone, and the body’s natural production of growth hormone tends to peak during certain periods, particularly during sleep. Taking MK677 at night might align with the body’s natural rhythm, potentially maximizing its impact on growth hormone levels.
  2. Sleep Disturbances: Some users report experiencing lethargy or fatigue as a side effect of MK677. Taking it at night might be more suitable for these individuals since they can rest and sleep through this period, potentially minimizing the impact of this side effect on daily activities.
  3. Appetite Stimulation: MK677 is known to increase appetite in many users. Taking it in the morning might be preferred by some individuals as they can manage the increased hunger throughout the day, while others might choose to take it later in the day to minimize the impact on their appetite during waking hours.
  4. Exercise and Training: Some users prefer to time their MK677 intake around their exercise or training sessions. By doing so, they might take advantage of its potential benefits on recovery, muscle growth, and performance. However, other users will find that the slight fatigue will negatively impact their motivation levels.

Should MK677 Be Taken With or Without Food?

MK677 (Ibutamoren) can be taken with or without food, as it does not require a specific type of administration in this regard. However, there are some considerations to keep in mind for each option:

  1. Taking MK677 with Food:
    • Advantages: Some users find that taking MK677 with a meal can help minimize potential stomach discomfort or nausea that might occur with its use.
    • Considerations: Taking MK677 with a meal could potentially slow down its absorption and onset of action, although this might not be a significant concern for most users.
  2. Taking MK677 on an Empty Stomach:
    • Advantages: Taking MK677 on an empty stomach might lead to quicker absorption and potentially faster effects, especially if you want to avoid any delay in its action.
    • Considerations: Some individuals may experience mild stomach discomfort or nausea when taking MK677 on an empty stomach, although this can vary between users.

What Is the Recommended Dosage of MK677?

The recommended dosage of MK677 (Ibutamoren) can vary depending on factors such as individual tolerance, experience with the compound, and specific health goals. It’s crucial to note that I am an AI language model, and I am not a medical professional. Therefore, I cannot provide personalized medical advice. However, I can provide some general dosage guidelines that are commonly referenced:

  • Typical Dosage Range: The typical dosage of MK677 for adults is usually in the range of 10 mg to 25 mg per day.
  • Start Low and Gradually Increase: It’s common for users to start with a lower dosage, such as 10 mg, and gradually increase the dose over time if needed, based on their response and tolerance to the compound.
  • Cycle Length: MK677 is often used in cycles, typically ranging from 8 to 12 weeks. After completing a cycle, it is recommended to take a break to allow the body to readjust before starting another cycle.

Are There Any Benefits of Splitting the MK677 Dosage Throughout the Day?

Some users choose to split the dosage of MK677, dosing once in the morning and once in the evening.

  1. Potential Mitigation of Side Effects: By dividing the daily dosage into multiple smaller doses, some individuals might experience a reduction in certain side effects associated with MK677, such as water retention and bloating.
  2. Improved Tolerance: For those who find higher single doses of MK677 uncomfortable or challenging to tolerate, splitting the dosage can make it easier on their digestive system and improve overall compliance.
  3. Optimal Hormonal Levels: Splitting the dosage can help maintain more consistent growth hormone and IGF-1 levels throughout the day, potentially maximizing the desired effects.
  4. Individualized Timing: Splitting the dosage allows users to tailor the timing of administration to their unique schedule and lifestyle, optimizing its effects based on their preferences and routines.
  5. Reduced Risk of Oversaturation: Some users believe that smaller, more frequent doses of MK677 are less likely to oversaturate the body’s receptors and lead to diminished effectiveness over time.

How Long Does MK677 Take To Start Showing Results When Taken at Different Times?

The time it takes for MK677 (Ibutamoren) to start showing results can vary from person to person and is influenced by various factors, including the individual’s physiology, dosage, and timing of administration. Here are some general guidelines on when users might start noticing effects based on different timing scenarios:

  1. Morning Administration: When taken in the morning, some users might experience increased appetite and potentially increased energy levels during the day relatively quickly, within a few days to a week. However, noticeable changes in muscle mass, strength, or body composition may take several weeks to a couple of months, as these effects typically occur gradually over time.
  2. Nighttime Administration: When taken at night, individuals might experience potential sleep disturbances, such as lethargy or fatigue, during the initial days of usage. Other effects, such as enhanced recovery and potential improvements in muscle mass and fat loss, may become apparent after several weeks to a few months of consistent use.

It’s important to note that MK677 is not a quick-fix supplement, and individual responses can vary significantly. Some users might see noticeable changes earlier, while others might require more time to experience the full effects.

Moreover, the benefits of MK677 are often seen when it is used in conjunction with a well-structured diet and appropriate exercise regimen. Consistency with dosing and lifestyle factors will play a role in determining how quickly results manifest.

As with any supplement, it’s essential to manage expectations and not solely rely on MK677 to achieve specific fitness goals.

Is There an Ideal Time To Take MK677 for Maximising Muscle Growth?

There is no universally agreed-upon “best time to take MK677” for maximising muscle growth, as individual responses can vary based on several factors.

However, there is one consideration to keep in mind when using MK677 to support muscle growth:


Whatever time you choose to take MK677, it’s essential to be consistent with the timing every day to maintain steady growth hormone levels and optimize its effects on muscle growth.

Consistency is crucial with MK677 for optimal results primarily because of its relatively long half-life, which is approximately 24 hours.

The half-life refers to the time it takes for half of the drug to be eliminated from the body. Since MK677 has a long half-life, maintaining regularity in dosing ensures a steady and sustained presence of the compound in the bloodstream.

This consistency is essential for maintaining stable growth hormone levels throughout the day, as MK677 stimulates the release of growth hormone and insulin-like growth factor 1 (IGF-1).

By adhering to a consistent dosing schedule, users can potentially maximize the impact of MK677 on muscle growth, recovery, and other desired outcomes, as fluctuations in dosing could result in uneven hormonal effects.

Moreover, consistent dosing allows the body to adjust and optimize its response to MK677 over time, contributing to more predictable and potentially more significant benefits.

Ultimately, the best time to take MK677 is at a consistent time every 24 hours.

Does Taking MK677 at Specific Times Influence Its Impact on Fat Loss?

Taking MK677 (Ibutamoren) at specific times may influence its impact on fat loss, primarily due to its effects on growth hormone and insulin-like growth factor 1 (IGF-1). However, it’s important to note that the effects of MK677 on fat loss can vary from person to person, and individual responses may differ. Here are some considerations regarding the timing of MK677 administration and its potential influence on fat loss:

  1. Nighttime Administration: Some users prefer taking MK677 at night, as it might help manage the side effects, such as increased appetite or lethargy, during waking hours. Additionally, growth hormone levels naturally peak during sleep, and nighttime administration might align with the body’s natural rhythms, potentially enhancing the fat-burning effects during this period.
  2. Before or After Exercise: Taking MK677 before exercise might provide benefits for fat loss, as elevated growth hormone levels can enhance lipolysis (breakdown of fat) during physical activity. On the other hand, taking MK677 after exercise might support the recovery process, which is essential for overall fat loss and body composition improvements.
  3. Consistency and Individual Response: While timing may play a role, consistency in MK677 administration and individual response to the compound are crucial factors. Some individuals might experience more pronounced fat loss effects with MK677, while others may not see significant changes in body composition.
  4. Diet and Exercise Synergy: MK677 is not a magic pill for fat loss, and its effects are most likely to be enhanced when combined with a proper diet and exercise program aimed at fat loss and body composition improvements.
  5. Appetite Stimulation: MK677 is known to increase appetite in many users. The timing of MK677 administration may affect how this increased appetite is managed and incorporated into the overall diet strategy for fat loss.

It is essential to keep in mind that while MK677 might have some potential effects on fat loss due to its influence on growth hormone and IGF-1, it is not a substitute for lifestyle changes or a well-balanced approach to weight management.

SR9009 All Your Questions Answered (Video)

SR9009 – Complete Guide to Stenabolic (Video)

SR9009, also known as Stenabolic, has gained notoriety in the bodybuilding community as “exercise in a bottle” – could this be the key to athletic performance and fat loss? Be sure to check out this video from Albina (SimplyFit London) to answer all your questions about this extraordinary compound.

What is SR9009?

SR9009, also known as Stenabolic, is a research drug that was developed by professor Thomas Burris of the Scripps Research Institute as an agonist of Rev-ErbA

This metabolic modulator has become increasingly popular in the fitness and bodybuilding communities. It works by binding to the Rev-erb protein, which plays a role in regulating the body’s internal clock. By doing so, SR9009 can activate certain genes that help regulate metabolism, leading to increased energy expenditure and fat loss. Additionally, it is believed to increase endurance and stamina, allowing athletes to train harder and longer.

Let’s take a closer look at this mysterious compound and its potential benefits for athletes.

How Does SR9009 Work?

SR9009 works by binding to the Rev-erb protein, which is responsible for regulating metabolism, lipid homeostasis, circadian rhythm (sleep/wake cycle), stress response, and other key functions of the human body. When SR-9009 binds to this protein, it activates certain genes that help regulate metabolism. This leads to increased energy expenditure, improved fat loss, increased endurance levels, and more efficient glucose uptake into muscle cells—all of which are beneficial for athletes who want to improve their performance.

What Are the Benefits of Taking SR9009?

When taken as directed (under medical supervision), there are several potential benefits associated with taking SR-9009:

  • Improved Endurance & Stamina – Because of its ability to stimulate energy expenditure and metabolic rate, taking SR- 9009 can lead to improved endurance levels during exercise or athletic activities. Additionally, those who take it may experience an increase in their stamina levels due to improved glucose uptake into muscle cells—allowing them to work out longer without feeling fatigued.
  • Increased Fat Loss – As mentioned previously, one of the primary ways that SR-900 9 increases energy expenditure is by stimulating fat loss—which can be beneficial for athletes looking to improve their physique or performance level.
  • Improved Muscle Growth & Strength – Due in part to its ability to improve glucose uptake into muscle cells, taking SR 900 9 can also lead to improved muscle growth & strength—which are essential for athletic performance improvement.

SR9009 FAQ

  1. What is SR9009?

SR9009, also known as Stenabolic, is a synthetic compound, known as a metabolic modulator, which was developed to study the circadian rhythm.

  1. How does SR-9009 work?

SR-9009 works by binding to the Rev-erb protein, which plays a role in regulating the body’s internal clock. By binding to this protein, SR-9009 can activate certain genes that help regulate metabolism, leading to increased energy expenditure and fat loss.

  1. What are the benefits of SR-9009?

The potential benefits of SR-9009 include increased energy expenditure, fat loss, improved endurance and stamina, and improved sleep quality.

  1. Is SR-9009 legal?

SR-9009 is currently not approved for human consumption but is not illegal for research purposes.

  1. Is SR-9009 a steroid?

No, SR-9009 is not a steroid.

  1. Can SR-9009 help with weight loss?

Yes, SR-9009 may help with weight loss by increasing energy expenditure and fat loss. It also has been shown to reduce the amount of cholesterol, triglycerides, insulin and free fatty acids.

  1. What are the potential side effects of SR-9009?

The potential side effects of SR-9009 may include nausea, insomnia, and headaches.

  1. How should SR-9009 be dosed?

The dosing recommendations for SR-9009 vary and are still being studied. However, most researchers will use 10-30mg per day.

  1. How long does it take for SR-9009 to work?

The timeline for SR-9009 to work is not well-established, as research on the compound is still ongoing. However, most research studies show that results begin to show within 1-2 weeks.

  1. Can SR-9009 improve endurance and stamina?

Yes, SR-9009 may improve endurance and stamina by increasing energy expenditure and fat loss.

  1. Can SR-9009 improve sleep quality?

There is some evidence to suggest that SR-9009 may improve sleep quality, but more research is needed to confirm this.

  1. Can SR-9009 cause liver damage?

The long-term effects of SR-9009 on liver function are not well-established, as research on the compound is still ongoing. However, no reports have suggested liver damage.

  1. Is SR-9009 safe for women to use?

Yes, SR9009 can be used by women and does not affect the sex hormones.

  1. Can SR-9009 be stacked with other supplements?

SR9009 is most often stacked alongside GW-501516 but can be used with any other SARM or supplement.

  1. Can SR-9009 be detected in drug tests?

Not most drug tests. However, SR9009 is banned by WADA and can not be used in professional sport or in any tested competitions – that includes drug tested bodybuilding contests.

  1. Is SR-9009 available in capsule form?

SR-9009 is available in various forms, including capsules and liquid.

  1. Can SR-9009 be purchased online?

Yes, SR-9009 can be purchased online from various retailers.

  1. Is SR-9009 a prescription drug?

No, SR-9009 is not a prescription drug.

  1. What is the recommended cycle length for SR-9009?

The recommended cycle length for SR-9009 varies and is still being studied. It is important to speak with a healthcare professional before using any performance-enhancing drug or supplement.

  1. Is SR-9009 effective for bodybuilding?

The effectiveness of SR-9009 for bodybuilding is not well-established, as research on the compound is still ongoing.


In conclusion, while further research is needed on the long term effects of using SARM compounds like SR 900 9 on humans; when used properly under medical supervision it appears that there are numerous potential benefits associated with using this compound – such as increased fat loss; improved endurance & stamina; as well as enhanced muscle growth & strength – all of which could be helpful for athletes looking for an edge over their competition. Just remember: always consult your doctor before starting any new supplement or medication program! With proper guidance from a professional healthcare provider you can decide if this type of product is right for you!

Glucose Disposal Agent: Ultimate Guide to Shredded Gains (2023)

Glucose Disposal Agent: Ultimate Guide to Shredded Gains (2024)

A high quality Glucose Disposal Agent (GDA) supplement can be the game-changer in your quest for shredded gains. A GDA can improve insulin sensitivity, enhance glucose uptake into muscle cells, and promote glycogen synthesis. By improving nutrient partitioning and reducing fat storage, GDAs have garnered heavy interest among bodybuilders and athletes, and for very good reason. Here’s the ultimate guide to help you utilise this amazing supplement to take your progress to the next level.

What is a Glucose Disposal Agent?

A Glucose Disposal Agent supplement is designed to improve the way the body manages glucose (blood sugar) levels. The primary goal of a GDA is to enhance insulin sensitivity and facilitate the transportation of glucose into muscle cells, rather than storing it as fat. GDAs have gained popularity in the fitness and bodybuilding communities due to their potential benefits in improving nutrient partitioning, enhancing muscle gains, and promoting fat loss.

How does a Glucose Disposal Agent work?

1. Insulin and Glucose Metabolism: Before delving into glucose disposal agents, it’s essential to understand insulin’s role in glucose metabolism. Insulin is a hormone secreted by the pancreas in response to elevated blood glucose levels, such as after eating a meal containing carbohydrates. Insulin acts as a “key” that allows glucose to enter cells, where it can be used for energy or stored for future use.

Insulin resistance is a condition where cells become less responsive to insulin, leading to higher blood glucose levels. When insulin resistance occurs, the body compensates by producing more insulin, potentially leading to chronically elevated insulin levels. High insulin levels can contribute to fat storage and other metabolic issues.

2. Mechanism of Glucose Disposal Agents: GDAs work to improve insulin sensitivity, which means they help cells respond more effectively to insulin’s signaling. They may do this through various mechanisms, including:

a. GLUT4 Translocation: One of the primary mechanisms involves promoting the translocation of glucose transporter type 4 (GLUT4) to the cell surface. GLUT4 is responsible for facilitating glucose entry into muscle and fat cells. GDAs may enhance this process, allowing more glucose to be transported into muscle cells for energy use and glycogen storage, rather than being converted to fat.

b. Increased Glycogen Synthesis: GDAs can stimulate the synthesis of glycogen, the stored form of glucose in muscles and the liver. Increased glycogen storage can enhance endurance, strength, and recovery during workouts.

c. Inhibition of Glucose Production: Some GDAs may also reduce the liver’s production of glucose, further aiding in maintaining balanced blood sugar levels.

d. Enhanced Fat Oxidation: Some GDAs have been proposed to promote fat oxidation (fat burning) and reduce fat storage by improving insulin sensitivity.

What are the best Glucose Disposal Agents on the market?

Several ingredients have been researched and shown promising results as Glucose Disposal Agents in terms of improving insulin sensitivity and glucose uptake into cells. Here are some of the best GDA ingredients known at that time:

  1. Alpha-Lipoic Acid (ALA): ALA is a potent antioxidant that has been extensively studied for its potential benefits in improving insulin sensitivity. It may enhance glucose uptake into cells and reduce oxidative stress, making it one of the popular GDA ingredients.
  2. Berberine: Berberine is a bioactive compound found in several plants. It has been used in traditional medicine for various purposes, including improving glucose metabolism and insulin sensitivity. Studies suggest that berberine activates AMP-activated protein kinase (AMPK), which plays a role in glucose uptake and energy regulation.
  3. Cinnamon Extract: Cinnamon is a popular spice known for its potential to improve insulin sensitivity. Cinnamon extracts, particularly those high in bioactive compounds like cinnamaldehyde, have been studied for their glucose-lowering effects.
  4. Fenugreek: Fenugreek is an herb that has been researched for its potential to lower blood sugar levels and improve insulin sensitivity. It contains soluble fiber and compounds like trigonelline that may contribute to its GDA properties.
  5. Chromium: Chromium is an essential mineral that plays a role in carbohydrate and lipid metabolism. Some studies suggest that chromium supplementation may improve insulin sensitivity and glucose disposal.
  6. Bitter Melon (Momordica charantia): Bitter melon is a tropical fruit that has been traditionally used in various cultures to manage blood sugar levels. It contains compounds with potential GDA properties, such as charantin and polypeptide-p.
  7. Gymnema Sylvestre: Gymnema sylvestre is an herb known as the “sugar destroyer.” It has been used in traditional medicine for its potential to reduce sugar absorption in the intestine and enhance insulin function.
  8. R-Alpha-Lipoic Acid (R-ALA): R-ALA is the biologically active form of alpha-lipoic acid. Some studies suggest that R-ALA may be more effective than the regular form in improving insulin sensitivity and glucose uptake.
  9. Vanadium: Vanadium is a trace mineral that has been studied for its potential insulin-like effects, which may help improve glucose metabolism.
  10. Chitosan: Chitosan is a fiber derived from the shells of crustaceans. Some research suggests that it may improve insulin sensitivity and reduce blood sugar levels.

Does a Glucose Disposal Agent help with muscle growth?

A high quality Glucose Disposal Agent can contribute to muscle growth by improving nutrient partitioning and enhancing insulin sensitivity. While GDAs themselves do not directly promote muscle growth like traditional muscle-building supplements (e.g., protein powders, creatine), they can play a supportive role in the process. Here’s how a glucose disposal agent may help with muscle growth:

1. Improved Nutrient Partitioning: Nutrient partitioning refers to how the body allocates and utilizes nutrients, such as carbohydrates and amino acids. GDAs may help direct a larger portion of the nutrients, particularly glucose and amino acids, toward muscle cells for growth and repair instead of storing them as fat. This can create a more favorable environment for muscle development.

2. Increased Glycogen Storage: GDAs can enhance glycogen synthesis, the storage form of glucose in muscles and the liver. Having ample glycogen reserves is essential for providing energy during workouts and promoting muscle recovery and growth post-exercise.

3. Enhanced Insulin Sensitivity: GDAs work to improve insulin sensitivity, which means the body becomes more responsive to insulin’s signaling. Higher insulin sensitivity allows for more efficient nutrient uptake into muscle cells, especially after a meal, when nutrient absorption is essential for muscle recovery and growth.

4. Better Post-Workout Recovery: By promoting better nutrient uptake and glycogen storage, GDAs can aid in post-workout recovery. Enhanced recovery supports muscle repair and growth, as muscles often grow stronger during the recovery phase.

5. Potential Reduction in Fat Gain: Some GDAs have been associated with reduced fat storage and improved fat oxidation. By minimizing fat gain and promoting a leaner body composition, GDAs may indirectly enhance the appearance of muscle definition.

Can GDAs improve insulin sensitivity?

Yes, Glucose Disposal Agents can improve insulin sensitivity. In fact, improving insulin sensitivity is one of the main mechanisms through which GDAs are believed to exert their effects.

Insulin sensitivity refers to how responsive the cells in your body are to insulin’s signaling. When you have good insulin sensitivity, your cells effectively take up glucose from the bloodstream in response to insulin, helping to regulate blood sugar levels. On the other hand, insulin resistance occurs when cells become less responsive to insulin, leading to higher blood sugar levels and potentially contributing to various metabolic issues, including type 2 diabetes and weight gain.

GDAs work to enhance insulin sensitivity through various mechanisms, including:

1. GLUT4 Translocation: One of the primary mechanisms involves promoting the translocation of glucose transporter type 4 (GLUT4) to the cell surface. GLUT4 is responsible for transporting glucose into cells, particularly muscle and fat cells. GDAs may enhance this process, making cells more responsive to insulin and improving glucose uptake.

2. Activation of AMPK: Some GDAs, such as berberine, have been shown to activate AMP-activated protein kinase (AMPK). AMPK is an enzyme that plays a crucial role in energy regulation and metabolism. Activating AMPK can enhance insulin sensitivity and glucose uptake into cells.

3. Reduced Gluconeogenesis: GDAs may help reduce the liver’s production of glucose, a process known as gluconeogenesis. By limiting excess glucose production, blood sugar levels can be better controlled, reducing the demand for insulin.

4. Improved Fat Oxidation: Some GDAs have been associated with increased fat oxidation (fat burning), which can help reduce intracellular lipid accumulation and improve insulin sensitivity.

By improving insulin sensitivity, GDAs help the body more efficiently manage glucose, which can have several benefits, including:

  • Lowering blood sugar levels and reducing the risk of type 2 diabetes.
  • Promoting better nutrient partitioning, directing nutrients like glucose and amino acids toward muscle cells for growth and recovery.
  • Enhancing glycogen storage in muscles, improving exercise performance and recovery.
  • Supporting weight management and reducing the likelihood of excess fat storage.

Are there any side effects from Glucose Disposal Agents?

Glucose Disposal Agents are generally considered safe for most healthy individuals when used as directed. However, like any supplement, GDAs may have potential side effects, especially when taken in excessive amounts or by individuals with certain medical conditions. It’s essential to be aware of possible side effects and consult with a healthcare professional before using GDAs, particularly if you have any underlying health issues or are taking medications. Some potential side effects include:

  1. Hypoglycemia, more likely to occur if GDAs are taken alongside medications or other supplements that lower blood sugar levels
  2. Digestive Issues such as bloating and gastrointestinal discomfort
  3. Allergic Reactions in some people
  4. Liver and Kidney Function at high doses and extended periods of time

When is the best time to take a Glucose Disposal Agent?

The best time to take a Glucose Disposal Agent can vary depending on your specific goals and individual needs. It is essential to follow the manufacturer’s instructions and, if available, consult with a healthcare professional or a certified nutritionist for personalized guidance. Here are some general guidelines for when to take a GDA:

1. With Carbohydrate-Containing Meals: GDAs are commonly taken with meals that contain carbohydrates. This is because GDAs are designed to help improve insulin sensitivity and enhance glucose uptake into cells, particularly muscle cells. Taking GDAs with carbohydrate-rich meals can optimize their effects on nutrient partitioning, directing glucose and nutrients toward muscle cells for potential muscle growth and recovery.

2. Pre-Workout: Some individuals prefer taking GDAs before their workout, especially if they are consuming a pre-workout meal that includes carbohydrates. The idea behind this approach is to enhance nutrient delivery and glycogen storage in muscles, providing extra energy for the upcoming workout.

3. Post-Workout: Others choose to take GDAs post-workout, along with a post-workout meal or shake containing carbohydrates and protein. This can aid in replenishing glycogen stores in muscles and facilitating recovery and muscle repair.

4. During High-Carb Days: For individuals following a cyclical or targeted ketogenic diet, where they have designated days of higher carbohydrate intake, taking a GDA on those high-carb days may help manage blood sugar levels and promote nutrient uptake.

5. On Refeed Days: Similarly, individuals who follow intermittent fasting or calorie-restricted diets might incorporate “refeed” days or meals where they consume higher amounts of carbohydrates. Taking GDAs on these refeed occasions can support the body’s response to the sudden increase in glucose intake.

6. Before Cheat Meals: Some individuals use GDAs before cheat meals or larger indulgent meals to help manage blood sugar levels and potentially minimize the impact of excess carbohydrates.

To maximize the benefits, it’s crucial to maintain a balanced diet, engage in regular exercise, and consider other lifestyle factors that can influence insulin sensitivity and glucose metabolism.

Enhanced Labs SLIN (120 Capsules)
Enhanced Labs SLIN (120 Capsules)

Can a glucose disposal agent help with fat loss?

While GDAs themselves do not directly promote fat loss like traditional fat burners or thermogenic supplements, their effects on insulin sensitivity and glucose metabolism may offer some benefits for individuals aiming to lose body fat. Here’s how GDAs may be related to fat loss:

1. Improved Nutrient Partitioning: By enhancing nutrient partitioning, GDAs may help reduce the amount of glucose and nutrients being stored as fat and instead direct them toward muscle cells. This can create a more favorable environment for maintaining or increasing lean muscle mass while reducing fat storage.

2. Reduced Fat Gain: GDAs may potentially minimize the impact of high-carbohydrate meals on fat storage. By improving insulin sensitivity, GDAs can help prevent excessive spikes in blood sugar levels and the subsequent release of insulin, which is associated with fat storage.

3. Increased Muscle Mass: As GDAs support muscle growth and recovery by promoting glucose uptake into muscle cells, having more lean muscle mass can contribute to a higher resting metabolic rate, potentially aiding in fat loss efforts.

4. Energy Utilization: GDAs may help improve the body’s ability to utilize glucose for energy during exercise. This can enhance workout performance and calorie expenditure during physical activity, which may contribute to fat loss.

Are GDAs suitable for individuals with diabetes?

The use of Glucose Disposal Agents in individuals with diabetes should be approached with caution, and it’s essential to consult with a healthcare professional before considering their use. GDAs can have effects on glucose metabolism, insulin sensitivity, and blood sugar levels, which may interact with medications and the individual’s existing diabetes management plan.

Are GDAs effective for post-workout recovery?

A Glucose Disposal Agent can play a supportive role in post-workout recovery, but their effectiveness may depend on various factors and individual responses. GDAs primarily work by improving insulin sensitivity and promoting the uptake of glucose into cells, particularly muscle cells. This can have several potential benefits for post-workout recovery:

1. Glycogen Replenishment: After a workout, muscles may have depleted their glycogen stores, which are the stored form of glucose used for energy during exercise. GDAs may enhance glycogen synthesis, facilitating the replenishment of glycogen in muscle cells, leading to faster recovery and improved performance for subsequent workouts.

2. Nutrient Uptake: GDAs can improve nutrient partitioning, directing glucose and nutrients toward muscle cells rather than fat cells. This can facilitate the uptake of essential nutrients, such as amino acids from protein, into muscle tissue for repair and recovery.

3. Insulin Response: GDAs may support a more controlled and efficient insulin response after a workout. Proper insulin sensitivity can help manage blood sugar levels and optimize nutrient delivery to muscles, aiding in recovery and reducing the risk of excessive fat storage.

4. Reduced Muscle Soreness: Enhanced post-workout nutrient uptake and glycogen replenishment can contribute to reduced muscle soreness and faster recovery between workouts.

However, it’s important to note that GDAs are not a substitute for a well-rounded post-workout recovery plan. The most critical factors for effective post-workout recovery include:

1. Nutrition: Consuming a balanced meal or post-workout shake that includes protein, carbohydrates, and some healthy fats can support muscle recovery and glycogen replenishment.

2. Hydration: Proper hydration is crucial for overall recovery and performance. Drink enough water throughout the day and after workouts.

3. Rest and Sleep: Allow sufficient time for rest and recovery between intense workouts. Sleep is a critical component of the recovery process.

4. Active Recovery: Engage in light activities like walking or gentle stretching to promote blood flow to muscles and reduce stiffness.

5. Protein Intake: Ensure you consume an adequate amount of protein to support muscle repair and growth.

GDAs can be used as part of a post-workout recovery strategy to optimize nutrient uptake and glycogen replenishment. However, individual responses may vary, and their effects should be considered alongside other essential recovery practices.

How long does a Glucose Disposal Agent take to show results?

The time it takes to see results from using Glucose Disposal Agent can vary depending on several factors, including individual physiology, diet, exercise regimen, and the specific GDA being used. As with most supplements, results are not typically instantaneous, and patience and consistency are essential.

10 Surprising Benefits of MK-677 (Ibutamoren): Side Effects, Dosage, Timing (2023)

10 Surprising Benefits of MK-677: Side Effects, Dosage Review (2024)

10 Surprising Benefits of MK-677 – here is the low down with full review of the possible side effects, correct dosages and timing.

For serious athletes looking to optimise performance, MK 677 may be the answer. This popular product is a growth hormone secretagogue with powerful effects on one’s IGF-1 and GH levels – two hormones crucial for building strong muscles. Forget SARMs; you need this “secret” agent if you’re ready to take your bodybuilding game up a notch!

What is MK-677?

MK-677, also known as Ibutamoren, is a powerful growth hormone secretagogue that can help boost muscle tissue development. It has gained popularity in recent years amongst bodybuilders and gym fans for its natural ability to aid in the production of growth hormones without interfering with other biological processes.

MK-677 has been clinically studied and proven to be effective at assisting with hormone deficiencies such as reduced bone density, while at the same time providing short-term anabolic effects.  Additionally, it can also be used as a nootropic agent (a drug or supplement used to improve cognitive functioning), helping users with improved sleep and cognitive function.

How does MK-677 Work?

MK-677 works by binding to receptors in the brain that are responsible for releasing hormones like Growth Hormone (GH) and Insulin Like Growth Factor 1 (IGF-1). By doing this, it increases the body’s natural release of these hormones which help to promote healthy fat loss and muscle gain.

For those looking to build muscle or lose weight, this can prove extremely beneficial since GH helps stimulate protein synthesis and IGF-1 helps promote cell growth in muscles; leading to improved athletic performance.

Additionally, since it does not interfere with other biological processes or cause testosterone suppression – unlike other steroids – MK 677 is considered safe for long term use.

MK-677 Dosage and Timing

When taking MK 677, its 24-hour half life should be considered carefully. With an initial spike in growth hormone levels, you may find yourself feeling lethargic and drowsy further down the line. Our suggestion? Split your dose into two or take it all before bed – that way you can power through the day without sacrificing a good night’s rest!

Pumping Iron Ibutamoren (MK-677) 10mg x 60 Capsules
Pumping Iron Ibutamoren (MK-677) 10mg x 60


Read on to see the 10 Surprising Benefits of MK-677 making it the best-selling supplement today.

10 Surprising Benefits of MK-677

MK-677 has been coined the ‘fountain of youth’ – and rightfully so! This powerful compound not only aids in cultivating muscle mass and muscular strength; it can also promote overall wellbeing and cognitive function – transforming your body from the inside out. Here are 10 surprising benefits of MK-677:

1. Building Lean Muscle Mass

MK 677 has been suggested to be a powerful stimulant for muscle growth. Studies suggest it can trigger the production of two hormones which act in synergy – growth hormone and IGF-1 from your pituitary gland and liver respectively. This action could lead to an increase in strength, improved recovery time as well as positive changes on body composition (6-8lbs of extra lean mass over 6- 8 weeks based on oral doses).

A study conducted with 24 obese men revealed impressive results such as increased basal metabolic rate upon taking MK677 twice daily for 2 months.

2. Prevents Muscle Catabolism

An exciting study recently revealed that MK 677, a treatment option for reversing muscle wasting and protein loss, brought about remarkable improvements in elderly patients with hip fractures. Even more enthralling was the fact it already demonstrated success when tested on 8 food-deprived volunteers during an intensive double blind control trial – showing great promise as a viable solution to improve physical health.

3. Increases Fat Loss

Growth hormones are probably the only hormone which can help you to burn both visceral AND subcutaneous fat whilst helping you to build up lean muscle mass.

4. Improves Bone Density

Ibutamoren has shown promising evidence in the fight against bone-related conditions. It works by firstly reducing and then increasing turnover rate of bones over a period of 12 months, helping to strengthen them overall.

Studies have seen positive results when taken by obese men as well as elderly participants aged 65 years or more; all showing improved bone health and density – making it an ideal choice for treatment such as osteoporosis. Women too can benefit from this revolutionary new supplement with clinical studies reporting stronger mineral densities post-menopausal women taking MK 677 supplements!

5. Promotes Quality of Sleep

Get a good night’s sleep and gain strength even faster with MK 677, an effective nootropic that may improve both the length and quality of your REM cycle. With its neuroprotective properties supporting heightened cognitive function, take advantage of this supplement for not only better rest but improved health too!

6. Improves Hair, Skin and Nails

MK-677 can do wonders for your skin and hair – even in low doses! Studies have shown that GH has the power to revitalise your complexion whilst also strengthening the hair, skin and nails… giving you a healthier glow.

7. Promotes GH Longevity

After reaching adulthood, our bodies naturally produce less Growth Hormone (GH). To combat this shrinkage of GH levels in elderly men, researchers put 65 participants on a daily dose regimen of MK-677 – the results were staggering. These brave volunteers experienced an increase to their IGF-1 and GH numbers after only a month!

8. Improves Brain Function

MK-677 has the potential to unleash your full cognitive potential. Studies have shown that its two primary functions can drastically improve memory and learning, increase IGF-1 levels, as well as facilitate deep REM sleep – essential for optimal brain health. Take the steps towards better mental power today!

9. Prevent Growth Hormone Deficiency in Children

Studies have demonstrated that MK-677 can effectively boost key hormones in children with hormone deficiencies.

It has the potential to prevent growth issues without interfering with other important bodily functions like insulin, cortisol and thyrotropin production; making it a great treatment option for young people struggling to grow.

However, adults may not be so lucky as research found elevated levels of glucose or insulin when utilising this therapy – meaning further caution is advised before use by those over 18 years old.

10. Speeds up Recovery, Healing and Injury Repair

MK-677 promotes rapid recovery and injury repair by boosting Growth Hormone (GH) levels. This helps rebuild damaged tissues quickly, allowing athletes to get back in the game sooner than expected!

MK-677 Side Effects

MK 677 has become a popular supplement for bodybuilders, gym fanatics, and fitness buffs alike. In theory, it sounds like the perfect supplement – no testosterone suppression, no aromatization, nothing. But is MK 677 entirely safe? Let’s take a look at what you need to know about side effects and dosages before deciding if this is the right supplement for you.

Possible Side Effects of High Dosage

In completely healthy individuals, MK 677 is considered safe. The only possible side effects you may experience are muscle cramps, increased appetite and edema; these usually only crop up when you’ve taken too high a dosage of Ibutamoren. They will naturally disappear once you stop taking MK-677.

Side Effects in Healthy Individuals

When taken in recommended doses (between 10mg-25mg per day), Ibutamoren should be relatively free of side effects for healthy adults who are looking to boost their HGH levels without resorting to injections or other more risky methods such as steroids or growth hormone stimulants.

It should be noted that women tend to require smaller amounts than men due to their lower tolerance level; they should start with 5mg per day and gradually work up from there – never exceeding 25mg per day even if they feel no negative effects.

Insulin Issues in Less Healthy Individuals

Unfortunately, though it is considered safe for most people who use it correctly, those who aren’t 100% healthy may experience insulin issues. Several studies have shown that MK 677 reduces participants’ insulin sensitivity whilst raising their fasting blood glucose and blood pressure levels.

Additionally, some users have reported swollen joints, numb/tingling skin, joint pain, water retention and lethargy as a result of taking Ibutamoren MK 677. These effects are usually caused by high dosages or by those with pre-existing medical conditions taking the supplement without consulting their doctor first.


With its ability to reverse catabolism, increase lean muscle mass, improve sleep quality and cognitive functions; there are plenty of reasons why so many bodybuilders are turning towards this compound as their go-to choice when trying to achieve their desired results from the gym.

Overall, when taken correctly MK 677 can be an incredibly effective way of boosting your HGH levels without any serious side effects – but it isn’t entirely risk free either.

If you are not 100% healthy then there may be some risks associated with taking this supplement so it’s always best to speak with your doctor first before beginning any supplementation plan involving Ibutamoren MK 677 – particularly if you have existing medical conditions which could make taking this product potentially dangerous for your health.

Ultimately though – done correctly – this product can be a great way to increase your natural growth hormone levels and reap all the benefits that come along with that!

cardarine review photos blog

Cardarine Review: Your Guide To GW-501516

Read our Cardarine review to understand what it is and why it seems to be shaking things up in the bodybuilding industry! What exactly is Cardarine and what are the benefits for muscle gain and fat loss?

Cardarine (also known as GW 501516) is a very interesting compound that you might have seen cropping up more and more in the bodybuilding and fitness community recently. It is often referred to as a SARM, mainly because it’s often found in the same category as other SARMs and often stacked alongside them. GW actually a PPAR-delta activator. In this article, we discuss what this means, how GW501516 works and why many bodybuilders are turning to Cardarine to help them gain muscle, lose fat, improve their physique and train harder in the gym.

What is Cardarine GW 501516?

Although some people call Cardarine a SARM, it is not actually a selective androgen receptor modulator. Cardarine is actually a PPAR-delta activator but it works in similar ways to a SARM and that’s why bodybuilders and gym trainees are attracted to it for muscle gain, strength gain and fat loss.

Cardarine was originally developed as a potential medical asset for prevention of tumours but it soon showed other benefits: it could help reduce body fat, control body weight, raise the metabolic rate, increase rates of muscle growth, and boost endurance. No wonder bodybuilders are keen to take a closer look!

Like all drugs of its type, Cardarine is banned by WADA and can not be used in professional sport or in any tested competitions – that includes drug tested bodybuilding contests.

Cardarine Review Alongside Trenbolone

Cardarine pairs well with Trenbolone because it can counteract a lot of the negative side effects such as night sweats, reduced endurance, loss of libido, shortness of breath, increased blood pressure and a poor balance between cholesterol levels (high LDL and low HDL).

Tren severely reduces your cardiovascular potential so using Cardarine alongside a Tren cycle makes a very noticeable improvement. Cardarine improves endurance levels and helps athletes to push further, recover faster and greatly improves their cardiovascular health.

Studies have shown that GW-501516 has a positive impact on the balance between HDL and LDL cholesterol which can offset the negative side effects of Trenbolone.

In one study, Cardarine increased HDL cholesterol and decreased triglycerides, insulin, and LDL cholesterol, which may altogether decrease the risk of heart disease.

A number of studies have also shown that Cardarine helps to lower high blood pressure.

Cardarine Review – Before & After Photos

Cardarine is one of the best compounds when it comes to boosting fat loss and increasing your endurance, energy and stamina. This PPAR modulator has been proven through valid research to have many health benefits but its performance benefits are its top advantages.

When it comes to fat loss, you’ll notice a major difference as well as an increase in vascularity as Cardarine promotes the burning of fat as a source of fuel. You’ll also see dramatically reduced recovery times after working out, and even a boost in your mood.

cardarine before and after
Cardarine 12-week cycle before and after photos
  • Incredible endurance enhancement
  • Dramatically reduced recovery time
  • Works from the first dose
  • Improves your mood
  • Enhances fat loss
  • Ideal for interval/cardio training
  • Stackable with other SARMs
  • Is NOT a stimulant and doesn’t increase heart-rate
  • Can be stacked with any other fat burners for maximum fat-burning potential

Read our blog to see more SARMs Before and After Photos.

How Does Cardarine Work?

Cardarine GW 501516 binds to the PPAR-delta nuclear receptors which are mostly in your muscles and stimulates some of the genes which govern how your body uses energy. By doing these two things, Cardarine can:

  • Help you burn more body fat – by preventing fatty acid chains from being formed, and therefore stopping your body from storing fat, so your system has to use stood fat for energy
  • Preserve existing muscle mass – when you are in an energy deficit and your body is forced to use fat for fuel, Cardarine can also protect muscle mass from catabolism
  • Faster recovery – Cardarine may increase the amount of oxygen which gets to your muscles, helping you recover from training sessions

Cardarine Review for Bodybuilding

1 Fat burning

Cardarine can help you burn more body fat by encouraging your body to use stored fat for fuel, by stimulating glucose, and by activating some of the genes involves in fat burning.

2 Bulking and cutting

Cardarine can be stacked with other SARMs to encourage fat loss, boost training performance, and help you maintain muscle mass when dieting – ideal for cutting and bulking cycles.

3 Brain health

Cardarine can improve blood flow to the brain, protecting brain vessels, boosting the growth of nerve cells, and reducing problematic inflammation.

4 Training endurance

Cardarine stimulates your body’s use of glucose for fuel, which means you can probably train longer and harder. More training = more muscle gain!

5 Muscle growth

Cardarine activates the PPAR-delta which boosts muscle fibres, gives you increased energy and means you can train for longer too.

6 Heart health

Cardarine may have a protective benefit for your blood vessels, reducing oxidative damage and plaque build-up, and increasing your levels of nitric oxide.

How To Dose Cardarine

Cardarine is kind of an all-rounder, you can use it for cutting or bulking cycles. It has a half life of 16 hours, so you will need to split your daily total dose into two doses. Start with 10mg/day (5mg twice per day), ideally with one dose 2-3 hours before you train. Run Cardarine for a maximum of 12 weeks, followed by a 6 week off-cycle break.

Can You Stack Cardarine?

A Cardarine Review wouldn’t be complete without some stack suggestions, so here they are! GW can be stacked with most other compounds. It mitigates fat-gain during bulking cycles, increases fat-loss during cutting cycles, and enhances endurance and performance all-round. Here are the most popular SARMs stacks:

Body-Recomposition Stack

  • Cardarine GW-501516
  • Ligandrol LGD-4033
  • Andarine S-4

Cutting Stack

  • Testolone RAD-140
  • Cardarine GW-501516
  • Stenabolic SR-9009
  • Andarine S-4

Strength Stack

  • Testolone RAD-140
  • Cardarine GW-501516
  • Andarine S-4

Bridging Stack

  • Andarine S-4
  • Ostarine MK-2866
  • Cardarine GW-501516
  • Stenabolic SR-9009

Endurance Stack

  • Cardarine GW-501516
  • Stenabolic SR-9009

Bulking Stack (with minimum fat-gain)

  • Cardarine GW-501516
  • Ostarine MK-2866
  • Ligandrol LGD-4033
  • Testolone RAD-140

Does Cardarine Have Any Side-Effects?

Like any compound, you should be sensible about using Cardarine. This includes looking out for side effects. Cardarine won’t suppress your natural hormone levels. It is always recommended to start off with lower doses and assess response and adaptation. If there is anything we haven’t covered in this Cardarine Review, see our Guide to Cardarine for more information.

andarine s4 benefits dosages blog

Andarine S4: Benefits, Dosages (Complete Guide)

Andarine (also known as S4) is a powerful selective androgen receptor modulator which can support muscle growth, mass, and density. This article will tell you everything you need to know about this increasingly favourable compound.

What Is Andarine S4?

Andarine S4 is a SARM (a selective androgen receptor modulator) sometimes also known as SARM S4. Like many SARMs, it has positive benefits on muscle mass, muscle gain and anabolism (helping you build muscle tissue and minimise muscle loss). But Andarine is stronger and more potent than many other SARMs.

Different SARMs have different levels of potency and this shows up in the results you can expect (and in what timeframe). What you need to know about Andarine is that it is pretty strong as SARMs go – so you can expect measurable results in a short time frame.

But there are some side effects to watch out for and we’ll detail those further in this article. However, Andarine is selective in which receptors it binds too, so side effects should be minimal if you are healthy and stick to recommended dosages.

Andarine works by binding to androgen receptors (in muscle tissue and bone tissue) which encourages your body to grow muscle. As a by-product of this, you’ll get stronger in the gym, you’ll be able to lift more and recover faster which will lead to yet more muscle gain.

Andarine S4 has been through human trials but no studies were published. There is some limited information which suggests that S-4 was described as the ideal SARM due to its single-day dosing, complete oral bioavailability and significant anabolic effects.

Understand The Benefits Of Andarine S4

Andarine can be used for bulking, cutting, body recomposition, strength gains, or competition prep but please remember you can not use Andarine – or any SARM – if you compete in drug-tested sport, including tested bodybuilding competitions because SARMs are banned by WADA.

  1. Dense muscle tissue – Andarine is renowned for giving that hard, dry look to muscles (which is why bodybuilder like it). Ideal if you want a full, pumped look
  2. Fat loss – Andarine seems to help with fat loss, possibly because it increases the metabolism of body fat and suppresses HSL (hormone-sensitive lipase)
  3. Strength gains – Andarine helps you build strength, and you may notice significant strength gains within a few weeks
  4. Dry gains – you shouldn’t experience water retention with SARM S4, meaning your muscle gains will look dry, not watery
  5. High bioavailability – meaning Andarine is absorbed into your system quickly, so it gets to work rapidly, even at low doses

You can see why S-4 is popular with bodybuilders, powerlifters, and other strength and power athletes. Just be careful with tested competition – like we’ve said, Andarine is banned (as are all SARMs) by WADA.

Are There Any Side Effects Of Andarine S4?

You should stay open to the possibility of side effects with any compound or medicine. Andarine is no different. Remember, SARMs were originally developed as potential medical solutions to physical issues, and most drugs have some potential side effects.

So what are the side effects of Andarine, and how can you minimise the chance of them happening? There are two key side effects to be aware of:

  • Night vision disturbance – some people report a kind of yellow tinge to their vision at night (probably because SARM S4 binds to receptors in the eyes). This shouldn’t be a problem – unless you work shifts, or need to drive or operate any kind of machinery at night. Most of these reports come from people taking high doses of Andarine.
  • Testosterone suppression – S4 does impact your natural test levels, and you will need to do a PCT (post cycle therapy) after using Andarine. Another way to keep this risk to a minimum is to run short cycles of 8 weeks maximum.

How To Use Andarine, Best Dosages

The best way to minimise the risks of any side effects is to get informed about how to use Andarine. This includes how much (dosages), how often (should you split the dose), and for how long (cycle length).

Andarine is a strong SARM, which means you can see good results even at low doses, so there is no need to take high doses – in fact, this just opens you up to more risk of side effects, for no need.

  • Start with 20mg-25mg Andarine a day.
  • Split your dose (whatever dose you take) into 2-3 doses per day. Take a dose in the morning, and one with your pre-training meal. If you are taking 1/3 dose, do this 4 hours after your previous dose.
  • After 2 weeks, assess your progress and results
  • If your progress has slowed down or stopped, increase the dose by 5mg per week for the rest of your cycle.
  • Do not keep increasing the dose all the while you are getting results – only increase it if your results stop.
  • Never go higher than 50mg/day (in fact, 35mg/day is a high dose).
  • Never take Andarine S4 for longer than 8 weeks (6-8 weeks is the least risky).

Andarine vs Other Popular SARMs

S4 is sometimes stacked with Ostarine (for cutting). Ostarine can be beneficial for building muscle mass and body recomposition. Andarine can also be stacked with Cardarine (for strength training), or with Ligandrol (for bulking). Remember, Andarine is already a strong SARM so there is no real need to stack.

Andarine S4 is a powerful SARM which is a kind of all-rounder, helping build muscle mass, burn body fat, and boost strength. But remember it is banned by WADA and can not be used for any tested sport or competition.

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