andarine s4 benefits dosages blog

Andarine S4: Benefits, Dosages (Complete Guide)

Andarine (also known as S4) is a powerful selective androgen receptor modulator which can support muscle growth, mass, and density. This article will tell you everything you need to know about this increasingly favourable compound.

What Is Andarine S4?

Andarine S4 is a SARM (a selective androgen receptor modulator) sometimes also known as SARM S4. Like many SARMs, it has positive benefits on muscle mass, muscle gain and anabolism (helping you build muscle tissue and minimise muscle loss). But Andarine is stronger and more potent than many other SARMs.

Different SARMs have different levels of potency and this shows up in the results you can expect (and in what timeframe). What you need to know about Andarine is that it is pretty strong as SARMs go – so you can expect measurable results in a short time frame.

But there are some side effects to watch out for and we’ll detail those further in this article. However, Andarine is selective in which receptors it binds too, so side effects should be minimal if you are healthy and stick to recommended dosages.

Andarine works by binding to androgen receptors (in muscle tissue and bone tissue) which encourages your body to grow muscle. As a by-product of this, you’ll get stronger in the gym, you’ll be able to lift more and recover faster which will lead to yet more muscle gain.

Andarine S4 has been through human trials but no studies were published. There is some limited information which suggests that S-4 was described as the ideal SARM due to its single-day dosing, complete oral bioavailability and significant anabolic effects.

Understand The Benefits Of Andarine S4

Andarine can be used for bulking, cutting, body recomposition, strength gains, or competition prep but please remember you can not use Andarine – or any SARM – if you compete in drug-tested sport, including tested bodybuilding competitions because SARMs are banned by WADA.

  1. Dense muscle tissue – Andarine is renowned for giving that hard, dry look to muscles (which is why bodybuilder like it). Ideal if you want a full, pumped look
  2. Fat loss – Andarine seems to help with fat loss, possibly because it increases the metabolism of body fat and suppresses HSL (hormone-sensitive lipase)
  3. Strength gains – Andarine helps you build strength, and you may notice significant strength gains within a few weeks
  4. Dry gains – you shouldn’t experience water retention with SARM S4, meaning your muscle gains will look dry, not watery
  5. High bioavailability – meaning Andarine is absorbed into your system quickly, so it gets to work rapidly, even at low doses

You can see why S-4 is popular with bodybuilders, powerlifters, and other strength and power athletes. Just be careful with tested competition – like we’ve said, Andarine is banned (as are all SARMs) by WADA.

Are There Any Side Effects Of Andarine S4?

You should stay open to the possibility of side effects with any compound or medicine. Andarine is no different. Remember, SARMs were originally developed as potential medical solutions to physical issues, and most drugs have some potential side effects.

So what are the side effects of Andarine, and how can you minimise the chance of them happening? There are two key side effects to be aware of:

  • Night vision disturbance – some people report a kind of yellow tinge to their vision at night (probably because SARM S4 binds to receptors in the eyes). This shouldn’t be a problem – unless you work shifts, or need to drive or operate any kind of machinery at night. Most of these reports come from people taking high doses of Andarine.
  • Testosterone suppression – S4 does impact your natural test levels, and you will need to do a PCT (post cycle therapy) after using Andarine. Another way to keep this risk to a minimum is to run short cycles of 8 weeks maximum.

How To Use Andarine, Best Dosages

The best way to minimise the risks of any side effects is to get informed about how to use Andarine. This includes how much (dosages), how often (should you split the dose), and for how long (cycle length).

Andarine is a strong SARM, which means you can see good results even at low doses, so there is no need to take high doses – in fact, this just opens you up to more risk of side effects, for no need.

  • Start with 20mg-25mg Andarine a day.
  • Split your dose (whatever dose you take) into 2-3 doses per day. Take a dose in the morning, and one with your pre-training meal. If you are taking 1/3 dose, do this 4 hours after your previous dose.
  • After 2 weeks, assess your progress and results
  • If your progress has slowed down or stopped, increase the dose by 5mg per week for the rest of your cycle.
  • Do not keep increasing the dose all the while you are getting results – only increase it if your results stop.
  • Never go higher than 50mg/day (in fact, 35mg/day is a high dose).
  • Never take Andarine S4 for longer than 8 weeks (6-8 weeks is the least risky).

Andarine vs Other Popular SARMs

S4 is sometimes stacked with Ostarine (for cutting). Ostarine can be beneficial for building muscle mass and body recomposition. Andarine can also be stacked with Cardarine (for strength training), or with Ligandrol (for bulking). Remember, Andarine is already a strong SARM so there is no real need to stack.

Andarine S4 is a powerful SARM which is a kind of all-rounder, helping build muscle mass, burn body fat, and boost strength. But remember it is banned by WADA and can not be used for any tested sport or competition.

5 amazing benefits of ostarine mk-2866

5 Surprising Benefits of Ostarine MK-2866

Discover everything you need to know about the popular SARM Ostarine, also known as MK-2866. Ostarine is one of the most popular SARMs in the bodybuilding and physique world – no surprise once you learn about the potential effects of this research-backed compound.

What Is Ostarine?

If you’ve been around the bodybuilding or physique sport world for even a short while, you’ve probably heard about Ostarine. But what is this compound, why do some people use it, and should you consider it (or should you look for a better alternative)? To begin, it’s worth mentioning that this is widely considered one of the safest anabolic SARMs on the market.

MK-2866 is a SARM (Selective Androgen Receptor Modulator) which is popular with strength, power and physique athletes who are looking for ways to boost muscle mass and strength with fewer or no side effects compared to harsher compounds such as steroids or prohormones. It was originally developed to help treat muscle-wasting conditions, so you can understand why bodybuilders are drawn to it. It preserves lean tissue when conditions would usually lead to catabolism (for example, dieting or high-frequency training).

How Does MK-2866 Work?

Like any SARM, MK-2866 can mimic testosterone (the primary anabolic hormone), stimulates the body’s androgen receptors and boosts the steroid hormone receptors. It can activate stem cells, helping to regenerate and build muscle and bone tissue – exactly what bodybuilders want. For this reason, MK-2866 is thought to have fewer side-effects than anabolic steroids because SARMs do not affect the organs. They are very selective by their very nature, which is the main advantage of any SARM. Of course, this can change if someone stacks Ostarine with an anabolic steroid.

Ostarine is renowned for improving both training performance (strength and power) and physique appearance (through bigger, denser muscle mass). However, its noteworthy advantage is injury repair and recovery; it has an excellent affinity for joint repair in particular.

Muscle Gain & Recovery with MK-2866

One reason many bodybuilders use MK-2866 is for its impact on the IGF-1 gene, as well as muscle cells and cells in connective tissues. Ostarine may stimulate these cells which means faster recovery from training stress. Less time out for recovery (or less soreness during your next training session) means you can train more frequently, achieving a greater workload across the training week. This is likely to result in greater muscle growth from the training stimulus.

In one human study of 120 healthy elderly people, Ostarine significantly increased lean muscle mass as well as fitness levels with no side effects or steroid-like risks.

5 Potential Effects Of Ostarine

There are five key reasons a bodybuilder might choose to use Ostarine.

#1 Muscle gain
The SARM is often used as a compound to aid muscle gain because of its effect on stimulating muscle cells. Not only does this mean you may gain additional muscle tissue but you are likely to protect the muscle mass you already have (important during a fat loss phase).

#2 Recovery
It can mean faster recovery from DOMS and training fatigue. This means you can train more frequently and you can push harder during each session.

#3 Fat loss
It is thought to slow or stop muscle breakdown (catabolism) whilst the body is getting leaner. This means you can push harder during a dieting phase without the usual worry about losing muscle, resulting in the holy grail of lean gains.

#4 Cardiovascular health
Ostarine can have a number of benefits for heart health, including reduction of triglycerides, reduced lipids and reduced total cholesterol. It may also help lower blood glucose levels and improve insulin resistance.

#5 Increased metabolic rate
It is thought to increase base metabolic rate, meaning you will burn more calories during training, NEAT and cardio. It can also increase endurance and give you better stamina, which will also mean longer more intense training sessions. All these combined means you are likely to burn more calories – good news if you are trying to get shredded.

How Long Does MK-2866 Take to Work?

As with most supplements, one of the most commons questions asked is how long MK-2866 takes to work. Anecdotal evidence shows that people tend to feel a great sense of ‘wellbeing’ within 2-3 days of using Ostarine. A sense of vitality, positive mood, good energy and holistic ‘balance’.

Many bodybuilders and athletes report noticeable consistent strength gains within the first 2-3 weeks of using the compound. In terms of physical changes; body composition and muscle definition, results will usually be seen to the eye from 4 weeks onwards, however, it’s important to understand that this ultimately comes down to so many individual factors. Your current body composition, your goals, your training and diet, as well as recovery protocols. Everyone will respond to different compounds in different ways whilst your efforts and commitment will play an even bigger part in how quickly you see results.

Ostarine & Bodybuilding

MK-2866 is best known for is building muscle and burning fat – two things all bodybuilders are interested in at some point during their lifting career (even if they never want to step on stage).

Muscle gain: remember how we said Ostarine was originally developed to help tackle muscle wasting diseases? People who want to build more muscle tissue, and hang on to the muscle they’ve got, can use MK-2866 to harness those anti-catabolic effects.

Fat burning: Ostarine has muscle preserving properties, meaning you can diet more aggressively or for longer without losing muscle tissue. Retaining muscle during a diet phase means you’ll also retain more strength, so you can train harder and heavier, all leading to a positive circle of lean gains.

But there’s more than muscle building and boosted fat-burning abilities. Ostarine can also boost bone health, help reduce LDL and triglycerides and improve insulin resistance. These are all things which can be attractive to bodybuilders looking to gain mass and strength.

How to Stack Ostarine

Bodybuilders use Ostarine in a few different ways. This is what you need to know.

Using Ostrarine by itself: Ostarine MK-2866 can be used alone. It should be used as a cycle (like any SARM) of 12 weeks for men, up to 8 weeks for women. Men should use between 15-25mg and women should use 5-10mg. Ostarine has a half-life of 24 hours so there is no need to split the dose across the day.

With other SARMs: bodybuilders typically stack Ostarine with other popular SARMs, like Ibutamoren MK677 or Ligandrol LGD-4033. Ostarine can also be used in a so-called “triple SARM” stack of Ostarine plus Andarine and Cardarine (although Cardarine isn’t a true SARM).

Choose The Best Ostarine Supplement

Like any SARM, it’s important you choose the best-quality Ostarine MK-2866 supplement. Don’t go for the cheapest product. Check the label carefully and look for smart ingredients which are designed to optimise the product’s effectiveness so you see the best gains.

We love our best selling Mutagenic Labz Ostagainz, which delivers 10mg of pure Ostarine MK-2866 along with Piperine in every dose (to aid digestion and absorption). It’s non-liver-toxic, has no androgenic activity, and promises minimal side effects – with maximum results. Click here to try it for yourself. Choose an Ostarine product you can trust, backed by a reliable name in bodybuilding supplements.

We should point out that Ostarine – like all SARMs – is not approved for use in tested strength and physique sports but for those of you who don’t want to compete with the tested federations? There are so many reasons to try Ostarine by itself or as a stack, whether you’re dieting, bulking, or aiming for a body recomposition phase.

Dry Gains with M-Sten (25lbs in 4 Weeks)

Insane Dry Gains with M-Sten (25lbs in 4 Weeks)

If you’ve taken an interest in prohormones, there’s no doubt you’ve heard about M-Sten, or Methyl Sten, short for Methylstenbolone, which was first brought to the market as Ultradrol.

Methystenbolone is one of the strongest prohormones on the market which makes it one of the most popular bulking compounds in the prohormone category. Where M-Sten stands out from the rest is the quality of lean muscle gain; its advantage is very little water retention, greater vascularity and definition.

Another advantage of M-Sten is that it doesn’t convert to estrogen. That means no problems “down below”, either with performance or bladder.

Methylstenbolone is banned by WADA so is not recommended for drug-tested athletes.

What are the Benefits of Methylstenbolone?

Gains of an M-Sten cycle are impressive, with a reported lean mass gain of up to 25 lbs in 4 weeks. What you can expect from an M-Sten cycle:

  • Dry gains – minimal water retention
  • Doesn’t convert to estrogen
  • Boosts strength levels
  • Helps promote the development of fuller muscles
  • Considerable size and mass gains
  • Allows you to train longer and harder, which means you get results quicker
  • There are quite a few reports about 3% body fat reduction while gaining as much as 6 pounds of muscle in a 4-week cycle

How to Cycle M-Sten

Gearing up for lean muscle gain means you need to eat more and better than usual; your diet should be on point for best results. Drink lots of water – M-Sten is not liver-friendly. For the same reason, avoid alcohol, that’s the last thing your liver needs on a prohormone cycle. Do it right and you’ll be seeing results in the first couple of weeks.

We recommend 4 weeks on M-Sten initially, and no more than 6 for experienced users.

Depending on your goals, you can adapt your dosages – for cutting, lower dosages work perfectly, whereas for bulking, tapering up the dosage will optimise results. Here are a few protocols you might want to consider:

Newbie Users: 4-week cycle (Week 1-2, 1 capsule per day
, Week 3-4, 2 capsules per day)

Experienced Users: 4-week cycle (Week 1, 1 capsule per day
, Week 2-4, 2 capsules per day)

Advanced Users: 4-week cycle (
Week 1, 1 capsule per day
, Week 2-3, 2 capsules per day
, Week 4, 3 capsules per day)

Do I need to run PCT after a Methylstenbolone Cycle?

Yes. It’s not just your cycle that matters; your Post Cycle Therapy is the phase that makes all the difference. Having a solid PCT protocol will ensure you keep your gains, restore your testosterone levels, balance your hormones and ensure you don’t suffer from those ‘post-cycle blues’. Run your PCT for 4 weeks – we recommend the Mutagenic Labz Regen-T (Total PCT).

Another little-known secret to the perfect PCT is bridging your prohormone cycle with SARMs.

Signs that show you need to pay more attention to your PCT:

  • Feeling tired when you normally wouldn’t
  • Being more aggressive and not knowing why
  • Lower sex drive
  • Back pumps (taurine can help)
  • Joint pain

What are the Side Effects of M-Sten?

It’s not all good news though, but you knew that, right? M-Sten is pretty toxic, to avoid liver damage you’re going to need a quality liver support such as Mutagenic Labz TUDCA Plus.

M-Sten can affect your kidneys too; if you get dark urine while you’re using, that’ll be down to elements that aren’t being metabolized by your body.

M-Sten can also affect your blood pressure and cholesterol, so maintaining a good diet is critical.

Although it doesn’t convert to estrogen, any prohormone will mess with your hormone levels, which means estrogen could be produced because of other factors.

Stacking M-Sten

The Mutagenic Labz Hulk Stack includes M-Sten, Assimilation and Metamorphosiz.

  • Ideal for: Lean Bulking, Cutting/Shredding, Strength, Endurance, Fullness, Huge Pumps, Vascularity, Lean Mass Gain
  • No Bloating or water retention
  • Does not aromatise
  • Highly anabolic
  • Cycle protocol: 4 weeks (8 weeks off)
LGD-4033: Amazing Benefits of Ligandrol

LGD-4033: Amazing Benefits of Ligandrol

Hailed as the ‘King of SARMs’, LGD-4033, also known as Ligandrol or LGD for short, is quickly becoming the SARM of choice for bodybuilders, weightlifters, crossfitters and even fitness models. In the bodybuilding world, SARMs are often used as a safer substitute for anabolic steroids. SARMs have many of the advantages of steroids without the nasty side effects but the purpose for taking them both remains the same; to enhance fat loss while building muscle, to improve performance and strength, as well as to promote healing and recovery.

See our guide to Bridging Prohormone Cycles with SARMs.

Dropping fat while you’re trying to increase muscle mass seems counter-intuitive and with good reason. Biology doesn’t like the idea in general, so if you’re trying to achieve this effect you’re going to need some help. Ligandrol is probably the most effective. It’s taken orally and was developed to combat muscle-wasting conditions and osteoporosis.

How Does LGD-4033 Work?

LGD-4033 binds itself to targeted androgen receptors in muscle tissue. It is this selective nature which allows Ligandrol to be taken orally rather than by injection. Because of its selective nature, LGD-4033 naturally avoids major organs which makes it a lot safer than some of the alternatives and especially steroids.

LGD-4033 increases the body’s testosterone levels, which promotes muscle growth, improves the amount of energy produced by the body and generally boosts blood circulation. There has been some suggestion that LGD-4033 also improves bone density which would make sense considering its potential as a treatment for osteoporosis.

The Benefits of Ligandrol

The many benefits of Ligandrol reflect its extremely popular status as one of the best SARMs on the market today:

  • Promotes lean and dry muscle mass gains
  • Sustainable results, even at lower doses
  • Boosts fat loss
  • Increases libido
  • Increases stamina and endurance
  • Promotes recovery
  • Considered the best SARM for bulking amongst many
  • Ideal for body recomposition (losing body fat whilst gaining muscle)
  • Stacks brilliantly with Cardarine for effective cutting cycles
  • Gives amazing pumps and fullness
  • Increases cardiovascular strength by week 3
  • Gives a heightened sense of wellbeing without mood swings or crashes
  • More powerful than Ostarine
  • The closest SARM you can get to testosterone
  • No bloating or water retention
  • No male-pattern hair loss
  • No liver damage
  • No changes in cholesterol or blood pressure

LGD-4033 Increases Libido

SARMs are selective in their nature but they also affect the brain and offer a host of cognitive benefits. This explains their positive effects on libido and mood enhancement. There have been many anecdotal reports supporting that LGD4033 can greatly improve cognition, libido and energy; most users report an increased sense of wellbeing and stamina when using this SARM.

Ligandrol Side-Effects

Ligandrol is still new and there hasn’t been a great deal of research on it. The few studies that do exist suggest the SARM is easily tolerated by the body and few if any side effects have been recorded.

The studies and other anecdotal evidence does suggest that users will experience very slight suppression. In most cases, there is no need for a PCT but some may prefer to run a mild over-the-counter PCT supplement and a Testosterone Booster to optimise natural testosterone levels post-cycle.

LGD-4033 doesn’t increase estrogen levels so there is no risk of man boobs, puffy nipples or water retention.

Although safer than some of the other SARMs on the market and clearly safer than steroids, there is some anecdotal evidence to suggest that Ligandrol can cause headaches and nausea.


The few studies that have taken place suggest that doses as low as 1mg per day are enough to have a significant effect on muscle growth and that doses as high as 25mg showed little, to no, side effects.

An entry-level dose of 5mg per day rising to 10mg if you’re on the heavier side. The results that have come in suggesting that a cycle of 2-3 weeks is enough to cause a significant effect but 4-8 weeks is ideal.

How to Take LGD-4033

The half-life of LGD 4033 is 24–36 hours, therefore it can be taken just once per day. Keep in mind is that its long half-life means that the levels of LGD-4033 will gradually build up in your system over the course of your cycle. Studies showed that blood levels nearly tripled after 3 weeks compared to the first day.

While most SARMS are often stacked together for optimum results, a lot of users see great results with LGD-4033 as a standalone. Stacking Ligandrol works best with MK-677, Cardarine, Ostarine and Testolone RAD-140.

In conclusion

LGD-4033 is a potent yet safe SARM that stacks well with other SARMs, prohormones and supplements, and the fact it can be taken orally is a bonus.

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