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Our fat loss blog posts feature the most popular SARMs and supplements for shedding that body fat.

SR9009 All Your Questions Answered (Video)
In Fat Lossby

SR9009 – Complete Guide to Stenabolic (Video)

SR9009, also known as Stenabolic, has gained notoriety in the bodybuilding community as “exercise in a bottle” – could this be the key to athletic performance and fat loss? Be sure to check out this video from Albina (SimplyFit London) to answer all your questions about this extraordinary compound.

What is SR9009?

SR9009, also known as Stenabolic, is a research drug that was developed by professor Thomas Burris of the Scripps Research Institute as an agonist of Rev-ErbA

This metabolic modulator has become increasingly popular in the fitness and bodybuilding communities. It works by binding to the Rev-erb protein, which plays a role in regulating the body’s internal clock. By doing so, SR9009 can activate certain genes that help regulate metabolism, leading to increased energy expenditure and fat loss. Additionally, it is believed to increase endurance and stamina, allowing athletes to train harder and longer.

Let’s take a closer look at this mysterious compound and its potential benefits for athletes.

How Does SR9009 Work?

SR9009 works by binding to the Rev-erb protein, which is responsible for regulating metabolism, lipid homeostasis, circadian rhythm (sleep/wake cycle), stress response, and other key functions of the human body. When SR-9009 binds to this protein, it activates certain genes that help regulate metabolism. This leads to increased energy expenditure, improved fat loss, increased endurance levels, and more efficient glucose uptake into muscle cells—all of which are beneficial for athletes who want to improve their performance.

What Are the Benefits of Taking SR9009?

When taken as directed (under medical supervision), there are several potential benefits associated with taking SR-9009:

  • Improved Endurance & Stamina – Because of its ability to stimulate energy expenditure and metabolic rate, taking SR- 9009 can lead to improved endurance levels during exercise or athletic activities. Additionally, those who take it may experience an increase in their stamina levels due to improved glucose uptake into muscle cells—allowing them to work out longer without feeling fatigued.
  • Increased Fat Loss – As mentioned previously, one of the primary ways that SR-900 9 increases energy expenditure is by stimulating fat loss—which can be beneficial for athletes looking to improve their physique or performance level.
  • Improved Muscle Growth & Strength – Due in part to its ability to improve glucose uptake into muscle cells, taking SR 900 9 can also lead to improved muscle growth & strength—which are essential for athletic performance improvement.

SR9009 FAQ

  1. What is SR9009?

SR9009, also known as Stenabolic, is a synthetic compound, known as a metabolic modulator, which was developed to study the circadian rhythm.

  1. How does SR-9009 work?

SR-9009 works by binding to the Rev-erb protein, which plays a role in regulating the body’s internal clock. By binding to this protein, SR-9009 can activate certain genes that help regulate metabolism, leading to increased energy expenditure and fat loss.

  1. What are the benefits of SR-9009?

The potential benefits of SR-9009 include increased energy expenditure, fat loss, improved endurance and stamina, and improved sleep quality.

  1. Is SR-9009 legal?

SR-9009 is currently not approved for human consumption but is not illegal for research purposes.

  1. Is SR-9009 a steroid?

No, SR-9009 is not a steroid.

  1. Can SR-9009 help with weight loss?

Yes, SR-9009 may help with weight loss by increasing energy expenditure and fat loss. It also has been shown to reduce the amount of cholesterol, triglycerides, insulin and free fatty acids.

  1. What are the potential side effects of SR-9009?

The potential side effects of SR-9009 may include nausea, insomnia, and headaches.

  1. How should SR-9009 be dosed?

The dosing recommendations for SR-9009 vary and are still being studied. However, most researchers will use 10-30mg per day.

  1. How long does it take for SR-9009 to work?

The timeline for SR-9009 to work is not well-established, as research on the compound is still ongoing. However, most research studies show that results begin to show within 1-2 weeks.

  1. Can SR-9009 improve endurance and stamina?

Yes, SR-9009 may improve endurance and stamina by increasing energy expenditure and fat loss.

  1. Can SR-9009 improve sleep quality?

There is some evidence to suggest that SR-9009 may improve sleep quality, but more research is needed to confirm this.

  1. Can SR-9009 cause liver damage?

The long-term effects of SR-9009 on liver function are not well-established, as research on the compound is still ongoing. However, no reports have suggested liver damage.

  1. Is SR-9009 safe for women to use?

Yes, SR9009 can be used by women and does not affect the sex hormones.

  1. Can SR-9009 be stacked with other supplements?

SR9009 is most often stacked alongside GW-501516 but can be used with any other SARM or supplement.

  1. Can SR-9009 be detected in drug tests?

Not most drug tests. However, SR9009 is banned by WADA and can not be used in professional sport or in any tested competitions – that includes drug tested bodybuilding contests.

  1. Is SR-9009 available in capsule form?

SR-9009 is available in various forms, including capsules and liquid.

  1. Can SR-9009 be purchased online?

Yes, SR-9009 can be purchased online from various retailers.

  1. Is SR-9009 a prescription drug?

No, SR-9009 is not a prescription drug.

  1. What is the recommended cycle length for SR-9009?

The recommended cycle length for SR-9009 varies and is still being studied. It is important to speak with a healthcare professional before using any performance-enhancing drug or supplement.

  1. Is SR-9009 effective for bodybuilding?

The effectiveness of SR-9009 for bodybuilding is not well-established, as research on the compound is still ongoing.

Conclusion

In conclusion, while further research is needed on the long term effects of using SARM compounds like SR 900 9 on humans; when used properly under medical supervision it appears that there are numerous potential benefits associated with using this compound – such as increased fat loss; improved endurance & stamina; as well as enhanced muscle growth & strength – all of which could be helpful for athletes looking for an edge over their competition. Just remember: always consult your doctor before starting any new supplement or medication program! With proper guidance from a professional healthcare provider you can decide if this type of product is right for you!

Are SARMs Legal in UK? 2023
In Fat Lossby

Glucose Disposal Agents: Hidden Secret to Fat Loss (2023)

Glucose disposal agents (GDAs) are supplements that are designed to help the body handle and use glucose more efficiently. They are becoming increasingly popular among fitness enthusiasts and those looking to lose fat and improve insulin sensitivity. In this article, we will explore the benefits of using glucose disposal agents for fat loss and improved insulin resistance.

What is Insulin Resistance?

First, let’s talk about insulin resistance. Insulin is a hormone that helps the body use and store glucose, which is the body’s primary source of energy. When the body becomes resistant to insulin, it can lead to a host of health problems, including weight gain, diabetes, and heart disease. Insulin resistance can occur when the body is exposed to high levels of glucose for prolonged periods of time, such as when consuming a diet high in refined carbohydrates.

Glucose Disposal Agents improve Insulin Sensitivity

Glucose Disposal Agents can help improve insulin sensitivity by increasing the body’s ability to use and store glucose. They do this by increasing the number of glucose transporters (GLUTs) in the cells, which are responsible for moving glucose into the cells. By increasing the number of GLUTs, GDAs help the body use glucose more efficiently and reduce the amount of glucose that is stored as fat.

How Glucose Disposal Agents can Aid Fat Loss

In addition to improving insulin sensitivity, Glucose Disposal Agents can also aid in fat loss. When the body is able to use glucose more efficiently, it is less likely to store it as fat. Furthermore, GDAs can also help reduce cravings for sugary foods, which can lead to overeating and weight gain.

Improve Endurance and Increase Muscle Mass with Glucose Disposal Agents

Another benefit of Glucose Disposal Agents is that they can help improve muscle mass and athletic performance. When the body is able to use glucose more efficiently, it can use it as a fuel source during exercise, rather than relying on stored fat. This can lead to improved endurance and increased muscle mass.

What is the Best GDA?

There are several different types of Glucose Disposal Agents available on the market, including berberine, alpha-lipoic acid, and cinnamon extract. Each of these supplements has been shown to improve insulin sensitivity and aid in fat loss. However, it is important to consult with a healthcare professional before starting any supplement regimen, as some GDAs can interact with certain medications and may not be suitable for certain individuals.

Ingredients to Look for in Glucose Disposal Agents

Chromium

Chromium is an essential mineral that may play a key role in glucose metabolism, weight loss and blood sugar control. Supplementing with its form called chromium picolinate has been demonstrated to lead to beneficial reductions in body fat and overall weight among some study participants.

Garcinia Cambogia

Garcinia Cambogia, a fruit found in tropical climates worldwide, has gained recent attention as an effective weight loss supplement. Its active ingredient – hydroxycitric acid (HCA) – is thought to aid shedding excess pounds by blocking the production of fat and suppressing hunger pangs. With dozens of studies backing its efficacy, this natural dietary product could be your key to success!

Glucomannan (from Konjac Root)

Glucomannan is a type of dietary fiber that comes from the root of the konjac plant. It is believed to help with weight loss by promoting feelings of fullness and reducing overall calorie intake. Glucomannan, being a water-soluble fiber, can help to slow down the digestion process, which may lead to a more gradual rise in blood sugar levels, which in turn can help to improve insulin sensitivity.

Bitter Melon Extract

Bitter Melon (Momordica charantia) has been used for centuries to promote wellness in various cultures around the world. Recent studies suggest that certain components found within the extract, such as charantin, momordin and polypeptide-p, could contribute to a healthier weight by suppressing appetite and reducing fat accumulation while promoting glucose uptake into individual cells. It is clear why this vegetable remains so popular!

Berbenne Hydrochloride

Berberine Hydrochloride is an alkaloid found in several plants, It is commonly used as an herbal supplement that has various benefits, such as to lower blood sugar, cholesterol, and blood pressure, to improve gut health, and to support the immune system.

Cinnamon Bark Extract

Cinnamon Bark Extract is an increasingly popular supplement, derived from the bark of cinnamon trees. It contains cinnamaldehyde – which gives it its unique taste and smell – as well as being studied for potential health benefits such as helping in weight loss and glucose metabolism related to insulin sensitivity.

White Kidney Bean Extract

White Kidney Bean Extract is a type of carbohydrate blocker that is thought to help with weight loss by inhibiting the enzyme alpha-amylase, which is responsible for breaking down carbohydrates into sugar. By inhibiting the enzyme, White Kidney Bean Extract may reduce the absorption of carbohydrates, and  improve insulin sensitivity and glucose metabolism.

Alpha Lipoic Acid

Alpha Lipoic Acid (ALA) is an antioxidant found in small amounts in certain foods. Supplementing with Alpha Lipoic Acid (ALA) may be an effective way to reduce both body weight and fat, according to research. A study published in the International Journal of Medical Sciences observed a statistically significant decrease in individuals’ body weight and fat when taking ALA supplements; additionally, it found that insulin sensitivity was improved as well as glucose metabolism.

Fenugreek Extract

Fenugreek, or Trigonella foenum-graecum, has a long history of traditional use for its medicinal properties. This herb is commonly consumed in supplement form with potential efficacy seen in aiding weight loss and moderating blood sugar levels as well as boosting insulin sensitivity. The active compounds found within the extract are believed to help reduce food cravings while slowing down carbohydrate digestion – both processes that can lead to reduced calorie intake and improved metabolism.

Myricetn

Myricetin is a natural compound found in plant-based foods with incredible potential. This powerful flavonoid contains potent antioxidant properties and has been studied for its positive influence on weight loss and insulin sensitivity in metabolic disease sufferers. Research indicates Myricetin can inhibit the formation of new fat cells, while also normalizing blood sugar levels by improving overall insulin sensitivity within the body – making it an essential player against obesity & diabetes!

Banaba Powder

Banaba powder, native to Southeast Asia, is quickly becoming a popular dietary supplement with potential health benefits. Rich in corosolic acid – a triterpenoid compound – Banaba has been linked to improved weight loss and insulin sensitivity when used as part of an overall healthy lifestyle. With the additional support from studies to back its promise up, this powerful plant may just be your key missing link for healthier living!

African Mango Extract

African Mango Extract is an exciting dietary supplement derived from the seeds of African Mangoes, a tree native to West Africa. High in fiber and healthy fats with potential benefits including weight loss and improved insulin sensitivity, this natural extract has been gaining attention for its significant health implications – recent studies have shown that it could aid individuals trying to reduce body fat or increase their insulin sensitivity.

The SLINX Glucose Disposal Agent

Pumping Iron SLINX (Glucose Disposal Agent) 60 Capsules – the most potent glucose disposal agent in the world. A Glucose Disposal Agent (GDA) and is essential for anyone who wants to enhance nutrient partitioning and stabilising blood glucose levels. Ultimately, this greatly improves your ability to gain lean muscle mass and reduce body fat levels.

  • Powerful Carb Blocker
  • Insulin Mimetic
  • Nutrient Partitioner
  • Supports Muscle Strength
  • Increases Muscle Fullness
  • Better Pumps in Gym
  • Greater Muscle Growth
  • Blocks Fat Storage

Ingredients in SLINX

Amount per Capsule:
Serving Size: 2 Capsules
Servings per Container: 30

  • Chromium 200mcg
  • Garcinia Cambogia 75mg
  • Glucomannan (from Konjac Root) 75mg
  • Bitter Melon Extract 300mg
  • Berbenne Hydrochloride 300mg
  • Cinnamon Bark Extract 200mg
  • White Kidney Bean Extract 250mg
  • Alpha Lipoic Acid 150mg
  • Fenugreek Extract 150mg
  • Myricetn 90mg
  • Banaba Powder 90mg
  • African Mango Extract 50mg
Pumping Iron SLINX (Glucose Disposal Agent) 60 Capsules
Pumping Iron SLINX (Glucose Disposal Agent) 

 

Conclusion

In conclusion, glucose disposal agents are supplements that can help improve insulin sensitivity and aid in fat loss. By increasing the number of glucose transporters in the cells, GDAs help the body use glucose more efficiently and reduce the amount of glucose that is stored as fat. They can also help reduce cravings for sugary foods, improve muscle mass and athletic performance. However, it is important to consult with a healthcare professional before starting any supplement regimen.

10 Surprising Benefits of MK-677 (Ibutamoren): Side Effects, Dosage, Timing (2023)
In Fat Loss, SARMs, Supplementsby

10 Surprising Benefits of MK-677: Side Effects, Dosage Review (2023)

10 Surprising Benefits of MK-677 – here is the low down with full review of the possible side effects, correct dosages and timing.

For serious athletes looking to optimise performance, MK 677 may be the answer. This popular product is a growth hormone secretagogue with powerful effects on one’s IGF-1 and GH levels – two hormones crucial for building strong muscles. Forget SARMs; you need this “secret” agent if you’re ready to take your bodybuilding game up a notch!

What is MK-677?

MK-677, also known as Ibutamoren, is a powerful growth hormone secretagogue that can help boost muscle tissue development. It has gained popularity in recent years amongst bodybuilders and gym fans for its natural ability to aid in the production of growth hormones without interfering with other biological processes.

MK-677 has been clinically studied and proven to be effective at assisting with hormone deficiencies such as reduced bone density, while at the same time providing short-term anabolic effects.  Additionally, it can also be used as a nootropic agent (a drug or supplement used to improve cognitive functioning), helping users with improved sleep and cognitive function.

How does MK-677 Work?

MK-677 works by binding to receptors in the brain that are responsible for releasing hormones like Growth Hormone (GH) and Insulin Like Growth Factor 1 (IGF-1). By doing this, it increases the body’s natural release of these hormones which help to promote healthy fat loss and muscle gain.

For those looking to build muscle or lose weight, this can prove extremely beneficial since GH helps stimulate protein synthesis and IGF-1 helps promote cell growth in muscles; leading to improved athletic performance.

Additionally, since it does not interfere with other biological processes or cause testosterone suppression – unlike other steroids – MK 677 is considered safe for long term use.

MK-677 Dosage and Timing

When taking MK 677, its 24-hour half life should be considered carefully. With an initial spike in growth hormone levels, you may find yourself feeling lethargic and drowsy further down the line. Our suggestion? Split your dose into two or take it all before bed – that way you can power through the day without sacrificing a good night’s rest!

Pumping Iron Ibutamoren (MK-677) 10mg x 60 Capsules
Pumping Iron Ibutamoren (MK-677) 10mg x 60

 

Read on to see the 10 Surprising Benefits of MK-677 making it the best-selling supplement today.

10 Surprising Benefits of MK-677

MK-677 has been coined the ‘fountain of youth’ – and rightfully so! This powerful compound not only aids in cultivating muscle mass and muscular strength; it can also promote overall wellbeing and cognitive function – transforming your body from the inside out. Here are 10 surprising benefits of MK-677:

1. Building Lean Muscle Mass

MK 677 has been suggested to be a powerful stimulant for muscle growth. Studies suggest it can trigger the production of two hormones which act in synergy – growth hormone and IGF-1 from your pituitary gland and liver respectively. This action could lead to an increase in strength, improved recovery time as well as positive changes on body composition (6-8lbs of extra lean mass over 6- 8 weeks based on oral doses).

A study conducted with 24 obese men revealed impressive results such as increased basal metabolic rate upon taking MK677 twice daily for 2 months.

2. Prevents Muscle Catabolism

An exciting study recently revealed that MK 677, a treatment option for reversing muscle wasting and protein loss, brought about remarkable improvements in elderly patients with hip fractures. Even more enthralling was the fact it already demonstrated success when tested on 8 food-deprived volunteers during an intensive double blind control trial – showing great promise as a viable solution to improve physical health.

3. Increases Fat Loss

Growth hormones are probably the only hormone which can help you to burn both visceral AND subcutaneous fat whilst helping you to build up lean muscle mass.

4. Improves Bone Density

Ibutamoren has shown promising evidence in the fight against bone-related conditions. It works by firstly reducing and then increasing turnover rate of bones over a period of 12 months, helping to strengthen them overall.

Studies have seen positive results when taken by obese men as well as elderly participants aged 65 years or more; all showing improved bone health and density – making it an ideal choice for treatment such as osteoporosis. Women too can benefit from this revolutionary new supplement with clinical studies reporting stronger mineral densities post-menopausal women taking MK 677 supplements!

5. Promotes Quality of Sleep

Get a good night’s sleep and gain strength even faster with MK 677, an effective nootropic that may improve both the length and quality of your REM cycle. With its neuroprotective properties supporting heightened cognitive function, take advantage of this supplement for not only better rest but improved health too!

6. Improves Hair, Skin and Nails

MK-677 can do wonders for your skin and hair – even in low doses! Studies have shown that GH has the power to revitalise your complexion whilst also strengthening the hair, skin and nails… giving you a healthier glow.

7. Promotes GH Longevity

After reaching adulthood, our bodies naturally produce less Growth Hormone (GH). To combat this shrinkage of GH levels in elderly men, researchers put 65 participants on a daily dose regimen of MK-677 – the results were staggering. These brave volunteers experienced an increase to their IGF-1 and GH numbers after only a month!

8. Improves Brain Function

MK-677 has the potential to unleash your full cognitive potential. Studies have shown that its two primary functions can drastically improve memory and learning, increase IGF-1 levels, as well as facilitate deep REM sleep – essential for optimal brain health. Take the steps towards better mental power today!

9. Prevent Growth Hormone Deficiency in Children

Studies have demonstrated that MK-677 can effectively boost key hormones in children with hormone deficiencies.

It has the potential to prevent growth issues without interfering with other important bodily functions like insulin, cortisol and thyrotropin production; making it a great treatment option for young people struggling to grow.

However, adults may not be so lucky as research found elevated levels of glucose or insulin when utilising this therapy – meaning further caution is advised before use by those over 18 years old.

10. Speeds up Recovery, Healing and Injury Repair

MK-677 promotes rapid recovery and injury repair by boosting Growth Hormone (GH) levels. This helps rebuild damaged tissues quickly, allowing athletes to get back in the game sooner than expected!

MK-677 Side Effects

MK 677 has become a popular supplement for bodybuilders, gym fanatics, and fitness buffs alike. In theory, it sounds like the perfect supplement – no testosterone suppression, no aromatization, nothing. But is MK 677 entirely safe? Let’s take a look at what you need to know about side effects and dosages before deciding if this is the right supplement for you.

Possible Side Effects of High Dosage

In completely healthy individuals, MK 677 is considered safe. The only possible side effects you may experience are muscle cramps, increased appetite and edema; these usually only crop up when you’ve taken too high a dosage of Ibutamoren. They will naturally disappear once you stop taking MK-677.

Side Effects in Healthy Individuals

When taken in recommended doses (between 10mg-25mg per day), Ibutamoren should be relatively free of side effects for healthy adults who are looking to boost their HGH levels without resorting to injections or other more risky methods such as steroids or growth hormone stimulants.

It should be noted that women tend to require smaller amounts than men due to their lower tolerance level; they should start with 5mg per day and gradually work up from there – never exceeding 25mg per day even if they feel no negative effects.

Insulin Issues in Less Healthy Individuals

Unfortunately, though it is considered safe for most people who use it correctly, those who aren’t 100% healthy may experience insulin issues. Several studies have shown that MK 677 reduces participants’ insulin sensitivity whilst raising their fasting blood glucose and blood pressure levels.

Additionally, some users have reported swollen joints, numb/tingling skin, joint pain, water retention and lethargy as a result of taking Ibutamoren MK 677. These effects are usually caused by high dosages or by those with pre-existing medical conditions taking the supplement without consulting their doctor first.

Conclusion

With its ability to reverse catabolism, increase lean muscle mass, improve sleep quality and cognitive functions; there are plenty of reasons why so many bodybuilders are turning towards this compound as their go-to choice when trying to achieve their desired results from the gym.

Overall, when taken correctly MK 677 can be an incredibly effective way of boosting your HGH levels without any serious side effects – but it isn’t entirely risk free either.

If you are not 100% healthy then there may be some risks associated with taking this supplement so it’s always best to speak with your doctor first before beginning any supplementation plan involving Ibutamoren MK 677 – particularly if you have existing medical conditions which could make taking this product potentially dangerous for your health.

Ultimately though – done correctly – this product can be a great way to increase your natural growth hormone levels and reap all the benefits that come along with that!

Best SARMs Stack for Cutting
In Fat Loss, SARMsby

Best SARMs Stack for Cutting (Updated 2023)

SARMs are getting increasingly more popular amongst bodybuilders, competitors and athletes, so one of the most common questions we get is to recommend the best SARMs stack for cutting. It’s not surprising when you consider that these compounds can help build muscle, give a denser, harder look to muscle and help burn body fat beyond our natural potential.

That’s the holy grail – adding mass and not losing it again when you diet! Not to mention, to speed up the process of losing body fat and revealing those chiselled abs!

Which are the best SARMs for fat loss? Here’s our take on it…

What Are SARMs & How Do They Work For Dieting?

SARMs are “selective androgen receptor modulators”, compounds which selectively bind to androgen receptors in the body’s tissues to help manipulate our natural hormone levels. Androgens are hormones which signal the body to make changes – like the way testosterone signals the body to grow.

By binding to some of the receptors which receive these hormonal messages, SARMs can specifically boost some of those signals. The key here is in the “selective” part of the name. SARMs don’t bind to every receptor (unlike anabolic hormones, which do). They only bind to receptors in bone tissue and muscle tissue. This selective nature means you get more specific in what you want the SARM to do, and you can avoid a lot of the side effects associated with steroids.

Most SARMs were initially developed as a possible way to create certain medical conditions, specifically those related to loss of bone density, muscle mass, and strength. They caught the eye of researchers because they were able to bind only to the affected tissues, and not to anything else like internal organs.

SARMs can be taken as orals which makes them easier and more user-friendly than anabolics.

But what about using SARMs for fat loss? In this article, we will look at how to use SARMs for cutting (fat loss dieting) whether you want to do that for your health, your appearance, or as a bodybuilder.

The Best SARMs for Cutting

In order to put together the best SARMs stack for cutting, we’ll take a look at the different SARMs that are best for fat loss, and the reason why they make a good choice for your dieting phase.

Each of the different compounds below has superb fat-shedding qualities and these are often interchanged depending on the preferences of the individual user. In short, the best SARMs stack for cutting is the one that works for you! See which compounds fit your preferences and do your research – that is always the best way.

Andarine S4

Andarine, or S4, is a strong and potent SARM which is thought to increase fat oxidation and reduce lipoprotein lipase which is linked to fat accumulation in the body. Initially developed to combat conditions such as osteoporosis and muscle wastage, S-4 is one of the most researched SARMs which is always a positive aspect.

Andarine also helps increase muscle mass and strength. Even low doses of Andarine can help you maintain all your gains when you go into a calorie deficit to get lean. All in all, a good choice for cutting or body recomposition.

Best dose: start at 25mg/day split into 2-3 doses (4-6 hours apart), never go higher than 50mg/day and keep cycles to an 8-12 week maximum.

Ostarine

Ostarine MK 2866 really helps boost muscle gain because it increases the body’s levels of nitrogen and protein. This makes it a good choice for protecting muscle mass when you diet, avoiding that stringy, over-dieted look.

LGD-3303 (Not LGD-4033!)

A quick update here: LGD-3303 has now been patented by pharmaceutical company Ligand Pharmaceuticals Incorporated and is no longer available on the market.

LGD-3303 is a potent and highly selective androgen receptor full agonist in skeletal muscle, a classic target tissue for androgen action. By comparison, in the prostate and sebaceous glands, the compound is a weak partial agonist. The sparing of these non-target tissues by effective, pharmacologic doses of LGD-3303 provides a novel and potentially safer treatment for osteoporosis.

Source: Ligand Pharmaceuticals Incorporated

Released September 17, 2007

Here’s where our recommendation on the best SARMs stack for cutting is different from any other you may have seen online. Most will recommend Ligandrol but we beg to differ. LGD-3303 is the leaner, dryer, fuller and more vascular successor of Ligandrol (LGD 4033). For that reason, it undoubtedly takes the throne.

Cardarine

Cardarine GW 501516 isn’t actually a SARM but a PPAR gamma receptor agonist that binds to PPARδ receptors instead of androgen receptors like a SARM normally would.

Cardarine supports healthy cholesterol levels and increases your basal metabolic rate, which helps your body to burn more energy (aka fat) even when at rest. You might also feel an energy boost, which definitely helps when you are dieting in a calorie deficit! Cardarine is a compound we stack with pretty much anything; this one’s a winner all-round… even when bulking to mitigate fat gain.

Stenabolic

Stenabolic SR 9009 is another on this list which isn’t actually a SARM (it’s a REV-ERB agonist) but it deserves a place on this list. As a REV-ERBα agonist, it can help manipulate certain functions relating to the metabolism, so you feel more energised, burn more stored fat, and get a boost to your metabolic rate even at rest. Stenabolic is also a compound we love to stack with pretty much anything.

MK-677

MK-677 is a growth hormone secretagogue and stacks well with virtually anything. It is a very versatile compound that can be used for both bulking or cutting, depending on the accompanying diet and training plan (increased calories will support bulking and reduced calorie intake supports fat loss).

Glucose Disposal Agents

Although Glucose Disposal Agents aren’t SARMs, they deserve a mention. Nutrient partitioning often gets forgotten about but is so effective when it comes to body composition. A glucose disposal agent decreases the amount of insulin secreted by the body when eating a high-carbohydrate meal and shuttles glucose into muscle cells instead of storing them in fat cells. This results in reduced fat gain and a potential increase in lean muscle gain.

The Best SARMs Stack for Cutting

As we’ve already pointed out, you can stack different SARMs to assist you during a cut and there are different ways to mix and match the compounds that work best for the individual.

One of the best SARMs stack for cutting we’ve researched is for the more advanced and experienced:

  • Andarine S-4 – 50mg per day, 25mg in the a.m. and 25mg 4-6 hours later
  • Ostarine MK-2866 – 20mg per day, dosed once a day in the a.m.
  • GW/SR (SR-9009/Cardarine Blend) – 1 capsule in the a.m, 1 capsule in the p.m.
  • MK-677 – 20mg per day, dosed once per day (can be reduced to 10mg if appetite increase is unmanageable).

5 Keys To Getting Shredded

Remember that there are several aspects to getting that lean, shredded look. Sure, you need to reduce your body fat. But you also want to increase muscle mass, and – crucially – retain as much muscle as possible even as you diet to lose fat. It’s a difficult task, but SARMs can make it much easier.

1 A calorie deficit

You need to be in a calorie deficit to lose body fat, it doesn’t matter what kind of diet you follow – a calorie deficit is crucial. This means making sure your total “calories out” are higher than your “calories in”

2 Sufficient protein intake

Eating enough protein will help you build muscle, maintain muscle, and it will help keep you feeling fuller (protein has the highest Thermic Effect Of Food of any macronutrient) which will help diet compliance

3 Training frequency

We now know that training frequency is the most important factor in muscle gain and muscle retention, ideally train each major muscle group every 72 hours

4 Load and volume

Within that training, you need to put enough load (weight) and volume (weight x sets x reps) through the muscles

5 Appetite and energy management

Get control of your appetite, eating habits, and your energy output to increase your success with getting super-lean and shredded!

What’s the Best PCT for SARMs?

Although PCT is a very subjective matter, it’s often recommended to run a PCT such as Pro PCT (6-OXO).

Pumping Iron Pro PCT (6-OXO)
Pumping Iron Pro PCT (6-OXO)

 

Pumping Iron Pro PCT (6-OXO) is an innovative, advanced solution for male athletes who use SARMs and prohormones. Formulated with a potent aromatase inhibitor – 6-OXO – this supplement can be used as both preventative care against estrogen related side effects while cycling or during post cycle therapy to aid in recovery. It should only be taken by experienced users of choose hormones and supplements due its powerful formulation; women are not advised to take it at all.

  • Strongest aromatase inhibitor on the market
  • Increases lean muscle mass
  • Reduces conversion of testosterone to estradiol
  • Supports muscle retention
  • Increases testosterone:estrogen ratio
  • Suitable for vegans (HMPC Veg Cap)

 

The Best Prohormones for Cutting
In Fat Loss, Prohormonesby

Best Prohormones for Cutting (Updated 2023)

The best prohormones for cutting and getting shredded are those that don’t cause water retention and provide the chiselled, well-defined physique throughout the cycle.

Getting lean and shredded is one of the most popular goals on the gym floor. Every guy wants to get super-lean at least once in his life. And when you decide to do it you’ll want to go all out. After all, there’s no point grinding through a diet and doing extra cardio if you’re only going to get mediocre results at the end of it.

If you’re planning your next cut, you might be wondering whether SARMs or prohormones could help you get that bit leaner than before…

The answer is yes, there are compounds out there that can help you burn more fat, get leaner and – crucially – hang on to muscle whilst you melt away fat.

What are the best prohormones for cutting? Let’s find out.

What Are Prohormones?

Pro hormones are different from SARMs and they are definitely not anabolic steroids either. Prohormones are really “pro-steroids”) because they act as precursors to anabolic growth hormones in your body, encouraging your body to churn out more of those muscle-building, fat burning, strength gaining hormones.

Are Prohormones Legal?

You need to do your research about the legality of prohormones (which is why you’re here!) In the USA, a lot of prohormones were banned under the 2014 Designer Anabolic Steroid Control Act of 2014 in the USA. That said, a few remain outside of this ban. These currently include:

  • 1-Androsterone (1-DHEA or 1-androstene-3b-ol-17-one)
  • 4-Androsterone (4-DHEA or 4-androstene-3b-ol-17-one)
  • 1,4-OHP
  • Epiandrosterone (Epi-Andro)
  • 6-Keto-progesterone

And do remember that all prohormones are banned by WADA, so if you are planning on doing any tested competitions – included natural or drug-free bodybuilding contest – you won’t be able to use prohormones at all.

How Do Prohormones Help You Get Leaner?

If you are thinking about using prohormones on your next cutting diet, you will want to know exactly how they would potentially help. The best prohormones for cutting and getting shredded are those that don’t cause water retention and provide the chiselled, well-defined physique throughout the entirety of the cycle.

As you know, there are a few factors that lead to some dropping body fat, retaining muscle and rocking that lean, full look.

1 Losing body fat.

The key to this is a calorie deficit, but anything that helps boost the metabolism and hang on to lean muscle will help. Prohormones can do both those things.

2 Energy output

The more energy you can burn (as long as you don’t overeat to compensate!) the more fat you’ll lose. Prohormones can give you an energy boost and training endurance.

3 Training intensity

You need to lift heavy and often to burn fat and keep muscle on in a diet. Prohormones give you the energy and drive that you need to train through a deficit.

4 Muscle retention

The more muscle tissue you can retain on a diet, the better you’ll look (and the healthier your metabolic rate will be). Prohormones can help you keep hold of more muscle.

Prohormones act as a precursor to the hormones testosterone and dihydrotestosterone, encouraging your endocrine (hormonal) system – including your pituitary and thyroid glands – to use this excess of anabolic hormones to build more muscle.

The Best Prohormones For Cutting

Here are the three best prohormones for cutting, producing lean/dry gains with no water retention:

  1. Pumping Iron Pro DMZ is a blend of methylstenbolone and dymethazine for extreme mass and strength gains. Expect dry, hard muscle gains, fast fat loss, amazing pumps and a full lean look to your physique.For advanced users only.
  2. Pumping Iron M-Tren gives amazingly dry, lean gains in muscle mass so you can expect at increasing strength and visible physique changes, no bloat, no water retention and full muscles. Great for a body recoup or cutting cycle.
  3. Pumping Iron S-DROL is the original. The legend – extreme gains in size, power, strength, harness, vascularity and fat loss.

When you’re supplementing with prohormones, it’s important that you use the right product depending on your goals. The best prohormones for cutting are considered ‘dry’ compounds.

Prohormones fall into two main categories; wet and dry. A ‘wet’ compound will cause you to retain water during the cycle and generally be bulkier, which aids muscle protein synthesis (these prohormones are usually more potent than the dry compounds). This is great if you’re bulking but not so much if you want visible abs.

The other options are ‘dry’ compounds. These compounds will cause you to shed water and will often increase muscle hardness and fullness, as well as density and vascularity.

Stacking Prohormones

You can stack prohormones or just get the blends such as the Pro-DMZ mentioned above which has done the lab work for you. Unless you are an advanced user, we don’t think it’s worth the risk of working out your own stack when you can buy a combined product that has already been created by experts.

When stacking prohormones, bear in mind that you do not need to run the products at full doses as you would if taken alone.

Prohormone Side Effects

You wouldn’t take any medication or drug without checking potential side effects, would you? So the same goes for prohormones.

Some people report increased blood pressure, acne, hair loss, liver stress, or reduced HDL cholesterol from prohormone use.

We think the best way to try and avoid any of this is by purchasing quality, trusted products (rather than trying to stack your own), always sticking to the dosage recommendations, never running a super-long cycle and always doing a PCT and natural testosterone booster afterwards to look after your health.

How To Take Prohormones For Dieting

If you buy prohormones from a trusted source, you’ll also be getting the best advice about doses and cycle length. Stick to this advice, don’t be a hero and just rely on the product to do its job.

Remember, even the best prohormones for cutting can’t help you lose fat if you aren’t also dieting. They’re not a magic pill (although they might feel like it!) so be sure you have your diet in check, your training is intense and regular and you stay active with a good step count or extra cardio if you have a sedentary lifestyle.

What’s The Best Cycle Support for Prohormones?

As with any pro-hormone, long term use of prohormones could have adverse effects on your liver, so you should use cycle support such as Pumping Iron High Strength TUDCA.

The Pumping Iron TUDCA is a state of the art liver detox product that works perfectly as a detox product alone or alongside a prohormone cycle. A crucial aspect to successfully running your prohormone cycle is preserving your best health, so you can feel well in your body and revitalised after your post cycle therapy to enjoy your new-found strength and results in the long term.

What’s the Best PCT for Prohormones?

After taking pro hormones you should run a PCT such as Pro PCT (6-OXO).

Pumping Iron Pro PCT (6-OXO) is an advanced SARMs and prohormone PCT that contains 6-OXO, a potent aromatase inhibitor which should only be used by experienced users of SARMs and prohormones. This supplement is intended for male athletes only and shouldn’t be used by women. PRO PCT can be used to prevent estrogen related side effects on-cycle as well as a powerful recovery agent for post cycle therapy (PCT).

  • Strongest aromatase inhibitor on the market
  • Increases lean muscle mass
  • Reduces conversion of testosterone to estradiol
  • Supports muscle retention
  • Increases testosterone:estrogen ratio
  • Suitable for vegans (HMPC Veg Cap)
Pumping Iron Pro PCT (6-OXO)
Pumping Iron Pro PCT (6-OXO)
Stenabolic SR9009 - The Secret Fat Loss Wonder Drug
In Fat Loss, SARMsby

Stenabolic SR9009 – The Secret Fat Loss Wonder Drug (Updated 2023)

We write about SARMs at Pumping Iron Store but this is something a little different. Although you will often hear Stenabolic SR9009 talked about in the same conversation as SARMs, it is not, in fact, a SARM. This article will tell you about Stenabolic, why it was developed, what it is, the benefits and side effects and what to expect.

Although Stenabolic SR9009 was developed to study the circadian rhythm, studies have shown this drug to improve the overall health and quality of life of anyone who uses it. Dubbed as ‘exercise in a bottle’, research on Stenabolic shows that it can help to lose weight, decrease cholesterol, inflammation and even anxiety.

What Is Stenabolic SR9009?

As we have briefly mentioned, Stenabolic is not a SARM. It is a compound that was developed by researchers in a bid to treat or manage medical conditions. Stenabolic is a REV-ERB (specifically a REV-ERBα antagonist) which means it impacts the metabolism, including the circadian rhythm. It’s pretty complicated to explain, but here’s our best layman’s version:

Your body’s circadian rhythm is a pattern your system cycles through every 24 hours. Experts think it is linked to sunrise and sunset. It governs things like sleep, waking, energy levels, and hunger. Part of the cycle that keeps your circadian rhythm going involves “switching” genes on and off throughout the 24-hour cycle.

History of SR-9009

Stenabolic was initially developed for its effects on the circadian rhythm and was found to improve mood, control anxiety, reduce inflammation, and even have a positive impact on weight gain. Sounds good for bodybuilding, right?

Stenabolic was also found to increase the activity of REV-ERB nuclear hormone receptors, and this boosts the bioavailability of nutrients in your body. For us as bodybuilders, this means better nutrient uptake and more of the nutrients we eat gets to our muscle tissue.

One thing you must consider about SR9009 is that there is no human research on it. There’s plenty of research from animal studies (especially mice studies) but none on human subjects. There is plenty of anecdotal evidence and feedback from guys who use it to augment their training. So be sure to go into this with your eyes open and full awareness of the lack of human research.

How Does Stenabolic SR9009 Work?

The processes behind SR9009 are pretty complicated and well beyond a short article here. If you’re the deep-dive research kind of reader, take a look at this paper published in Nature Reviews Drug Discovery in 2014 or this 2016 paper published in the International Journal of Molecular Sciences.

SR9009 has a significant impact on REV-ERBA, which impacts circadian control and has knock-on effects on the immune system, sleeping patterns, energy production, and general activity.

Activation of Rev-ErbA-α by SR9009 increases exercise capacity by increasing mitochondria counts in skeletal muscle.

REV-ERB is particularly influential in the tissues of the muscles, body fat, and liver. This suggests it could help boost fat burning, “switching off” the genes which store fat and increasing the number of mitochondria in the muscles.

OK, that’s a lot of scientific talk (and a couple of papers for you to look at). But what about the real-life stuff – how does SR 9009 benefit bodybuilders and people who want to get big, ripped, and lean?

Benefits of Stenabolic SR9009

Stenabolic SR9009 has been shown to have several potential benefits, including increased endurance and stamina, improved metabolism and fat burning, and enhanced recovery after exercise. It may also have neuroprotective and anti-inflammatory effects.

  • Increases oxygen consumption
  • Prevents the creation of new fat cells in the liver
  • Increases the number of mitochondria in the muscle cells
  • Increases glucose and lipid metabolism
  • Decreases triglyceride levels in the blood
  • Reduces cholesterol breakdown in the liver
  • Promotes fat loss through glucose consumption
  • Regulates blood sugar levels
  • SR9009 has even been used to treat type-2 Diabetes
  • Delays the ageing process
  • Reduces inflammation
  • Decreases anxiety

1 Weight loss & fat loss

SR9009 has been shown to increase weight loss even without altering dietary intake. It has also been shown to reduce amounts of free fatty acids, triglycerides, and cholesterol. It could be great as a fat burner when you’re dieting or trying to get rid of that last bit of body fat.

2 Mood & energy

SR9009 is thought to be able to affect sleep patterns, which is beneficial to recovery and general health. It has been shown to increase energy levels and could even be used to increase wakefulness. Some studies also suggest SR 9009 could reduce anxiety.

3 Endurance

SR9009 has been shown to increase the total amount of mitochondria, which has a direct impact on endurance levels for physical activity. More endurance = more training = more gains.

4 Reduced inflammation

Inflammation can pose a big problem for bodybuilders who train hard, and Stenabolic SR9009 may be able to tackle this issue (by reducing TNF alpha in the body – these cells are a key player in systemic inflammation).

Does Stenabolic Have Side Effects?

Since Stenabolic SR9009 is a research chemical and has not been extensively studied in humans, the potential side effects are not fully known. However, some users have reported side effects such as headache, nausea, and insomnia.

Stenabolic has shown no liver toxicity.

However, we do know that SR9009 doesn’t impact the body’s natural hormone levels so you won’t need to run a PCT if you use Stenabolic.

Is Stenabolic SR9009 legal?

Stenabolic SR9009 is not approved for human consumption, however it is legal to sell and purchase for research purposes.

Is Stenabolic SR9009 a Steroid?

Stenabolic SR9009 is not a steroid, but it is often grouped together with other performance-enhancing compounds due to its potential benefits for athletes and bodybuilders. It is important to note that using any performance-enhancing compound comes with potential risks and side effects.

Best Dosage & Cycle Length for Stenabolic

Stenabolic has a half-life of 4 hours so you’ll need to split your total daily dose into 2-3 doses per day. So, if you’re taking 20mg/day, take 5mg every 4 hours (say, at 8 am, 12 pm, 4 pm, 8 pm).

Start at 10mg-20mg/day (maximum) and increase only to 30mg if you need to.

Most will run Stenabolic SR9009 cycles of 8-12 weeks, followed by the same time off.

How to Use Stenabolic SR9009

Stenabolic SR9009 is typically taken orally in capsule form. The recommended dosage is usually between 20-30mg per day, although dosages may vary depending on individual needs and goals.

Can Stenabolic SR9009 be Stacked with other Supplements

Stenabolic SR9009 can be stacked with other supplements or compounds, but it is important to do so carefully and with the guidance of a healthcare professional. Some users have reported success in stacking SR9009 with other SARMs or compounds such as Cardarine, Ostarine, and Ligandrol.

Does SR-9009 Require a PCT?

Stenabolic (SR-9009) is not suppressive and does not generally require a PCT.

cardarine review photos blog
In SARMs, Fat Lossby

Cardarine Review: Your Guide To GW-501516

Read our Cardarine review to understand what it is and why it seems to be shaking things up in the bodybuilding industry! What exactly is Cardarine and what are the benefits for muscle gain and fat loss?

Cardarine (also known as GW 501516) is a very interesting compound that you might have seen cropping up more and more in the bodybuilding and fitness community recently. It is often referred to as a SARM, mainly because it’s often found in the same category as other SARMs and often stacked alongside them. GW actually a PPAR-delta activator. In this article, we discuss what this means, how GW501516 works and why many bodybuilders are turning to Cardarine to help them gain muscle, lose fat, improve their physique and train harder in the gym.

What is Cardarine GW 501516?

Although some people call Cardarine a SARM, it is not actually a selective androgen receptor modulator. Cardarine is actually a PPAR-delta activator but it works in similar ways to a SARM and that’s why bodybuilders and gym trainees are attracted to it for muscle gain, strength gain and fat loss.

Cardarine was originally developed as a potential medical asset for prevention of tumours but it soon showed other benefits: it could help reduce body fat, control body weight, raise the metabolic rate, increase rates of muscle growth, and boost endurance. No wonder bodybuilders are keen to take a closer look!

Like all drugs of its type, Cardarine is banned by WADA and can not be used in professional sport or in any tested competitions – that includes drug tested bodybuilding contests.

Cardarine Review Alongside Trenbolone

Cardarine pairs well with Trenbolone because it can counteract a lot of the negative side effects such as night sweats, reduced endurance, loss of libido, shortness of breath, increased blood pressure and a poor balance between cholesterol levels (high LDL and low HDL).

Tren severely reduces your cardiovascular potential so using Cardarine alongside a Tren cycle makes a very noticeable improvement. Cardarine improves endurance levels and helps athletes to push further, recover faster and greatly improves their cardiovascular health.

Studies have shown that GW-501516 has a positive impact on the balance between HDL and LDL cholesterol which can offset the negative side effects of Trenbolone.

In one study, Cardarine increased HDL cholesterol and decreased triglycerides, insulin, and LDL cholesterol, which may altogether decrease the risk of heart disease.

A number of studies have also shown that Cardarine helps to lower high blood pressure.

Cardarine Review – Before & After Photos

Cardarine is one of the best compounds when it comes to boosting fat loss and increasing your endurance, energy and stamina. This PPAR modulator has been proven through valid research to have many health benefits but its performance benefits are its top advantages.

When it comes to fat loss, you’ll notice a major difference as well as an increase in vascularity as Cardarine promotes the burning of fat as a source of fuel. You’ll also see dramatically reduced recovery times after working out, and even a boost in your mood.

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Cardarine 12-week cycle before and after photos
  • Incredible endurance enhancement
  • Dramatically reduced recovery time
  • Works from the first dose
  • Improves your mood
  • Enhances fat loss
  • Ideal for interval/cardio training
  • Stackable with other SARMs
  • Is NOT a stimulant and doesn’t increase heart-rate
  • Can be stacked with any other fat burners for maximum fat-burning potential

Read our blog to see more SARMs Before and After Photos.

How Does Cardarine Work?

Cardarine GW 501516 binds to the PPAR-delta nuclear receptors which are mostly in your muscles and stimulates some of the genes which govern how your body uses energy. By doing these two things, Cardarine can:

  • Help you burn more body fat – by preventing fatty acid chains from being formed, and therefore stopping your body from storing fat, so your system has to use stood fat for energy
  • Preserve existing muscle mass – when you are in an energy deficit and your body is forced to use fat for fuel, Cardarine can also protect muscle mass from catabolism
  • Faster recovery – Cardarine may increase the amount of oxygen which gets to your muscles, helping you recover from training sessions

Cardarine Review for Bodybuilding

1 Fat burning

Cardarine can help you burn more body fat by encouraging your body to use stored fat for fuel, by stimulating glucose, and by activating some of the genes involves in fat burning.

2 Bulking and cutting

Cardarine can be stacked with other SARMs to encourage fat loss, boost training performance, and help you maintain muscle mass when dieting – ideal for cutting and bulking cycles.

3 Brain health

Cardarine can improve blood flow to the brain, protecting brain vessels, boosting the growth of nerve cells, and reducing problematic inflammation.

4 Training endurance

Cardarine stimulates your body’s use of glucose for fuel, which means you can probably train longer and harder. More training = more muscle gain!

5 Muscle growth

Cardarine activates the PPAR-delta which boosts muscle fibres, gives you increased energy and means you can train for longer too.

6 Heart health

Cardarine may have a protective benefit for your blood vessels, reducing oxidative damage and plaque build-up, and increasing your levels of nitric oxide.

How To Dose Cardarine

Cardarine is kind of an all-rounder, you can use it for cutting or bulking cycles. It has a half life of 16 hours, so you will need to split your daily total dose into two doses. Start with 10mg/day (5mg twice per day), ideally with one dose 2-3 hours before you train. Run Cardarine for a maximum of 12 weeks, followed by a 6 week off-cycle break.

Can You Stack Cardarine?

A Cardarine Review wouldn’t be complete without some stack suggestions, so here they are! GW can be stacked with most other compounds. It mitigates fat-gain during bulking cycles, increases fat-loss during cutting cycles, and enhances endurance and performance all-round. Here are the most popular SARMs stacks:

Body-Recomposition Stack

  • Cardarine GW-501516
  • Ligandrol LGD-4033
  • Andarine S-4

Cutting Stack

  • Testolone RAD-140
  • Cardarine GW-501516
  • Stenabolic SR-9009
  • Andarine S-4

Strength Stack

  • Testolone RAD-140
  • Cardarine GW-501516
  • Andarine S-4

Bridging Stack

  • Andarine S-4
  • Ostarine MK-2866
  • Cardarine GW-501516
  • Stenabolic SR-9009

Endurance Stack

  • Cardarine GW-501516
  • Stenabolic SR-9009

Bulking Stack (with minimum fat-gain)

  • Cardarine GW-501516
  • Ostarine MK-2866
  • Ligandrol LGD-4033
  • Testolone RAD-140

Does Cardarine Have Any Side-Effects?

Like any compound, you should be sensible about using Cardarine. This includes looking out for side effects. Cardarine won’t suppress your natural hormone levels. It is always recommended to start off with lower doses and assess response and adaptation. If there is anything we haven’t covered in this Cardarine Review, see our Guide to Cardarine for more information.

andarine s4 benefits dosages blog
In Fat Loss, SARMsby

Andarine S4: Benefits, Dosages (Complete Guide)

Andarine (also known as S4) is a powerful selective androgen receptor modulator which can support muscle growth, mass, and density. This article will tell you everything you need to know about this increasingly favourable compound.

What Is Andarine S4?

Andarine S4 is a SARM (a selective androgen receptor modulator) sometimes also known as SARM S4. Like many SARMs, it has positive benefits on muscle mass, muscle gain and anabolism (helping you build muscle tissue and minimise muscle loss). But Andarine is stronger and more potent than many other SARMs.

Different SARMs have different levels of potency and this shows up in the results you can expect (and in what timeframe). What you need to know about Andarine is that it is pretty strong as SARMs go – so you can expect measurable results in a short time frame.

But there are some side effects to watch out for and we’ll detail those further in this article. However, Andarine is selective in which receptors it binds too, so side effects should be minimal if you are healthy and stick to recommended dosages.

Andarine works by binding to androgen receptors (in muscle tissue and bone tissue) which encourages your body to grow muscle. As a by-product of this, you’ll get stronger in the gym, you’ll be able to lift more and recover faster which will lead to yet more muscle gain.

Andarine S4 has been through human trials but no studies were published. There is some limited information which suggests that S-4 was described as the ideal SARM due to its single-day dosing, complete oral bioavailability and significant anabolic effects.

Understand The Benefits Of Andarine S4

Andarine can be used for bulking, cutting, body recomposition, strength gains, or competition prep but please remember you can not use Andarine – or any SARM – if you compete in drug-tested sport, including tested bodybuilding competitions because SARMs are banned by WADA.

  1. Dense muscle tissue – Andarine is renowned for giving that hard, dry look to muscles (which is why bodybuilder like it). Ideal if you want a full, pumped look
  2. Fat loss – Andarine seems to help with fat loss, possibly because it increases the metabolism of body fat and suppresses HSL (hormone-sensitive lipase)
  3. Strength gains – Andarine helps you build strength, and you may notice significant strength gains within a few weeks
  4. Dry gains – you shouldn’t experience water retention with SARM S4, meaning your muscle gains will look dry, not watery
  5. High bioavailability – meaning Andarine is absorbed into your system quickly, so it gets to work rapidly, even at low doses

You can see why S-4 is popular with bodybuilders, powerlifters, and other strength and power athletes. Just be careful with tested competition – like we’ve said, Andarine is banned (as are all SARMs) by WADA.

Are There Any Side Effects Of Andarine S4?

You should stay open to the possibility of side effects with any compound or medicine. Andarine is no different. Remember, SARMs were originally developed as potential medical solutions to physical issues, and most drugs have some potential side effects.

So what are the side effects of Andarine, and how can you minimise the chance of them happening? There are two key side effects to be aware of:

  • Night vision disturbance – some people report a kind of yellow tinge to their vision at night (probably because SARM S4 binds to receptors in the eyes). This shouldn’t be a problem – unless you work shifts, or need to drive or operate any kind of machinery at night. Most of these reports come from people taking high doses of Andarine.
  • Testosterone suppression – S4 does impact your natural test levels, and you will need to do a PCT (post cycle therapy) after using Andarine. Another way to keep this risk to a minimum is to run short cycles of 8 weeks maximum.

How To Use Andarine, Best Dosages

The best way to minimise the risks of any side effects is to get informed about how to use Andarine. This includes how much (dosages), how often (should you split the dose), and for how long (cycle length).

Andarine is a strong SARM, which means you can see good results even at low doses, so there is no need to take high doses – in fact, this just opens you up to more risk of side effects, for no need.

  • Start with 20mg-25mg Andarine a day.
  • Split your dose (whatever dose you take) into 2-3 doses per day. Take a dose in the morning, and one with your pre-training meal. If you are taking 1/3 dose, do this 4 hours after your previous dose.
  • After 2 weeks, assess your progress and results
  • If your progress has slowed down or stopped, increase the dose by 5mg per week for the rest of your cycle.
  • Do not keep increasing the dose all the while you are getting results – only increase it if your results stop.
  • Never go higher than 50mg/day (in fact, 35mg/day is a high dose).
  • Never take Andarine S4 for longer than 8 weeks (6-8 weeks is the least risky).

Andarine vs Other Popular SARMs

S4 is sometimes stacked with Ostarine (for cutting). Ostarine can be beneficial for building muscle mass and body recomposition. Andarine can also be stacked with Cardarine (for strength training), or with Ligandrol (for bulking). Remember, Andarine is already a strong SARM so there is no real need to stack.

Andarine S4 is a powerful SARM which is a kind of all-rounder, helping build muscle mass, burn body fat, and boost strength. But remember it is banned by WADA and can not be used for any tested sport or competition.

MK-677 Before and After Photos: Impressive Results
In Fat Loss, SARMsby

MK-677 Before and After Photos

As you might know, MK-677 is one of the most interesting compounds currently being used by athletes and bodybuilders, so we’ve pulled together a variety of MK-677 before and after photos to see just what’s realistically possible. Ibutamoren is a very potent but slow-acting compound that takes a while to kick in but when it does, results are impressive.

Perhaps you’ve read that MK-677 is a SARM, or seen it referred to as Ibutamoren or Nutrobal and you’re probably wondering exactly what this wonder-compound is (and how it can help you with your strength and physique goals). The first thing you need to know is that Ibutamoren is not a SARM. Let’s find out more about this muscle-building, fat-stripping compound so you can make an informed decision about your cutting stack.

What Exactly Is Ibutamoren MK-677?

Ibutamoren is often marketed as a SARM (selective androgen receptor modulator) but it’s actually not a SARM at all. It’s a chemical compound which can boost your body’s natural hormone levels so you can speed up muscle growth for bigger, denser muscles, more mass, greater strength, and an easier time when you next try to lean down.

MK-677 is a growth hormone secretagogue; a substance that causes growth hormone and IGF-1 to be secreted in your body. It does this by imitating ghrelin, binding to ghrelin receptors in the brain, and encouraging your natural production of GH and IGF-1. Using Ibutamoren boosts your body’s own levels of these anabolic hormones without disturbing other hormones like testosterone or cortisol. This means it is safe for long-term use and doesn’t require any form of PCT.

Ibutamoren & Bodybuilding

As mentioned, Ibutamoren boosts your body’s levels of the anabolic hormones GH (growth hormone) and IGF-1. This means it has impressive anabolic properties but without the side effects associated with actual anabolic steroids.

Ibutamoren is taken orally and can help you increase muscle mass, boost muscle size and improve your strength in training too (which will obviously also lead to better gains). It can also help you lose more body fat during a cutting diet or a body recomposition phase.

This 1998 double-blind, randomised human study shows impressive results in a group of males given Ibutamoren MK-677 – they showed increased lean mass, GH secretion, and even energy expenditure in just two months. That same study showed that serum IGF-I increased by approximately 40% with Ibutamoren MK-677 treatment.

Our MK-677 before and after photos will follow soon, keep reading…

8 Benefits of MK-677

#1 Muscle retention

Ibutamoren has been shown to reverse protein loss and associated muscle wasting – good news for bodybuilders who want to diet to lose fat but hate the idea of sacrificing hard-earned muscle mass. Muscle gain made with HGH is longer-lasting, so any gains you make on Ibutamoren are likely to last longer, too.

#2 Muscle gain

Ibutamoren MK-677 doesn’t just help you hang on to muscle mass in the face of a possibly catabolic environment. It can also boost the growth of new muscle cells. It does this by stimulating secretion of GH and IGF-1 which increase protein synthesis. That means hefty gains if you’re already eating and training right.

#3 Bone density

All that extra growth hormone will mean better bone density in the short term and the long term, which is good news for your gains now, and for your health, once you get older. Look better and stay more active in later life? Yes, please.

#4 Sleep and recovery

Ibutamoren may improve the amount of REM sleep you get (and the quality of your sleep), which means better recovery between training and more time in that muscle-gaining anabolic state. Better sleep also means more energy for training the next day, plus less hunger and fewer cravings.

#5 Nootropics

Ibutamoren is also popular with the nootropic crowd because it is thought to have brain benefits. This means better wellbeing and mood, with more motivation and focus on training and cardio.

#6 Fat loss

Using Ibutamoren may encourage your body to use stored fat for energy, and remember that it protects muscle at the same time. This means true lean gains: fat loss with muscle gain for that full, pumped, shredded look. Our MK-677 before and after photos are specifically showing the fat-loss results that people have experienced.

#7 Anti-ageing and longevity

Ibutamoren may promote longevity by increasing growth hormone and IGF-1. IGF-1 is known to have beneficial effects on ageing and longevity, however, our natural production of growth hormone declines from mid-puberty throughout life. In a study with 65 healthy adults, daily administration of MK-677 increased GH and IGF-1 levels without negative side-effects. In another study with 24 obese males, MK-677 rejuvenated the growth hormone profile.

#8 Skin tightening

Ibutamoren is known for its positive effects on the quality of hair, skin and nails. Not only does it increase fat oxidation but you’ll also notice that it will also tighten the loose skin and improve the skin quality. This is also one of the reasons why it is often used for anti-ageing, as mentioned above. In fact, many women use MK-677 to combat wrinkles and cellulite!

MK-677 Before and After Photos

These MK-677 before and after photos show cycles of different lengths. It is worth noting that this compound shows greater results if used long-term and progress will also depend on different individual factors. Your diet, training, recovery and whether you decide to stack MK-677 will greatly affect your potential. Anecdotally, people are finding very noticeable and significant effects so it’s safe to say that MK-677 is worth its weight in gold.

mk 677 before and after 03
MK-677 Before and After – 12 Week Cycle
mk 677 before and after 01
MK-677 Before and After – 16 Week Cycle

If you looking for more than just MK-677 before and after photos, check out our SARMs Before and After Photos to see what else is available.

MK-677 Dosage & Stacking

Ibutamoren MK-677 can be taken by itself or as part of a stack with other compounds. It has a long half-life of 24 hours which means you can take your daily dose in one go – but it does spike growth hormone, so you might like to split your dose to avoid tiredness after the GH spike.

Most users will tend to use 20-25mg per day although MK-677 is still very effective at doses as low as 10mg, which can be useful for people who feel tired or hungry at higher doses. Start at 10mg for the first week to assess how you feel if it’s your first time using the compound.

The efficacy of MK-677 increases and improves with longer-term use, so the recommended cycle length is 3-6 months for optimum results. Some people like to stay on MK-677 year-round. Our MK-677 before and after photos show different cycle lengths but keep in mind that everyone is different and your training, diet, recovery and stacking will hugely affect results.

Recommended dosages:

  • Building muscle: 25mg per day
  • Fat loss: 20mg per day
  • Heal an injury: 10-20mg per day
  • Anti-ageing: 10-20mg per day

If you are new to Ibutamoren, start with 10mg for one week to assess your response before increasing dosages, if necessary.

Stacking MK-677 with SARMs

Ibutamoren has very minor side-effects, but it should still not be taken lightly. You still have to be careful when choosing your dose, especially if you plan on stacking it with other SARMs. And then you also have to figure out how to stack them.

But if you do choose the right dose and stack your SARMs properly, then you can expect amazing results in a short amount of time. Ibutamoren can actually enhance the effects of the SARMs that you’re currently taking.

MK-677 is often stacked with Cardarine, Ligandrol and Testolone but it is an exceptionally versatile compound and can be stacked with anything else. See our Stacks for recommendations based on your goals.

Our Best-Selling MK-677

You need to be sure the MK-677 you use is good quality, pure and well dosed. Be wary of any product which isn’t clearly labelled or can’t tell you how much of the active ingredient you are getting (we call this “micro-dosing” in the industry, and it’s bad news!).

Pumping Iron MK-677 (Ibutamoren) 10mg x 60 Tablets
Pumping Iron MK-677 (Ibutamoren)

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Cardarine GW-501516: A Complete Guide to GW501516
In Fat Loss, SARMs, Supplementsby

Cardarine GW-501516: A Helpful Guide 2019

In this article, we’ll cover everything you need to know about the PPAR-delta activator Cardarine (GW-501516), how long it takes to work, the ideal cycle length, safety and vital information you need before you consider adding it to your supplement regime.

A lot of the compounds we write about at PumpingIron.com are SARMs (selective androgen receptor modulators). This article is about something a little different, although often classed into the same category. GW501516 can help burn fat, boost metabolism, increase training endurance and protect muscle tissue but it isn’t actually a SARM. It’s a non-hormonal PPAR-delta activator which doesn’t work on the androgen capacitors at all.

If you’re curious about Cardarine, here’s everything you need to know and if we haven’t covered something, simply e-mail us and we’ll be happy to answer your questions!

Is Cardarine (GW-501516) a SARM?

As we said, Cardarine isn’t actually a SARM (anyone who tells you it is doesn’t know what they’re talking about). A SARM activates androgen receptors in muscles and other tissue. Cardarine is a PPAR-delta activator but it can produce results similar to those of SARMs.

Background Information

The best way to understand what to expect from a compound is to look at why it was developed (and what was discovered by researchers). GW501516 was originally developed by a drug company in the 1990s as a way to prevent tumours (especially on the colon and prostate). But there were some surprising discoveries.

During their studies into increased endurance and fat burning, the researchers began to understand more about the PPAR-delta pathway. They realised that activation of this pathway had an astounding impact on muscle growth, endurance and energy whilst decreasing blood lipids and subcutaneous fat. And – you guessed it – the compound GW-501516 can bind to this PPAR-delta pathway.

It turned out Cardarine could help reduce body fat, boost metabolic rate, improve the strength of blood vessels. This has a positive impact on cardiovascular health, increases muscle growth rate and even reduces recovery time. We’ll go into these factors in greater depth later in this article.

One thing we need to make clear: Cardarine is not currently sold for human consumption. It is classed as a ‘research compound’, sold for research purposes only.

How Long Does Cardarine Take to Work?

It’s important to understand how the Cardarine works in the body. Like we’ve already said, it binds to PPAR-delta in muscle cells and it stimulates certain genes which facilitate the body’s use of energy. Once you know that, you can see how it can boost your metabolic rate, improve physical performance and even help burn more fat (whilst increasing and protecting muscle mass).

You’ll notice the effects almost instantly; timing one of your dosages about thirty minutes before a high-intensity training session is an ideal protocol. The difference in energy, endurance and stamina will be noticeable almost immediately.

Burn Fat & Recover Faster with GW-501516

How exactly does Cardarine burn body fat? It’s not as simple as just torching fat right off your body. It starts with preventing the formation of fatty acids chains which, in turn, stops your body actually storing fat. This means your body needs to tap into your subcutaneous fat stores for energy – just like when you diet. But there’s one big difference to when you burn body fat by dieting. GW-501516 has those sought-after anti-catabolic properties, which means you get leaner without losing valuable muscle tissue.

What about boosting recovery between training sessions? It seems Cardarine can help your muscle fibres (specifically the slow-twitch fibres) use oxygen more efficiently, and this can help improve rates of recovery between training. It can also mean better endurance during training sessions. Good news if you train for hypertrophy, with a lower-load and higher-rep style of training.

Cardarine & Bodybuilding

You can already guess that this is an attractive compound for bodybuilders with its potential for muscle gain, training recovery and fat burning. (Side note: it’s also getting a lot of interest with the nootropics crowd.)

Cardarine could be used by itself or with other compounds as a cycle; you can stack it with prohormones, SARMs or other fat-burners. You can also use it to bridge between cycles or throughout a PCT (post cycle therapy) phase. Either way, it should be cycled for best results. Plan your cycle length for 8-12 weeks before having a 4-8 week break.

GW501516 has a half-life of 12-24 hours so you can decide whether to split your dose or to take it once per day. A dosage of 10mg-20mg per day is recommended.

Stacking Cardarine with Other Compounds

Cardarine can be used as a standalone supplement but is often stacked with other compounds. Most commonly, it has great synergistic effects with MK-677, RAD-140, Ostarine, LGD-3303 and Andarine.

It can also be used to combat negative side-effects of some anabolics (such as Trenbolone) and address potential lipid health issues. Cardarine is beneficial during PCT because it can lessen your chances of a fat-regain or rebound after running a steroid or prohormone cycle.

7 Things You Need To Know About Cardarine

#1 Fat Burner

It boosts your body’s fat-burning capacity by stimulating glucose and activating the ABCA1 and CPT1 fat-burning genes. Interestingly, there was a human study done on Cardarine’s potential for receding fatty acids, VLDL proteins and triglycerides (human studies on Cardarine are pretty rare, so it’s worth a look at this one).

#2 Training Endurance

It can stimulate the body’s glucose uptake, encouraging your body to use glucose as its primary fuel source. This means you get more energised for training and can train harder for longer. Since Cardarine can activate PPAR-delta pathways, it can also improve strength endurance. This 2015 study (on mice) suggests Cardarine can increase the specific muscle fibres associated with peak training performance.

#3 Lean Gains

It is a popular choice for stacking with SARMs and other compounds to protect lean muscle tissue whilst dieting to get shredded. As we’ve said, it can help burn body fat without the problem of losing muscle mass or looking over-dieted and scrawny.

#4 Brain Health

It can have a positive effect on blood vessels (see #5) and this means protection for your brain blood vessels (plus more blood to the brain). You might also like to know PPAR activators are thought to boost nerve cell development of nerve cells.

#5 Cardiovascular Health

It can prevent oxidative damage to blood vessels, helping reduce build-up in the arteries and (most exciting for bodybuilders) increasing your nitric oxide (NO) levels. This could mean Cardarine may reduce inflammation and associated tissue damage – a key factor in recovery and muscle growth during hypertrophy.

#6 Liver & Kidney Health

MCP-1 activity is a key factor in kidney disease and Cardarine can reduce this activity. Additionally, Cardarine acts directly on your liver (a powerhouse for storing fats for fuel in the body), using PPAR-delta activation to use fatty acids for energy. Cardarine could even reduce the body’s production of IL-6 and thereby prohibit insulin resistance.

#7 Muscle fibres

Activating PPAR-delta also means Cardarine can encourage better muscle fibre development. This means increased training endurance and the potential for greater muscle growth.

Choosing & Using Cardarine GW-501516

The bottom line is that Cardarine GW501516 is not currently legal for human consumption so it is sold for research purposes. Not for training, cutting, bulking, or bodybuilding.

You also need to bear in mind that Cardarine is banned for any tested bodybuilding competitions (yes, even trace amounts found accidentally in another product). At the moment, almost all the (limited) research on Cardarine GW501516 is on animals.

Don’t risk wasting your money on cheap, fake dupes!

One of the best selling products Mutagenic Labz Amalgamation combines a blend of GW-501516 and SR-9009, a very effective fat-loss combo. If you’re not keen on Cardarine just yet, Check out Mutagenic Labz Assimilation – our safe, legal and insanely effective GDA (Glucose Disposal Agent) to help you get leaner and build more muscle faster.

Disclaimer: By publishing this post we are not recommending using GW501516. It’s our duty to inform and educate you on all compounds. All of the information we have given here can be corroborated by published scientific reviews and literature. We recommend Mutagenic Labz Assimilation.

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