The Benefits of High Strength TUDCA (1000mg): A Comprehensive Guide

The Benefits of High Strength TUDCA (1000mg): A Comprehensive Guide

For users of SARMs and prohormones seeking potent liver protection and detoxification support, high strength TUDCA (1000mg) offers a valuable supplement option. Short for Tauroursodeoxycholic acid, TUDCA has garnered attention for its potential health benefits, particularly in supporting liver health and promoting overall well-being. Today, we delve into the advantages of high strength TUDCA, specifically the 1000mg dosage, and how it can make a difference in your health journey.

Understanding High Strength TUDCA (1000mg)

TUDCA is a bile acid produced naturally in the body and has gained popularity as a dietary supplement due to its potential therapeutic effects. When it comes to choosing a TUDCA supplement, the dosage plays a crucial role. High strength TUDCA, typically available in 1000mg capsules, offers a potent option for those seeking maximum benefits.

The Key Benefits of High Strength TUDCA:

1. Liver Health Support

  • TUDCA is renowned for its ability to support liver function and aid in liver detoxification processes. The high potency of 1000mg ensures a robust dose to help maintain optimal liver health.

2. Antioxidant Properties

  • As a powerful antioxidant, TUDCA helps combat oxidative stress in the body. This can contribute to overall well-being and support the body’s natural defenses against free radicals.

3. Gut Health Improvement

  • Research suggests that TUDCA may have a positive impact on gut health by promoting a healthy balance of gut bacteria. This can lead to improved digestion and absorption of nutrients.

4. Anti-Inflammatory Effects

  • High strength TUDCA has shown promise in reducing inflammation, making it beneficial for individuals dealing with inflammatory conditions.

Pumping Iron High Strength TUDCA

High Strength TUDCA for SARMs and Prohormones

For users of SARMs and Prohormones, incorporating high strength TUDC into their supplement regimen can offer essential cycle support, particularly for liver health and overall well-being.

Both SARMs and Prohormones can exert stress on the liver, as they undergo metabolic processes that may burden this vital organ. High strength TUDCA, with its potent liver-protective properties, becomes a valuable ally in this context. By promoting liver detoxification and aiding in the breakdown of toxins, TUDCA helps to alleviate the strain that SARMs and Prohormones can place on the liver during cycles.

Additionally, TUDCA’s anti-inflammatory effects and potential to lower cholesterol levels further contribute to overall cycle support, promoting a healthier internal environment during and after supplement usage. Including high strength TUDCA as part of cycle support not only enhances the effectiveness of SARMs and Prohormones but also prioritizes the user’s long-term health and well-being.

Benefits of TUDCA for Neurodegenerative Diseases

Tauroursodeoxycholic acid (TUDCA) has shown promising potential in the realm of neurodegenerative diseases, offering several benefits:

1. Neuroprotection:

  • TUDCA exhibits neuroprotective properties, shielding nerve cells from damage and promoting their survival. This can be particularly beneficial in conditions like Alzheimer’s and Parkinson’s disease, where neuronal damage contributes to symptom progression.

2. Anti-Inflammatory Effects:

  • Chronic inflammation is a common feature of many neurodegenerative diseases. TUDCA’s anti-inflammatory properties help reduce inflammation in the brain, potentially slowing down disease progression and alleviating symptoms.

3. Mitochondrial Support:

  • Mitochondrial dysfunction is implicated in various neurodegenerative disorders. TUDCA supports mitochondrial function, aiding in energy production and protecting neurons from mitochondrial-related damage.

4. Reduction of Endoplasmic Reticulum Stress:

  • Neurodegenerative diseases often involve endoplasmic reticulum (ER) stress, leading to cell dysfunction and death. TUDCA helps mitigate ER stress, promoting neuronal survival and function.

5. Improved Cognitive Function:

  • Studies suggest that TUDCA may enhance cognitive function and memory, offering potential benefits for individuals with neurodegenerative diseases affecting cognition.

6. Promotes Neuronal Growth and Repair:

  • TUDCA has been shown to stimulate the growth of new neurons (neurogenesis) and support the repair of damaged neuronal structures, which is crucial for recovery and slowing disease progression.

Pumping Iron TUDCA 1000mg (High Strength Liver Detox)


High strength TUDCA (1000mg) offers a potent supplement option for those looking to support liver health, combat oxidative stress, improve gut health, and reduce inflammation.

TUDCA’s multifaceted benefits for neurodegenerative diseases also make it a promising candidate for inclusion in treatment strategies aimed at preserving brain health, mitigating symptoms, and potentially slowing down the progression of these challenging conditions. Further research continues to uncover its full potential in improving the lives of those affected by neurodegenerative diseases.

With its myriad of potential benefits, high strength TUDCA could be a valuable addition to your wellness routine.

Buy the Pumping Iron High Strength TUDCA (1000mg) here!

Safest SARMs for Low Risk Gains

Safest SARMs for Proven Low Risk Gains (Ultimate Guide 2024)

Welcome to the comprehensive guide to the Safest SARMs for Low-Risk Gains. Within this extensive guide, we will delve into the realm of SARMs, offering valuable insights into the safest options for individuals seeking to enhance their physique, strength, and performance while minimizing potential risks.

Navigating the market saturated with various SARMs can pose a challenge in determining the compounds that strike the optimal balance between effectiveness and safety. Through extensive research, we have curated essential information to empower you to make informed decisions, enabling you to navigate the world of SARMs with confidence. Let’s embark on an exploration of low-risk SARMs, uncovering the leading contenders to help you achieve your fitness goals without compromising your health.

What are the safest SARMs for beginners?

Ostarine (MK-2866) stands out as one of the safest SARMs with the least reported side effects, widely acknowledged as the best SARM for beginners owing to its relatively mild nature and lower potency compared to other SARMs. With selective binding to androgen receptors in muscle and bone tissues, it promotes anabolic effects without significant androgenic side effects.

Initially developed to combat muscle-wasting diseases and osteoporosis, Ostarine has gained popularity among athletes and bodybuilders for its potential to foster muscle growth, enhance strength, and improve bone density. Its mild nature makes it an ideal choice of SARM for beginners or those seeking a less potent option with fewer side effects.

While ACP-105 and AC-262 show promise as safer alternatives to traditional anabolic steroids, they are relatively under-researched, and their safety profiles are not yet well-established.

However, it is crucial to emphasize that even the safest SARMs can pose risks if not used correctly. Safety considerations depend on factors such as dosage, cycle length, and individual response.

Overview of Selective Androgen Receptor Modulators (SARMs)

Let’s explore the scientific applications and provide a brief overview of the prominent Selective Androgen Receptor Modulators (SARMs), including the Safest SARMs (Ostarine, ACP-105, AC-262) alongside Andarine, Ligandrol, RAD-140, S-23, and YK-11. We’ll delve into their respective functionalities, potential benefits, and current research findings to offer a comprehensive understanding of each compound.

Ostarine (MK-2866)

Ostarine is considered one of the safest SARMs – initially developed to combat muscle-wasting diseases and osteoporosis. With its selective binding to androgen receptors in muscle and bone tissues, it stimulates anabolic effects without significant androgenic side effects. Due to its mild nature, Ostarine is often recommended for beginners or those seeking a relatively safe option. However, adherence to appropriate dosage guidelines and cycle duration remains essential.


ACP-105, a newer SARM, was developed as an alternative to traditional anabolic steroids for treating muscle-wasting diseases and osteoporosis. Demonstrating a robust anabolic effect with minimal androgenic side effects, ACP-105 has shown promising results in preclinical studies. Yet, its safety data from human trials is limited, necessitating further research to fully understand its safety profile.


AC-262 is another one of the safest SARMs exhibiting potential in preclinical studies. Developed to address conditions such as Alzheimer’s disease, prostate cancer, and muscle wasting diseases, it offers a moderate anabolic effect with minimal androgenic side effects. Similar to ACP-105, human trial safety data is limited, warranting additional research to establish its safety profile.

Andarine (S4)

Initially developed to treat osteoporosis and muscle-wasting diseases, Andarine boasts a higher affinity for androgen receptors than Ostarine but can cause more side effects, including temporary visual disturbances. These side effects typically resolve upon discontinuation of the compound. If it wasn’t for these side effects, S-4 would be amongst the safest SARMs (often recommended for female athletes).

Cardarine and SR-9009

Often grouped into the same category as the safest SARMs, SR-9009 (Stenabolic) and Cardarine (GW-501516) differ in their mechanisms of action. Acting through different pathways, they impact endurance, fat loss, and metabolic function. Due to their non-androgenic nature, these compounds are generally considered to have fewer side effects related to hormonal disruption, such as testosterone suppression, commonly associated with SARMs.

Ligandrol (LGD-4033)

Designed to address muscle wasting conditions and age-related muscle loss, Ligandrol is more potent than Ostarine. However, this potency increases the potential for side effects, such as heightened suppression of natural testosterone production. Proper Post Cycle Therapy (PCT) is often recommended after a Ligandrol cycle to restore hormonal balance.

RAD-140 (Testolone)

RAD-140 stands out as one of the most potent SARMs, developed to treat muscle-wasting diseases and breast cancer. Its potency carries a higher risk of side effects, including testosterone suppression and liver strain. Recommended for experienced users, it should be used with caution, following appropriate dosage and cycle lengths.


As a newer and more potent SARM, S-23 is primarily researched for potential use in male hormonal contraception. Noted for its high anabolic activity, it carries a higher risk of side effects, including significant testosterone suppression. Proper PCT is crucial after a cycle of S-23.


YK-11 is a unique compound, acting as both a SARM and a myostatin inhibitor. It promotes muscle growth by inhibiting myostatin, a protein that limits muscle growth. However, YK-11 is relatively under-researched compared to other SARMs, and its safety profile is not well-established. The potential side effects and long-term implications of YK-11 use are not fully understood.

What are the dangers of SARMs?

Do SARMs cause erectile dysfunction?

SARMs can potentially suppress the body’s natural testosterone production, leading to hormonal imbalances that may result in symptoms such as decreased libido and erectile dysfunction. The severity of testosterone suppression depends on factors like SARM potency, dosage, and cycle length. While milder options like Ostarine (MK-2866) are less likely to cause significant testosterone suppression, more potent SARMs like S-23 can lead to more severe hormonal imbalances.

To minimize the risk of erectile dysfunction and other SARM-related side effects, adhering to appropriate dosage guidelines and cycle durations is crucial. Some users may require Post Cycle Therapy (PCT) after a cycle to help restore hormonal balance and alleviate symptoms associated with low testosterone levels, including erectile dysfunction.

Do SARMs cause liver damage?

As SARMs are typically taken orally, passing through the liver, precautions should be taken to minimize potential stress or damage. Notably, SARMs like RAD-140 (Testolone) or LGD-4033 (Ligandrol) may carry a higher risk of liver toxicity. It is crucial to follow appropriate dosage guidelines and cycle durations, avoid simultaneous use of multiple SARMs, and monitor liver function through blood tests during and after the cycle.

Maintaining a healthy lifestyle, including a balanced diet, regular exercise, and adequate hydration, is also essential to support liver health during a SARM cycle. Excessive alcohol consumption and the use of substances that may cause liver damage should be avoided.

Do SARMs affect sperm count?

The impact on sperm count varies based on factors such as the specific SARM used, dosage, cycle duration, and individual response. The safest SARMs like Ostarine (MK-2866) and AC-262 are less likely to cause significant testosterone suppression, while more potent ones like S-23 can lead to pronounced hormonal imbalances.

It is important to note that the reduction in sperm count caused by SARMs is typically temporary. Upon completing the SARM cycle and the resumption of natural testosterone production, sperm count generally returns to normal levels. In some cases, Post Cycle Therapy (PCT) may be necessary to expedite hormonal balance restoration and the recovery of sperm count.

Do SARMs cause hair loss?

SARMs pose a lower risk of inducing hair loss compared to traditional anabolic steroids, although the potential for such an effect still exists. The likelihood of experiencing hair loss from SARMs depends on factors such as the specific SARM used, dosage, cycle duration, and an individual’s predisposition to hair loss or androgenic alopecia.

Designed to selectively target androgen receptors in muscle and bone tissues, SARMs promote anabolic effects without many of the androgenic side effects associated with steroids. Nevertheless, some SARMs may exhibit a degree of androgenic activity, contributing to hair loss in genetically susceptible individuals.

The risk of hair loss varies among different SARMs. The safest SARMs such as Ostarine (MK-2866) are not likely to cause this side effect, while more potent SARMs, such as RAD-140 (Testolone), might carry a higher risk.

It is crucial to note that not everyone using SARMs will experience hair loss. Genetic factors play a significant role, and individuals with a family history of androgenic alopecia may be more susceptible to hair loss when using SARMs or other androgenic compounds.

Are SARMs bad for your heart?

SARMs can have both potential benefits and drawbacks concerning heart health, influenced by factors like the specific SARM used, dosage, cycle duration, and individual response.

Some studies suggest potential indirect benefits on cardiovascular health due to their impact on muscle growth and body composition. Enhanced muscle mass and reduced body fat can contribute to improved cardiovascular fitness, reduced inflammation, and enhanced insulin sensitivity.

However, it’s crucial to acknowledge that research on the cardiovascular benefits of SARMs is still limited, requiring further studies to fully comprehend their potential effects on heart health.

Potential beneficial effects on heart health:

  1. Ostarine (MK-2866): Ostarine, extensively researched and initially developed for treating muscle-wasting diseases and osteoporosis, has demonstrated the ability to promote muscle growth and improve body composition. These effects could potentially have indirect positive implications for heart health. It is considered one of (if not the) safest SARMs on the market.
  2. Cardarine (GW-501516): Although not technically a SARM, Cardarine is often associated with SARMs due to its similar effects on muscle growth and fat loss. As a PPARδ agonist, it has shown potential benefits such as increased endurance, improved lipid profiles, and reduced inflammation in some studies. These effects could positively impact cardiovascular health, though concerns about potential long-term effects, including an increased risk of cancer, exist.

Potential detrimental effects on heart health:

SARMs can have several negative effects on heart health. Even if you are using the safest SARMs, you must always be aware of potential risks including:

  1. Lipid profile changes: Some SARMs can negatively impact cholesterol levels, increasing LDL (bad) cholesterol and decreasing HDL (good) cholesterol. These changes may potentially elevate the risk of atherosclerosis and cardiovascular disease.
  2. Blood pressure: SARMs may cause an increase in blood pressure, particularly in individuals using high doses or for extended periods. Elevated blood pressure is a known risk factor for cardiovascular disease.

To minimize potential negative effects on heart health, adherence to appropriate dosage guidelines and cycle durations is crucial. Regular cardiovascular health monitoring during a SARM cycle and maintaining a healthy lifestyle, including regular exercise and a balanced diet, are essential.

Unknown Long-term Effects

Numerous SARMs are still relatively new and under-researched, which means their long-term effects on health are not yet fully understood. While short-term use may appear to be relatively safe, the potential risks associated with long-term use are not well-established, even if they are considered one the safest SARMs.

Contaminated or Counterfeit Products

The SARMs market is largely unregulated, which increases the risk of purchasing contaminated or counterfeit products. Some products may contain harmful substances, incorrect dosages, or other active ingredients not listed on the label. To minimize this risk, it is crucial to purchase SARMs from reputable sources.

Potential Interactions with Medications

SARMs may interact with other medications, causing unwanted side effects or reducing the effectiveness of the medication. It is essential to consult a healthcare professional before starting a SARM cycle (even if it’s one of the safest SARMs), especially if you are taking any medications.

What Happens If You Take SARMs for Too Long?

Taking SARMs for extended periods or beyond the recommended cycle duration (even if it’s one of the safest SARMs) can increase the risk of experiencing negative side effects and potentially cause long-term health issues. Some potential consequences of taking SARMs for too long include:

  • Hormonal Imbalances
  • Liver Stress or Damage
  • Negative Effects on Lipid Profile
  • Dependency
  • Unknown Long-term Effects

How Long Can You Stay on SARMs?

The recommended cycle length for SARMs can vary depending on the specific compound, individual goals, and personal tolerance. However, some general guidelines can be followed:

Mild SARMs – considered the safest SARMs (Ostarine/MK-2866, Andarine/S4, ACP-105, AC-262): Typically used in cycles of 8-12 weeks, followed by an equal or longer off-cycle period to allow the body to recover.

Potent SARMs (RAD-140/Testolone, LGD-4033, YK-11, or S-23): These may require shorter cycles of 6-8 weeks due to their potency and potential for increased side effects. An off-cycle period equal to or longer than the on-cycle duration is recommended.

Keep in mind that these guidelines may not apply to everyone, and individual factors, such as age, health status, and previous experience with SARMs, can influence the optimal cycle length.

What’s Safer: SARMs or Steroids?

SARMs (Selective Androgen Receptor Modulators) are generally considered to be safer than traditional anabolic steroids due to their selective mechanism of action. They were developed to provide the anabolic effects of steroids with fewer side effects.

Some reasons why SARMs are considered to be safer than steroids include:

Selectivity: SARMs target specific androgen receptors in muscle and bone tissue, which reduces the risk of side effects commonly associated with steroids, such as acne, hair loss, and prostate enlargement.

Lesser Hormonal Disruption: SARMs typically cause less suppression of natural testosterone production than anabolic steroids, reducing the risk of long-term hormonal imbalances.

No Conversion to Estrogen or DHT: Unlike some anabolic steroids, SARMs do not convert to estrogen or dihydrotestosterone (DHT), which can cause side effects such as gynecomastia, water retention, and prostate issues.

Oral Administration: Most SARMs are taken orally, which eliminates the need for injections and the associated risks of infection and scarring.

Is There a Superior Alternative to the Safest SARMs?

The existence of a superior alternative to SARMs hinges on your individual goals, health status, and personal preferences. Several alternatives to SARMs are worth considering:

Natural Training and Nutrition: A well-structured training program coupled with a balanced, nutrient-rich diet forms the cornerstone for achieving fitness objectives without resorting to performance-enhancing compounds. This approach is the safest and most sustainable means of building muscle, strength, and overall fitness.

Supplements: Legal and widely available supplements can bolster muscle growth, recovery, and performance. Examples include protein powders, creatine, branched-chain amino acids (BCAAs), and beta-alanine. When used alongside an appropriate training and nutrition regimen, these supplements can be beneficial.

Peptides: Peptides, such as growth hormone-releasing peptides (GHRPs) and growth hormone secretagogues, can offer anabolic effects, support recovery, and facilitate fat loss. However, their use may entail potential side effects and legal considerations depending on the jurisdiction.

Ultimately, the most suitable option for you will be contingent on your goals, risk tolerance, and commitment to a healthy lifestyle.

Glucose Disposal Agent: Ultimate Guide to Shredded Gains (2023)

Glucose Disposal Agent: Ultimate Guide to Shredded Gains (2024)

A high quality Glucose Disposal Agent (GDA) supplement can be the game-changer in your quest for shredded gains. A GDA can improve insulin sensitivity, enhance glucose uptake into muscle cells, and promote glycogen synthesis. By improving nutrient partitioning and reducing fat storage, GDAs have garnered heavy interest among bodybuilders and athletes, and for very good reason. Here’s the ultimate guide to help you utilise this amazing supplement to take your progress to the next level.

What is a Glucose Disposal Agent?

A Glucose Disposal Agent supplement is designed to improve the way the body manages glucose (blood sugar) levels. The primary goal of a GDA is to enhance insulin sensitivity and facilitate the transportation of glucose into muscle cells, rather than storing it as fat. GDAs have gained popularity in the fitness and bodybuilding communities due to their potential benefits in improving nutrient partitioning, enhancing muscle gains, and promoting fat loss.

How does a Glucose Disposal Agent work?

1. Insulin and Glucose Metabolism: Before delving into glucose disposal agents, it’s essential to understand insulin’s role in glucose metabolism. Insulin is a hormone secreted by the pancreas in response to elevated blood glucose levels, such as after eating a meal containing carbohydrates. Insulin acts as a “key” that allows glucose to enter cells, where it can be used for energy or stored for future use.

Insulin resistance is a condition where cells become less responsive to insulin, leading to higher blood glucose levels. When insulin resistance occurs, the body compensates by producing more insulin, potentially leading to chronically elevated insulin levels. High insulin levels can contribute to fat storage and other metabolic issues.

2. Mechanism of Glucose Disposal Agents: GDAs work to improve insulin sensitivity, which means they help cells respond more effectively to insulin’s signaling. They may do this through various mechanisms, including:

a. GLUT4 Translocation: One of the primary mechanisms involves promoting the translocation of glucose transporter type 4 (GLUT4) to the cell surface. GLUT4 is responsible for facilitating glucose entry into muscle and fat cells. GDAs may enhance this process, allowing more glucose to be transported into muscle cells for energy use and glycogen storage, rather than being converted to fat.

b. Increased Glycogen Synthesis: GDAs can stimulate the synthesis of glycogen, the stored form of glucose in muscles and the liver. Increased glycogen storage can enhance endurance, strength, and recovery during workouts.

c. Inhibition of Glucose Production: Some GDAs may also reduce the liver’s production of glucose, further aiding in maintaining balanced blood sugar levels.

d. Enhanced Fat Oxidation: Some GDAs have been proposed to promote fat oxidation (fat burning) and reduce fat storage by improving insulin sensitivity.

What are the best Glucose Disposal Agents on the market?

Several ingredients have been researched and shown promising results as Glucose Disposal Agents in terms of improving insulin sensitivity and glucose uptake into cells. Here are some of the best GDA ingredients known at that time:

  1. Alpha-Lipoic Acid (ALA): ALA is a potent antioxidant that has been extensively studied for its potential benefits in improving insulin sensitivity. It may enhance glucose uptake into cells and reduce oxidative stress, making it one of the popular GDA ingredients.
  2. Berberine: Berberine is a bioactive compound found in several plants. It has been used in traditional medicine for various purposes, including improving glucose metabolism and insulin sensitivity. Studies suggest that berberine activates AMP-activated protein kinase (AMPK), which plays a role in glucose uptake and energy regulation.
  3. Cinnamon Extract: Cinnamon is a popular spice known for its potential to improve insulin sensitivity. Cinnamon extracts, particularly those high in bioactive compounds like cinnamaldehyde, have been studied for their glucose-lowering effects.
  4. Fenugreek: Fenugreek is an herb that has been researched for its potential to lower blood sugar levels and improve insulin sensitivity. It contains soluble fiber and compounds like trigonelline that may contribute to its GDA properties.
  5. Chromium: Chromium is an essential mineral that plays a role in carbohydrate and lipid metabolism. Some studies suggest that chromium supplementation may improve insulin sensitivity and glucose disposal.
  6. Bitter Melon (Momordica charantia): Bitter melon is a tropical fruit that has been traditionally used in various cultures to manage blood sugar levels. It contains compounds with potential GDA properties, such as charantin and polypeptide-p.
  7. Gymnema Sylvestre: Gymnema sylvestre is an herb known as the “sugar destroyer.” It has been used in traditional medicine for its potential to reduce sugar absorption in the intestine and enhance insulin function.
  8. R-Alpha-Lipoic Acid (R-ALA): R-ALA is the biologically active form of alpha-lipoic acid. Some studies suggest that R-ALA may be more effective than the regular form in improving insulin sensitivity and glucose uptake.
  9. Vanadium: Vanadium is a trace mineral that has been studied for its potential insulin-like effects, which may help improve glucose metabolism.
  10. Chitosan: Chitosan is a fiber derived from the shells of crustaceans. Some research suggests that it may improve insulin sensitivity and reduce blood sugar levels.

Does a Glucose Disposal Agent help with muscle growth?

A high quality Glucose Disposal Agent can contribute to muscle growth by improving nutrient partitioning and enhancing insulin sensitivity. While GDAs themselves do not directly promote muscle growth like traditional muscle-building supplements (e.g., protein powders, creatine), they can play a supportive role in the process. Here’s how a glucose disposal agent may help with muscle growth:

1. Improved Nutrient Partitioning: Nutrient partitioning refers to how the body allocates and utilizes nutrients, such as carbohydrates and amino acids. GDAs may help direct a larger portion of the nutrients, particularly glucose and amino acids, toward muscle cells for growth and repair instead of storing them as fat. This can create a more favorable environment for muscle development.

2. Increased Glycogen Storage: GDAs can enhance glycogen synthesis, the storage form of glucose in muscles and the liver. Having ample glycogen reserves is essential for providing energy during workouts and promoting muscle recovery and growth post-exercise.

3. Enhanced Insulin Sensitivity: GDAs work to improve insulin sensitivity, which means the body becomes more responsive to insulin’s signaling. Higher insulin sensitivity allows for more efficient nutrient uptake into muscle cells, especially after a meal, when nutrient absorption is essential for muscle recovery and growth.

4. Better Post-Workout Recovery: By promoting better nutrient uptake and glycogen storage, GDAs can aid in post-workout recovery. Enhanced recovery supports muscle repair and growth, as muscles often grow stronger during the recovery phase.

5. Potential Reduction in Fat Gain: Some GDAs have been associated with reduced fat storage and improved fat oxidation. By minimizing fat gain and promoting a leaner body composition, GDAs may indirectly enhance the appearance of muscle definition.

Can GDAs improve insulin sensitivity?

Yes, Glucose Disposal Agents can improve insulin sensitivity. In fact, improving insulin sensitivity is one of the main mechanisms through which GDAs are believed to exert their effects.

Insulin sensitivity refers to how responsive the cells in your body are to insulin’s signaling. When you have good insulin sensitivity, your cells effectively take up glucose from the bloodstream in response to insulin, helping to regulate blood sugar levels. On the other hand, insulin resistance occurs when cells become less responsive to insulin, leading to higher blood sugar levels and potentially contributing to various metabolic issues, including type 2 diabetes and weight gain.

GDAs work to enhance insulin sensitivity through various mechanisms, including:

1. GLUT4 Translocation: One of the primary mechanisms involves promoting the translocation of glucose transporter type 4 (GLUT4) to the cell surface. GLUT4 is responsible for transporting glucose into cells, particularly muscle and fat cells. GDAs may enhance this process, making cells more responsive to insulin and improving glucose uptake.

2. Activation of AMPK: Some GDAs, such as berberine, have been shown to activate AMP-activated protein kinase (AMPK). AMPK is an enzyme that plays a crucial role in energy regulation and metabolism. Activating AMPK can enhance insulin sensitivity and glucose uptake into cells.

3. Reduced Gluconeogenesis: GDAs may help reduce the liver’s production of glucose, a process known as gluconeogenesis. By limiting excess glucose production, blood sugar levels can be better controlled, reducing the demand for insulin.

4. Improved Fat Oxidation: Some GDAs have been associated with increased fat oxidation (fat burning), which can help reduce intracellular lipid accumulation and improve insulin sensitivity.

By improving insulin sensitivity, GDAs help the body more efficiently manage glucose, which can have several benefits, including:

  • Lowering blood sugar levels and reducing the risk of type 2 diabetes.
  • Promoting better nutrient partitioning, directing nutrients like glucose and amino acids toward muscle cells for growth and recovery.
  • Enhancing glycogen storage in muscles, improving exercise performance and recovery.
  • Supporting weight management and reducing the likelihood of excess fat storage.

Are there any side effects from Glucose Disposal Agents?

Glucose Disposal Agents are generally considered safe for most healthy individuals when used as directed. However, like any supplement, GDAs may have potential side effects, especially when taken in excessive amounts or by individuals with certain medical conditions. It’s essential to be aware of possible side effects and consult with a healthcare professional before using GDAs, particularly if you have any underlying health issues or are taking medications. Some potential side effects include:

  1. Hypoglycemia, more likely to occur if GDAs are taken alongside medications or other supplements that lower blood sugar levels
  2. Digestive Issues such as bloating and gastrointestinal discomfort
  3. Allergic Reactions in some people
  4. Liver and Kidney Function at high doses and extended periods of time

When is the best time to take a Glucose Disposal Agent?

The best time to take a Glucose Disposal Agent can vary depending on your specific goals and individual needs. It is essential to follow the manufacturer’s instructions and, if available, consult with a healthcare professional or a certified nutritionist for personalized guidance. Here are some general guidelines for when to take a GDA:

1. With Carbohydrate-Containing Meals: GDAs are commonly taken with meals that contain carbohydrates. This is because GDAs are designed to help improve insulin sensitivity and enhance glucose uptake into cells, particularly muscle cells. Taking GDAs with carbohydrate-rich meals can optimize their effects on nutrient partitioning, directing glucose and nutrients toward muscle cells for potential muscle growth and recovery.

2. Pre-Workout: Some individuals prefer taking GDAs before their workout, especially if they are consuming a pre-workout meal that includes carbohydrates. The idea behind this approach is to enhance nutrient delivery and glycogen storage in muscles, providing extra energy for the upcoming workout.

3. Post-Workout: Others choose to take GDAs post-workout, along with a post-workout meal or shake containing carbohydrates and protein. This can aid in replenishing glycogen stores in muscles and facilitating recovery and muscle repair.

4. During High-Carb Days: For individuals following a cyclical or targeted ketogenic diet, where they have designated days of higher carbohydrate intake, taking a GDA on those high-carb days may help manage blood sugar levels and promote nutrient uptake.

5. On Refeed Days: Similarly, individuals who follow intermittent fasting or calorie-restricted diets might incorporate “refeed” days or meals where they consume higher amounts of carbohydrates. Taking GDAs on these refeed occasions can support the body’s response to the sudden increase in glucose intake.

6. Before Cheat Meals: Some individuals use GDAs before cheat meals or larger indulgent meals to help manage blood sugar levels and potentially minimize the impact of excess carbohydrates.

To maximize the benefits, it’s crucial to maintain a balanced diet, engage in regular exercise, and consider other lifestyle factors that can influence insulin sensitivity and glucose metabolism.

Enhanced Labs SLIN (120 Capsules)
Enhanced Labs SLIN (120 Capsules)

Can a glucose disposal agent help with fat loss?

While GDAs themselves do not directly promote fat loss like traditional fat burners or thermogenic supplements, their effects on insulin sensitivity and glucose metabolism may offer some benefits for individuals aiming to lose body fat. Here’s how GDAs may be related to fat loss:

1. Improved Nutrient Partitioning: By enhancing nutrient partitioning, GDAs may help reduce the amount of glucose and nutrients being stored as fat and instead direct them toward muscle cells. This can create a more favorable environment for maintaining or increasing lean muscle mass while reducing fat storage.

2. Reduced Fat Gain: GDAs may potentially minimize the impact of high-carbohydrate meals on fat storage. By improving insulin sensitivity, GDAs can help prevent excessive spikes in blood sugar levels and the subsequent release of insulin, which is associated with fat storage.

3. Increased Muscle Mass: As GDAs support muscle growth and recovery by promoting glucose uptake into muscle cells, having more lean muscle mass can contribute to a higher resting metabolic rate, potentially aiding in fat loss efforts.

4. Energy Utilization: GDAs may help improve the body’s ability to utilize glucose for energy during exercise. This can enhance workout performance and calorie expenditure during physical activity, which may contribute to fat loss.

Are GDAs suitable for individuals with diabetes?

The use of Glucose Disposal Agents in individuals with diabetes should be approached with caution, and it’s essential to consult with a healthcare professional before considering their use. GDAs can have effects on glucose metabolism, insulin sensitivity, and blood sugar levels, which may interact with medications and the individual’s existing diabetes management plan.

Are GDAs effective for post-workout recovery?

A Glucose Disposal Agent can play a supportive role in post-workout recovery, but their effectiveness may depend on various factors and individual responses. GDAs primarily work by improving insulin sensitivity and promoting the uptake of glucose into cells, particularly muscle cells. This can have several potential benefits for post-workout recovery:

1. Glycogen Replenishment: After a workout, muscles may have depleted their glycogen stores, which are the stored form of glucose used for energy during exercise. GDAs may enhance glycogen synthesis, facilitating the replenishment of glycogen in muscle cells, leading to faster recovery and improved performance for subsequent workouts.

2. Nutrient Uptake: GDAs can improve nutrient partitioning, directing glucose and nutrients toward muscle cells rather than fat cells. This can facilitate the uptake of essential nutrients, such as amino acids from protein, into muscle tissue for repair and recovery.

3. Insulin Response: GDAs may support a more controlled and efficient insulin response after a workout. Proper insulin sensitivity can help manage blood sugar levels and optimize nutrient delivery to muscles, aiding in recovery and reducing the risk of excessive fat storage.

4. Reduced Muscle Soreness: Enhanced post-workout nutrient uptake and glycogen replenishment can contribute to reduced muscle soreness and faster recovery between workouts.

However, it’s important to note that GDAs are not a substitute for a well-rounded post-workout recovery plan. The most critical factors for effective post-workout recovery include:

1. Nutrition: Consuming a balanced meal or post-workout shake that includes protein, carbohydrates, and some healthy fats can support muscle recovery and glycogen replenishment.

2. Hydration: Proper hydration is crucial for overall recovery and performance. Drink enough water throughout the day and after workouts.

3. Rest and Sleep: Allow sufficient time for rest and recovery between intense workouts. Sleep is a critical component of the recovery process.

4. Active Recovery: Engage in light activities like walking or gentle stretching to promote blood flow to muscles and reduce stiffness.

5. Protein Intake: Ensure you consume an adequate amount of protein to support muscle repair and growth.

GDAs can be used as part of a post-workout recovery strategy to optimize nutrient uptake and glycogen replenishment. However, individual responses may vary, and their effects should be considered alongside other essential recovery practices.

How long does a Glucose Disposal Agent take to show results?

The time it takes to see results from using Glucose Disposal Agent can vary depending on several factors, including individual physiology, diet, exercise regimen, and the specific GDA being used. As with most supplements, results are not typically instantaneous, and patience and consistency are essential.

9 Important Vitamins and Minerals Essential for Bodybuilding and Strength

9 Important Vitamins and Minerals Essential for Bodybuilding and Strength

9 important vitamins and minerals can make or break your bodybuilding and strength endeavours.

Micronutrients are essential for optimal health and performance. These nutrients, including vitamins and minerals, play crucial roles in various bodily functions such as energy metabolism, immune system function, and tissue repair. Here, we will discuss 9 important vitamins and minerals that are essential for optimal performance. We also list which foods will provide you with the highest daily intake.

9 important vitamins and minerals

Maintaining optimal health and performance requires a nutrient-rich diet containing essential vitamins and minerals. By incorporating diverse food sources into your regimen, you can be sure to get the needed amounts of these key elements for wellbeing. Here is our list of 9 important vitamins and minerals:


Iron is an essential nutrient for athletes, providing oxygen and energy to active muscles. To ensure maximum absorption, pair your meals like legumes or grains that contain Iron with vitamin C rich fruits and veggies – this can help increase uptake up 4-6 times more than usual! Avoid caffeine beverages alongside; even something seemingly harmless such as coffee could impede iron absorption if consumed together .

Vegans may struggle with their iron levels as non-heme plants sources are not as easily absorbed by the body compared to heme from meat products.

How much do you need? men: 8 mg/day, women: 18 mg/day

Get it from:

  • 1 serving 50% fortified breakfast cereals – 9 mg or 50% of your daily value
  • 3 oz oysters – 8 mg or 44% of your daily value
  • 3 oz dark chocolate – 7 mg or 39% of your daily value
  • ½ cup lentils – 3 mg or 17% of your daily value
  • ½ cup tofu – 3 mg or 17% of your daily value
  • 1/2 cup kidney beans – 2 mg or 11% of your daily value

Vitamin B12

Vitamin B12 helps fuel your body for optimal performance! It’s essential for the production of red blood cells that carry oxygen to muscles, as well protein synthesis – key processes in building and maintaining muscle. Not meeting adequate intake can mean anemia and seriously decreased energy levels, especially among vegan athletes or those who limit their caloric intake. Ensure you stay on top of Vitamin B12 needs to be at peak athletic conditioning!

How much do you need? 2.4 mcg/day

Get it from:

  • 3 oz salmon – 4.8 mcg or 200% of your daily value
  • 3 oz tuna – 2.5 mcg or 104% of your daily value
  • 3 oz beef – 1.4 mcg or 58% of your daily value
  • 1 cup milk- 1.2 mcg or 50% of your daily value
  • 1 large egg – 0.6 mcg or 25% of your daily value

Vitamin D

Vitamin D is essential for athletes to maintain healthy muscle function, strength and performance. Even though it can be stored in the body after absorbing sunlight, foods such as eggs or seafood are great sources of natural vitamin D. At the same time, vegans may also want to consider fortified plant milks and cereals along with direct exposure to sun rays as a way of obtaining their recommended daily intake of this nutrient.

How much do you need? 600 IUs/day

Get it from:

  • 3 oz. salmon – 715 IUs or 119% of your daily value
  • 1 cup fortified orange juice – 137 IUs or 23% of your daily value
  • 1 cup fortified milk – 115 IUs or 19% of your daily value
  • 1 large egg – 41 IUs or 7% of your daily value


Staying physically active is a sure-fire way to maintain your health, but there’s one mineral that can help keep you strong and energised: calcium. For regular gymrats, this crucial nutrient gives your muscles the power they need for each contraction while also helping promote healthy bones in the long term. Additionally, studies have indicated dairy products high in calcium may be able to aid with weight loss by increasing fat burning – something we could all use more of!

How much do you need? 1,000 mg/day

Get it from:

  • 1 cup plain yogurt – 415 mg or 42% of your daily value
  • 1.5 ounces mozzarella cheese – 333 mg or 33% of your daily value
  • 3 oz canned sardines – 325 mg or 33% of your daily value
  • 1 cup fortified orange juice – 345 mg or 35% of your daily value
  • 1 cup fortified soy milk – 299 mg or 30% of your daily value
  • 1 cup milk – 275 mg or 28% of your daily value
  • ½ cup tofu – 138 mg or 14% of your daily value
  • ½ cup turnip greens – 99 mg or 10% of your daily value


Magnesium plays a vital role in our bodies, helping to promote optimal muscle function and bone formation while aiding energy metabolism. Athletes need even more magnesium due to the amount lost through sweat. Unlike some other nutrients whose daily needs can be satisfied from 2 to 3 servings of rich sources, most foods containing magnesium only provide 10-20% of your daily value, so including a variety of sources in your diet is key.

How much do you need? men: 420 mg/day, women: 320 mg/day

Get it from:

  • 3 oz almonds – 80 mg or 20% of your daily value
  • ½ cup cooked spinach – 78 mg or 20% of your daily value
  • 3 oz cashews – 74 mg or 19% of your daily value
  • ½ cup black beans – 60 mg or 15% of your daily value
  • 2 tbsp peanut butter – 49 mg or 12% of your daily value
  • ½ cup brown rice – 42 mg or 11% of your daily value


With zinc being an essential mineral for numerous bodily processes, it’s important to ensure you’re getting enough in your diet. Athletes may be particularly at risk of deficiency due its role in muscle recovery – fatigue and a decrease in performance can indicate that more zinc is needed! Fortunately, there are plenty of ways to get the necessary daily intake; shellfish and meat provide some great sources while plant-based eaters should look towards fortified foods or nuts/beans as alternatives.

How much do you need? men: 11 mg/day, women: 8 mg/day

Get it from:

  • 3 oz oysters – 74 mg or 493% of your daily value
  • 3 oz king crab – 6.5 mg or 43% of your daily value
  • 3 oz beef patty – 5.3 mg or 35% of your daily value
  • 1 serving 25% fortified breakfast cereals – 3.8 mg or 25% of your daily value
  • 3 oz dark meat chicken – 2.4 mg or 16% of your daily value
  • ½ cup baked beans – 2.9 mg or 19% of your daily value
  • 1 ounce cashews – 1.6 mg or 11% of your daily value


Iodine is necessary for the production of thyroid hormones, which play a role in metabolism. A deficiency can lead to decreased metabolism and fatigue. Good food sources include seafood and fortified foods.

How much do you need? men and women: 150mcg/day, pregnant women: 220mcg/day, and lactating women 290mcg/day

Get it from: 

    • 3 oz (85 grams) cod – 63–99 mcg, or 42–66% of your daily value
    • 1 cup (8 ounces) milk – 88-168 mcg, or 59–112% of your daily value
    • 1 cup cottage cheese – 65 mcg, or 43% of your daily value
    • 3 oz shrimp – 35 mcg, or 23% of your daily value
    • 1 large egg – 24 mcg, or 16% of your daily value
    • 3 oz tuna  – 17 mcg, or about 11% of your daily value


Keeping your body in balance is important for overall health, and potassium plays an essential role. An electrolyte powerhouse, this mineral aids with hydration, recovery and even helps to stave off muscle cramps – especially when you perspire more than usual. Fortunately it’s not hard to get enough of the nutrient; many plant-based foods provide a great source of potassium beyond bananas!

How much do you need? 4,700 mg/day

Get it from:

  • ½ cup dried apricots – 1,101 mg or 31% of your daily value
  • 1 cup lentils – 731 mg or 21% of your daily value
  • ½ cup raisins – 618 mg or 18% of your daily value
  • 1 medium baked potato – 610 mg or 17% of your daily value
  • 1 cup kidney beans – 607 mg or 17% of your daily value
  • 1 cup orange juice – 496 mg or 14% of your daily value
  • 1 medium banana – 422 mg or 12% of your daily value

Vitamin E

Athletes who often participate in endurance and high intensity training may be at an increased risk of developing upper respiratory infections due to the “open window” theory. This suggests that their immune system could become suppressed for multiple hours after exercising, leaving them more vulnerable to infection.

Eating a nutritious diet full of vitamins C & E may help prevent this from occurring; vitamin E acts as a powerful antioxidant helping lessen physical strain while also improving aerobic fitness levels.

How much do you need? 15 mg/day

Get it from:

  • 1 Tbsp wheat germ oil – 20 mg or 133% of your daily value
  • 1 oz sunflower seeds – 7.4 mg or 50% of your daily value
  • 1 oz almonds – 7 mg or 47% of your daily value
  • 2 tbsp peanut butter – 3 mg or 20% of your daily value
  • ½ cup cooked spinach – 2 mg or 13% of your daily value


In conclusion, these 9 important vitamins and minerals are essential for optimal health and performance. Incorporating a variety of nutrient-dense foods in your diet can help ensure that you get an adequate intake of these essential nutrients. Consult a healthcare professional or registered dietitian if you have any concerns about your nutrient intake or if you are considering taking supplements.

10 Surprising Benefits of MK-677 (Ibutamoren): Side Effects, Dosage, Timing (2023)

10 Surprising Benefits of MK-677: Side Effects, Dosage Review (2024)

10 Surprising Benefits of MK-677 – here is the low down with full review of the possible side effects, correct dosages and timing.

For serious athletes looking to optimise performance, MK 677 may be the answer. This popular product is a growth hormone secretagogue with powerful effects on one’s IGF-1 and GH levels – two hormones crucial for building strong muscles. Forget SARMs; you need this “secret” agent if you’re ready to take your bodybuilding game up a notch!

What is MK-677?

MK-677, also known as Ibutamoren, is a powerful growth hormone secretagogue that can help boost muscle tissue development. It has gained popularity in recent years amongst bodybuilders and gym fans for its natural ability to aid in the production of growth hormones without interfering with other biological processes.

MK-677 has been clinically studied and proven to be effective at assisting with hormone deficiencies such as reduced bone density, while at the same time providing short-term anabolic effects.  Additionally, it can also be used as a nootropic agent (a drug or supplement used to improve cognitive functioning), helping users with improved sleep and cognitive function.

How does MK-677 Work?

MK-677 works by binding to receptors in the brain that are responsible for releasing hormones like Growth Hormone (GH) and Insulin Like Growth Factor 1 (IGF-1). By doing this, it increases the body’s natural release of these hormones which help to promote healthy fat loss and muscle gain.

For those looking to build muscle or lose weight, this can prove extremely beneficial since GH helps stimulate protein synthesis and IGF-1 helps promote cell growth in muscles; leading to improved athletic performance.

Additionally, since it does not interfere with other biological processes or cause testosterone suppression – unlike other steroids – MK 677 is considered safe for long term use.

MK-677 Dosage and Timing

When taking MK 677, its 24-hour half life should be considered carefully. With an initial spike in growth hormone levels, you may find yourself feeling lethargic and drowsy further down the line. Our suggestion? Split your dose into two or take it all before bed – that way you can power through the day without sacrificing a good night’s rest!

Pumping Iron Ibutamoren (MK-677) 10mg x 60 Capsules
Pumping Iron Ibutamoren (MK-677) 10mg x 60


Read on to see the 10 Surprising Benefits of MK-677 making it the best-selling supplement today.

10 Surprising Benefits of MK-677

MK-677 has been coined the ‘fountain of youth’ – and rightfully so! This powerful compound not only aids in cultivating muscle mass and muscular strength; it can also promote overall wellbeing and cognitive function – transforming your body from the inside out. Here are 10 surprising benefits of MK-677:

1. Building Lean Muscle Mass

MK 677 has been suggested to be a powerful stimulant for muscle growth. Studies suggest it can trigger the production of two hormones which act in synergy – growth hormone and IGF-1 from your pituitary gland and liver respectively. This action could lead to an increase in strength, improved recovery time as well as positive changes on body composition (6-8lbs of extra lean mass over 6- 8 weeks based on oral doses).

A study conducted with 24 obese men revealed impressive results such as increased basal metabolic rate upon taking MK677 twice daily for 2 months.

2. Prevents Muscle Catabolism

An exciting study recently revealed that MK 677, a treatment option for reversing muscle wasting and protein loss, brought about remarkable improvements in elderly patients with hip fractures. Even more enthralling was the fact it already demonstrated success when tested on 8 food-deprived volunteers during an intensive double blind control trial – showing great promise as a viable solution to improve physical health.

3. Increases Fat Loss

Growth hormones are probably the only hormone which can help you to burn both visceral AND subcutaneous fat whilst helping you to build up lean muscle mass.

4. Improves Bone Density

Ibutamoren has shown promising evidence in the fight against bone-related conditions. It works by firstly reducing and then increasing turnover rate of bones over a period of 12 months, helping to strengthen them overall.

Studies have seen positive results when taken by obese men as well as elderly participants aged 65 years or more; all showing improved bone health and density – making it an ideal choice for treatment such as osteoporosis. Women too can benefit from this revolutionary new supplement with clinical studies reporting stronger mineral densities post-menopausal women taking MK 677 supplements!

5. Promotes Quality of Sleep

Get a good night’s sleep and gain strength even faster with MK 677, an effective nootropic that may improve both the length and quality of your REM cycle. With its neuroprotective properties supporting heightened cognitive function, take advantage of this supplement for not only better rest but improved health too!

6. Improves Hair, Skin and Nails

MK-677 can do wonders for your skin and hair – even in low doses! Studies have shown that GH has the power to revitalise your complexion whilst also strengthening the hair, skin and nails… giving you a healthier glow.

7. Promotes GH Longevity

After reaching adulthood, our bodies naturally produce less Growth Hormone (GH). To combat this shrinkage of GH levels in elderly men, researchers put 65 participants on a daily dose regimen of MK-677 – the results were staggering. These brave volunteers experienced an increase to their IGF-1 and GH numbers after only a month!

8. Improves Brain Function

MK-677 has the potential to unleash your full cognitive potential. Studies have shown that its two primary functions can drastically improve memory and learning, increase IGF-1 levels, as well as facilitate deep REM sleep – essential for optimal brain health. Take the steps towards better mental power today!

9. Prevent Growth Hormone Deficiency in Children

Studies have demonstrated that MK-677 can effectively boost key hormones in children with hormone deficiencies.

It has the potential to prevent growth issues without interfering with other important bodily functions like insulin, cortisol and thyrotropin production; making it a great treatment option for young people struggling to grow.

However, adults may not be so lucky as research found elevated levels of glucose or insulin when utilising this therapy – meaning further caution is advised before use by those over 18 years old.

10. Speeds up Recovery, Healing and Injury Repair

MK-677 promotes rapid recovery and injury repair by boosting Growth Hormone (GH) levels. This helps rebuild damaged tissues quickly, allowing athletes to get back in the game sooner than expected!

MK-677 Side Effects

MK 677 has become a popular supplement for bodybuilders, gym fanatics, and fitness buffs alike. In theory, it sounds like the perfect supplement – no testosterone suppression, no aromatization, nothing. But is MK 677 entirely safe? Let’s take a look at what you need to know about side effects and dosages before deciding if this is the right supplement for you.

Possible Side Effects of High Dosage

In completely healthy individuals, MK 677 is considered safe. The only possible side effects you may experience are muscle cramps, increased appetite and edema; these usually only crop up when you’ve taken too high a dosage of Ibutamoren. They will naturally disappear once you stop taking MK-677.

Side Effects in Healthy Individuals

When taken in recommended doses (between 10mg-25mg per day), Ibutamoren should be relatively free of side effects for healthy adults who are looking to boost their HGH levels without resorting to injections or other more risky methods such as steroids or growth hormone stimulants.

It should be noted that women tend to require smaller amounts than men due to their lower tolerance level; they should start with 5mg per day and gradually work up from there – never exceeding 25mg per day even if they feel no negative effects.

Insulin Issues in Less Healthy Individuals

Unfortunately, though it is considered safe for most people who use it correctly, those who aren’t 100% healthy may experience insulin issues. Several studies have shown that MK 677 reduces participants’ insulin sensitivity whilst raising their fasting blood glucose and blood pressure levels.

Additionally, some users have reported swollen joints, numb/tingling skin, joint pain, water retention and lethargy as a result of taking Ibutamoren MK 677. These effects are usually caused by high dosages or by those with pre-existing medical conditions taking the supplement without consulting their doctor first.


With its ability to reverse catabolism, increase lean muscle mass, improve sleep quality and cognitive functions; there are plenty of reasons why so many bodybuilders are turning towards this compound as their go-to choice when trying to achieve their desired results from the gym.

Overall, when taken correctly MK 677 can be an incredibly effective way of boosting your HGH levels without any serious side effects – but it isn’t entirely risk free either.

If you are not 100% healthy then there may be some risks associated with taking this supplement so it’s always best to speak with your doctor first before beginning any supplementation plan involving Ibutamoren MK 677 – particularly if you have existing medical conditions which could make taking this product potentially dangerous for your health.

Ultimately though – done correctly – this product can be a great way to increase your natural growth hormone levels and reap all the benefits that come along with that!

Laxogenin: A Natural Anabolic for Lean Muscle Gains

Laxogenin: 100% Natural Anabolic for Lean Muscle Gains

Laxogenin is a plant-derived (100% natural) supplement that offers a safe and non-liver-toxic method of gaining muscle mass as well as many all-round benefits to your health and wellbeing. Some of the notable benefits include building lean muscle, promoting fat loss, lowering cortisol levels and enhancing physical performance and recovery.

5 Alpha Hydroxy Laxogenin commonly referred to as “laxo” for short, has been shown to enhance protein synthesis by over 200%! It is structurally similar to ecdysterone, first discovered in Russia. Research has shown that Laxogenin exhibits similar anabolic properties to anabolic steroids such as Anavar; one of the most popular oral anabolic steroids of all time. However, unlike Anavar, Laxogenin exerts its effects without impacting your own body’s hormone levels meaning there is no suppression of testosterone or associated side effects seen with steroid use.

  • Build lean muscle mass
  • Promote fat loss
  • Enhance physical performance
  • Optimise recovery
  • Lowers the stress hormone cortisol (which causes fat storage and muscle breakdown)


Is Laxogenin Suppressive?

Laxogenin belongs to a category of plant hormones called brassinosteroids which have a similar structure to animal steroid hormones. However, plant steroids function through a completely different pathway than human steroid hormones and therefore doesn’t affect the endocrine system. It does not convert to the male sex hormones testosterone and dihydrotestosterone, nor does it convert to estrogen so you won’t need to worry about any adverse effects such as gynecomastia.

This is the highlight – this compound is completely safe for both men and women alike. The ideal supplement of choice for anyone seeking to avoid negative side effects.

Natural Muscle Building with Laxogenin

Laxogenin was first discovered in plants, from the same family that includes mustard leaves – in that form, it’s almost one of your five a day! It has some of the same properties as Anavar (or Oxandrolone), one of the most popular oral anabolic steroids of all time.

At the moment Laxogenin isn’t mainstream. That’s because most of the research that’s been done has been in the old school USSR. Word gets out though, maybe through weightlifters from back in the day – and those guys knew what they were doing.

Plant brassinosteroids and their synthetic derivatives may offer a novel therapeutic strategy for promoting growth, repair, and maintenance of skeletal muscles.

Benefits of Laxogenin

  • Accelerated recovery
  • Reduction in post-workout muscle soreness
  • Powerful anti-inflammatory effects; helps with joint pains
  • Massive pumps and vascularity
  • Faster gains in strength
  • Improved resistance to physical and mental fatigue
  • Safe for both men and women
  • 100% Natural
  • Doesn’t affect your hormones like testosterone and estrogen
  • Safe for women
  • It acts quickly and combines well with protein supplements
  • Fast-acting – ideal for anyone looking to build muscle and strength quickly
  • Can be stacked with pretty much any other compound
  • Can be used for PCT (post cycle therapy) particularly after a prohormone cycle

Supports Fat Loss

The key to what Laxogenin does isn’t totally clear, but what seems to happen is it knocks back production of cortisol, which is a stress hormone – if your cortisol levels are up you can’t grow or produce muscle. With the brakes on the cortisol, your muscles have more chance to bulk up to support your strength. One great side effect is it makes it hard to gain fat, too.

Get the Most of Your Cycle

Laxogenin can be used in many different ways to optimise results whether you’re on-cycle, off-cycle or running a PCT. Its main advantages are:

  • Stacks well with SARMs and prohormones as it doesn’t affect testosterone and estrogen
  • It’s a great alternative to prohormones if you prefer zero suppression
  • An excellent choice to add to your PCT (post cycle therapy)

Thanks to Laxogenin not messing about with your hormones, you can use it long term without hassle. We’ve seen a growing number of people use it for up to 4 months with great results building muscle, reducing body fat, boosting performance and easing mental fatigue.

Mutagenic Labz Metamorphosiz combines Laxogenin (25mg) with Epicatechin 150mg – take 2 capsules per day for best results. Take it with food for better absorption.

Cardarine GW-501516: A Complete Guide to GW501516

Cardarine GW-501516: A Helpful Guide 2019

In this article, we’ll cover everything you need to know about the PPAR-delta activator Cardarine (GW-501516), how long it takes to work, the ideal cycle length, safety and vital information you need before you consider adding it to your supplement regime.

A lot of the compounds we write about at are SARMs (selective androgen receptor modulators). This article is about something a little different, although often classed into the same category. GW501516 can help burn fat, boost metabolism, increase training endurance and protect muscle tissue but it isn’t actually a SARM. It’s a non-hormonal PPAR-delta activator which doesn’t work on the androgen capacitors at all.

If you’re curious about Cardarine, here’s everything you need to know and if we haven’t covered something, simply e-mail us and we’ll be happy to answer your questions!

Is Cardarine (GW-501516) a SARM?

As we said, Cardarine isn’t actually a SARM (anyone who tells you it is doesn’t know what they’re talking about). A SARM activates androgen receptors in muscles and other tissue. Cardarine is a PPAR-delta activator but it can produce results similar to those of SARMs.

Background Information

The best way to understand what to expect from a compound is to look at why it was developed (and what was discovered by researchers). GW501516 was originally developed by a drug company in the 1990s as a way to prevent tumours (especially on the colon and prostate). But there were some surprising discoveries.

During their studies into increased endurance and fat burning, the researchers began to understand more about the PPAR-delta pathway. They realised that activation of this pathway had an astounding impact on muscle growth, endurance and energy whilst decreasing blood lipids and subcutaneous fat. And – you guessed it – the compound GW-501516 can bind to this PPAR-delta pathway.

It turned out Cardarine could help reduce body fat, boost metabolic rate, improve the strength of blood vessels. This has a positive impact on cardiovascular health, increases muscle growth rate and even reduces recovery time. We’ll go into these factors in greater depth later in this article.

One thing we need to make clear: Cardarine is not currently sold for human consumption. It is classed as a ‘research compound’, sold for research purposes only.

How Long Does Cardarine Take to Work?

It’s important to understand how the Cardarine works in the body. Like we’ve already said, it binds to PPAR-delta in muscle cells and it stimulates certain genes which facilitate the body’s use of energy. Once you know that, you can see how it can boost your metabolic rate, improve physical performance and even help burn more fat (whilst increasing and protecting muscle mass).

You’ll notice the effects almost instantly; timing one of your dosages about thirty minutes before a high-intensity training session is an ideal protocol. The difference in energy, endurance and stamina will be noticeable almost immediately.

Burn Fat & Recover Faster with GW-501516

How exactly does Cardarine burn body fat? It’s not as simple as just torching fat right off your body. It starts with preventing the formation of fatty acids chains which, in turn, stops your body actually storing fat. This means your body needs to tap into your subcutaneous fat stores for energy – just like when you diet. But there’s one big difference to when you burn body fat by dieting. GW-501516 has those sought-after anti-catabolic properties, which means you get leaner without losing valuable muscle tissue.

What about boosting recovery between training sessions? It seems Cardarine can help your muscle fibres (specifically the slow-twitch fibres) use oxygen more efficiently, and this can help improve rates of recovery between training. It can also mean better endurance during training sessions. Good news if you train for hypertrophy, with a lower-load and higher-rep style of training.

Cardarine & Bodybuilding

You can already guess that this is an attractive compound for bodybuilders with its potential for muscle gain, training recovery and fat burning. (Side note: it’s also getting a lot of interest with the nootropics crowd.)

Cardarine could be used by itself or with other compounds as a cycle; you can stack it with prohormones, SARMs or other fat-burners. You can also use it to bridge between cycles or throughout a PCT (post cycle therapy) phase. Either way, it should be cycled for best results. Plan your cycle length for 8-12 weeks before having a 4-8 week break.

GW501516 has a half-life of 12-24 hours so you can decide whether to split your dose or to take it once per day. A dosage of 10mg-20mg per day is recommended.

Stacking Cardarine with Other Compounds

Cardarine can be used as a standalone supplement but is often stacked with other compounds. Most commonly, it has great synergistic effects with MK-677, RAD-140, Ostarine, LGD-3303 and Andarine.

It can also be used to combat negative side-effects of some anabolics (such as Trenbolone) and address potential lipid health issues. Cardarine is beneficial during PCT because it can lessen your chances of a fat-regain or rebound after running a steroid or prohormone cycle.

7 Things You Need To Know About Cardarine

#1 Fat Burner

It boosts your body’s fat-burning capacity by stimulating glucose and activating the ABCA1 and CPT1 fat-burning genes. Interestingly, there was a human study done on Cardarine’s potential for receding fatty acids, VLDL proteins and triglycerides (human studies on Cardarine are pretty rare, so it’s worth a look at this one).

#2 Training Endurance

It can stimulate the body’s glucose uptake, encouraging your body to use glucose as its primary fuel source. This means you get more energised for training and can train harder for longer. Since Cardarine can activate PPAR-delta pathways, it can also improve strength endurance. This 2015 study (on mice) suggests Cardarine can increase the specific muscle fibres associated with peak training performance.

#3 Lean Gains

It is a popular choice for stacking with SARMs and other compounds to protect lean muscle tissue whilst dieting to get shredded. As we’ve said, it can help burn body fat without the problem of losing muscle mass or looking over-dieted and scrawny.

#4 Brain Health

It can have a positive effect on blood vessels (see #5) and this means protection for your brain blood vessels (plus more blood to the brain). You might also like to know PPAR activators are thought to boost nerve cell development of nerve cells.

#5 Cardiovascular Health

It can prevent oxidative damage to blood vessels, helping reduce build-up in the arteries and (most exciting for bodybuilders) increasing your nitric oxide (NO) levels. This could mean Cardarine may reduce inflammation and associated tissue damage – a key factor in recovery and muscle growth during hypertrophy.

#6 Liver & Kidney Health

MCP-1 activity is a key factor in kidney disease and Cardarine can reduce this activity. Additionally, Cardarine acts directly on your liver (a powerhouse for storing fats for fuel in the body), using PPAR-delta activation to use fatty acids for energy. Cardarine could even reduce the body’s production of IL-6 and thereby prohibit insulin resistance.

#7 Muscle fibres

Activating PPAR-delta also means Cardarine can encourage better muscle fibre development. This means increased training endurance and the potential for greater muscle growth.

Choosing & Using Cardarine GW-501516

The bottom line is that Cardarine GW501516 is not currently legal for human consumption so it is sold for research purposes. Not for training, cutting, bulking, or bodybuilding.

You also need to bear in mind that Cardarine is banned for any tested bodybuilding competitions (yes, even trace amounts found accidentally in another product). At the moment, almost all the (limited) research on Cardarine GW501516 is on animals.

Don’t risk wasting your money on cheap, fake dupes!

One of the best selling products Mutagenic Labz Amalgamation combines a blend of GW-501516 and SR-9009, a very effective fat-loss combo. If you’re not keen on Cardarine just yet, Check out Mutagenic Labz Assimilation – our safe, legal and insanely effective GDA (Glucose Disposal Agent) to help you get leaner and build more muscle faster.

Disclaimer: By publishing this post we are not recommending using GW501516. It’s our duty to inform and educate you on all compounds. All of the information we have given here can be corroborated by published scientific reviews and literature. We recommend Mutagenic Labz Assimilation.

The Best Epicatechin Dosage for Bodybuilding (2019)

The Best Epicatechin Dosage for Bodybuilding (Updated 2023)

Wondering about the best Epicatechin dosage for bodybuilding? In the bodybuilding world, we talk about a lot of chemicals. From SARMs to prohormones, peptides and everything in between. Yet somewhere down the line after all the benefits we nearly always hear the term side effects. Well, not today guys… because epicatechin (also known as epicat) really is one of the good guys. What is it and is it really any good?

What is Epicatechin?

Epicatechin is a flavonol, a type of flavonoid found in many plants including tea, cocoa, and apples. It is a natural antioxidant and has been studied for its potential health benefits, including its effects on athletic performance and muscle growth.

What are the sources of Epicatechin?

Epicatechin is found in a variety of plant-based foods, including tea, cocoa, apples, grapes, berries, and nuts. It is most abundant in dark chocolate and cocoa products.

Benefits of Epicat

Epicatechin has been studied for its potential health benefits, which include its ability to improve cardiovascular health, reduce inflammation, and enhance athletic performance. It may also have neuroprotective properties and help prevent certain types of cancer.

Don’t let its humble origins fool you, epicat is one serious bioactive. Over the years numerous studies have proved time and time again that Epicatechin can enhance muscle growth and strength as well as improving vascularity, blood flow and stamina.

Other benefits include its ability to boost the production of nitric oxide and increasing the sensitivity of insulin. All of which adds up to promoting muscle growth and burning fat. One study has found that daily supplementation with Epicatechin also increases endurance levels.

One of its most notable features, Epicatechin has powerful antioxidant properties which mean Epicat is a natural collateral leveller and has also been linked to improved brain function and healthier hearts.

Epicatechin for Muscle Growth

Epicatechin has been shown to stimulate the production of follistatin, a protein that inhibits myostatin, a protein that limits muscle growth. This inhibition of myostatin can lead to increased muscle growth and improved athletic performance.

How does Epicat Work?

Studies suggest that epicat is a natural myostatin inhibitor. Myostatin is a protein which effectively governs the limits of muscle growth. The magic comes from follistatin which is known to affect the levels of myostatin in the body and research indicates that it increases the body’s follistatin level.
In short, epicat reduces the effectiveness of myostatin and less effective myostatin means more muscle.

Is Epicatechin safe for consumption?

Epicatechin is generally considered safe for consumption when consumed in moderate amounts through food sources. However, there is not enough research on the safety of Epicatechin supplements, and long-term use of  high epicatechin dosage may have adverse effects.

Epicatechin Dosage for Bodybuilding

It’s safe to take a decent amount of epicat and studies suggests that the most effective Epicatechin dosage ratio of 2mg per kg. The highest density of naturally concurring epicatechin comes from pure cocoa at 3mg per gram.

Obviously, it’s going to be hard to get that sort of levels just by eating chocolate, although it might be nice to try, so supplements are clearly the way to go. From previous trials, users who were taking daily epicatechin dosage between 150-200mg have reported optimum results in terms of general fitness, muscle building and endurance, which suggests that this would be the best epicatechin dosage to aim for.

How long does it take to see the effects of Epicatechin?

The effects of Epicatechin may vary depending on individual factors such as age, sex, and baseline fitness level. However, studies have shown that improvements in athletic performance and muscle growth may be observed after 2-4 weeks of supplementation.

Can Epicatechin help with Fat Loss?

Epicatechin may have some weight loss benefits due to its ability to reduce inflammation and improve cardiovascular health. However, more research is needed to determine its effectiveness in promoting weight loss.

Does Epicat Really Have No Side Effects?

Despite numerous studies and countless research projects, science has yet to directly link a single negative effect on the use of epicatechin. In fact, if anything the opposite is true. A 2007 Harvard University study demonstrated that it lowered the risk of mortality from Diabetes, Strokes, Cancer and Heart disease by 10%. Be sure to use the recommended Epicatechin dosage to avoid any potential side effects.

Epicat is Safe for Women

One of the best things about epicat is the fact that it’s beneficial for both men and women alike. Unlike so many other muscle-building supplements, it’s not hormone-based and can produce great effects regardless of chromosomes, however, it is always best to use the correct epicatechin dosage for optimal results.

Pumping Iron Epicat/Laxogenin (Natty Blend)
Pumping Iron Epicat/Laxogenin (Natty Blend)


Pumping Iron Epicat/Laxogenin (Natty Blend)

The Pumping Iron Natty Blend is a combination of Epicat and Laxogenin. The product is natural and can be used by both men and women and can also be a great product to stack during PCT to help keep hard-earned muscle gains. See our Guide To PCT for some helpful tips.

  • 100% Natural
  • Massive pumps and vascularity
  • Can be used by both men and women
  • Best-selling natural muscle builder
  • Shown to increase in protein synthesis and muscle recovery
  • Boost strength and muscle mass
  • Comparable to the effects of SARMs but without impacting your hormones
  • Powerful anti-inflammatory effects; helps with joint pains
  • Increases endurance

In conclusion

Epicatechin is the real deal. However, it is worth noting that results from Epicat won’t quite be on the same level as you’d expect from SARMs but it will certainly give you the edge you’re looking for. An organic bioactive substance that has no known side effects (if using the correct epicatechin dosage), promotes muscle, improves stamina and blood flow and has even been proven to protect against death itself… what’s not to love? Oh, and did we mention you can get it in chocolate?

Fat Burners that Actually Work

Fat Burners that Actually Work

When you want to get into the best possible shape, fat burners can give the extra edge you need when everything else is in place. If your diet, training and recovery are refined, adding a little extra something might just be the push that you need. Here we’ll take a look at how these supplements actually work, how to use them effectively and their main benefits.

Fat burners are designed to do precisely what their name suggests – target and mobilise fat cells, to burn fat more rapidly. If you’re carrying more weight than you’d like in the form of fat, these nutritional supplements increase energy expenditure and fat metabolism while impairing the absorption of fat, boosting weight loss and increasing fat oxidation while you exercise. So, let’s take a closer look at how these supplements work for your benefit.

How Do Fat Burners Work?

There are several ingredients in fat burners which will stimulate a hormonal reaction in your body to break down fat and use it as a source of fuel. They cannot work effectively on their own, however; you have to eat a healthy diet designed for bodybuilding so that the fat burner can work to its maximum effect. When you eat for fat loss, you’ll find that these supplements help your body to burn extra calories all day long.

What Are Reasonable Expectations From a Fat Burner?

Although fat burners are scientifically proven to work, it’s important to have a reasonable expectation of what these supplements can achieve. They won’t melt an enormous amount of fat every week. However, you can enhance the rate at which you lose fat. It’s considered safe to lose around 1 to 3 pounds every week. If you lose weight more quickly than this, you run the risk of losing lean muscle mass – disastrous in bodybuilding terms.

Start Out Low

Although fat burners are specifically designed to support your fat loss, taking a larger amount of them won’t give you greater results. Make sure to check out the serving guideline so you can measure out the correct dose for your needs. Start with the lowest dosage on the packaging for a couple of weeks before increasing your serving.

How To Cycle Fat Burners

No fat burner will give results continuously. When you use them over an extended period, your tolerance level will go up and they will stop working as effectively. This is why cycling your fat burner supplement is so important. Use your fat burner for around 4 to 6 weeks and then take a break for a couple of weeks before recommencing taking the supplement at a lower dose.

Optimise Your Training

When you’re using fat burners, make building muscle your priority. You need a training programme which will maximise your fat loss at the same time as minimising the amount of muscle you lose. This will ensure you maintain a healthy body composition while boosting your muscle growth.

Don’t Cut Too Many Calories

Although you should consume fewer calories than you manage to burn, going too low is always a mistake. Restricting your calorie intake won’t lead to predictable weight loss and it certainly isn’t a sustainable or healthy way to shed fat.

Take Care With Stimulants

Some fat burners contain stimulants while others do not. Products which have a high caffeine level will make you feel energetic, but they can disturb your sleep quality and that can lead to higher fat gain. It’s important to choose the right product for you, and if you drink a lot of coffee or take other stimulants, it’s usually best to choose a stimulant-free fat burner.

Our best selling stimulant-based fat burner is Yamamoto® Nutrition Ai-BURN®. This premium quality fat burner is a dietary supplement that assists a calorie-controlled diet for optimal fat loss. Thanks to its plant extracts, the product promotes a stable body weight (Green Tea) and metabolic stimulation, particularly of lipids (Bitter Orange). Moreover, cocoa extract supports metabolism and plays a tonic function.

Stimulant-Free Fat Burners

If stimulants aren’t your thing, there are non-stim options such as the MyoBlox Rubix Fat Burner. Rubix™ works on multiple facets of fat loss to aid in improved metabolism and fat utilisation without caffeine or any other stimulant. It boosts metabolism and regulates insulin levels, suppresses appetite and supports fat loss from multiple pathways.

The Olympus Labs Assassinate is another best-selling non-stimulant fat burner that helps to reduce your appetite, prevents the storage of new fat cells and stimulates your metabolism. Assass1nate also doubles as a glucose disposal agent, which helps you to utilize your food as fuel instead of storing it as fat, especially your carbs. So make sure to take it with your carb-heavy meals.

What are the Best Fat Burners?

There are a number of ingredients found in fat burners, however, SARMs have been found to be some of the most effective compounds for fat loss on the market.

Similarly, PPAR-delta activator Cardarine can boost your body’s fat-burning capacity by stimulating glucose and activating the ABCA1 and CPT1 fat-burning genes, which shows superb results such as this human study on Cardarine’s potential for receding fatty acids, VLDL proteins and triglycerides.

Another highly effective compound often used for shedding the fat is Stenabolic SR-9009. Often categorised as a SARM, Stenabolic is a REV-ERB agonist that shows a considerable boost in fat-loss and endurance.

MK-677 (Nutrobal) is also very effective for fat loss but some may suffer from an increased appetite for the first week or two, so discipline is critical.


There are many excellent fat burning supplements available to help you achieve your bodybuilding goals, but always make sure to buy from reputable online retailers to ensure that you are getting the high-quality product that you’re paying for.

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