TB-500: Injury Repair and Muscle Growth

TB-500: Injury Repair and Muscle Growth (Updated 2022)

TB-500 (Thymosin Beta-4) is a potent recovery agent with a tremendous ability to enhance up injury repair and recovery, however, its many benefits also include growth of muscle mass and improved performance. TB-500 is naturally produced in the body, in higher concentration at the site of tissue damage and supports the production of new blood and muscle cells.

It also has incredibly powerful anti-inflammatory effects which can oftentimes offer instant pain relief. Its powerful healing effects have been identified specifically in the tendons, ligaments, muscle, skin, heart and eyes.

Before you read any further you should know that this peptide is banned in almost all competitive sports and events. Also, while it is readily available, Thymosin Beta-4 (also known as TB-500) is sold for research purposes only, not for human consumption.

Benefits of TB-500

  • Increases muscle growth
  • Increases endurance and stamina levels
  • Decreases inflammation in joints
  • Promotes hair growth
  • Rapid healing of wounds
  • Repair of tendons and ligaments
  • Improved flexibility of joints
  • Promotes the regeneration of blood vessels
  • Repairs damaged heart tissue following a heart attack
  • Heals ulcers and lesions (including stomach and intestinal ulcers)
  • Protects and restores neurons after brain injury

What is TB-500?

TB-500 is a synthesised peptide, essentially a short-chain version of the naturally occurring Thymosin Beta-4. It has not been used to treat humans in any tangible method but although it is not considered a veterinary-specific drug, it is often used in the treatment of horses and occasionally dogs.

As there’s little research on human trials we can only go on what we’ve heard and data compiled from various veterinary trials. Its properties are similar to those of HGH and results also appear similar.

Users report increased strength, muscle growth, enhanced recovery and relief from chronic and severe pain as well as improved endurance. There are also reports of increased hair growth, better condition hair and even a lessening of grey hair.

How does TB-500 Work?

In simple terms, TB-500 boosts your body’s protein efficiency. This means that the functions of those proteins are dramatically improved. It increases red blood cell production and improves metabolism and essentially supercharges your body’s ability to grow new cells.

Additionally, thanks to its molecular composition TB-500 is remarkably light and can, therefore, race your system finding areas to improve. It is this that makes it particularly good when it comes to targeting inflammation and pain.

How to Use TB-500

TB-500 is taken as any other peptides; you’ll need to reconstitute it before injecting the solution either subcutaneously or intramuscularly. To take SubQ, find an area of fatty tissue, the abdomen is good but avoid the navel vicinity.

Next, simply clean your hands, wipe the area with a sterile swab, pinch the area with your fingers and then inject your prepared syringe. To take intramuscularly, locate an area of muscular tissue, usually one where you are experiencing pain, and jab the syringe deep into the muscle tissue. It can be a difficult and painful process, but the rewards should outweigh the trouble.

TB-500 Dosage

The dosage depends on the purpose you are using it for, and/or the type of injury or damage that you need to treat. A general guideline would be between 4-8mg of TB-500 per week for the initial loading phase of 4 to 6 weeks, followed by 2-6mg every 2 weeks to maintain its effects. The effects wear off within 2-3 weeks of injection.

Loading phase:

      • Duration: 4-6 weeks
      • Dosage: 4-8mg of TB-500 per week
      • Frequency: 2mg per injection, between 2-4 times per week (depending on the total dosage you choose)

Maintenance phase:

    • Duration: as long as you need
    • Dosage: 2-6mg of TB-500 every 2 weeks
    • Frequency: 2mg per injection, between 2-3 times every 2 weeks (depending on the total 2-week dosage you choose)

Side Effects

The most common side-effect that has been reported by bodybuilders who use this peptide is that of lethargy and possible headaches. Some report experiencing a head rush immediately after injecting it, although this shouldn’t last longer than a minute.

We lack a lot of data on TB-500 but we do know that the medical community is divided over whether or not it has been linked to cancer; some say it increased the rate at which cancer cells grow, while others suggest it may actually promote white blood cells with which to fight it.

Combine TB-500 and BPC-157 for Healing Injury and Repair

BPC-157 and TB-500, which both stimulate wound healing via various biological mechanisms, have synergistic effects when used together. Clinically developed to boost maximum recovery as well as healing together with adjustability, joint flexibility, and also protection against injury.

BPC stands for Body Protective Compound, and that is exactly its function. It was originally discovered to be a protective peptide within our gut and to have a healing effect in both our upper and lower GI tract.

It should be understood that BPC 157 is only a small part of the whole BPC protein, but it is essential for its functionality because it is where binding spots for enzymes are located. The structure of this stable gastric pentadecapeptide consists of 15 amino acids, and looks a little something like this: Gly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val.[1]

Benefits of BPC-157

Some of the world’s top researchers around the worldare working to determine whether BPC 157 contains life-changing properties.

The list of benefits is growing by the day:

  • Useful adjunct to healing almost anything related to the GI tract
  • Heals mitochondrial damage
  • Accelerated healing of ligaments, bones, and tendons
  • Reduces inflammation in autoimmune conditions like rheumatoid arthritis,
  • Protects endothelium and the formation of scar tissue
  • Improves brain health & mood
  • Blocks long term effects of corticosteroid injections
  • Stabilized production of certain hormones and neurotransmitters (eg. serotonin)
  • Protection of the cardiovascular system
  • Reduced drug-induced damage
  • Better general body repair and wound healing
  • Improved body’s response to allergens and viruses

Researcher Ben Greenfield has written extensively about both of them, featuring them in his new book Boundless.

“I’ve personally used peptides BPC-157 and TB-500 to enhance healing and recovery.

“…BPC-157 also accelerates wound healing and, via interaction with the nitric oxide system, protects endothelial tissue and builds blood vessels”

“…TB-500 can be injected in or near any damaged muscle site and sore or injured joint with surprising healing effects”

The similarities between TB-500 and BPC-157

The main similarities between TB-500 and BPC-157 are as follows:

  • Both research peptides have demonstrated anti-inflammatory properties
  • Both research peptides promote angiogenesis (i.e. the formation of new blood vessels)
  • Some researchers contend that TB-500 and BPC-157 increase blood circulation by different mechanisms, but the end result is the same

The differences between TB-500 and BPC-157

There are some obvious differences between these two research peptides.

  • TB-500 has a systemic effect, which means it works regardless of where the injection is made
  • BPC-157 has a localized effect and must be injected near the site of the injury
  • TB-500 works to distribute actin, whereas BPC-157 is directly responsible for increasing actin production.

Keep in mind that the only way to definitively prove the difference between TB-500 and BPC-157 would be to conduct a large-scale clinical trial in which the same type of injury is being treated.

While this type of research has yet to be conducted, it is clear that BPC-157 and TB-500 do not counteract one another.

If anything, anecdotal evidence shows that they work synergistically to speed up the healing process and further accelerate the rate of recovery.

Recommended Dosage for TB-500 and BPC-157

When it comes to TB-500 vs. BPC-157, researchers should know that these research peptides have no safe or recommended dosage.

However, past studies indicate that researchers have dosed them accordingly in the past:

  • BPC-157: 250 mcg injected intramuscularly, daily – once in the morning on an empty stomach and once again right before bed
  • TB-500: 2-4 mg injected intramuscularly, twice a week in evenly spaced doses (ex. Monday and Thursday)

Cycle length is very individual and can vary depending on the specific requirements of the research subject.

Injury Repair & Recovery Stack (MK-677, BPC-157, TB-500)

The Injury Repair & Recovery Stack combines three of the best healing compounds on the market; MK-677, BPC-157 and TB-500. These compounds stimulate wound healing via various biological mechanisms and have synergistic effects when used together. Clinically developed to boost maximum recovery as well as healing together with adjustability, joint flexibility, and also protection against injury.

Pumping Iron Injury Repair & Recovery Stack
Pumping Iron Injury Repair & Recovery Stack
bodybuilder steroids supplements prohormones pct guide

PCT: A Guide to Post Cycle Therapy (Updated 2022)

Post-Cycle Therapy, or PCT for short, is essentially the process of levelling your body’s hormone levels after a SARMs, steroid or prohormone cycle. Simply put, your body may cease to produce or at least lower your natural hormone production when subjected to significantly raised levels of exogenous substances.

To run the most effective PCT, there are 5 goals we want to achieve:

  1. To restart HPTA
  2. Prevent catabolism as our cortisol level rises
  3. Prevent fat gain while retaining enough calories to maintain the muscle
  4. Minimise the loss of strength
  5. To balance our hormones in order to reduce potential negative effects

HPTA Restart Protocol

Restarting the HPTA has been covered many times, a quick evolutionary search on SERMs and you will find many articles relating to the use of both Clomid and Nolvadex, these can be combined together or used solo. To restart HPTA Clomid is a solid choice but you can also use Nolvadex. Both are effective in aiding recovery.

Ostarine Prevents Catabolism During PCT

At this transition point, your body will quickly begin to produce testosterone. It’s here you must be careful not to allow excess cortisol from chewing up your hard-earned muscle. At the same time, your body will have little to no nitrogen which will cause your muscles to crave nutrients that you don’t have.

To counter these effects, prevent catabolism and lessen the amount of muscle loss, a sensible solution is to introduce a non-suppressive anabolic; and this is the greatest opportunity for SARMs to really shine. A low dose at 10mg of Ostarine (MK-2866) will help preserve your muscle gain and increase your nitrogen and IGF levels. This will also help you continue smashing your workouts and even improve muscle pumps.

Cardarine Prevents Fat Gain During PCT

After you’ve dealt with your cortisol levels, you’ll find that the excess testosterone binds with it, rendering it inactive. To prevent fat gain yet keeping your calories up requires a PPAR modulator such as Cardarine (GW-50156). This will regulate the rate at which you burn fat. It does this in a number of ways but essentially it promotes glycogen retention in muscle tissue. This allows the body to alter its metabolism and increase the amount of fat burned instead of using carbs or protein as fuel.

This is a true win/win and means your body retains muscles and yet fat retention is reduced. This, in turn, will give you more stamina and can have the added bonus of reducing cravings.

Balancing Your Hormones During PCT

The drawback to most PCT is the potentially negative side effects. To counter these you need to ensure you keep your hormones balanced. As testosterone levels rise, estrogen levels are also significantly increased and sometimes at a faster rate. Estrogen flooding causes skin problems and can even cause gynecomastia (swelling of the nipples).

To counteract this, Aromasin can be used to inhibit aromatase whilst only increasing your IGF levels by approximately 30%. Aromasin will also prevent estrogen rebound and therefore save you from developing man-boobs. Taken on alternate days, a 12.5mgs dose of Aromasin is great for PCT. It helps up your testosterone levels by actually lowering estrogen.

Benefits of an Aromatase Inhibitor

Although some supplements and SARMs do not convert to estrogen, you will still get the odd one or two guys who experience estrogen-related side effects during their cycle. In such cases, a mild over-the-counter PCT supplement with an aromatase inhibitor is ideal. Mild suppression of testosterone will throw your estrogen levels out of balance and therefore can cause side effects in those who are more prone.

The extent of these side effects will always depend on several factors:

  • Which compound you are using
  • The dose
  • The length of your cycle
  • Your individual predisposition to suppression

For most prohormones and SARMs, your best solution is Arimistane or 6-OXO.

What is 6-OXO?

6-Oxo in Pumping Iron Pro PCT is used to block the conversion of testosterone to estradiol. When the body has more testosterone, the anabolic potential is significantly increased. This will help to build more lean muscle and increase overall body strength.

By having more testosterone, not only will you have increased muscle mass but there is a greater capacity to decrease body fat. Favourable testosterone to estrogen ratio is critical for achieving optimal body composition.

Pumping Iron Pro PCT (6-OXO)
Pumping Iron Pro PCT (6-OXO)

 

  • 6-OXO is the strongest legal aromatase inhibitor on the market
  • Increases lean muscle mass
  • Reduces conversion of testosterone to estradiol
  • Supports muscle retention
  • Increases testosterone:estrogen ratio

What is Arimistane?

Arimistane is a powerful Aromatase Inhibitor (AI) and cortisol blocker that effectively reduces circulating levels of estrogen in the body. It acts as a suicide inhibitor to decrease the number of androgens in the body that can change to estrogen.

Arimistane is a great compound to use for PCT after a prohormone cycle as it increases testosterone whilst lowering estrogen levels. This also means it’s an effective natural muscle builder so you can expect a noticeable increase in muscle growth, strength, muscle hardness and definition.

Enhanced Athlete Arim-RX
Enhanced Athlete Arim-RX

 

  • Blocks high levels of estrogen and cortisol
  • Increases testosterone levels
  • Increases muscle mass
  • Reduces fat storage
  • Improves recovery
  • Improves vascularity
  • Drying and muscle hardening effect
  • Boosts libido

What is Blue Ox?

Enhanced Labs Blue Ox is a natural test booster supplement for men that supports a balanced mood and optimal strength. Blue Ox is often stacked alongside more potent PCT compounds.

Whether you’re off-cycle or just pure natty, our Blue Ox booster is chock-full of essential ingredients that excel in boosting virility and libido.

  • 120 Capsules
  • PCT Regeneration
  • Boost strength and muscle
  • Maintain muscle mass between cycles
  • Increase libido and sexual performance
  • Support healthy energy levels
  • Mood support

 

Enhanced Athlete Blue Ox Test Booster
Enhanced Athlete Blue Ox Test Booster

 

  • Clinically formulated to naturally elevate testosterone levels
  • Contains 9 naturally derived pharmaceutical grade ingredients to increase the body’s own natural testosterone production through multiple different pathways
  • Contains natural anti-estrogen ingredients to regulate estrogen production and remove the metabolites that can cause health concerns like water retention and gynecomastia
  • All of the ingredients in Blue OX have been scientifically verified in human studies

How to do a SARMs PCT

PCT protocol is a highly debated and subjective matter depending on the individual so we can’t advise you on what you should/shouldn’t do but we can give you some guidance. In general, a person cannot be sure which option is best for them unless they do blood tests before and post cycle. Every individual is different and the many factors that will affect your requirements include:

  • Your starting point/baseline
  • Any previous supplement/cycle history
  • Your predisposition/genetics
  • Your age
  • Which compound(s) you are using
  • The dosage(s)
  • The length of your cycle
  • How your body reacts to the compound(s)
  • Side effects encountered – if any

There are some options you can look at:

  1. Aromatase Inhibitor: Suitable for Ostarine and (for some people) potentially other SARMs (such as LGD-4033, LGD-3303, S-4), and/or shorter cycles up to 8 weeks): A mild over-the-counter PCT stack that includes an aromatase inhibitor (Arimistane) such as Arim-RX combined with a high-quality natural testosterone booster such as Blue Ox.
  2. SERMs: For potent compounds (such as RAD-140, YK-11, S-23), advanced stacks and long cycles: A full PCT which includes a SERM (selective estrogen receptor modulator, not to be confused with SARMs), such as Nolvadex and Clomid.
  3. 6-OXO – A very potent aromatase inhibitor that is effective for most people and most compounds including prohormones and SARMs, often combined with a natural testosterone booster such as Blue Ox.

A SERMs PCT protocol for an advanced cycle may look like:

  • Nolvadex (Weeks 1-4): 40mg/40mg/20mg/20mg
  • or Clomid (Weeks 1-4): 50mg/50mg/25mg/25mg

Preparation is key. One thing we can recommend is always having both options on hand in case you find that you need to run a full PCT, even if you haven’t anticipated this possibility.

A proper PCT is equally as important as your cycle. Don’t wait until near the end of your cycle to find the products that you need.

You can also make a judgement on the signs of testosterone suppression if you experience any of these (low energy, low libido, sadness, loss of strength and motivation, chronically poor performance in the gym) after finishing the cycle which will give you an idea of how suppressed you are. This also applies after you complete your PCT to assess the indicators of a successful PCT. Always ensure to take enough time off between cycles to ensure adequate recovery; listen to your body and if in doubt, take more time off.

Read more about Bridging Prohormone Cycles with SARMs to get the most out of your PCT protocol.

Laxogenin: A Natural Anabolic for Lean Muscle Gains

Laxogenin: 100% Natural Anabolic for Lean Muscle Gains

Laxogenin is a plant-derived (100% natural) supplement that offers a safe and non-liver-toxic method of gaining muscle mass as well as many all-round benefits to your health and wellbeing. Some of the notable benefits include building lean muscle, promoting fat loss, lowering cortisol levels and enhancing physical performance and recovery.

5 Alpha Hydroxy Laxogenin commonly referred to as “laxo” for short, has been shown to enhance protein synthesis by over 200%! It is structurally similar to ecdysterone, first discovered in Russia. Research has shown that Laxogenin exhibits similar anabolic properties to anabolic steroids such as Anavar; one of the most popular oral anabolic steroids of all time. However, unlike Anavar, Laxogenin exerts its effects without impacting your own body’s hormone levels meaning there is no suppression of testosterone or associated side effects seen with steroid use.

  • Build lean muscle mass
  • Promote fat loss
  • Enhance physical performance
  • Optimise recovery
  • Lowers the stress hormone cortisol (which causes fat storage and muscle breakdown)

 

Is Laxogenin Suppressive?

Laxogenin belongs to a category of plant hormones called brassinosteroids which have a similar structure to animal steroid hormones. However, plant steroids function through a completely different pathway than human steroid hormones and therefore doesn’t affect the endocrine system. It does not convert to the male sex hormones testosterone and dihydrotestosterone, nor does it convert to estrogen so you won’t need to worry about any adverse effects such as gynecomastia.

This is the highlight – this compound is completely safe for both men and women alike. The ideal supplement of choice for anyone seeking to avoid negative side effects.

Natural Muscle Building with Laxogenin

Laxogenin was first discovered in plants, from the same family that includes mustard leaves – in that form, it’s almost one of your five a day! It has some of the same properties as Anavar (or Oxandrolone), one of the most popular oral anabolic steroids of all time.

At the moment Laxogenin isn’t mainstream. That’s because most of the research that’s been done has been in the old school USSR. Word gets out though, maybe through weightlifters from back in the day – and those guys knew what they were doing.

Plant brassinosteroids and their synthetic derivatives may offer a novel therapeutic strategy for promoting growth, repair, and maintenance of skeletal muscles.

Benefits of Laxogenin

  • Accelerated recovery
  • Reduction in post-workout muscle soreness
  • Powerful anti-inflammatory effects; helps with joint pains
  • Massive pumps and vascularity
  • Faster gains in strength
  • Improved resistance to physical and mental fatigue
  • Safe for both men and women
  • 100% Natural
  • Doesn’t affect your hormones like testosterone and estrogen
  • Safe for women
  • It acts quickly and combines well with protein supplements
  • Fast-acting – ideal for anyone looking to build muscle and strength quickly
  • Can be stacked with pretty much any other compound
  • Can be used for PCT (post cycle therapy) particularly after a prohormone cycle

Supports Fat Loss

The key to what Laxogenin does isn’t totally clear, but what seems to happen is it knocks back production of cortisol, which is a stress hormone – if your cortisol levels are up you can’t grow or produce muscle. With the brakes on the cortisol, your muscles have more chance to bulk up to support your strength. One great side effect is it makes it hard to gain fat, too.

Get the Most of Your Cycle

Laxogenin can be used in many different ways to optimise results whether you’re on-cycle, off-cycle or running a PCT. Its main advantages are:

  • Stacks well with SARMs and prohormones as it doesn’t affect testosterone and estrogen
  • It’s a great alternative to prohormones if you prefer zero suppression
  • An excellent choice to add to your PCT (post cycle therapy)

Thanks to Laxogenin not messing about with your hormones, you can use it long term without hassle. We’ve seen a growing number of people use it for up to 4 months with great results building muscle, reducing body fat, boosting performance and easing mental fatigue.

Mutagenic Labz Metamorphosiz combines Laxogenin (25mg) with Epicatechin 150mg – take 2 capsules per day for best results. Take it with food for better absorption.

Best Dosage for MK 677: Ultimate Guide for Mega Mass

Best Dosage for MK 677: Ultimate Guide 2021

Discover the reason this compound has been making waves in the bodybuilding industry but most important of all, the best dosage for MK 677.

MK-677 also known as Ibutamoren is a ground-breaking compound often classed into the same category as SARMs, although technically it isn’t actually a SARM. MK677 is a growth hormone secretagogue which essentially elevates your own natural production of growth hormone which has a whole host of health and fitness benefits all-round.

Not only does Ibutamoren improve recovery, muscle mass and fat loss, it even has remarkable anti-ageing properties as well as improving skin texture, hair and nails.

People are getting great results using MK-677 but obviously their results depend on a lot of factors including how they research it and their commitment to diet, training and recovery.

Although there is plenty of information about MK-677, we cover the different ways in which it can be researched and the best dosage for MK 677 for different purposes.

What is MK-677?

MK-677 is a growth hormone secretagogue – basically, it is a compound that encourages the body to secrete more growth hormone. Now you already know that growth hormone (GH) is a powerful hormone which is highly anabolic, helping you to grow new tissue (including muscle tissue) and retain more lean muscle when you are dieting or training hard.

Like most SARMs and similar compounds, MK 677 started life as a manmade compound developed as a potential medical aid. In this case, it was developed and studied as a possible alternative for patients with hormonal deficiencies and problems related to a lack of bone density.

Early studies suggested MK 677 could reverse catabolism (tissue breakdown) to boost bone density and the density of other tissues including muscle. It was also found to aid sleep and mental function in some study subjects.

Most notably – for us, anyway – MK 677 could boost the body’s production of growth hormone but without suppressing any of the natural hormonal biological processes. This meant much fewer side effects than anabolic steroids.

How Does MK 677 Work For Muscle Gain?

Although MK 677 isn’t a SARM, it really can help you boost muscle mass, strength, and density if you are already training well in the gym. It does this by encouraging your body to secrete higher levels of two key anabolic hormones: growth hormone (GH) and growth factors (IGF-1).

How? By imitating the hormone ghrelin (which stimulates appetite) and binding to ghrelin receptors. This has a number of beneficial knock-on effects including cognitive strength, better mood, a healthier appetite and gains!

One important thing to know is MK 677 doesn’t impact your body’s natural hormone levels (like anabolics tend to do), so you won’t need to do a PCT (post cycle therapy) if you use MK 677.

7 Benefits of MK-677

Here are the top 7 benefits for bodybuilders and strength athletes.

1 Build muscle mass

MK 677 can help your body pack on muscle mass by encouraging more growth hormone and IGF-1. These are two highly anabolic hormones which support better MPS (muscle protein synthesis), increase nitrogen retention, and boost your strength.

2 Minimise catabolism, retain muscle mass when dieting

MK 677 can also reduce muscle loss, which is a real problem when dieting for fat loss. The more muscle you can retain, the better you will look when you are lean. Think that full, dense look rather than a scrawny over-dieted look!

3 Faster fat loss

The anabolic hormones we already mentioned (GH and IGF-1) can actually help you torch through body fat, making MK 677 a useful compound for dieting or recouping. Just remember, you can’t use it if you are entering a tested competition as it is banned under WADA rules.

4 Increased bone density

Bone density might not sound like a priority for bodybuilders, but it should be. After all, what do you think is the foundational structure for all that muscle mass? Your skeleton. A healthy, strong skeleton means you can lift heavier and put more stress through your joints, ultimately meaning you can build more muscle – and keep training later into life.

5 Improved training recovery

Deep restful sleep and the ability to recover between training sessions are key components of optimal recovery. MK-677 has neuroprotective benefits, meaning you are more likely to have a great night’s sleep with plenty of REM sleep (key for recovery). As you know, good sleep means better training motivation, more energy, better performance in the gym and even the ability to stay away from junk food and snacks!

6 Skin condition and tightness

Any competitive bodybuilder will tell you that skin condition is a real bonus. Great skin makes muscles look even better. Even low doses of MK 677 can have a positive impact on skin cells, helping you look full and healthy.

7 Mood, focus, and training motivation

MK 677 can boost your brain function, helping you feel better and perform better. This means more energy and better focus for the gym as well as a better overall outlook – all of which will help you stick to your training and diet programme.

Understand The Side Effects Of MK 677

Now, you must understand that MK 677 is a manmade compound which was first developed as a possible medication. Therefore – like most medications – it can have side effects. The chance of these is greatly heightened if you incorrectly dose MK 677 which is why we’ve written this article about the best dosage for MK 677.

The good news is that MK 677 shouldn’t suppress your natural testosterone levels if you are otherwise healthy. So you won’t need to run a PCT.

  • Muscle cramps – you may experience some mild muscle cramps using MK 677
  • Bigger appetite – this is quite likely at higher dosages as MK 677 stimulates ghrelin
  • Water retention – this can happen at the start of a cycle but tends to subside after 2-3 weeks
  • Reduced insulin sensitivity – may occur if you are not completely healthy
  • Increased blood pressure – only likely in unhealthy individuals

In short, we advise you to always exercise caution with any compound. If in doubt, do not use it. Know the risks, do your research, and make an informed decision.

Best Dosage for MK 677

The first thing to mention is that MK-677 has a half-life of 24 hours, which means you can take it just once per day but some people do prefer to split the dosage.

As MK 677 can spike GH levels, some people find this makes them feel tired. Anecdotally, some people have found that splitting the dosage can help to reduce some side effects such as fatigue.

The options are:

  • Split your dose in two, take one during the day and one before bed
  • Take your daily dose in one go, before bed
  • Tkae your daily dose in one go, upon waking

The best dosage for MK 677 will depend on your goals and the main purpose of your research. This compound has benefits even at low doses, so there is absolutely no need to take high doses, contrary to popular belief.

Always start with the lowest dosage (usually half of your final dosage) for the first week to assess your response.

MK-677 is a long-term compound that will take a few weeks to see results because MK 677 is manipulating your natural GH levels. Results will take time to appear to the eye but will be sustainable, quality results.

Dosage for MK 677 (Gaining Mass and Boosting Fat Loss)

The best dosage for MK 677 when looking to gain muscle mass and lose body fat is between 20-25mg per day.

Some users have reported better results at higher doses of around the 25mg range buta higher dosage will also tend to exhibit more pronounced appetite and lethargy. Lowering the dosage and finding what works best for you is always the best protocol.

This 1998 double-blind, randomised human study shows impressive results in a group of males given Ibutamoren MK-677 – they showed increased lean mass, GH secretion, and even energy expenditure in just two months. That same study showed that serum IGF-I increased by approximately 40% with Ibutamoren MK-677 treatment.

See our MK-677 Before and After Photos.

Dosage for MK 677 (Anti-Ageing, Recovery, Injury Repair, Healing)

Ibutamoren works well at lower doses. The average is around 5mg and this is enough to produce numerous GH pulses over the course of a day. For anti-ageing and recovery, the best dosage for MK 677 is as low as 5-10mg per day, maintained long-term.

Along with benefits to bone health, MK-677 is renowned for its anti-ageing properties because HGH helps to promote growth and recovery in older cells.

Coupled with the anti-inflammatory effects of IGF-1, will help to promote cell health and prevent breakdown. Furthermore, higher IGF-1 levels also help to maintain brain development.

Does MK-677 Require a PCT?

Stenabolic (SR-9009) is not suppressive and does not generally require a PCT.

5 amazing benefits of ostarine mk-2866

5 Surprising Benefits of Ostarine MK-2866

Discover everything you need to know about the popular SARM Ostarine, also known as MK-2866. Ostarine is one of the most popular SARMs in the bodybuilding and physique world – no surprise once you learn about the potential effects of this research-backed compound.

What Is Ostarine?

If you’ve been around the bodybuilding or physique sport world for even a short while, you’ve probably heard about Ostarine. But what is this compound, why do some people use it, and should you consider it (or should you look for a better alternative)? To begin, it’s worth mentioning that this is widely considered one of the safest anabolic SARMs on the market.

MK-2866 is a SARM (Selective Androgen Receptor Modulator) which is popular with strength, power and physique athletes who are looking for ways to boost muscle mass and strength with fewer or no side effects compared to harsher compounds such as steroids or prohormones. It was originally developed to help treat muscle-wasting conditions, so you can understand why bodybuilders are drawn to it. It preserves lean tissue when conditions would usually lead to catabolism (for example, dieting or high-frequency training).

How Does MK-2866 Work?

Like any SARM, MK-2866 can mimic testosterone (the primary anabolic hormone), stimulates the body’s androgen receptors and boosts the steroid hormone receptors. It can activate stem cells, helping to regenerate and build muscle and bone tissue – exactly what bodybuilders want. For this reason, MK-2866 is thought to have fewer side-effects than anabolic steroids because SARMs do not affect the organs. They are very selective by their very nature, which is the main advantage of any SARM. Of course, this can change if someone stacks Ostarine with an anabolic steroid.

Ostarine is renowned for improving both training performance (strength and power) and physique appearance (through bigger, denser muscle mass). However, its noteworthy advantage is injury repair and recovery; it has an excellent affinity for joint repair in particular.

Muscle Gain & Recovery with MK-2866

One reason many bodybuilders use MK-2866 is for its impact on the IGF-1 gene, as well as muscle cells and cells in connective tissues. Ostarine may stimulate these cells which means faster recovery from training stress. Less time out for recovery (or less soreness during your next training session) means you can train more frequently, achieving a greater workload across the training week. This is likely to result in greater muscle growth from the training stimulus.

In one human study of 120 healthy elderly people, Ostarine significantly increased lean muscle mass as well as fitness levels with no side effects or steroid-like risks.

5 Potential Effects Of Ostarine

There are five key reasons a bodybuilder might choose to use Ostarine.

#1 Muscle gain
The SARM is often used as a compound to aid muscle gain because of its effect on stimulating muscle cells. Not only does this mean you may gain additional muscle tissue but you are likely to protect the muscle mass you already have (important during a fat loss phase).

#2 Recovery
It can mean faster recovery from DOMS and training fatigue. This means you can train more frequently and you can push harder during each session.

#3 Fat loss
It is thought to slow or stop muscle breakdown (catabolism) whilst the body is getting leaner. This means you can push harder during a dieting phase without the usual worry about losing muscle, resulting in the holy grail of lean gains.

#4 Cardiovascular health
Ostarine can have a number of benefits for heart health, including reduction of triglycerides, reduced lipids and reduced total cholesterol. It may also help lower blood glucose levels and improve insulin resistance.

#5 Increased metabolic rate
It is thought to increase base metabolic rate, meaning you will burn more calories during training, NEAT and cardio. It can also increase endurance and give you better stamina, which will also mean longer more intense training sessions. All these combined means you are likely to burn more calories – good news if you are trying to get shredded.

How Long Does MK-2866 Take to Work?

As with most supplements, one of the most commons questions asked is how long MK-2866 takes to work. Anecdotal evidence shows that people tend to feel a great sense of ‘wellbeing’ within 2-3 days of using Ostarine. A sense of vitality, positive mood, good energy and holistic ‘balance’.

Many bodybuilders and athletes report noticeable consistent strength gains within the first 2-3 weeks of using the compound. In terms of physical changes; body composition and muscle definition, results will usually be seen to the eye from 4 weeks onwards, however, it’s important to understand that this ultimately comes down to so many individual factors. Your current body composition, your goals, your training and diet, as well as recovery protocols. Everyone will respond to different compounds in different ways whilst your efforts and commitment will play an even bigger part in how quickly you see results.

Ostarine & Bodybuilding

MK-2866 is best known for is building muscle and burning fat – two things all bodybuilders are interested in at some point during their lifting career (even if they never want to step on stage).

Muscle gain: remember how we said Ostarine was originally developed to help tackle muscle wasting diseases? People who want to build more muscle tissue, and hang on to the muscle they’ve got, can use MK-2866 to harness those anti-catabolic effects.

Fat burning: Ostarine has muscle preserving properties, meaning you can diet more aggressively or for longer without losing muscle tissue. Retaining muscle during a diet phase means you’ll also retain more strength, so you can train harder and heavier, all leading to a positive circle of lean gains.

But there’s more than muscle building and boosted fat-burning abilities. Ostarine can also boost bone health, help reduce LDL and triglycerides and improve insulin resistance. These are all things which can be attractive to bodybuilders looking to gain mass and strength.

How to Stack Ostarine

Bodybuilders use Ostarine in a few different ways. This is what you need to know.

Using Ostrarine by itself: Ostarine MK-2866 can be used alone. It should be used as a cycle (like any SARM) of 12 weeks for men, up to 8 weeks for women. Men should use between 15-25mg and women should use 5-10mg. Ostarine has a half-life of 24 hours so there is no need to split the dose across the day.

With other SARMs: bodybuilders typically stack Ostarine with other popular SARMs, like Ibutamoren MK677 or Ligandrol LGD-4033. Ostarine can also be used in a so-called “triple SARM” stack of Ostarine plus Andarine and Cardarine (although Cardarine isn’t a true SARM).

Choose The Best Ostarine Supplement

Like any SARM, it’s important you choose the best-quality Ostarine MK-2866 supplement. Don’t go for the cheapest product. Check the label carefully and look for smart ingredients which are designed to optimise the product’s effectiveness so you see the best gains.

We love our best selling Mutagenic Labz Ostagainz, which delivers 10mg of pure Ostarine MK-2866 along with Piperine in every dose (to aid digestion and absorption). It’s non-liver-toxic, has no androgenic activity, and promises minimal side effects – with maximum results. Click here to try it for yourself. Choose an Ostarine product you can trust, backed by a reliable name in bodybuilding supplements.

We should point out that Ostarine – like all SARMs – is not approved for use in tested strength and physique sports but for those of you who don’t want to compete with the tested federations? There are so many reasons to try Ostarine by itself or as a stack, whether you’re dieting, bulking, or aiming for a body recomposition phase.

Everything You Need To Know About MK-677

MK-677 (Ibutamoren) – What You Need to Know

Also known as Ibutamoren, MK-677 is often referred to as part of the SARM family, although strictly speaking this is incorrect. Ibutamoren is not a selective androgen receptor modulator but is a compound known as a secretagogue. What this means is that it signals the body to produce or secrete a specific hormone.

Benefits of MK-677

MK-677 makes the body increase the amount of growth hormone it produces, which has many ancillary effects, most of which are related to muscle growth and increased bone density. In medical fields, it was developed to treat frailty in the elderly. In short, the main benefits of ibutamoren are:

  • Increases IGF-1 and growth hormone serum levels
  • Promotes lean muscle mass gain
  • Increases fat oxidation
  • Boosts recovery and healing including bones, tendons, and ligaments
  • Tightens the skin
  • Improves sleep quality

In addition to increases in muscle tissue and a leaner physique, studies suggest that Ibutamoren can produce significant anti-ageing effects, as well as improved bone density and more rapid recovery times.

A single tablet taken daily is designed to release wave after wave of naturally secreted growth hormones.

How Does MK-677 Work?

Ibutamoren is an orally taken drug which once ingested tricks the pituitary gland into working overdrive. The massive boost in GH or growth hormone is what makes it so interesting to the bodybuilding world. Combined with the appropriate diet and exercise regimen, an introduction of Ibutamoren can cause impressive muscle growth alongside much improved fat loss.

Side Effects of MK-677

It’s always worth considering the data when trying to determine whether a drug is right for you. While there has been a reasonable amount of study into Ibutamoren, there hasn’t been a great deal of research into its use as a bodybuilding supplement. With that said, the studies and anecdotal evidence that do exist suggest there is little to fear health-wise.

The most common side-effects experienced with Ibutamoren include slight lethargy, some experience increased appetite, although this isn’t always a negative side-effect for those who need some help gaining weight/bulking.

Although rare, some users have reported headaches and nausea, which would appear to increase in prominence at higher doses.

Because Ibutamoren is an orally taken substance, it’s probably safer than anything you need to take via a needle, which also reduces any hygiene-related risks such as bacteria or infections from unclean syringes or contaminated solutions.

MK-677 is Safe for Women

Ibutamoren is fine to use for both men and women as it doesn’t affect the amount of testosterone or estrogen the body produces. This means that there is zero-risk of specific hormonal imbalances and unwanted side-effects like puffy nipples, heightened aggression or hair loss.

MK-677 Dosage

Ibutamoren works well at lower doses. The average is around 5mg and this is enough to produce numerous GH pulses over the course of a day.

Some users have reported more pronounced effects at higher doses of around the 25mg range, but there is significant anecdotal evidence to suggest a higher dose comes with more ill effects. The users who did report those findings, also said the side effects seemed to diminish after they lowered the dosage.

Ibutamoren stacks well with SARMS and prohormones.

Select your currency
Select the fields to be shown. Others will be hidden. Drag and drop to rearrange the order.
  • Image
  • SKU
  • Rating
  • Price
  • Stock
  • Availability
  • Add to cart
  • Description
  • Content
  • Weight
  • Dimensions
  • Additional information
  • Attributes
  • Custom attributes
  • Custom fields
Click outside to hide the compare bar
Compare
Compare ×
Let's Compare! Continue shopping
Shopping cart close